Biologist gains insight into genetic evolution of birds
2014-12-11
Lincoln, Neb., Dec. 11, 2104 -- A University of Nebraska-Lincoln researcher has contributed to discoveries about bird evolution as part of a new study that sequenced the complete genomes of 45 avian species.
Published Dec. 11 in the journal Science, the study found that avian genomes -- the complete archive of genetic material present in cells -- have exhibited surprisingly slow rates of evolution when compared with their mammalian counterparts.
Jay Storz, a Susan J. Rosowski Associate Professor of Biological Sciences, led a research group that assisted the study by examining ...
Low income kids eat more fruits and vegetables when they are in school
2014-12-11
The fruits and vegetables provided at school deliver an important dietary boost to low income adolescents, according to Meghan Longacre, PhD and Madeline Dalton, PhD of Dartmouth Hitchcock's Norris Cotton Cancer Center and The Hood Center for Children and Families. In a study released in Preventive Medicine, Longacre and Dalton found that fruit and vegetable intake was higher among low income adolescents on days when they consumed meals at school compared to days when low income adolescent were not in school. The opposite was true for high income adolescents who consumed ...
Understanding how emotions ripple after terrorist acts
2014-12-11
PITTSBURGH--The 2013 Boston Marathon bombing motivated mass expressions of fear, solidarity, and sympathy toward Bostonians on social media networks around the world. In a recently released study, researchers at the University of Pittsburgh and Cornell University analyzed emotional reactions on Twitter in the hours and weeks following the attack.
The study is the first large-scale analysis of fear and social-support reactions from geographically distant communities following a terrorist attack. The findings show the extent to which communities outside of Boston expressed ...
Penn research outlines basic rules for construction with a type of origami
2014-12-11
Origami is capable of turning a simple sheet of paper into a pretty paper crane, but the principles behind the paper-folding art can also be applied to making a microfluidic device for a blood test, or for storing a satellite's solar panel in a rocket's cargo bay.
A team of University of Pennsylvania researchers is turning kirigami, a related art form that allows the paper to be cut, into a technique that can be applied equally to structures on those vastly divergent length scales.
In a new study, the researchers lay out the rules for folding and cutting a hexagonal ...
Happy-go-lucky CEOs score better returns
2014-12-11
A CEO's natural sunny disposition can have an impact on the way the market reacts to announcements of company earnings, according to research from the University of British Columbia's Sauder School of Business.
The study shows that leaders' inclinations to express themselves with optimism carries over into their tone when disclosing company performance - a tendency that can create an uptick in stock price.
"Ours is the first study to look at the effect of how managers naturally convey themselves," says Sauder Assistant Professor Jenny Zhang, who co-authored the paper. ...
Senescent cells play an essential role in wound healing
2014-12-11
Senescent cells have a bad-guy reputation when it comes to aging. While cellular senescence - a process whereby cells permanently lose the ability to divide when they are stressed - suppresses cancer by halting the growth of premalignant cells, it is also suspected of driving the aging process. Senescent cells, which accumulate over time, release a continual cascade of inflammatory cytokines, chemokines, growth factors and proteases. It is a process that sets up the surrounding tissue for a host of maladies including arthritis, atherosclerosis and late life cancer. But ...
Affluence, not political complexity, explains the rise of moralizing world religions
2014-12-11
The ascetic and moralizing movements that spawned the world's major religious traditions--Buddhism, Islam, Judaism, Hinduism, and Christianity--all arose around the same time in three different regions, and researchers reporting in the Cell Press journal Current Biology on December 11 have now devised a statistical model based on history and human psychology that helps to explain why. The emergence of world religions, they say, was triggered by the rising standards of living in the great civilizations of Eurasia.
"One implication is that world religions and secular spiritualities ...
Scientists map the human loop-ome, revealing a new form of genetic regulation
2014-12-11
EMBARGOED for release Thursday, Dec. 11, 2014, at 12 p.m. ET
HOUSTON - (Dec. 11, 2014) - The ancient Japanese art of origami is based on the idea that nearly any design - a crane, an insect, a samurai warrior - can be made by taking the same blank sheet of paper and folding it in different ways.
The human body faces a similar problem. The genome inside every cell of the body is identical, but the body needs each cell to be different -an immune cell fights off infection; a cone cell helps the eye detect light; the heart's myocytes must beat endlessly.
Appearing online ...
New targeted drugs could treat drug-resistant skin cancer
2014-12-11
Clinical trials to test the new drugs in patients should begin as early as 2015.
Existing drugs target faulty versions of a protein called BRAF which drives about half of all melanomas, but while initially very effective, the cancers almost always become resistant to treatment within a year.
The new drugs - called panRAF inhibitors - could be effective in patients with melanoma who have developed resistance to BRAF inhibitors.
The new study was funded by the Wellcome Trust and Cancer Research UK, and jointly led by scientists at The Institute of Cancer Research, ...
Getting antibodies into shape to fight cancer
2014-12-11
Scientists at the University of Southampton have found that the precise shape of an antibody makes a big difference to how it can stimulate the body's immune system to fight cancer, paving the way for much more effective treatments.
The latest types of treatment for cancer are designed to switch on the immune system, allowing the patient's own immune cells to attack and kill cancerous cells, when normally the immune cells would lie dormant.
In a study, funded by Cancer Research UK and published in the journal Cancer Cell, the Southampton team have found that a particular ...
Herpes virus rearranges telomeres to improve viral replication
2014-12-11
PHILADELPHIA - (Dec. 11, 2014) - A team of scientists, led by researchers at The Wistar Institute, has found that an infection with herpes simplex virus 1 (HSV-1) causes rearrangements in telomeres, small stretches of DNA that serve as protective ends to chromosomes. The findings, which will be published in the Dec. 24 edition of the journal Cell Reports, show that this manipulation of telomeres may explain how viruses like herpes are able to successfully replicate while also revealing more about the protective role that telomeres play against other viruses.
"We know ...
The story of a bizarre deep-sea bone worm takes an unexpected twist
2014-12-11
The saga of the Osedax "bone-eating" worms began 12 years ago, with the first discovery of these deep-sea creatures that feast on the bones of dead animals. The Osedax story grew even stranger when researchers found that the large female worms contained harems of tiny dwarf males.
In a new study published in the Dec. 11 issue of Current Biology, marine biologist Greg Rouse at Scripps Institution of Oceanography at UC San Diego and his collaborators reported a new twist to the Osedax story, revealing an evolutionary oddity unlike any other in the animal kingdom. Rouse's ...
3-D maps reveal the genome's origami code
2014-12-11
HOUSTON -- (Dec. 11, 2014) -- In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation -- a kind of "genomic origami" that allows the same genome to produce different types of cells. The research appears online today in Cell.
A central goal of the five-year project, which was carried out at Baylor College of Medicine, Rice University, the Broad Institute and Harvard University, was to identify the loops in the human genome. Loops form when two bits of DNA that ...
UB research raises consciousness for dehydration concerns in diabetic patients
2014-12-11
BUFFALO, N.Y. -- Some drugs used to treat diabetes mimic the behavior of a hormone that a University at Buffalo psychologist has learned controls fluid intake in subjects. The finding creates new awareness for diabetics who, by the nature of their disease, are already at risk for dehydration.
Derek Daniels' paper "Endogenous Glucagon-Like Peptide-1 Reduces Drinking Behavior and Is Differentially Engaged by Water and Food Intakes in Rats," co-authored with UB psychology graduate students Naomi J. McKay and Daniela L. Galante, appears in this month's edition of the Journal ...
Middle East respiratory syndrome coronavirus unlikely to reach epidemic status
2014-12-11
London, United Kingdom, December 11, 2014 - Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging virus, with the first case reported in 2012. It exhibits a 40% fatality rate and over 97% of the cases have occurred in the Middle East. In three new studies in the current issue of the International Journal of Infectious Disease, researchers reported on clinical outcomes in the Kingdom of Saudi Arabia (KSA), how long patients will shed virus during their infections, and how the Sultanate of Oman is dealing with cases that have appeared there. An editorial ...
Youngest bone marrow transplant patients at higher risk of cognitive decline
2014-12-11
(MEMPHIS, Tenn. - December 11, 2014) Toddlers who undergo total body irradiation in preparation for bone marrow transplantation are at higher risk for a decline in IQ and may be candidates for stepped up interventions to preserve intellectual functioning, St. Jude Children's Research Hospital investigators reported. The findings appear in the current issue of the Journal of Clinical Oncology.
The results clarify the risk of intellectual decline faced by children, teenagers and young adults following bone marrow transplantation. The procedure is used for treatment of cancer ...
Decoding fat cells: UR discovery may explain why we gain weight
2014-12-11
University of Rochester researchers believe they're on track to solve the mystery of weight gain - and it has nothing to do with indulging in holiday eggnog.
They discovered that a protein, Thy1, has a fundamental role in controlling whether a primitive cell decides to become a fat cell, making Thy1 a possible therapeutic target, according to a study published online this month by the FASEB Journal.
The research brings a new, biological angle to a problem that's often viewed as behavioral, said lead author Richard P. Phipps, Ph.D. In fact, some diet pills consist of ...
Can a biomarker in the blood predict head fracture after traumatic brain injury?
2014-12-11
New Rochelle, NY, December 11, 2014--In cases of traumatic brain injury (TBI), predicting the likelihood of a cranial lesion and determining the need for head computed tomography (CT) can be aided by measuring markers of bone injury in the blood. The results of a new study comparing the usefulness of two biomarkers released into the blood following a TBI are presented in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free on the Journal of Neurotrauma website at http://online.liebertpub.com/doi/full/10.1089/neu.2013.3245 ...
Roller coaster rides trigger pediatric stroke
2014-12-11
MAYWOOD, Il. - Riding a couple roller coasters at an amusement park appears to have triggered an unusual stroke in a 4-year-old boy, according to a report in the journal Pediatric Neurology.
The sudden acceleration, deceleration and rotational forces on the head and neck likely caused a tear in the boy's carotid artery. This tear, called a dissection, led to formation of a blood clot that triggered the stroke, Loyola University Medical Center neurologist Jose Biller, MD and colleagues report.
Strokes previously have been reported in adult roller coaster riders, but ...
WPI team develops tool to better classify tumor cells for personalized cancer treatments
2014-12-11
Worcester, Mass. - A new statistical model developed by a research team at Worcester Polytechnic Institute (WPI) may enable physicians to create personalized cancer treatments for patients based on the specific genetic mutations found in their tumors.
Just as cancer is not a single disease, but a collection of many diseases, an individual tumor is not likely to be comprised of just one type of cancer cell. In fact, the genetic mutations that lead to cancer in the first place also often result in tumors with a mix of cancer cell subtypes.
The WPI team developed a new ...
NASA sees Hagupit weaken to a depression enroute to Vietnam
2014-12-11
The once mighty super typhoon has weakened to a depression in the South China Sea as it heads for a final landfall in southern Vietnam. NASA's Aqua satellite captured an image of the storm that showed it was weakening.
NASA's Aqua satellite passed over Hagupit on Dec. 11 at 05:20 UTC (12:20 a.m. EST) and the MODIS instrument captured a visible image of the storm. The MODIS image showed that the thunderstorms had become fragmented around the circulation center.
On Dec. 11 at 1500 UTC (10 a.m. EST) Tropical Depression Hagupit's maximum sustained winds dropped to 30 knots ...
SwRI scientists develop solar observatory for use on suborbital manned space missions
2014-12-11
San Antonio -- December 11, 2014 -- Southwest Research Institute (SwRI) is preparing to unveil a new, miniature portable solar observatory for use onboard a commercial, manned suborbital spacecraft. The SwRI Solar Instrument Pointing Platform (SSIPP) will be on exhibit at the fall meeting of the American Geophysical Union (AGU), Dec. 16-19, at the Moscone Center in San Francisco, Calif.
Using reusable suborbital commercial spacecraft for the SSIPP development effort improves on a traditional space instrument development process that goes back to the dawn of the space ...
Many US workers are sacrificing sleep for work hours, long commutes
2014-12-11
DARIEN, IL - A new study shows that paid work time is the primary waking activity exchanged for sleep and suggests that chronic sleep loss potentially could be prevented by strategies that make work start times more flexible.
Results show that work is the dominant activity exchanged for less sleep across practically all sociodemographic categories. Compared to normal sleepers, short sleepers who reported sleeping 6 hours or less worked 1.55 more hours on weekdays and 1.86 more hours on weekends or holidays, and they started working earlier in the morning and stopped working ...
Surgical robot adopters use more of recommended procedure for kidney cancer, reports Medical Care
2014-12-11
December 11, 2014 - Hospitals with robotic surgical systems are more likely to perform "nephron-sparing" partial nephrectomy--a recommended alternative to removal of the entire kidney--in patients with kidney cancer, reports a study in the December issue of Medical Care. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.
"Hospital acquisition of the surgical robot is associated with greater proportion of partial nephrectomy, an underutilized, guideline-encouraged procedure," write Dr Ganesh Sivarajan of New York University Langone ...
Interstellar mystery solved by supercomputer simulations
2014-12-11
An interstellar mystery of why stars form has been solved thanks to the most realistic supercomputer simulations of galaxies yet made.
Theoretical astrophysicist Philip Hopkins of the California Institute of Technology (CalTech) led research that found that stellar activity -- like supernova explosions or even just starlight -- plays a big part in the formation of other stars and the growth of galaxies.
"Feedback from stars, the collective effects from supernovae, radiation, heating, pushing on gas, and stellar winds can regulate the growth of galaxies and explain why ...
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