Life cycles of some insects adapt well to a changing climate. Others, not so much.
2025-01-31
As insect populations decrease worldwide in what some have called an "insect apocalypse," biologists are desperate to determine how the six-legged creatures are responding to a warming world and to predict the long-term winners and losers.
A new study of Colorado grasshoppers shows that, while the answers are complicated, biologists have much of the knowledge they need to make these predictions and prepare for the consequences.
The findings, published Jan. 30 in the journal PLOS Biology, come thanks to the serendipitous ...
With generative AI, MIT chemists quickly calculate 3D genomic structures
2025-01-31
CAMBRIDGE, MA -- Every cell in your body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different from a skin cell, are partly determined by the three-dimensional structure of the genetic material, which controls the accessibility of each gene.
MIT chemists have now come up with a new way to determine those 3D genome structures, using generative artificial intelligence. Their technique can predict thousands of structures in just minutes, making it much speedier than existing experimental methods for analyzing the structures.
Using this technique, researchers could more ...
The gut-brain connection in Alzheimer’s unveiled with X-rays
2025-01-31
Scientists led by the Institute of Nanotechnology in Italy, in collaboration with the ESRF, the European Synchrotron in Grenoble, France, have discovered how X-ray micro- and nano- tomography can provide clues on the processes that link the gut neurons with those in the brain and may trigger Alzheimer’s. The results are published in Science Advances.
Alzheimer’s disease, the most common type of dementia, is a neurodegenerative disorder characterized by brain alteration including synaptic loss, chronic inflammation and neuronal cell death.
In recent years, scientists have found evidence that the gut and the brain communicate through the neurons placed in ...
NIH-funded clinical trial will evaluate new dengue therapeutic
2025-01-31
A clinical trial supported by the National Institutes of Health (NIH) is testing an experimental treatment designed to help people suffering the effects of dengue, a mosquito-borne viral disease. The study is supported by NIH’s National Institute of Allergy and Infectious Diseases (NIAID), and will involve exposing adult volunteers to a weakened strain of dengue virus that causes a mild form of the disease and administering an investigational therapeutic at various doses to assess its safety and ability to lessen symptoms.
Dengue ...
Sound is a primary issue in the lives of skateboarders, study shows
2025-01-31
Sound plays a significant and often poignant part of skateboarders’ relationship with their sport, a new study shows.
Skateboarders develop the skill to tune into the noise of urban surfaces. They both hear and feel noise and this means images and videos alone are a poor insight into the sport. They use sound to verify the success of their manoeuvres, judge the veracity and capacity of surfaces for use and as a social cue. For some the sensory overload of skateboarding is therapeutic and it helps them connect with others skating nearby.
But ...
Watch what you eat: NFL game advertisements promote foods high in fat, sodium
2025-01-31
ST. LOUIS – Research from Saint Louis University (SLU) and the University of Nevada, Reno School of Medicine finds that some of the most-watched ads promote the worst food options for adults with chronic health conditions.
The findings published online on Jan. 30 in JAMA Network analyzed advertisements transmitted during televised NFL games in the U.S. to assess the nutritional content by serving.
The study found that store-bought foods and quick-service restaurants advertised during NFL games, the most watched sporting events in the U.S., ...
Red Dress Collection Concert hosted by Sharon Stone kicks off American Heart Month
2025-01-31
DALLAS, Jan. 31, 2025 — Academy Award-nominated actress and host Sharon Stone, alongside musical guests Sara Bareilles and Suki Waterhouse, headlined a roster of powerful players in music, entertainment, fashion and philanthropy to officially mark the start of American Heart Month at the Red Dress Collection® Concert on Thursday, January 30. The fashion-forward, musical celebration in New York City serves as the national marquee event for the American Heart Association’s Go Red for Women® movement, celebrating progress made while calling for a renewed commitment to the fight against cardiovascular disease, the number one killer ...
One of the largest studies on preterm birth finds a maternal biomarker test significantly reduces neonatal morbidities and improves neonatal outcomes
2025-01-31
UNDER EMBARGO UNTIL: Jan. 31, 2025, 10:15 a.m. MST
Media Contact: Karen Addis, APR, karen@addispr.com, +1 (301) 787-2394
One of the Largest Studies on Preterm Birth Finds a Maternal Biomarker Test Significantly Reduces Neonatal Morbidities and Improves Neonatal Outcomes
Denver, Colo. ― Preterm birth ― defined as delivery before the 37th week of pregnancy — is one of the leading causes of infant deaths in the United States. Babies born prematurely are also at an increased risk of ...
One of the largest studies of its kind finds early intervention with iron delivered intravenously during pregnancy is a safe and effective treatment for anemia
2025-01-31
Denver, Colo. ― Anemia during pregnancy is a common occurrence and often due to iron deficiency. It is a global public health problem, affecting an estimated 37 percent of pregnant individuals, according to the World Health Organization. Iron deficiency anemia is associated with increased rates of pregnancy-related problems, such as going into labor prematurely, hemorrhaging and, in some cases, even death. For the infant, maternal iron deficiency also can have long-term implications on their overall health and development.
Current obstetric guidelines recommend ...
New Case Western Reserve University study identifies key protein’s role in psoriasis
2025-01-31
CLEVELAND—Psoriasis, a painful and uncomfortable inflammatory skin condition that affects millions worldwide, flares up from the activity of disease- and infection-protecting immune cells.
In a new study, researchers at Case Western Reserve University School of Medicine have determined that a protein called NF-kB c-Rel can intensify the condition’s symptoms when activated by signals from the body’s immune system. Understanding how “c-Rel” affects skin inflammation could lead to new treatments, they said.
The study, published recently in eBioMedicine, examined how ...
First-ever ethics checklist for portable MRI brain researchers
2025-01-31
MINNEAPOLIS/ST. PAUL (01/31/2025) — Portable MRI (pMRI) technologies are rapidly transforming the landscape of neuroscience research, allowing neuroscientists to acquire brain data in community settings outside the hospital for the first time. But as neuroscientists increase access to MRI technology and move their research from a lab environment to broad community settings, they face novel ethical, legal, and societal issues (ELSI).
To prepare neuroscientists to address these challenges, an interdisciplinary team of scientists, ethicists, and legal experts, supported by an NIH BRAIN Initiative grant, analyzed the issues. The team released the first-ever checklist ...
Addressing 3D effects of clouds for significant improvements of climate models
2025-01-31
Leipzig. Over the next few years, climate researchers from Germany aim to achieve a breakthrough in the radiative properties of clouds by describing the corresponding processes not just one-dimensionally, as has been the case up to now, but three-dimensionally in future. Capturing clouds and radiation in 3D is seen as an important step towards undistorted remote sensing of the atmosphere and improved modelling of climate and weather. The new research group of the German Research Foundation (DFG) brings together experts in atmospheric radiation, high-resolution ...
Gut microbes may mediate the link between drinking sugary beverages and diabetes risk
2025-01-31
It is well known that consuming sugary drinks increases the risk of diabetes, but the mechanism behind this relationship is unclear. Now, in a paper publishing January 31 in the Cell Press journal Cell Metabolism, researchers show that metabolites produced by gut microbes might play a role. In a long-term cohort of US Hispanic/Latino adults, the researchers identified differences in the gut microbiota and blood metabolites of individuals with a high intake of sugar-sweetened beverages. The altered metabolite profile ...
Ribosomes team up in difficult situations, new technology shows
2025-01-31
Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The researchers discovered that ribosomes help each other when encountering difficulties, a process they refer to as ‘ribosome cooperativity’. This technique and the findings, published in Cell, provide insights into how proteins are made and offer other researchers a tool to better study mRNA translation.
Our DNA contains genetic information essential for ...
Mortality trends among adults ages 25-44 in the US
2025-01-31
About The Study: This cross-sectional study found that compared with trends from the early 2000s, early adult (ages 25-44) mortality in the U.S. has risen substantially in 2 stages: 2011 to 2019 and 2020 to 2023. Although mortality rates decreased after the core pandemic years, excess mortality remained higher than expected based on pre-pandemic levels. The largest portion of 2023 excess mortality was driven by drug poisoning, but many other external and natural causes exceeded what prior trends would have projected.
Corresponding Author: To contact the corresponding author, Elizabeth Wrigley-Field, PhD, email ewf@umn.edu.
To access the embargoed study: Visit our ...
Discontinuation and reinitiation of dual-labeled GLP-1 receptor agonists among us adults with overweight or obesity
2025-01-31
About The Study: In this cohort study, most patients with overweight or obesity discontinued glucagon-like peptide-1 receptor agonist (GLP-1 RA) therapy within 1 year, but those without type 2 diabetes had higher discontinuation rates and lower reinitiation rates. Inequities in access and adherence to effective treatments have the potential to exacerbate disparities in obesity.
Corresponding Author: To contact the corresponding author, Ezekiel J. Emanuel, MD, PhD, email zemanuel@upenn.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.57349)
Editor’s ...
Ultraprocessed food consumption and obesity development in Canadian children
2025-01-31
About The Study: High ultraprocessed food consumption during early childhood was associated with obesity development, primarily in males in this cohort study of Canadian children. These findings can inform targeted public health initiatives for early childhood centers and caregiver education programs to reduce ultraprocessed food intake and prevent obesity.
Corresponding Author: To contact the corresponding author, Kozeta Miliku, MD, PhD, email kozeta.miliku@utoronto.ca.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2024.57341)
Editor’s Note: Please see the ...
Experts publish framework for global adoption of digital health in medical education
2025-01-31
A group of 211 international experts from 79 countries has today published a new framework to facilitate the design, development and implementation of digital health curricula in medical education worldwide.
Published in JAMA Network Open, the Digital Health Competencies in Medical Education (DECODE) framework is designed to help medical institutions better equip future physicians for the ongoing digital transformation in healthcare.
The framework is already beginning to be adopted across the globe, including in the UK where it has influenced ...
Canadian preschoolers get nearly half of daily calories from ultra-processed foods: University of Toronto study
2025-01-31
Researchers at the University of Toronto are sounding the alarm about the high consumption of ultra-processed foods among preschool-aged children in Canada and its association with obesity development.
“We saw that ultra-processed foods contributed to almost half of a child’s total daily energy intake,” says Kozeta Miliku, assistant professor of nutritional sciences at U of T’s Temerty Faculty of Medicine.
The findings, published today in JAMA Network Open, are the first to describe sex-driven differences in the effects of ultra-processed food on obesity risk among Canadian children, with stronger ...
City of Hope scientists identify mechanism for self-repair of the thymus, a crucial component of the immune system
2025-01-31
LOS ANGELES — A team of international researchers led by scientists at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States, with its National Medical Center in Los Angeles ranked among the nation’s top 5 cancer centers by U.S. News & World Report, have demonstrated a way to boost thymic function after damage in preclinical studies. The team’s study results, published today in the journal Immunity, outline their discovery of a specific type ...
New study reveals how reduced rainfall threatens plant diversity
2025-01-31
Predicting and mitigating the effects of climate change while preserving biodiversity is a top priority for both scientists and policymakers. As climate change intensifies, leading to more frequent and severe droughts, understanding the impact on natural ecosystems has become increasingly important. One of the main challenges is forecasting changes in species richness due to shifts in precipitation patterns. While it’s established that, on a broad geographic scale, regions with more water generally support greater plant diversity, results vary at ...
New study reveals optimized in vitro fertilization techniques to boost coral restoration efforts in the Caribbean
2025-01-31
A recent study published in PeerJ Life and Environment unveils refined techniques for in vitro fertilization (IVF) in four key Caribbean coral species, offering a crucial advancement in coral reef restoration efforts. Researchers from SECORE International, the CARMABI Foundation, and the University of Amsterdam have developed new insights into the optimal conditions for coral breeding, which could significantly enhance larval production and bolster declining coral populations.
Study Focus
The study examined four broadcast-spawning ...
No evidence that maternal sickness during pregnancy causes autism
2025-01-31
While many studies have reported a link between a mother’s health condition during pregnancy and her child’s risk of autism, a new study shows that nearly all of these “associations” can otherwise be explained by factors such as genetics, exposure to pollution, and access to healthcare.
Led by researchers at NYU Langone Health, the study revealed that, of the few conditions truly associated with autism, all were actually complications with the fetus — leading the authors to believe ...
Healthy gut bacteria that feed on sugar analyzed for the first time
2025-01-31
A microbe found in the lower part of the gut that is associated with good health has been comprehensively analysed and found to have a focused diet breaking down sugars locked away in mucus..
The new study, published in Nature Microbiology today (Friday 31 January) is a complete systematic analysis of how the human colonic beneficial microbe, Akkermansia muciniphila (AM) feeds on types of sugar found in the mucus secreted in the digestive system. The study focused on 66 enzymes that the AM microbe uses to break down mucus that is an essential part of the mucus layer that lines the human ...
240-year-old drug could save UK National Health Service £100 million a year treating common heart rhythm disorder
2025-01-31
A 240-year-old drug called digoxin could save the National Health Service (NHS) at least £100 million each year when treating older patients with atrial fibrillation and heart failure. This was compared to usual treatment with a beta-blocker according to a new study from the University of Birmingham, the city where digoxin was first used in 1785.
In a paper published in the journal Heart, researchers conducted an economic analysis on a clinical trial called RATE-AF to look at the differences between two widely used drugs for older patients with a common heart rhythm disorder called atrial fibrillation (AF) and symptoms ...
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