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Pancreatic cancer research receives $8m philanthropic funding boost

Pancreatic cancer research receives $8m philanthropic funding boost
2024-05-21
An exceptional $8 million, 10-year philanthropic investment will spearhead new treatments for pancreatic cancer and create a new dedicated research centre at WEHI. The centre, to be established thanks to an investment by Australian business leader and WEHI President Jane Hemstritch AO, aims to help close the significant survival gap between pancreatic cancer and other cancers. The Hemstritch Centre of Excellence for Pancreatic Cancer Research will provide a leading team of scientists and clinicians with long-term funding to ask big research questions. They aim to make major ...

'Hunting for treasures' with AI: Astronomers detect rare neutral atomic-carbon absorbers with deep neural network

Hunting for treasures with AI: Astronomers detect rare neutral atomic-carbon absorbers with deep neural network
2024-05-21
Recently, an international team led by Prof. GE Jian from the Shanghai Astronomical Observatory of the Chinese Academy of Sciences conducted a search for rare weak signals in quasar spectral data released by the Sloan Digital Sky Survey III (SDSS-III) program using deep learning neural networks. By introducing a new method to explore galaxy formation and evolution, the team showcased the potential of artificial intelligence (AI) in identifying rare weak signals in astronomical big data. This study was published ...

Researchers develop perovskite X-ray detector for medical imaging

Researchers develop perovskite X-ray detector for medical imaging
2024-05-21
Technology (SIAT) of the Chinese Academy of Sciences, in collaboration with researchers at Central China Normal University, have developed a high-performance perovskite X-ray complementary metal-oxide-semiconductor (CMOS) detector for medical imaging. The study was published in Nature Communications on Feb. 21. X-ray imaging is vital for the diagnosis and treatment of cardiovascular and cancer diseases. Direct-conversion X-ray detectors made of semiconductor materials exhibit superior spatial and temporal resolution at lower radiation doses compared to indirect-conversion detectors made of scintillator materials. However, the currently available semiconductor ...

Rice chemist Gustavo Scuseria wins 2024 Schrödinger Medal

Rice chemist Gustavo Scuseria wins 2024 Schrödinger Medal
2024-05-21
By Jade Boyd Special to Rice News Pioneering Rice University chemist Gustavo Scuseria has won the 2024 Schrödinger Medal from the World Association of Theoretical and Computational Chemists. Awarded annually to a single recipient, the medal recognizes an outstanding body of work in theoretical and computational chemistry. Scuseria has pioneered quantum computational methods that are widely used to study the complex quantum states and electronic properties of a wide range of molecules and materials. In awarding the medal, ...

Monitoring the recovery process accurately with a medical needle and thread!

Monitoring the recovery process accurately with a medical needle and thread!
2024-05-21
□ DGIST (President Kunwoo Lee) announced on the 16th (Tue) that a research team led by Professor Jaehong Lee of the Department of Robotics and Mechanical Electronics has developed a new human implantable, wireless, health monitoring electronic suture system through joint research with a team from Yonsei University and Korea University. The developed wireless electronic suture can be easily applied in the medical field and is expected to be used in various orthopedic fields, such as patient-customized rehabilitation. □ ...

One essential step for a germ cell, one giant leap for the future of reproductive medicine

One essential step for a germ cell, one giant leap for the future of reproductive medicine
2024-05-21
KYOTO, Japan – May 20, 2024 Infertility affects approximately 1 in 6 people in their lifetime worldwide according to the World Health Organization (WHO). Infertility —as defined by the American Society for Reproductive Medicine (ASRM)— is a disease, condition, or status characterized by “the inability to achieve a successful pregnancy based on a patient’s medical, sexual, and reproductive history, age, physical findings, diagnostic testing, or any combination of those factors” or requiring medical intervention such as the use of mature donor gametes “to achieve a successful pregnancy ...

Powering wearable devices with high-performing carbon nanotube yarns

Powering wearable devices with high-performing carbon nanotube yarns
2024-05-21
Ikoma, Japan – With the growth of the Internet of Things, sustainable solution for powering wireless sensors and devices are considered important. Thermoelectric generators, for example, which have the ability to convert waste heat into electricity can offer a sustainable solution. Researchers around the world have been working on such solutions. A research team, led by Masakazu Nakamura from Nara Institute of Science and Technology (NAIST), Japan has also been working on flexible wearable thermoelectric generators that produce electricity from body heat by sewing nanomaterial called carbon nanotubes (CNTs) into fabric. Effective ...

Genes provide hope for the survival of Arabia’s last big cat

2024-05-21
The authors of a major study on the Critically Endangered Arabian leopard say that the release of captive bred animals carefully selected for their genes can make a significant contribution to the successful recovery of the dwindling wild population and avert the prospect of extinction.   An international collaboration led by scientists from the Durrell Institute of Conservation and Ecology (DICE) at the University of Kent, University of East Anglia (UEA), University College London (UCL), Nottingham-Trent University (NTU) and the Diwan of Royal Court in Oman, surveyed the remote Dhofar mountain range of southern Oman to determine how many of Arabia’s last big cat survive.   By ...

Auburn biologists publish first work on avian migration conducted in the AU MitoMobile

Auburn biologists publish first work on avian migration conducted in the AU MitoMobile
2024-05-21
For Wendy Hood and Geoffrey Hill in Biological Sciences, Andreas Kavazis in Kinesiology, and their team, Emma Rhodes, Paulo Mesquita, and Jeff Yap, traveling the country to unlock the mystery of mitochondria in migrating aviary species has allowed them to make a significant contribution to research in an area that has not been investigated before. The first publication conducted in the AU MitoMobile van is featured in Scientific Reports, “Flexibility underlies differences in mitochondrial respiratory performance between ...

Second Phase 3 clinical trial again shows dupilumab lessens disease in COPD patients with type 2 inflammation

Second Phase 3 clinical trial again shows dupilumab lessens disease in COPD patients with type 2 inflammation
2024-05-20
BIRMINGHAM, Ala. – Chronic obstructive pulmonary disease patients with type 2 inflammation may soon gain access to a new drug — dupilumab — that showed rapid and sustained improvements in patients in a pivotal Phase 3 clinical trial, researchers report in the New England Journal of Medicine. This monoclonal antibody is the first biologic shown to improve clinical outcomes in COPD. The data supporting the use of dupilumab in COPD will be reviewed by the United States Food and Drug Administration in June. The disease improvements — as measured by a significantly ...

Autoimmune disease not associated with monoclonal gammopathy

2024-05-20
Embargoed for release until 5:00 p.m. ET on Monday 20 May 2024     Annals of Internal Medicine Tip Sheet      @Annalsofim     Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.     ----------------------------     1. ...

Purdue-led fishing expedition nets new pupfish family member in New Mexico

Purdue-led fishing expedition nets new pupfish family member in New Mexico
2024-05-20
Purdue-led fishing expedition nets new pupfish family member in New Mexico Genetic drift, not natural selection, identified as main factor driving speciation WEST LAFAYETTE, Ind. Scientists have identified a new member on the genetic family tree of an endangered pupfish native to south-central New Mexico. “We went into this thinking that there was one species of conservation concern,” said J. Andrew DeWoody, professor of genetics in Purdue University’s Department of Forestry and Natural Resources. “The preponderance of evidence ...

Yoga and meditation-induced altered states of consciousness are common in the general population

2024-05-20
BOSTON--Yoga, mindfulness, meditation, breathwork, and other practices are gaining in popularity due to their potential to improve health and well-being. The effects of these practices are mostly positive and occasionally transformational, yet they are known to sometimes be associated with challenging altered states of consciousness. New research by a team including investigators from Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, reveals that altered states of consciousness associated with meditation practice are far more common than expected. Although many people reported positive outcomes, that were sometimes even considered ...

UCF researcher is developing algorithms to further space, sea exploration

2024-05-20
Cislunar space, which stretches from the Earth to just beyond the moon’s orbit, is about to become heavily trafficked over the next 10 years. With NASA’s planned Artemis missions and other countries joining in the cislunar space race, there’s an interest in observing, tracking and predicting the orbit of objects like asteroids and satellites so they don’t collide with spacecraft. But the process of detecting and observing space objects, known as space domain awareness (SDA), faces challenges with the extensive volume of cislunar space. “Cislunar space is vast,” says Tarek Elgohary, an associate professor ...

Illuminating neuro-vascular dynamics throughout the body: 3D-printed implants and bioluminescence duet shed light on brain–spinal interactions

Illuminating neuro-vascular dynamics throughout the body: 3D-printed implants and bioluminescence duet shed light on brain–spinal interactions
2024-05-20
A sensory process such as pain is no ordinary phenomenon—it’s a symphony of neural and vascular interactions orchestrated by the brain and spinal cord. Attempting to dissect this symphony by focusing on a single region is like trying to understand a complex melody by listening to just one instrument. It’s incomplete, potentially misleading, and may result in erroneous conclusions. Enter the Carney Institute’s team of visionaries. Their mission? To develop tools that allow unprecedented observation of neural and vascular activity within the brain and spinal cord. They tackled two critical fronts: imaging hardware and bioluminescent (BL) molecular tools. Innovative ...

Studies show linked biological pathways driving skin inflammation

2024-05-20
A certain biological pathway, a set of linked reactions in the body, drives the inflammation seen in the skin disease psoriasis, a new study finds. The work could lead to improved therapies for all inflammatory skin diseases, including atopic and allergic dermatitis and a type of boil called hidradenitis suppurativa, say the study authors. Inflammation is the body’s natural response to irritation and infection, but when out of control, it can lead to the reddish, flaky, itchy lesions that come with these skin diseases. Led by researchers at NYU Langone Health, the new study found that the interleukin-17 (IL-17) pathway, ...

Fowler awarded 2023 NASA Planetary Science Early Career Award

Fowler awarded 2023 NASA Planetary Science Early Career Award
2024-05-20
Research Assistant Professor Christopher Fowler received the NASA 2023 Planetary Science Early Career Award for his project “Bringing Planetary Science to West Virginia”. The award is based on demonstrated leadership, involvement in the planetary science community, and potential for future impact.    The resources provided by the NASA Planetary Science Early Career Award will allow Fowler and team to undertake research-related activities that are not always possible within the scope of more “traditional” ...

Anticancer potential of CLK kinase inhibitors 1C8 and GPS167 via EMT and antiviral immune response

Anticancer potential of CLK kinase inhibitors 1C8 and GPS167 via EMT and antiviral immune response
2024-05-20
“[...] we have characterized a pair of compounds that impact multiple processes that are relevant to cancer cell proliferation but also, and possibly more importantly, to metastasis [...].” BUFFALO, NY- May 20, 2024 – A new research paper was published in Oncotarget's Volume 15 on May 16, 2024, entitled, “The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response.” The diheteroarylamide-based compound 1C8 and the aminothiazole carboxamide-related compound GPS167 inhibit the CLK kinases, and affect ...

Aging contributes to 2024 Systems Aging Gordon Research Conference

Aging contributes to 2024 Systems Aging Gordon Research Conference
2024-05-20
Aging is contributing at the 2024 Systems Aging Gordon Research Conference in Barcelona, Spain, from June 2–7. BUFFALO, NY- May 20, 2024 – Aging is a contributor at the 2024 Systems Aging Gordon Research Conference (GRC) on “Systems Modeling, Aging Biomarkers, and Longevity Interventions” — taking place from June 2–7, 2024, in Castelldefels, Barcelona, Spain. “The conference will present recent advances in systemic rejuvenation, multi-omics approaches, applications ...

Pioneering research study makes significant contributions toward addressing the shortage of suitable knee meniscus and TMJ disc replacements

2024-05-20
The shortage of suitable donor meniscus grafts from the knee and temporomandibular joint (TMJ) impedes treatments for millions of patients. Vitrification offers a promising solution by transitioning these tissues into a vitreous state at cryogenic temperatures, protecting them from ice crystal damage using high concentrations of cryoprotectant agents (CPAs). However, vitrification's success is hindered for larger tissues (>3 mL) due to challenges in CPA penetration. Dense avascular meniscus tissues require extended CPA exposure for adequate penetration; however, ...

By listening, scientists learn how a protein folds

By listening, scientists learn how a protein folds
2024-05-20
CHAMPAIGN, Ill. —  By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein. Their report, in the Proceedings of the National Academy of Sciences, offers an unprecedented view of the sequence of hydrogen-bonding events that occur when a protein morphs from an unfolded to a folded state. See video: Protein Sonification “A protein must fold properly to become an enzyme or signaling molecule or whatever its function may be — all the many things that proteins do in our bodies,” said University of Illinois ...

Nano drug accelerates diabetic wound healing in mice

Nano drug accelerates diabetic wound healing in mice
2024-05-20
New York, NY [May 20, 2024]—Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown to target problem-causing cells and reduce swelling and harmful molecules in mouse models of damaged skin. Details on their findings were published in the May 20 online issue of the Proceedings of the National Academy of Sciences (PNAS). Diabetic wounds, often resistant to conventional treatments, ...

UC Irvine-led team uncovers ‘vigorous melting’ at Antarctica’s Thwaites Glacier

UC Irvine-led team uncovers ‘vigorous melting’ at Antarctica’s Thwaites Glacier
2024-05-20
Irvine, Calif., May 20, 2024 — A team of glaciologists led by researchers at the University of California, Irvine used high-resolution satellite radar data to find evidence of the intrusion of warm, high-pressure seawater many kilometers beneath the grounded ice of West Antarctica’s Thwaites Glacier. In a study published today in Proceedings of the National Academy of Sciences, the UC Irvine-led team said that widespread contact between ocean water and the glacier – a process that is replicated throughout Antarctica and in Greenland – causes “vigorous melting” and may require a reassessment of ...

Warm seawater speeding up melting of ‘Doomsday Glacier,’ scientists warn

2024-05-20
EMBARGOED UNTIL 15:00 EDT MONDAY, MAY 20, 2024 For the first time, there is visible evidence showing that warm seawater is pumping underneath Antarctica’s Thwaites Glacier—ominously nicknamed the Doomsday Glacier. An international team of scientists—including a researcher from the University of Waterloo—observed it using satellite imagery and warns that it could accelerate catastrophic sea level rise in 10 to 20 years.  The intrusion of seawater causes the ice to continuously lift off the land and settle back down again. Ice melts intensely when it first touches seawater, ...

Can coal mines be tapped for rare earth elements?

Can coal mines be tapped for rare earth elements?
2024-05-20
Deposits of designated critical minerals needed to transition the world’s energy systems away from fossil fuels may, ironically enough, be co-located with coal deposits that have been mined to produce the fossil fuel most implicated in climate change. Now, research led by the University of Utah has documented elevated concentrations of a key subset of critical minerals, known as rare earth elements, or REEs, in active mines rimming the Uinta coal belt of Colorado and Utah. These findings open the possibility that these mines could see a secondary resource stream in the form of metals used in renewable energy and numerous other high-tech ...
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