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Associations of childhood, adolescence, and midlife cognitive function with DNA methylation age acceleration in midlife

Associations of childhood, adolescence, and midlife cognitive function with DNA methylation age acceleration in midlife
2024-06-25
“[...] our study brings attention to the potential influence of adolescent crystalized intelligence on age-related DNAm at older age.” BUFFALO, NY- June 25, 2024 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, “Associations of childhood, adolescence, and midlife cognitive function with DNA methylation age acceleration in midlife.” Prior studies showed increased age acceleration (AgeAccel) is associated with worse cognitive function among ...

Think you might have COVID? Wait two days to test

Think you might have COVID? Wait two days to test
2024-06-25
Peek in medicine cabinets across the U.S. and you’ll find stacks of leftover COVID-19 tests. When symptoms arise, so do questions: When should I test? How accurate is it really? And what should I do if I test positive? In a paper published June 14 in the journal Science Advances, CU Boulder researchers unveil a new mathematical model to quickly answer such questions, not only for COVID but also for emerging rapid tests for respiratory syncytial virus (RSV), the flu and other infectious diseases. One key takeaway: Advice can differ ...

Researchers develop new training technique that aims to make AI systems less socially biased

Researchers develop new training technique that aims to make AI systems less socially biased
2024-06-25
CORVALLIS, Ore. – An Oregon State University doctoral student and researchers at Adobe have created a new, cost-effective training technique for artificial intelligence systems that aims to make them less socially biased. Eric Slyman of the OSU College of Engineering and the Adobe researchers call the novel method FairDeDup, an abbreviation for fair deduplication. Deduplication means removing redundant information from the data used to train AI systems, which lowers the high computing costs of the training. Datasets gleaned from the internet often contain biases present in society, the researchers said. When those biases are codified in trained AI models, they can serve to perpetuate ...

Backward walking speed reserve assessment offers improved clinical screening for risks and decline in MS patients

2024-06-25
DETROIT — Wayne State University postdoctoral research fellows Patrick Monaghan, Ph.D., and Michael VanNostrand, Ph.D., along with Nora E. Fritz, Ph.D., PT, DPT, NCS, director of the Neuroimaging and Neurorehabilitation Lab and associate professor of physical therapy in the Department of Health Care Sciences in WSU’s Eugene Applebaum College of Pharmacy and Health Sciences, recently published a study on mobility assessments in the journal, Multiple Sclerosis and Related Disorders. The study, “Backwards walking speed reserve in persons ...

Clinical trial evaluates economic impact of changing how healthcare is delivered to older people in the emergency department

2024-06-25
The evaluation of the OPTI-MEND trial demonstrates that investing in an additional dedicated professional team to the already existing ED care increases patients’ quality of life and will save, on average per person, a staggering €6,128. Crowding in emergency departments (EDs) is a growing problem in Ireland and internationally and, coupled with long waiting times, affects healthcare outcomes and patient satisfaction. A new study from researchers at Trinity College Dublin and University of Limerick examined the economic impact of adding a specific, appropriate, and dedicated team of professionals to the care already available ...

Uncovering the drivers of a million-year-old glacial transition

2024-06-25
The climate modeling community has been particularly vexed by the glacial/interglacial cycles of the past three million years, when the Northern Hemisphere oscillated between times with and without large ice sheets. From about 1.25 million to 750,000 years ago—in the Pleistocene epoch—a change in glacial cycles called the Mid-Pleistocene Transition (MPT) occurred. During this time, glacial/interglacial cycles shifted from occurring every 41,000 years to every 100,000 years, with an increase in the amplitude and asymmetry of the cycles. Scientists are working to understand why these changes happened, considering that insolation forcing—variation ...

Surprising vortex behind new solar cell and lighting materials

Surprising vortex behind new solar cell and lighting materials
2024-06-25
Metal-halide perovskites have quickly advanced in the last decade since their discovery as a semiconductor that outshines silicon in its conversion of light into electric current.  Simulations on TACC's Frontera and Lonestar6 supercomputers have revealed surprising vortex structures in quasiparticles of electrons and atoms, called polarons, which contribute to generating electricity from sunlight. This new discovery can help scientists develop new solar cells and LED lighting. This type of lighting is hailed as eco-friendly, sustainable technology ...

Should you eat more dietary fiber? New study says it depends.

2024-06-25
ITHACA, N.Y. -- Nutritionists generally advise everyone to eat more dietary fiber, but a new Cornell University study suggests that its effects on health can vary from person to person. The findings indicate that recommendations should be tailored to each individual’s gut microbiome. The study, published in Gut Microbes, focused on resistant starch, a category of dietary fiber found in such foods as bread, cereals, green bananas, whole-grain pasta, brown rice and potatoes. The researchers identified ...

Researchers evaluate the benefit of dual therapy for children at risk for spinal muscular atrophy

2024-06-25
In a first-of-its-kind study, researchers compared the efficacy of preventative therapy for spinal muscular atrophy (SMA) between two well-matched study groups, using either gene therapy (onasemnogene abeparvovec) alone or in combination with risdiplam (oral medication) or nusinersen (intrathecal injection) administered before apparent signs of disease emerged. The study included presymptomatic infants with two or three copies of SMN2 at risk for developing SMA type 1 or 2, respectively. SMA is a devastating ...

Analysis suggests 2021 Texas abortion ban resulted in increase in infant deaths in state in year after law went into effect

2024-06-25
A study led by Johns Hopkins Bloomberg School of Public Health researchers estimates that infant deaths in Texas increased more than expected in the year following the state’s 2021 ban on abortion in early pregnancy, especially among infants with congenital anomalies.  The Texas law prohibiting abortions after a fetal heartbeat could be detected—as early as five or six weeks—went into effect September 1, 2021. At the time, the law—Senate Bill 8, or S.B. 8—was the most stringent state abortion law in the country. It did not allow exemptions for congenital ...

Large integrative medicine center implements processes to measure and understand clinical effectiveness

Large integrative medicine center implements processes to measure and understand clinical effectiveness
2024-06-25
CLEVELAND - Led by a team of researchers at University Hospitals Connor Whole Health, a new study finds that collecting paper-based patient-reported outcome (PRO) measures of pain, anxiety, and stress is feasible – and that provider, operational, and clinical-level factors impact successful completion more so than patient factors. Patients often seek integrative health and medicine (IHM) modalities such as acupuncture, chiropractic, and massage in the outpatient setting, most commonly for concerns of pain, anxiety, and stress. In contrast to ...

Empathetic children may have poorer health in the face of interparental conflict

2024-06-25
UNIVERSITY PARK, Pa. — Children who report being more empathetic are more likely to show signs of poorer health in the face of more interparental conflict than less empathetic children, according to a new study led by researchers in the Penn State College of Health and Human Development. The study, led by Hannah Schreier, associate professor of biobehavioral health and co-funded faculty member in the Social Science Research Institute, was recently published in the journal Brain, Behavior, and Immunity. “For children this age, 7 to 9 years old, the family home and parents are important, so observing conflict ...

Marsquakes may help reveal whether liquid water exists underground on red planet

2024-06-25
UNIVERSITY PARK, Pa. — If liquid water exists today on Mars, it may be too deep underground to detect with traditional methods used on Earth. But listening to earthquakes that occur on Mars — or marsquakes — could offer a new tool in the search, according to a team led by Penn State scientists. When quakes rumble and move through aquifers deep underground, they produce electromagnetic signals. The researchers reported in the journal JGR Planets how those signals, if also produced on Mars, could identify water miles under the surface. The study may lay the groundwork for future analyses of data from Mars missions, according to ...

Unexpected diversity of light-sensing proteins goes beyond vision in frogs

Unexpected diversity of light-sensing proteins goes beyond vision in frogs
2024-06-25
UNIVERSITY PARK, Pa. — Frogs have maintained a surprising diversity of light-sensing proteins over evolutionary time, according to a new study led by a Penn State researcher. Light-sensing proteins, called opsins, enable vision in sighted animals, and are responsible for many more biological functions like regulating circadian rhythms. The researchers explored the evolution of nonvisual opsins in frogs, finding that most modern species examined in this study retained a shocking number of these proteins. The findings were published in the June issue of the journal Molecular ...

University of Houston strengthens commitment to clean energy with key partnerships

University of Houston strengthens commitment to clean energy with key partnerships
2024-06-25
HOUSTON, June 25, 2024 - The University of Houston, the energy university with multiple energy-focused research centers, last week signed two memorandums of understanding with industry partners Promethean Energy and Endeavor Management. The agreements formalize the partnership to address the challenges of repurposing offshore infrastructure for clean energy use. Both companies will work closely with UH Energy, the University’s interdisciplinary energy initiative, and members of UH’s Repurposing Offshore Infrastructure for Clean ...

UT Arlington prioritizes undergraduate research to ensure student success

UT Arlington prioritizes undergraduate research to ensure student success
2024-06-25
Studies have shown that undergraduate students who participate in research activities under the guidance of a faculty member or mentor are more likely to finish college. That’s one of the reasons why The University of Texas at Arlington has tripled its investment in specific undergraduate research opportunities. “Engaging students in original scholarship is time-intensive and expensive, but the outcomes are overwhelmingly positive, leading to more student success and an increase in the number of students interested in pursuing graduate school, including medical school,” said Kayunta Johnson-Winters, interim director of undergraduate research at UTA and an associate ...

Researchers identify a novel biomarker linked to renal cancer recurrence

2024-06-25
Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence. The findings were published in JCO Precision Oncology. Kidney cancer accounts for about 3-5% of all cancers; clear cell renal cancer makes up about 75% of all kinds of kidney cancers. Currently, treatment for clear cell renal cancer is determined based on the size and grade of the tumor and stage of overall disease. But this “one-size-fits-all” approach isn’t always precise. “We ...

Farmland weeds help to combat pests

Farmland weeds help to combat pests
2024-06-25
Leaving some weeds between crops can help to combat pests on agricultural land, according to a new study carried out by the University of Bonn. This step has particularly positive effects in combination with other measures: the cultivation of different types of crops and planting strips of wildflowers. The results have now been published in the Journal of Pest Science. Intercropping, i.e. planting different types of crops on the same field has a number of benefits: The crops have different requirements and the crops face less competition than when grown in monocultures. This means that they make better use of the water and nutrients ...

The American Ornithological Society (AOS) announces its 2024 award winners for achievements in ornithological research by early-career professionals

The American Ornithological Society (AOS) announces its 2024 award winners for achievements in ornithological research by early-career professionals
2024-06-25
CHICAGO — June 25, 2024 — The American Ornithological Society (AOS) annually bestows research awards honoring early-career researchers for their ornithological research. This year’s early-career research awardees represent outstanding contributions to the scientific study and conservation of birds. The 2024 recipients will accept their awards at the 2024 AOS annual meeting (AOS 2024) this October in Estes Park, Colorado. The AOS’s James G. Cooper Early Professional Award and the Ned K. Johnson Early Investigator Award are presented annually to recognize outstanding and promising ...

From sunspots to traffic jams: Explaining real-world patterns scoops major maths prize for Surrey professor

2024-06-25
A Surrey mathematician is the first ever UK-based winner of a prestigious international prize for his work to better understand patterns which contribute to a diverse range of phenomena, including stop-and-go traffic jams, weather fronts, sunspots and crime hotspots. The T Brooke Benjamin Prize is awarded every two years by the Society for Industrial and Applied Mathematics (SIAM) – the world's largest applied mathematics society – for outstanding ...

Orchid awakening: Unveiling the hormonal choreography behind flower development

Orchid awakening: Unveiling the hormonal choreography behind flower development
2024-06-25
A cutting-edge study has uncovered the complex hormonal and genetic interactions that dictate the seasonal flowering cycle of Cymbidium sinense, the Chinese orchid. This research sheds light on the enigmatic mechanisms of floral bud dormancy and its subsequent activation, offering new perspectives on the control of flowering times in plants. Flower development in plants is a complex process influenced by various intrinsic and extrinsic factors. Hormones like gibberellin (GA) and abscisic acid (ABA) play pivotal roles in regulating this process. In many orchids, including the Chinese Cymbidium, flower bud dormancy ...

EMBO Gold Medal awarded to Elvan Böke

2024-06-25
EMBO awards the EMBO Gold Medal 2024 to Elvan Böke, group leader at the Centre for Genomic Regulation (CRG) in Barcelona, Spain. The award recognizes researchers under the age of 40 for outstanding contributions to the life sciences in Europe. The awardee receives a gold medal and a bursary of 10,000 euros.  Early-stage oocytes are exposed to biological and environmental factors for decades, which can make them susceptible to cumulative damage. At the same time, the growth phases associated with oocyte maturation ...

Battling anthracnose: Unearthing the plant's arsenal against pathogenic fungi

Battling anthracnose: Unearthing the plants arsenal against pathogenic fungi
2024-06-25
A pivotal study has shed light on the intricate mechanisms of nonhost resistance (NHR) in plants, a critical defense against a broad spectrum of pathogens. By identifying and characterizing four novel core effectors from the pathogen Colletotrichum fructicola, researchers have unveiled key players in the plant Nicotiana benthamiana's immune response. This discovery is set to transform approaches to plant disease management, offering a pathway to bolster crops against devastating fungal infections. Plant diseases caused by pathogens like Colletotrichum ...

Robots face the future

Robots face the future
2024-06-25
Researchers have found a way to bind engineered skin tissue to the complex forms of humanoid robots. This brings with it potential benefits to robotic platforms such as increased mobility, self-healing abilities, embedded sensing capabilities and an increasingly lifelike appearance. Taking inspiration from human skin ligaments, the team, led by Professor Shoji Takeuchi of the University of Tokyo, included special perforations in a robot face, which helped a layer of skin take hold. Their research could be useful in the cosmetics industry and to help train plastic surgeons. Takeuchi is a pioneer in the field of biohybrid ...

Physical, sexual, and intimate partner violence among transgender and gender-diverse individuals

2024-06-25
About The Study: In this survey study of adults in California, results showed that transgender and gender-diverse individuals, especially transgender men, are at higher risk of experiencing all forms of violence relative to cisgender women. Results highlight the need for gender-affirming violence prevention and intervention services as well as policies that protect transgender and gender-diverse individuals from discriminatory violence. Corresponding Author: To contact the corresponding author, Sabrina ...
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