New family of proteins linked to major role in cancer Scientists have described a new family of proteins that appear to play a key role in cancer and might be targets for future cancer drugs. A major new study in the journal Nature sets out the structure ...

WSF RIO Declaration goes forward to UN Role of science in global sustainability to form basis of post-2015 MDGs RIO, December 2, 2013: The closing session of the 6th World Science Forum today published its closing declaration with ...

What drives aftershocks? High-resolution GPS signals provide new insights into the mechanisms of stress transfer in subduction zones On 27 February 2010 an earthquake of magnitude 8.8 struck South-Central Chile near the town of Maule. ...

Marine reserves enhance resilience to climate change A new study, led by a University of Southampton scientist, highlights the potential for fish communities in marine reserves to resist climate change impacts better than communities on fished coasts. The ...

Oregon researchers shed new light on solar water-splitting process Fundamental discovery could speed development of efficient semiconductor-catalytic junctions EUGENE, Ore. -- With the help of a new method called "dual-electrode photoelectrochemistry," University of Oregon ...

Koalas' low-pitched voice explained by unique organ VIDEO: This video shows the velar fold vibration at 10-45 Hz. Click here for more information. ...

Microplastics make marine worms sick Tiny bits of plastic trash could spell big trouble for marine life, starting with the worms, say a team of researchers from Plymouth University and the University of Exeter who report their evidence in a pair of studies in the Cell Press ...

JCI early table of contents for Dec. 2, 2013 Predicting outcome for high-dose IL-2 therapy in cancer patients One of the most potent forms of immunotherapy for patients with metastatic melanoma and renal cell carcinoma is high-dose (HD) bolus IL-2 therapy. ...

Predicting outcome for high-dose IL-2 therapy in cancer patients One of the most potent forms of immunotherapy for patients with metastatic melanoma and renal cell carcinoma is high-dose (HD) bolus IL-2 therapy. Approximately 15% of patients respond to ...

Blocking antioxidants in cancer cells reduces tumor growth in mice Many cancers have adapted to cope with high levels of immune system-produced free radicals, also referred to as reactive oxygen species, by overproducing antioxidant proteins. One of these ...

Silent RNAs express themselves in ALS disease RNA molecules, used by cells to make proteins, are generally thought to be "silent" when stowed in cytoplasmic granules. But a protein mutated in some ALS patients forms granules that permit translation of ...

First Nations adults have more than double the risk of end-stage kidney disease First Nations adults with diabetes have more than double the risk of end-stage kidney disease compared with non–First Nations adults, found a new study in CMAJ (Canadian ...

Johns Hopkins researchers show how a modified pacemaker strengthens failing hearts Findings advance opportunities for a 'pacemaker in a bottle' Johns Hopkins heart researchers are unraveling the mystery of how a modified pacemaker used to treat many patients ...

Evolution, Civil War history entwine in plant fossil with a tragic past Union Army forced freed slaves to dig canal where 120 million-year-old fossil plant was found COLLEGE PARK, Md – A fossil leaf fragment collected decades ago on a Virginia canal bank has been identified ...

Key found to restoring 'exhausted' HIV-fighting immune cells Protein could prove a promising new drug target Researchers have identified a protein that causes loss of function in immune cells combatting HIV. The scientists report in a paper appearing online Dec. 2 in ...

New evidence that 'gout' strongly runs in the family It's historically known as 'the king of diseases and the disease of kings' and was long thought to be caused by an overindulgent lifestyle, but now scientists at The University of Nottingham have confirmed ...

Researchers analyze growth potential in African bank loans In Africa, small women-owned business owners find it easier to obtain loans than their male counterparts. The reason for this distortion is that politicians and foreign aid organisations with their focus on bank ...

Congenital heart defects affects long-term developmental outcome Approximately one percent of all newborns in Switzerland are diagnosed with a congenital heart defect, roughly half of them require open heart surgery. Most children, including those with the most severe ...

New research shows obesity is an inflammatory disease New research in The FASEB Journal suggests that an abnormal amount of an inflammatory protein called PAR2 is present on abdominal fat tissues of overweight and obese humans and ...

EASAC report warns Europe on extreme weather event increase First comprehensive survey shows 60 percent rise over last 30 years of floods, droughts and storms Europe needs to plan for future probabilities of extreme weather. Heat waves, ...

Athletes and the words for actions A study investigates the role of the motor system in conceptualization Is it true, as some scientists believe, that to understand words like "spike" (in the volleyball sense) the brain has to "mentally" ...

IQWiG publishes new version of its General Methods Procedure for report production and section on meta-analyses updated / New sections on early benefit assessment The German Institute for Quality and Efficiency in Health Care (IQWiG) ...

Detailed image shows how genomes are copied For the first time, researchers at Umeå University have succeeded in showing how the DNA polymerase epsilon enzyme builds new genomes. The detailed image produced by these researchers shows how ...

The importance of standardizing drug screening studies An IRCM researcher sheds light on inconsistencies between large pharmacogenomic studies Montréal, December 2, 2013 – A bioinformatics expert at the IRCM, Benjamin Haibe-Kains, recently ...

Nanorobot for transporting drugs in the body A nanorobot is a popular term for molecules with a unique property that enables them to be programmed to carry out a specific task. In collaboration with colleagues in Italy and the USA, researchers at Aarhus University have ...