Highlight In an observational study that followed participants for an average of just under 3 years, a "trade-off" of sedentary activity with low-intensity activity was not beneficial, but a trade-off of 2 minutes/hour of sedentary activity with an equal amount of light-intensity activity was associated with 33% lower risk of dying in the general population and a 41% lower risk of dying in the individuals with chronic kidney disease. Previous research suggests that sitting for long periods of time may increase the risk of disease and early death. Washington, DC ...

A new study by Johns Hopkins researchers concludes that most U.S. clinical registries that collect data on patient outcomes are substandard and lack critical features necessary to render the information they collect useful for patients, physicians and policy makers. Findings of the study, published ahead of print April 24 in the Journal for Healthcare Quality, reveal poor data monitoring and reporting that researchers say are hurting national efforts to study disease, guide patient choice of optimal treatments, formulate rational health policies and track in a meaningful ...

"The word, virus, connotes morbidity and mortality, but that bad reputation is not universally deserved," said Marilyn Roossinck, PhD, Professor of Plant Pathology and Environmental Microbiology and Biology at the Pennsylvania State University, University Park. "Viruses, like bacteria, can be important beneficial microbes in human health and in agriculture," she said. Her review of the current literature on beneficial viruses appeared ahead of print April 24 in the Journal of Virology, which is published by the American Society for Microbiology. In sharp contrast to ...

Scientists require high-resolution imaging of plant cells to study everything from fungal infections to reproduction in maize. These images are captured with scanning electron microscopy (SEM), where an electron microscope focuses beams of electrons to increase magnification of objects. SEM is a common technique for all fields of science. However, preparing objects for SEM and other common imaging methods can compromise delicate biological samples. Freeze-drying of material, electron beams, and vacuum pressure in the microscope can all result in cell damage, which is ...

New research has shown that children who display increasing levels of inattention at the age of seven are at risk of worse academic outcomes in their GCSE examinations. Researchers at the Universities of Nottingham and Bristol studied more than 11,000 children as part of the research which was funded by the Economic and Social Research Council (ESRC) and is published in the Journal of the American Academy of Child and Adolescent Psychiatry. The findings of the research have a range of implications for parents, teachers and clinicians. The research was led by Kapil ...

If you're in the market for a new car, and especially if you have a trade-in, the latest research from the USC Marshall School of Business marketing department suggests you aren't getting the deal you think you are getting. New research from USC Marshall School of Business associate professors of marketing Anthony Dukes and Sivaramakrishnan Siddarth shows that a consumer with a trade-in actually forks over more money to the dealer than consumers without a trade-in. "The Informational Role of Product Trade-Ins for Pricing Durable Goods" is forthcoming in the Journal ...

Results to be published in the Journal of Family and Economic Issues suggest that having short-term household debt -- credit cards and overdue bills -- increases depressive symptoms. The association is particularly strong among unmarried people, people reaching retirement age and those who are less well educated, according to a new study by lead author Lawrence Berger of the University of Wisconsin-Madison. These are the first results to show the impact of different types of debt on depression and their effects on different sectors of the US population. Little evidence ...

Scientists are using a variety of buoys and autonomous underwater vehicles to record and archive sounds from marine mammals and fish species in the western North Atlantic through a new listening network known as the U.S. Northeast Passive Acoustic Sensing Network (NEPAN). Stretching from the northern Gulf of Maine to the New York Bight in the northwest Atlantic Ocean, NEPAN provides year-round, long-term information on the presence and physical distribution of vocal whales, dolphins and porpoises and some fish species. The archived and near-real-time data comes from recorders ...

Researchers at Aalto University (Finland) and Amherst College (USA) have observed a point-like monopole in a quantum field itself for the first time. This discovery connects to important characteristics of the elusive monopole magnet. The results were just published in Science magazine. The researchers performed an experiment in which they manipulated a gas of rubidium atoms prepared in a nonmagnetic state near absolute zero temperature. Under these extreme conditions they were able to create a monopole in the quantum-mechanical field that describes the gas. 'In this ...

LA JOLLA -- A study tying the aging process to the deterioration of tightly packaged bundles of cellular DNA could lead to methods of preventing and treating age-related diseases such as cancer, diabetes and Alzheimer's disease, as detailed April 30, 2015, in Science. In the study, scientists at the Salk Institute and the Chinese Academy of Science found that the genetic mutations underlying Werner syndrome, a disorder that leads to premature aging and death, resulted in the deterioration of bundles of DNA known as heterochromatin. The discovery, made possible through ...

HOUSTON - (April 30, 2015) - With the Millennium Development Goals established by the United Nations in 2000 coming to an end in 2015, and the new Sustainable Development Goals now in the works to establish a set of targets for the future of international development, experts at Baylor College of Medicine have developed a new tool to show why neglected tropical diseases, the most common infections of the world's poor, should be an essential component of these goals. Using World Health Organization data for the number people at risk of parasitic worm infections in each ...

A detailed study of marine animals that died out over the past 23 million years can help identify which animals and ocean ecosystems may be most at risk of extinction today, according to an international team of paleontologists and ecologists. In a paper to be published in the May 1 issue of the journal Science, researchers from the University of California, Berkeley, and other institutions report that worldwide patterns of extinction remained remarkably similar over this period, with the same groups of animals showing similar rates of extinction throughout and with a ...

Demand for seafood from wild fisheries and aquaculture around the world has nearly doubled over the past four decades. In the past several years, major retailers in developed countries have committed to source their seafood from only sustainably certified fisheries and aquaculture, even though it is not clear where that supply will come from. A team of researchers led by the University of California, Davis, has focused its attention on fishery improvement projects, or FIPs, which are designed to bring seafood from wild fisheries to the certified market, with only a promise ...

HIV-1 continues to spread globally. While neither a cure, nor an effective vaccine are available, recent focus has been put on 'treatment-for-prevention', which is a method by which treatment is used to reduce the contagiousness of an infected person. A study published this week in PLOS Computational Biology challenges current treatment paradigms in the context of 'treatment for prevention' against HIV-1. Sulav Duwal, Max von Kleist and their collaborators develop and employ optimal control theory to compute and assess diagnostic-guided vs. pro-active treatment strategies ...

Proteins inside a cell are in constant motion, changing shape continuously in order to carry out their functions. In addition, their multiple component atoms each have individual patterns of motion, making the entire protein a system of non-stop highly complex movement. Understanding how a protein moves is the key to developing drugs that can efficiently interact with it. But because of this complexity, protein motion has been notoriously difficult to study. Scientists at EPFL, IBS-Grenoble, and ENS-Lyon, have developed a new method for studying protein motion by first ...

The fossil record helps to predict which kinds of animals are more likely to go extinct. When combined with information about hotspots of human impacts and climate-change predictions, Smithsonian scientists and colleagues pinpoint animal groups and geographic areas of highest concern for marine conservation in the May 1 issue of Science magazine. "Just as some groups of people are more prone to health problems like diabetes or heart disease, we can tell from the fossil record which groups of animals are naturally more likely to go extinct," said Aaron O'Dea, paleontologist ...

If you thought that a beetle with a machine gun built into its rear end was something that only exists in sci-fi movies, you should talk to Wendy Moore at the University of Arizona. Many beetles secrete foul-smelling or bad-tasting chemicals from their abdomens to ward off predators, but bombardier beetles take it a step further. When threatened, they combine chemicals in an explosive chemical reaction chamber in their abdomen to simultaneously synthesize, heat and propel their defensive load as a boiling hot spray, complete with "gun smoke." They can even precisely ...

SEATTLE, Wash. -- More than 1000 dams have been removed across the United States because of safety concerns, sediment buildup, inefficiency or having otherwise outlived usefulness. A paper published today in Science finds that rivers are resilient and respond relatively quickly after a dam is removed. "The apparent success of dam removal as a means of river restoration is reflected in the increasing number of dams coming down, more than 1,000 in the last 40 years," said lead author of the study Jim O'Connor, geologist with the U.S. Geological Survey. "Rivers quickly erode ...

CAMBRIDGE, Mass--Bombardier beetles, which exist on every continent except Antarctica, have a pretty easy life. Virtually no other animals prey on them, because of one particularly effective defense mechanism: When disturbed or attacked, the beetles produce an internal chemical explosion in their abdomen and then expel a jet of boiling, irritating liquid toward their attackers. Researchers had been baffled by the half-inch beetles' ability to produce this noxious spray while avoiding any physical damage. But now that conundrum has been solved, thanks to research by a ...

The vivid pigmentation of zebras, the massive jaws of sharks, the fight or flight instinct and the diverse beaks of Darwin's finches. These and other remarkable features of the world's vertebrates stem from a small group of powerful cells, called neural crest cells, but little is known about their origin. Now Northwestern University scientists propose a new model for how neural crest cells, and thus vertebrates, arose more than 500 million years ago. The researchers report that, unlike other early embryonic cells that have their potential progressively restricted as ...

ORANGE, Calif. - Researchers in Chapman University's Argyros School of Business and Economics and their collaborators have just published a study on the evolution of yoga in the marketplace. Assistant Professor Gokcen Coskuner-Balli, Ph.D., co-authored the study, which examined how the meaning of yoga transformed in the past three decades. The results show that yoga became decreasingly associated with spirituality and increasingly associated with medicine and fitness. The study argues that the shift in the meanings are due to the changes in how yoga gurus are trained, market ...

Flowering plants, also known as angiosperms, add an allure to the world that is unlike anything else in nature, but more importantly, they sustain us. Most of the fruits, vegetables, grains, beans, nuts, and even herbs and spices that we consume are produced by flowering plants. They all belong to the green plant branch of the tree of life, and a novel DNA analysis software program named MarkerMiner facilitates identification of genes that can be used to elucidate the evolutionary relationships between them. University of Florida (UF) biologist Srikar Chamala, working ...

Over the past 35 years, California's high-wage workers have seen steady increases in their paychecks. But low-wage workers, 4.8 million strong and about one-third of the state's workforce, earned less in inflation-adjusted dollars in 2014 than they did in 1979, according to an analysis from the University of California, Berkeley. UC Berkeley researchers analyzing U.S. Census Bureau data at the campus's Center for Labor Research and Education found that low-wage workers, defined as those earning hourly wages of $13.63 or less, have seen steady declines in their inflation-adjusted ...

As the number of bills passed by Congress declines, fewer and fewer Congressional representatives are voting across party lines, leaving only a few key representatives as collaborative voters, according to researchers. "We can't say for sure that the decline in cooperation is the sole reason that there are fewer bills being introduced or passed by Congress, but we do know the two are statistically correlated, and both have been dropping steadily over the past 60 years," said Clio Andris, lead author and assistant professor of geography at Penn State. The researchers ...

China's government and other sources say that the country's carbon-dioxide emissions flattened out between 2013 and 2014. The leveling-off was a remarkable feat that could set the country on a course to beating its own goals for lowering emissions. But this optimistic outcome hinges on China overcoming some serious energy challenges, according to an article in Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society. Steven Gibb, a senior editor at C&EN, reports that a number of factors could help explain the emissions plateau. China ...