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Study examines reasons for delay, denial of new drugs by FDA

2014-01-22
Study examines reasons for delay, denial of new drugs by FDA Several potentially preventable deficiencies, including failure to select optimal drug doses and suitable outcome measures for a study, accounted for significant delays in the approval of new drugs ...

Biomarkers in blood show potential as early detection method of pancreatic cancer

2014-01-22
Biomarkers in blood show potential as early detection method of pancreatic cancer Researchers have identified diagnostic microRNA panels in whole blood that had the ability to distinguish, to some degree, patients with and without pancreatic cancer, according ...

Many CV devices approved by process that often does not require new clinical data

2014-01-22
Many CV devices approved by process that often does not require new clinical data Many cardiac implantable electronic device models currently in use were approved via a Food and Drug Administration review process in which the models were assumed safe and effective ...

Mediterranean diet associated with lower risk of peripheral artery disease

2014-01-22
Mediterranean diet associated with lower risk of peripheral artery disease A multicenter study that previously reported a reduction in heart attack and stroke with a Mediterranean diet supplemented with extra-virgin olive oil or with nuts now also reports a ...

Deaths higher for heart attack patients at night and weekends

2014-01-22
Deaths higher for heart attack patients at night and weekends Research: Off-hour presentation and outcomes in patients with acute myocardial infarction: systematic review and meta-analysis Mortality is higher, and emergency treatment takes longer, for ...

Long term exposure to air pollution linked to coronary events

2014-01-22
Long term exposure to air pollution linked to coronary events Association persists at levels of exposure below current European limits Long term exposure to particulate matter in outdoor air is strongly linked to heart attacks and angina, and this association ...

Losing a family member in childhood associated with psychotic illness

2014-01-22
Losing a family member in childhood associated with psychotic illness Highest risk seen in children who experience suicide in close family members Experiencing a family death in childhood is associated with a small but significant increase in risk of psychosis, ...

Fast eye movements: A possible indicator of more impulsive decision-making

2014-01-22
Fast eye movements: A possible indicator of more impulsive decision-making Using a simple study of eye movements, Johns Hopkins scientists report evidence that people who are less patient tend to move their eyes with greater speed. The findings, the researchers say, ...

Most high-risk cardiac devices in use today approved as modifications to previously-approved devices

2014-01-22
Most high-risk cardiac devices in use today approved as modifications to previously-approved devices Device 'supplement' applications are generally not accompanied by new clinical testing, with implications for patient safety Boston – The Food and Drug Administration ...

New sequencing tools give up close look at yeast evolution

2014-01-22
New sequencing tools give up close look at yeast evolution Highlights in this week's Molecular Biology and Evolution The baker's yeast Saccharomyces cerevisiae has been associated with human activities for thousands of ...

All FDA drug approvals not created equal

2014-01-22
All FDA drug approvals not created equal Many patients and physicians assume that the safety and effectiveness of newly approved drugs is well understood by the federal Food and Drug Administration (FDA) —but a new study by researchers at Yale School of Medicine shows ...

Hedges and edges help pigeons learn their way around

2014-01-22
Hedges and edges help pigeons learn their way around A study has found that homing pigeons' ability to remember routes depends on the complexity of the landscape below, with hedges and boundaries between urban and rural areas ...

Large amounts of folic acid shown to promote growth of breast cancer in rats

2014-01-22
Large amounts of folic acid shown to promote growth of breast cancer in rats Role of folate in development, progression of breast cancer highly controversial TORONTO, Jan. 21, 2014---Folic acid supplements at levels consumed by breast cancer patients and survivors ...

Cochrane Review of dihydroartemisinin-piperaquine

2014-01-22
Cochrane Review of dihydroartemisinin-piperaquine Cochrane review of dihydroartemisinin-piperaquine for treating uncomplicated malaria 'Dihydroartemisinin-piperaquine is more effective than artemether-lumefantrine, and has fewer side effects than artesunate-mefloquine' ...

Researchers identify innate channel that protects against pain

2014-01-22
Researchers identify innate channel that protects against pain Scientists have identified a channel present in many pain detecting sensory neurons that acts as a 'brake', limiting spontaneous pain. It is hoped that the new research, published today ...

Study: Electric drive vehicles have little impact on US pollutant emissions

2014-01-22
Study: Electric drive vehicles have little impact on US pollutant emissions A new study from North Carolina State University indicates that even a sharp increase in the use of electric drive passenger vehicles (EDVs) by 2050 would not significantly reduce ...

Study: 'Icy' technique improves robotic kidney transplants

2014-01-22
Study: 'Icy' technique improves robotic kidney transplants DETROIT – A collaboration of surgeons at Henry Ford Hospital and Medanta Hospital in India successfully transplanted kidneys into 50 recipients using an innovative robot-assisted procedure in which ...

More diseases from air pollution uncovered by improved data material

2014-01-22
More diseases from air pollution uncovered by improved data material At rest, we breathe approx. 12-15 times per minute, and for each inhalation we change approx. one litre of air. Depending on the activity level, this makes up a daily quantity in the order of twenty cubic metres ...

Understanding the functioning of a new type of solar cell

2014-01-21
Understanding the functioning of a new type of solar cell Photovoltaic energy conversion offers one of the best means for the future of renewable energy in the world. The efficiency of solar cells depends heavily upon the light-absorbing materials ...

DNA barcodes change our view on how nature is structured

2014-01-21
DNA barcodes change our view on how nature is structured How you seek is what you find To understand how feeding interactions are structured, researchers from Finland and Canada chose to focus on one of the simplest food webs on Earth: the moths and butterflies ...

Quality control of mitochondria as a defense against disease

2014-01-21
Quality control of mitochondria as a defense against disease HEIDELBERG, 20 January 2014 – Scientists from the Montreal Neurological Institute and Hospital in Canada have discovered that two genes linked to hereditary Parkinson's disease are ...

Ultra-thin tool heating for injection molding

2014-01-21
Ultra-thin tool heating for injection molding If you have ever tried to make waffles then you are bound to be familiar with the following problem: You only get good waffles if the iron is heated to the correct temperature. The same principle ...

Hydrocephalus: Sensors monitor cerebral pressure

2014-01-21
Hydrocephalus: Sensors monitor cerebral pressure Urinary incontinence, a shuffling gait, and deteriorating reasoning skills are all indicators pointing to a Parkinsonian or Alzheimer type disease. An equally plausible explanation is hydrocephalus, ...

Micropredators dictate occurrence of deadly amphibian disease

2014-01-21
Micropredators dictate occurrence of deadly amphibian disease A new study raises hope to successfully fight the chytrid amphibian pathogen This news release is available in German. Leipzig: An international team of researchers has made ...

Bio-inspired robotic device could aid ankle-foot rehabilitation, CMU researcher says

2014-01-21
Bio-inspired robotic device could aid ankle-foot rehabilitation, CMU researcher says Unlike rigid exoskeletons, soft wearable robot enables natural motions PITTSBURGH—A soft, wearable device that mimics the muscles, tendons and ligaments of the lower leg could ...
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