JCI early table of contents for Nov. 1, 2013 Liver tropism is key for B cell deletion immunotherapy Antibodies against the B cell surface protein CD20 have been used successfully to treat B cell-mediated autoimmune diseases and lymphomas. Antibody binding ...

Liver tropism is key for B cell deletion immunotherapy Antibodies against the B cell surface protein CD20 have been used successfully to treat B cell-mediated autoimmune diseases and lymphomas. Antibody binding receptors, called Fc receptors, on other ...

Dysfunctional chemokine receptor promotes candidiasis Candida albicans is one of the leading causes of hospital-acquired infections in immune compromised patients. The risk of both developing candidiasis and the clinical outcome of infection is variable ...

Home visits lessen emergency care for infants Nurse home visits lead to dramatic savings in emergency care DURHAM, N.C. -- Home visits from a nurse are a proven, but expensive, way to help newborns get a good start in life. New research from Duke University suggests ...

New study: Rising temperatures challenge Salt Lake City's water supply In an example of the challenges water-strapped Western cities will face in a warming world, new research shows that every degree Fahrenheit of warming in the Salt Lake City region ...

Children of lower socioeconomic status grow up more susceptible to catching colds, Carnegie Mellon researchers find Researchers at Carnegie Mellon University have found an association between lower socioeconomic status during childhood and adolescence and the length ...

Patients with heart failure need specialist care New research from Karolinska Institutet in Sweden shows that patients with heart failure have high mortality and often are undertreated. According to a study, published in the scientific periodical JACC, many more ...

New IOF review provides guidance on fracture prevention in cancer-associated bone disease International Osteoporosis Foundation Working Group outlines guidelines, treatment options and care pathways to help prevent osteoporosis and fractures in cancer ...

Nationwide disparities of deaths reported to coroners A LEADING detective turned university researcher has discovered huge nationwide disparities in the numbers of deaths reported to coroners. It could mean that in some areas, inquests into unnaturaldeaths ...

Double-pronged attack could treat common children's cancer A dual-pronged strategy using two experimental cancer drugs together could successfully treat a childhood cancer by inhibiting tumour growth and blocking off the escape routes it uses to become resistant ...

Sugar intake is not directly related to liver disease Despite current beliefs, sugar intake is not directly associated with nonalcoholic fatty liver disease, according to a new study in Gastroenterology, the official journal of the American Gastroenterological ...

LSUHSC simulation or team training improves performance & patient safety New Orleans, LA – A study conducted by an inter-professional team of LSU Health Sciences Center New Orleans faculty found that simulation-based operating room team training ...

Neuroscientists determine how treatment for anxiety disorders silences fear neurons Study in mice may aid in the development of more effective treatments for anxiety disorders BOSTON (October 31, 2013, 12 noon ET) — Excessive fear can ...

Pitt treats gum disease by bringing needed immune cells to inflamed tissue PITTSBURGH, Nov. 1, 2013 – The red, swollen and painful gums and bone destruction of periodontal disease could be effectively treated by beckoning the ...

GenSeq: Updated nomenclature for genetic sequences to solve taxonomic determination issues An improved and expanded nomenclature for genetic sequences is introduced that corresponds with a ranking of the reliability of the taxonomic identification of the source specimens. ...

Problem of gender differences on physics assessments remains unsolved The mystery of why women consistently score lower than men on common assessments of conceptual understanding of physics remains poorly understood In a new synthesis of past work, researchers found ...

Designing an acoustic diode Novel design for a device that would transmit sound in 1-way may lead to brighter, clearer ultrasound images and improve diagnosis and therapy WASHINGTON, D.C. Nov. 1, 2013 -- Most people know about ultrasound through its role ...

Study explains how a job-market system lands couples in the same city Since World War II, women have entered the American workforce in greater numbers than ever before. For married couples, this presents a wrinkle, since it can be hard for both partners ...

NASA satellite catches a wide-eyed Typhoon Krosa Typhoon Krosa became wide-eyed in imagery from NASA's Aqua satellite as the storm moved past the Philippines and into the South China Sea. Krosa re-strengthened after it passed over the northern Philippines and its ...

2 satellites see new Eastern Pacific tropical depression form The eighteenth tropical depression of the Eastern Pacific Ocean hurricane season formed early on the first day of November and is expected to become a tropical storm. NASA's TRMM satellite observed moderate ...

A new model for organ repair Kidney repair may not require stem cells Harvard Stem Cell Institute (HSCI) researchers have a new model for how the kidney repairs itself, a model that adds to a growing body of evidence that mature cells are far more plastic than had previously ...

Congenital blindness results in lower thermal pain thresholds Absence of vision from birth leads to a permanent state of pain hypersensitivity, reports PAIN® Philadelphia, November 1, 2013 – An international team of scientists investigated whether congenitally ...

NASA begins airborne campaign to map Greenland ice sheet summer melt For the first time, a NASA airborne campaign will measure changes in the height of the Greenland Ice Sheet and surrounding Arctic sea ice produced by a single season of summer melt. NASA's ...

Kessler researchers find aerobic exercise benefits memory in persons with multiple sclerosis Collaborative study reveals novel finding that aerobic exercise results in increased hippocampal volume, increased connectivity and improved memory in persons with MS West ...

Segregation in American schools still problematic, despite best efforts MADISON, Wis. — As American schools struggle with issues of race, diversity and achievement, a new study in the American Sociological Review has split the difference in the ongoing discussion of ...