A novel screening method makes it easier to diagnose and treat children with autism
2013-07-24
Researchers have developed a new screening method to diagnose autism, which unlike current methods does not rely on subjective criteria. These results are published in a series of studies in the open-access journal Frontiers in Neuroscience.
The studies, funded by a US$ 650,000 grant from the National Science Foundation, were led by Elizabeth Torres, a computational neuroscientist, and Dimitri Metaxas, a computer scientist, both at Rutgers University, in collaboration with Jorge V. Jose, a theoretical physicist and computational neuroscientist from Indiana University. ...
Stanford scientists unable to find evidence of 'embryonic-like' cells in marrow of adult mice
2013-07-24
STANFORD, Calif. — Research on human embryonic stem cells has been a political and religious lightning rod for more than a decade.
The cells long have been believed to be the only naturally occurring pluripotent cells. (Under the right conditions, pluripotent cells can become any other cell in the body.) But some people object to the fact that the embryo is destroyed during their isolation. Induced pluripotent stem cells, created by experimentally manipulating an adult cell such as a skin or nerve cell, are much more ethically palatable. But many researchers feel it is ...
Neural simulations hint at the origin of brain waves
2013-07-24
For almost a century, scientists have been studying brain waves to learn about mental health and the way we think. Yet the way billions of interconnected neurons work together to produce brain waves remains unknown. Now, scientists from EPFL's Blue Brain Project in Switzerland, at the core of the European Human Brain Project, and the Allen Institute for Brain Science in the United States, show in the July 24th edition of the journal Neuron how a complex computer model is providing a new tool to solve the mystery.
The brain is composed of many different types of neurons, ...
Coastal Antarctic permafrost melting faster than expected
2013-07-24
For the first time, scientists have documented an acceleration in the melt rate of permafrost, or ground ice, in a section of Antarctica where the ice had been considered stable. The melt rates are comparable with the Arctic, where accelerated melting of permafrost has become a regularly recurring phenomenon, and the change could offer a preview of melting permafrost in other parts of a warming Antarctic continent.
Tracking data from Garwood Valley in the McMurdo Dry Valleys region of Antarctica, Joseph Levy, a research associate at The University of Texas at Austin's ...
Want to stick with your diet? Better have someone hide the chocolate
2013-07-24
If you are trying to lose weight or save for the future, new research suggests avoiding temptation may increase your chances of success compared to relying on willpower alone. The study on self-control by researchers from the Universities of Cambridge and Dusseldorf was published today in the journal Neuron.
The researchers compared the effectiveness of willpower versus voluntarily restricting access to temptations, called 'precommitment'. (Examples of precommitment include avoiding purchasing unhealthy food and putting money in savings accounts with hefty withdrawal ...
New study shows inbreeding in winter flounder in Long Island's bays
2013-07-24
STONY BROOK, NY, July 24, 2013–Research conducted in six bays of Long Island, NY, and led by scientists from the School of Marine and Atmospheric Sciences at Stony Brook University (SBU) showed that local populations of winter flounder are inbred, which is a situation that is not usually considered in marine fisheries management. The scientists also determined that the effective number of breeders in each bay was below 500 fish, suggesting that the spawning populations of this historically common fish are now relatively small in the area.
"Severe inbreeding and small ...
Cognitive performance is better in girls whose walk to school lasts more than 15 minutes
2013-07-24
Cognitive performance of adolescent girls who walk to school is better than that of girls who travel by bus or car. Moreover, cognitive performance is also better in girls who take more than 15 minutes than in those who live closer and have a shorter walk to school.
These are some of the conclusions of a study published in Archives of Pediatrics & Adolescent Medicine. The results come from findings of the nationwide AVENA (Food and Assessment of the NutritionalStatus of Spanish Adolescents) study, in which the University of Granada has participated together with the Autonomous ...
Trust in physician eases talks about medical expenses
2013-07-24
Strong relationships with physicians, particularly those that are long standing, are likely to increase patients' openness to talk about health care costs when decisions are being made about their treatment options. According to a new study1 by Marion Danis from the National Institutes of Health Clinical Center2 in the US, and colleagues, rushed visits with insufficient time to talk about important issues can undermine efforts to bring sensitive topics like costs into the doctor-patient relationship and can be counterproductive. The work appears online in the Journal of ...
New stem cell gene therapy gives hope to prevent inherited neurological disease
2013-07-24
Scientists from The University of Manchester have used stem cell gene therapy to treat a fatal genetic brain disease in mice for the first time.
The method was used to treat Sanfilippo – a fatal inherited condition which causes progressive dementia in children – but could also benefit several neurological, genetic diseases.
Researchers behind the study, published in the journal Molecular Therapy this month, are now hoping to bring a treatment to trial in patients within two years.
Sanfilippo, a currently untreatable mucopolysaccharide (MPS) disease, affects one in 89,000 ...
Study investigates extraordinary trout with tolerance to heavily polluted water
2013-07-24
New research from the University of Exeter and King's College London has shown how a population of brown trout can survive in the contaminated waters of the River Hayle in Cornwall where metal concentrations are so high they would be lethal to fish from unpolluted sites. The team believe this is due to changes in the expression of their genes. The research was funded by NERC and the Salmon and Trout Association.
The researchers compared the trout living in the River Hayle with a population living in a relatively clean site in the River Teign. The results showed that the ...
Does the dangerous new Middle East coronavirus have an African origin?
2013-07-24
The MERS-coronavirus is regarded as a dangerous novel pathogen: Almost 50 people have died from infection with the virus since it was first discovered in 2012. To date all cases are connected with the Arabian peninsula. Scientists from the University Bonn (Germany) and South Africa have now detected a virus in the faeces of a South African bat that is genetically more closely related to MERS-CoV than any other known virus. The scientists therefore believe that African bats may play a role in the evolution of MERS-CoV predecessor viruses. Their results have just been published ...
Nature: Watching molecule movements in live cells
2013-07-24
This news release is available in German. The newly developed STED-RICS microscopy method records rapid movements of molecules in live samples. By combining raster image correlation spectroscopy (RICS) with STED fluorescence microscopy, researchers of Karlsruhe Institute of Technology (KIT) opened up new applications in medical research, e.g. analyzing the dynamics of cell membranes at high protein concentrations. This method is now presented in Nature Communications (doi: 10.1038/ncomms3093).
How do individual biomolecules move in live cells, tissues, or organisms? ...
How do babies learn to be wary of heights?
2013-07-24
Infants develop a fear of heights as a result of their experiences moving around their environments, according to new research published in Psychological Science, a journal of the Association for Psychological Science.
Learning to avoid cliffs, ledges, and other precipitous hazards is essential to survival and yet human infants don't show an early wariness of heights.
As soon as human babies begin to crawl and scoot, they enter a phase during which they'll go over the edge of a bed, a changing table, or even the top of a staircase. In fact, research shows that when ...
Are Christians becoming more 'green'?
2013-07-24
EAST LANSING, Mich. -- Despite the wide-held perception that Christians have become more concerned about the environment, new research finds this so-called "greening of Christianity" is not evident among the religious rank-and-file.
According to the Michigan State University-led study, Christians report lower levels of environmental concern than non-Christians and non-religious individuals. More than 75 percent of Americans are affiliated with a Christian denomination.
"The results suggest this presumed greening of Christianity has not yet translated into a significant ...
Novel gene target shows promise for bladder cancer detection and treatment
2013-07-24
Scientists from Virginia Commonwealth University Massey Cancer Center have provided evidence from preclinical experiments that a gene known as melanoma differentiation associated gene-9/syntenin (mda-9/syntenin) could be used as a therapeutic target to kill bladder cancer cells, help prevent metastasis and even be used to non-invasively diagnose the disease and monitor its progression.
The study, published in the journal Clinical Cancer Research, was a collaborative effort between Paul B. Fisher, M.Ph., Ph.D., who originally discovered the mda-9/syntenin gene, and Santanu ...
New NIST nanoscale indenter takes novel approach to measuring surface properties
2013-07-24
Researchers from the National Institute of Standards and Technology (NIST) and the University of North Carolina have demonstrated a new design for an instrument, a "instrumented nanoscale indenter," that makes sensitive measurements of the mechanical properties of thin films -- ranging from auto body coatings to microelectronic devices -- and biomaterials. The NIST instrument uses a unique technique for precisely measuring the depth of the indentation in a test surface with no contact of the surface other than the probe tip itself.*
Nanoindenter head
Indenters have a ...
Fidaxomicin: Data subsequently submitted by manufacturer prove added benefit
2013-07-24
In the commenting procedure on early benefit assessment pursuant to the German Act on the Reform of the Market for Medicinal Products (AMNOG), under certain circumstances drug manufacturers may submit to the Federal Joint Committee (G-BA) additional documents for dossiers. The Institute for Quality and Efficiency in Health Care (IQWiG) has now assessed such additional information for two studies comparing the antibiotic fidaxomicin, which is used for diarrhoea caused by Clostridium difficile infections, with vancomycin.
In contrast to the first dossier assessment, the ...
A magnetic pen for smartphones adds another level of conveniences
2013-07-24
Daejeon, Republic of Korea, July 24, 2013 – A doctoral candidate at the Korea Advanced Institute of Science and Technology (KAIST) developed a magnetically driven pen interface that works both on and around mobile devices. This interface, called the MagPen, can be used for any type of smartphones and tablet computers so long as they have magnetometers embedded in.
Advised by Professor Kwang-yun Wohn of the Graduate School of Culture Technology (GSCT) at KAIST, Sungjae Hwang, a Ph.D. student, created the MagPen in collaboration with Myung-Wook Ahn, a master's student ...
Solar system's youth gives clues to planet search
2013-07-24
Washington, D.C.—Comets and meteorites contain clues to our solar system's earliest days. But some of the findings are puzzle pieces that don't seem to fit well together. A new set of theoretical models from Carnegie's Alan Boss shows how an outburst event in the Sun's formative years could explain some of this disparate evidence. His work could have implications for the hunt for habitable planets outside of our solar system. It is published by The Astrophysical Journal.
One way to study the solar system's formative period is to look for samples of small crystalline particles ...
An evolutionary compromise for long tooth preservation
2013-07-24
This news release is available in German. Researchers at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, and the Senckenberg Research Institute in Frankfurt am Main, Germany, have conducted stress analyses on gorilla teeth of differing wear stages. Their findings show that different features of the occlusal surface antagonize tensile stresses in the tooth to tooth contact during the chewing process. They further show that tooth wear with its loss of dental tissue and the reduction of the occlusal relief decreases tensile stresses in the ...
New study reveals dangers to biological diversity from global cashmere garment industry
2013-07-24
A new study by the Wildlife Conservation Society and Snow Leopard Trust reveals a disturbing link between the cashmere trade and the decay of ecosystems that support some of the planet's most spectacular yet little-known large mammals.
The study finds that as pastoralists expand goat herds to increase profits for the cashmere trade in Western markets, wildlife icons from the Tibetan Plateau to Mongolia suffer – including endangered snow leopard, wild yak, chiru, saiga, Bactrian camel, gazelles, and other remarkable but already endangered species of remote Central Asia. ...
Pressurized virus blasts its infectious DNA into human cells
2013-07-24
The virus that causes those painful lip blisters known as cold sores has an internal pressure eight times higher than a car tire, and uses it to literally blast its infectious DNA into human cells, scientists are reporting in a new study. Discovery of the pressure-driven infection mechanism — the first in a human virus — opens the door to new treatments for viral infections, they add in a study in the Journal of the American Chemical Society.
Alex Evilevitch and colleagues point out that the viruses responsible for influenza, AIDS and other infections that affect millions ...
Dark chocolate lovers show higher tolerance for bitterness in chocolate ice cream
2013-07-24
Philadelphia, PA, July 24, 2013 – To make the inherent bitterness of cocoa in chocolate ice cream more palatable, manufacturers add high levels of fat and sugar. Yet, bitterness is an integral part of the complex flavor of chocolate. In a new study published in the August issue of the Journal of Dairy Science®, investigators report that consumers who prefer dark chocolate in solid form tolerate twice the amount of bitter ingredients in chocolate ice cream than those who prefer milk chocolate. Elimination of some added sugar and fats in chocolate ice cream may be acceptable, ...
Study explains why Africans may be more susceptible to tuberculosis
2013-07-24
PHILADELPHIA—A researcher from the Perelman School of Medicine at the University of Pennsylvania and colleagues have identified the genetic mutation in Africans with HIV that puts them at a much higher risk for tuberculosis (TB) infections.
Africans have some of the highest rates of TB in the world, and it has long been suspected that genetic susceptibility plays a role. However, establishing candidate genes across populations to gauge risk has remained a challenge.
Now, a new study, published this week in the online Early Edition of the Proceedings of the National ...
Brothers and sisters learn to build positive relationships in SIBS Program
2013-07-24
Little is known about how sibling relationships impact child and family functioning, but Penn State researchers are beginning to shed light on intervention strategies that can cultivate healthy and supportive sibling relationships.
Parents frequently rank their children's sibling rivalry and conflict as the number one problem they face in family life.
"In some other cultures, the roles of older and younger, male and female siblings are better defined, and in those more-structured family relationships, there is not much room for bullying and disrespect," said Mark Feinberg, ...
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