Eligibility for aspirin for primary prevention in men increases when cancer mortality benefit added
2013-06-06
CHAPEL HILL, N.C. - While aspirin has been shown to be effective in preventing heart attacks in men, it also increases the risk of gastrointestinal bleeding and possibly stroke, even at low doses. As such, national guidelines suggest that aspirin be used for prevention only in men at higher risk for cardiovascular events, so that the benefits of aspirin are greater than its adverse effects.
Recent data suggest that aspirin may also be effective for reducing cancer deaths. Would the possible combined health benefits of reducing heart attacks and cancer outweigh the risks ...
Unusual antibodies in cows suggest new ways to make therapies for people
2013-06-06
LA JOLLA, CA – June 6, 2013 – Humans have been raising cows for their meat, hides and milk for millennia. Now it appears that the cow immune system also has something to offer. A new study led by scientists from The Scripps Research Institute (TSRI) focusing on an extraordinary family of cow antibodies points to new ways to make human medicines.
"These antibodies' structure and their mechanism for creating diversity haven't been seen before in other animals' antibodies," said Vaughn V. Smider, assistant professor of cell and molecular biology at TSRI and principal investigator ...
Conservatives more likely than liberals to identify mixed-race individuals as Black, NYU study finds
2013-06-06
Conservatives are more likely than liberals to identify mixed-race individuals as Black, according to a series of new studies by researchers at New York University. Their findings, which appear in the Journal of Experimental Social Psychology, suggest that there is a link between political ideology and racial categorization.
"A person's race is often thought to be clear-cut and fixed," explains Amy Krosch, a doctoral student in New York University's Department of Psychology and the lead author of the paper. "However, our research suggests that the perception of a person ...
Big multiple sclerosis breakthrough
2013-06-06
CHICAGO --- A phase 1 clinical trial for the first treatment to reset the immune system of multiple sclerosis (MS) patients showed the therapy was safe and dramatically reduced patients' immune systems' reactivity to myelin by 50 to 75 percent, according to new Northwestern Medicine research.
In MS, the immune system attacks and destroys myelin, the insulating layer that forms around nerves in the spinal cord, brain and optic nerve. When the insulation is destroyed, electrical signals can't be effectively conducted, resulting in symptoms that range from mild limb numbness ...
Discovery of oldest primate skeleton, ancestor of humans and apes
2013-06-06
Grenoble, 5 June 2013: An international team of researchers has announced the discovery of the world's oldest known fossil primate skeleton representing a previously unknown genus and species named Archicebus achilles. The fossil was unearthed from an ancient lake bed in central China's Hubei Province, near the course of the modern Yangtze River. In addition to being the oldest known example of an early primate skeleton, the new fossil is crucial in elucidating a pivotal event in primate and human evolution—the evolutionary divergence that led to modern monkeys, apes and ...
Discovery of oldest primate skeleton helps chart early evolution of humans, apes
2013-06-06
An international team of researchers has announced the discovery of the world's oldest known fossil primate skeleton, an animal that lived about 55 million years ago and was even smaller than today's smallest primate, the pygmy mouse lemur. The new specimen, named Archicebus achilles, was unearthed from an ancient lake bed in central China's Hubei Province, near the course of the modern Yangtze River. In addition to being the oldest known example of an early primate skeleton, this almost complete new fossil is crucial for illuminating a pivotal event in primate and human ...
Nutrition during first 1,000 days of life crucial for childhood and economic development
2013-06-06
A new Lancet series on maternal and childhood nutrition finds that over 3 million children die every year of malnutrition—accounting for nearly half of all child deaths under 5. Along with state-of-the-art global estimates on the long-term burden of malnutrition, the series presents a new framework for prevention and treatment that considers underlying factors, such as food security, social conditions, resources, and governance. Professor Robert Black, Department of International Health at the Johns Hopkins Bloomberg School of Public Health, led the consortium of experts ...
Fear learning studies point to a potential new treatment for PTSD
2013-06-06
A team of researchers from Emory, University of Miami and Scripps Research Institute has identified a compound that can reduce PTSD-like symptoms in mice after they are exposed to stress. The discovery could lead to a treatment given to people shortly after a traumatic event, aimed at preventing possible PTSD (post-traumatic stress disorder).
The results are scheduled for publication Wednesday in the journal Science Translational Medicine.
The team's research meshes with recent studies – one looking at military personnel injured in Iraq -- hinting that morphine administration ...
Scientists discover oldest primate skeleton
2013-06-06
DeKalb, Ill. – An international team of paleontologists that includes Northern Illinois University anthropologist Dan Gebo is announcing the discovery of a nearly complete, articulated skeleton of a new tiny, tree-dwelling primate dating back 55 million years.
The Eocene Epoch fossil was recovered from Hubei Province in central China.
"This is the oldest primate skeleton of this quality and completeness ever discovered and one of the most primitive primate fossils ever documented," Gebo said. "The origin of primates sets the first milestone for all primate lineages, ...
Researchers announce discovery of oldest-known fossil primate skeleton
2013-06-06
Pittsburgh, Pennsylvania…An international team of researchers has announced the discovery of the world's oldest known fossil primate skeleton representing a previously unknown genus and species named Archicebus achilles. The fossil was unearthed from an ancient lake bed in central China's Hubei Province, near the course of the modern Yangtze River. In addition to being the oldest known example of an early primate skeleton, the new fossil is crucial for illuminating a pivotal event in primate and human evolution—the evolutionary divergence between the lineage leading to ...
Electronic stimulation therapy for obstructive sleep apnea found safe, effective
2013-06-06
A clinical study has found that electronic stimulation therapy to reduce obstructive sleep apnea (OSA) is safe and effective.
The Stimulation Therapy for Apnea Reduction (The STAR Trial) evaluated an implantable electronic stimulation device called Inspire™ Upper Airway Stimulation (UAS) therapy designed to deliver mild stimulation to the main nerve of the tongue (hypoglossal nerve) on each breathing cycle during sleep. The stimulation is intended to restore tone to key airway muscles and prevent airway collapse.
Patients control when the Inspire therapy is turned ...
Researchers reveal malaria's deadly grip
2013-06-06
Researchers at the University of Copenhagen, in collaboration with Seattle Biomedical Research Institute, the University of Oxford, NIMR Tanzania and Retrogenix LTD, have identified how malaria parasites growing inside red blood cells stick to the sides of blood vessels in severe cases of malaria.
The discovery may advance the development of vaccines or drugs to combat severe malaria by stopping the parasites attaching to blood vessels. The results are now published in the scientific journal Nature.
Though researchers have known for over a century that red blood cells ...
Short-term therapy given by para-professionals reduces symptoms among rape survivors in DRC
2013-06-06
Survivors of sexual violence have long gone without treatment and suffered debilitating symptoms of depression, anxiety and post-traumatic stress disorder.
But a randomized controlled study of 405 rape survivors in eastern Democratic Republic of Congo proves that short-term therapy delivered by para-professionals is effective at reducing mental health symptoms, according to a study released in the New England Journal of Medicine.
The study, "Controlled Trial of Psychotherapy for Congolese Survivors of Sexual Violence," provided 154 women cognitive processing therapy ...
Nontoxic cancer therapy proves effective against metastatic cancer
2013-06-06
Tampa, FL (June 5, 2013) -- A combination of nontoxic dietary and hyperbaric oxygen therapies effectively increased survival time in a mouse model of aggressive metastatic cancer, a research team from the Hyperbaric Biomedical Research Laboratory at the University of South Florida has found.
The study, "The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer," was published online today in PLOS ONE.
Led by Dominic D'Agostino, PhD, principal investigator in the Department of Molecular Pharmacology and Physiology at the ...
UCLA scientists isolate new population of pluripotent stem cells in fat removed during liposuction
2013-06-06
Researchers from the UCLA Department of Obstetrics and Gynecology have isolated a new population of primitive, stress-resistant human pluripotent stem cells easily derived from fat tissue that are able to differentiate into virtually every cell type in the human body without genetic modification.
The cells, called Multi-lineage Stress-Enduring (Muse-AT) stem cells from fat, or adipose, tissue, were discovered by "scientific accident" when a piece of equipment failed in the lab, killing all the stem cells in the experiment except for the Muse-AT cells. The research team ...
Irish chronicles reveal links between cold weather and volcanic eruptions
2013-06-06
Medieval chronicles have given an international group of researchers a glimpse into the past to assess how historical volcanic eruptions affected the weather in Ireland up to 1500 years ago.
By critically assessing over 40,000 written entries in the Irish Annals and comparing them with measurements taken from ice cores, the researchers successfully linked the climatic aftermath of volcanic eruptions to extreme cold weather events in Ireland over a 1200-year period from 431 to 1649.
Their study, which has been published today, 6 June, in IOP Publishing's journal Environmental ...
First observation of spin Hall effect in a quantum gas is step toward 'atomtronics'
2013-06-06
Researchers at the National Institute of Standards and Technology (NIST) have reported* the first observation of the "spin Hall effect" in a Bose-Einstein condensate (BEC), a cloud of ultracold atoms acting as a single quantum object. As one consequence, they made the atoms, which spin like a child's top, skew to one side or the other, by an amount dependent on the spin direction. Besides offering new insight into the quantum mechanical world, they say the phenomenon is a step toward applications in "atomtronics"—the use of ultracold atoms as circuit components.
The spin ...
Genetic mutation inherited from father's side linked to early puberty
2013-06-06
Boston, MA – Reaching puberty at an unusually early age can have adverse effects on social behavior and psychological development, as well as physical effects, including short stature, and lifelong health risks, such as diabetes, breast cancer and heart disease. Researchers at Brigham and Women's Hospital (BWH), in a multi-institutional collaboration with Boston Children's Hospital, the Broad Institute, and the University of Sao Paulo, Brazil, have identified that a genetic mutation leads to a type of premature puberty, known as central precocious puberty. Central precocious ...
Drug prevents post-traumatic stress-like symptoms in mice
2013-06-06
When injected into mice immediately following a traumatic event, a new drug prevents the animals from developing memory problems and increased anxiety that are indicative of post-traumatic stress disorder (PTSD).
Howard Hughes Medical Institute scientists utilized mouse studies to suggest that a receptor called Oprl1 is altered in mice with PTSD-like symptoms. They then worked with a group at the Scripps Research Institute who had previously developed the Oprl1-targeted drug to examine its effects on fear memory modulation.
The group has also shown that in humans, ...
University of Maryland School of Medicine finds gut bacteria play key role in vaccination
2013-06-06
Baltimore, Md. — June 5, 2013. The bacteria that live in the human gut may play an important role in immune response to vaccines and infection by wild-type enteric organisms, according to two recent studies resulting from a collaborative effort between the University of Maryland School of Medicine Institute for Genome Sciences and the Center for Vaccine Development. The first study, published online in PLOS ONE, http://umm.gd/13E3OHl, examines the impact of an oral typhoid vaccination on the microbiota, or populations of bacteria, in the human gut. The second study, also ...
Noble way to low-cost fuel cells, halogenated graphene may replace expensive platinum
2013-06-06
Ulsan, South Korea– The research team of Ulsan National Institute of Science and Technology (UNIST), Case Western Reserve University and University of North Texas have paved a new way for affordable commercialization of fuel cells with efficient metal-free electrocatalysts using edge-halogenated graphene nanoplatelets.
Fuel cell technology has come a long way since the early days in the Apollo space program. Certainly the idea of running a car on pure hydrogen is an exciting prospect as the only emissions will be pure water.
But how much will you be willing to pay ...
Ancient trapped water explains Earth's first ice age
2013-06-06
Tiny bubbles of water found in quartz grains in Australia may hold the key to understanding what caused the Earth's first ice age, say scientists.
The Anglo-French study, published in the journal Nature, analysed the amount of ancient atmospheric argon gas (Ar) isotopes dissolved in the bubbles and found levels were very different to those in the air we breathe today.
The researchers say their findings help explain why Earth didn't suffer its first ice age until 2.5 billion years ago, despite the Sun's rays being weaker during the early years of our planet's formation.
"The ...
New study rebuts increase in willingness to cooperate from intuitive thinking
2013-06-06
The first study drew the conclusion that people cooperate more if they are forced to make decisions when pressed for time. The research group (Rand et al.) let the test subjects make decisions under pressure on social dilemmas. They found that the decisions made at the time were more oriented towards cooperation. The conclusion was that decisions under pressure that build on intuition promote cooperation. It has gotten a lot of attention and aroused a great deal of discussion.
But it is not true, argues a group of researchers at several universities, including Linköping ...
Firefighting robot paints 3-D thermal imaging picture for rescuers
2013-06-06
Engineers in the Coordinated Robotics Lab at the University of California, San Diego, have developed new image processing techniques for rapid exploration and characterization of structural fires by small Segway-like robotic vehicles.
A sophisticated on-board software system takes the thermal data recorded by the robot's small infrared camera and maps it onto a 3D scene constructed from the images taken by a pair of stereo RGB cameras.
This allows small mobile robotic vehicles to create a virtual reality picture that includes a 3D map and temperature data that can ...
Bacillus thuringiensis Cry4B toxin kills Anopheles gambiae, a principal vector of malaria
2013-06-06
Researchers at The University of Texas at Dallas (UTD), led by Dr. Lee Bulla, have characterized a protein produced by the soil bacterium Bacillus thuringiensis subsp. israelensis (Bti), which is highly toxic against Anopheles gambiae, the principal mosquito vector of malaria. The protein toxin, which has been known for a number of years, is produced in a complex of other protein toxins, called Cry toxins, which also have mosquitocidal activity against other species of mosquito. The novelty of the research done by the UTD scientists is that they differentially fractionated ...
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