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South Pacific Island's earliest inhabitants relied primarily on foraging, not horticulture

2014-03-06
Early Lapita inhabitants of Vanuatu, a South Pacific Island, ate fish, marine turtles, and wild or domestic animals, rather than relying on horticulture during early colonization, according to a study published March 5, 2014, in the open-access journal PLOS ONE by Rebecca Kinaston from University of Otago in New Zealand and colleagues. Around 3000 BP, human populations with cultural and biological links to South East Asian islands, a culture or people known as Lapita, sailed to Remote Oceania (islands of the tropical Pacific Ocean) with domestic plants and animals, a ...

New guidance for preventative action against diabetes

New guidance for preventative action against diabetes
2014-03-06
A team of academics from the University of Leicester has been instrumental in shaping National Institute for Health and Care Excellence (NICE) guidance that will influence medical policy towards diabetes prevention nationwide. NICE's recommendations in the form of a local government briefing, which have been developed with advice from NICE's Local Government Reference Group using feedback from council officers, councillors and directors of public health, encourage local authorities and partner organisations to use body mass index (BMI) as a signal for preventive action ...

Penn team finds a new structure in dogs' eye linked to blinding retinal diseases

2014-03-06
In humans, a tiny area in the center of the retina called the fovea is critically important to viewing fine details. Densely packed with cone photoreceptor cells, it is used while reading, driving and gazing at objects of interest. Some animals have a similar feature in their eyes, but researchers believed that among mammals the fovea was unique to primates — until now. University of Pennsylvania vision scientists report that dogs, too, have an area of their retina that strongly resembles the human fovea. What's more, this retinal region is susceptible to genetic blinding ...

Researchers gain new insights into ancient Pacific settlers' diet

Researchers gain new insights into ancient Pacific settlers diet
2014-03-06
Researchers from New Zealand's University of Otago studying 3000-year-old skeletons from the oldest known cemetery in the Pacific Islands are casting new light on the diet and lives of the enigmatic Lapita people, the likely ancestors of Polynesians. Their results—obtained from analysing stable isotope ratios of three elements in the bone collagen of 49 adults buried at the Teouma archaeological site on Vanuatu's Efate Island—suggest that its early Lapita settlers ate reef fish, marine turtles, fruit bats, free-range pigs and chickens, rather than primarily relying on ...

Atypical development in the siblings of children with autism is detectable at 12 months

2014-03-06
(SACRAMENTO, Calif.) — Atypical development can be detected as early as 12 months of age among the siblings of children with autism spectrum disorder, a study published by researchers with the UC Davis MIND Institute and UCLA has found. Published online in the Journal of the American Academy of Child and Adolescent Psychiatry, the study found that close to half of the younger siblings of children with autism spectrum disorder (ASD) develop in an atypical fashion, with 17 percent developing ASD and another 28 percent showing delays in other areas of development or behavior. ...

Study: Alzheimer's disease a much larger cause of death than reported

2014-03-05
MINNEAPOLIS – A new study suggests that Alzheimer's disease may contribute to close to as many deaths in the United States as heart disease or cancer. The research is published in the March 5, 2014, print issue of Neurology®, the medical journal of the American Academy of Neurology. Currently, Alzheimer's disease falls sixth on the list of leading causes of death in the United States according to the Centers for Disease Control and Prevention (CDC), whereas heart disease and cancer are numbers one and two, respectively. These numbers are based on what is reported on ...

Restless legs syndrome may signify bigger health problems

2014-03-05
(Boston)--A nationally-recognized sleep expert has published an editorial describing Restless Legs Syndrome (RLS) as a possible biomarker for underlying disease. The editorial appears in the March 5, 2014 issue of Neurology the medical journal of the American Academy of Neurology and was authored by Boston Medical Center neurologist Sanford H. Auerbach, MD. RLS is a disorder of the nervous system. Patients with RLS have uncomfortable sensations in their legs which lead to an overwhelming urge to move them – most often at night or whenever the patient is resting. The ...

Applying math to cancer, climate, crime and cameras

2014-03-05
Improving radiation therapies for cancer mathematically In a paper published in December in the SIAM Journal on Scientific Computing, authors Li-Tien Cheng, Bin Dong, Chunhua Men, Xun Jia, and Steve Jiang propose a method to optimize radiation therapy treatments in cancer patients. Radiation therapy is one of the primary methods used for cancer treatment, along with chemotherapy and surgery. While doses of radiation are delivered to eliminate cancerous tissue, care is taken to keep radiation within acceptable levels so as not to affect neighboring tissues and organs. ...

3-D changes in DNA may lead to a genetic form of Lou Gehrig's disease

3-D changes in DNA may lead to a genetic form of Lou Gehrigs disease
2014-03-05
New findings reveal how a mutation, a change in the genetic code that causes neurodegeneration, alters the shape of DNA, making cells more vulnerable to stress and more likely to die. The particular mutation, in the C9orf72 gene, is the most common cause for amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), and frontotemporal degeneration (FTD), the second most common type of dementia in people under 65. This research by Jiou Wang, Ph.D., and his colleagues at Johns Hopkins University (JHU) was published in Nature and was partially funded by ...

Look back at US soybeans shows genetic improvement behind increased yields

2014-03-05
URBANA, Ill. – Soybean improvement through plant breeding has been critical over the years for the success of the crop. In a new study that traces the genetic changes in varieties over the last 80 years of soybean breeding, researchers concluded that increases in yield gains and an increased rate of gains over the years are largely due to the continual release of greater-yielding cultivars by breeders. "This research in some ways looks back and informs us how soybean varieties have changed. It's useful to document these traits and changes," said Brian Diers, a University ...

Fertility prospects following ectopic pregnancy

2014-03-05
WINSTON-SALEM, N.C. – March 5, 2014 – Preserving a fallopian tube following an ectopic pregnancy seems like it would favor a woman's fertility prospects, right? A new study from Wake Forest Baptist Medical Center looked at pregnancy outcomes in regards to the two surgical treatments for ectopic pregnancy -- salpingectomy, in which the affected fallopian tube is removed, or salpingotomy, in which the tube is preserved. The aim of the study, said co-author Tamer Yalcinkaya, M.D., a reproductive endocrinologist at Wake Forest Baptist, was to assess whether salpingotomy ...

Maize and bacteria: A 1-2 punch knocks copper out of stamp sand

Maize and bacteria: A 1-2 punch knocks copper out of stamp sand
2014-03-05
Scientists have known for years that together, bacteria and plants can remediate contaminated sites. Ramakrishna Wusirika, of Michigan Technological University, has determined that how you add bacteria to the mix can make a big difference. He has also shed light on the biochemical pathways that allow plants and bacteria to clean up some of the worst soils on the planet while increasing their fertility. Wusirika, an associate professor of biological sciences, first collected stamp sands near the village of Gay, in Michigan's Upper Peninsula. For decades, copper mining ...

NASA tests new robotic refueling technologies

NASA tests new robotic refueling technologies
2014-03-05
NASA has successfully concluded a remotely controlled test of new technologies that would empower future space robots to transfer hazardous oxidizer – a type of propellant – into the tanks of satellites in space today. Concurrently on the ground, NASA is incorporating results from this test and the Robotic Refueling Mission on the International Space Station to prepare for an upcoming ground-based test of a full-sized robotic servicer system that will perform tasks on a mock satellite client. Collectively, these efforts are part of an ongoing and aggressive technology ...

OU study suggests non-uniform climate warming global

2014-03-05
A recent University of Oklahoma study of five decades of satellite data, model simulations and in situ observations suggests the impact of seasonal diurnal or daily warming varies between global regions affecting many ecosystem functions and services, such as food production, carbon sequestration and climate regulation. The effects of non-uniform climate warming on terrestrial ecosystems is a key challenge in carbon cycle research and for those making future predictions. Jianyang Xia, a research associate in the OU College of Arts and Sciences, says the impact of non-uniform ...

A small step toward discovering habitable earths

A small step toward discovering habitable earths
2014-03-05
University of Arizona researchers snapped images of a planet outside our solar system with an Earth-based telescope using essentially the same type of imaging sensor found in digital cameras instead of an infrared detector. Although the technology still has a very long way to go, the accomplishment takes astronomers a small step closer to what will be needed to image earth-like planets around other stars "This is an important next step in the search for exoplanets because imaging in visible light instead of infrared is what we likely have to do if we want to detect planets ...

Researchers find potential target for drug to treat allergic asthma

2014-03-05
COLUMBUS, Ohio – An enzyme that helps maintain immune system function by "throwing away" a specific protein has a vital role in controlling symptoms of allergic asthma, new research in mice suggests. The finding suggests that this enzyme, called Cbl-b, could be a target for drugs used to treat allergic asthma and other autoimmune disorders. This new study, led by Ohio State University researchers, is the first to link Cbl-b to allergic asthma in an animal model. The findings parallel results from a 2012 Yale study in humans, which suggested that a mutation in the ...

Pumping iron: A hydrogel actuator with mussel tone

Pumping iron: A hydrogel actuator with mussel tone
2014-03-05
Protein from a small, tasty mollusk inspired Michigan Technological University's Bruce P. Lee to invent a new type of hydrogel actuator. Hydrogels are soft networks of polymers with high water content, like jello. Because of their soft, gentle texture, they have the potential to interact safely with living tissues and have applications in a number of medical areas, including tissue engineering. Lee, an assistant professor of biomedical engineering, wanted to make a hydrogel that wouldn't just sit there. "Hydrogels that can change shape on command could be used to deliver ...

Going viral to target tumors

2014-03-05
March 5, 2014, New York, NY– A Ludwig Cancer Research study suggests that the clinical efficacy of checkpoint blockade, a powerful new strategy to harness the immune response to treat cancers, might be dramatically improved if combined with oncolytic virotherapy, an investigational intervention that employs viruses to destroy tumors. Published today in the journal Science Translational Medicine, the study evaluated a combination therapy in which the Newcastle disease virus (NDV), a bird virus not ordinarily harmful to humans, is injected directly into one of two melanoma ...

Biomarkers of cell death in Alzheimer's reverse course after symptom onset

Biomarkers of cell death in Alzheimers reverse course after symptom onset
2014-03-05
Three promising biomarkers being studied to detect Alzheimer's disease in its early stages appear to undergo a surprising shift as patients develop symptoms of dementia, researchers at Washington University School of Medicine in St. Louis report. Scientists use the biomarkers to assess brain changes linked to the disease in research volunteers. The levels of markers of neuronal injury increase in the spinal fluid for a decade or more before the onset of dementia, but in a new twist, the research shows for the first time that they later reverse course, decreasing as symptoms ...

An inventive new way to profile immune cells in blood

An inventive new way to profile immune cells in blood
2014-03-05
ROVIDENCE, R.I. [Brown University] — When a person becomes sick or is exposed to an unwelcome substance, the body mobilizes specific proportions of different immune cells in the blood. Methods of discovering and detecting those profiles are therefore useful both clinically and in research. In a new paper in the journal Genome Biology, a team of scientists describes a new and uniquely advantageous way to detect them. All the current means of counting immune cells in a blood sample require whole cells, said Karl Kelsey, professor of epidemiology at Brown and corresponding ...

Novel cancer vaccine holds promise against ovarian cancer, mesothelioma

Novel cancer vaccine holds promise against ovarian cancer, mesothelioma
2014-03-05
A novel approach to cancer immunotherapy – strategies designed to induce the immune system to attack cancer cells – may provide a new and cost-effective weapon against some of the most deadly tumors, including ovarian cancer and mesothelioma. Investigators from the Massachusetts General Hospital (MGH) Vaccine and Immunotherapy Center report in the Journal of Hematology & Oncology that a protein engineered to combine a molecule targeting a tumor-cell-surface antigen with another protein that stimulates several immune functions prolonged survival in animal models of both ...

Hungry for 'likes': Frequent Facebook use linked to eating disorder risk, study finds

2014-03-05
TALLAHASSEE, Fla. — Frequent Facebook users might be sharing more than party pictures, vacation videos and shameless selfies — they also share a greater risk of eating disorders, according to a new study led by Florida State University researchers. Psychology Professor Pamela K. Keel studied 960 college women and found that more time on Facebook was associated with higher levels of disordered eating. Women who placed greater importance on receiving comments and "likes" on their status updates and were more likely to untag photos of themselves and compare their own photos ...

Prenatal nicotine exposure may lead to ADHD in future generations

2014-03-05
TALLAHASSEE, Fla. — Prenatal exposure to nicotine could manifest as attention deficit hyperactivity disorder in children born a generation later, according to a new study by Florida State University College of Medicine researchers. Professors Pradeep G. Bhide and Jinmin Zhu have found evidence that ADHD associated with nicotine can be passed across generations. In other words, your child's ADHD might be an environmentally induced health condition inherited from your grandmother, who may have smoked cigarettes during pregnancy a long time ago. And the fact that you never ...

A single gene, doublesex, controls wing mimicry in butterflies

A single gene, doublesex, controls wing mimicry in butterflies
2014-03-05
A single gene regulates the complex wing patterns, colors and structures required for mimicry in swallowtail butterflies, report scientists from the University of Chicago, March 5 in Nature. Surprisingly, the gene described, doublesex, is already well-known for its critical role in sexual differentiation in insects. "Conventional wisdom says that it should be multiple genes working together to control the whole wing pattern of a butterfly," said Marcus Kronforst, Neubauer Family Assistant Professor of Ecology & Evolution at the University of Chicago and senior author ...

Ultra sensitive detection of radio waves with lasers

Ultra sensitive detection of radio waves with lasers
2014-03-05
Radio waves are used for many measurements and applications, for example, in communication with mobile phones, MRI scans, scientific experiments and cosmic observations. But 'noise' in the detector of the measuring instrument limits how sensitive and precise the measurements can be. Now researchers at the Niels Bohr Institute have developed a new method where they can avoid noise by means of laser light and can therefore achieve extreme precision of measurements. The results are published in the prestigious scientific journal, Nature. 'Noise' in the detector of a measuring ...
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