STANFORD, Calif. - Pulmonary hypertension, a deadly form of high blood pressure that develops in the lungs, may be caused by an inflammation-producing molecular pathway that damages the inner lining of blood vessels, according to a new study by researchers at the Stanford University School of Medicine. The results, which will be published Aug. 28 in Science Translational Medicine, suggest that using medications to block this pathway could lead to the first-known cure for the disease, apart from lung transplantation. The new research could also lead to a better understanding ...

The world's largest ice sheet could be more vulnerable to the effects of climate change than previously thought, according to new research from Durham University. A team from the Department of Geography used declassified spy satellite imagery to create the first long-term record of changes in the terminus of outlet glaciers – where they meet the sea – along 5,400km of the East Antarctic Ice Sheet's coastline. The imagery covered almost half a century from 1963 to 2012. Using measurements from 175 glaciers, the researchers were able to show that the glaciers underwent ...

In this month's edition of Physics World, Paula Findlen from Stanford University profiles Laura Bassi -- an emblematic and influential physicist from the 18th century who can be regarded as the first ever woman to forge a professional scientific career. Once described as the "woman who understood Newton", Laura Bassi -- born in the city of Bologna in 1711 -- rose to celebrity status in Italy and all across the globe, gaining a reputation as being the best physics teacher of her generation and helping to develop the discipline of experimental physics. Bassi held numerous ...

A malaria control method that targets mosquito larvae and pupae as they mature in standing water could be an important supplementary measure in the fight against the disease, according to a new report. The Cochrane review -- led by the London School of Hygiene & Tropical Medicine in collaboration with Durham University and other researchers in the UK and US -- is the first systematic review looking at using larval source management (LSM) to control malaria, which causes an estimated 660,000 deaths worldwide every year. It found evidence that the method may significantly ...

The international consortium MetaHIT, which includes the research group of Jeroen Raes (VIB / Vrije Universiteit Brussel), publishes in the leading journal Nature that there is a link between richness of bacterial species in the intestines and the susceptibility for medical complications related to obesity. The researchers demonstrated that people with fewer bacterial species in their intestines are more likely to develop complications, such as cardiovascular diseases and diabetes. A flora with decreased bacterial richness appears to function entirely differently to the ...

CAMBRIDGE, Mass-- It's a long, expensive, risky road to turn a scientific breakthrough into a treatment that can help patients. Fewer organizations are trying to tackle the challenges alone, says a new paper from MIT researchers published August 28 in the journal Science Translational Medicine. An essential new way to move discoveries forward has emerged in the form of multi-stakeholder collaborations involving three or more different types of organizations, such as drug companies, government regulators and patient groups, write Magdalini Papadaki, a research associate, ...

CHAPEL HILL, N.C. -- Problems with a key group of enzymes called topoisomerases can have profound effects on the genetic machinery behind brain development and potentially lead to autism spectrum disorder (ASD), according to research announced today in the journal Nature. Scientists at the University of North Carolina School of Medicine have described a finding that represents a significant advance in the hunt for environmental factors behind autism and lends new insights into the disorder's genetic causes. "Our study shows the magnitude of what can happen if topoisomerases ...

An analysis of gravity and topography data from Saturn's largest moon, Titan, has revealed unexpected features of the moon's outer ice shell. The best explanation for the findings, the authors said, is that Titan's ice shell is rigid and that relatively small topographic features on the surface are associated with large roots extending into the underlying ocean. The study is published in the August 29 issue of the journal Nature. Led by planetary scientists Douglas Hemingway and Francis Nimmo at the University of California, Santa Cruz, the study used new data from NASA's ...

Here's a sobering fact for millions of young women heading back to school: The more alcohol they drink before motherhood, the greater their risk of future breast cancer. That's according to new research from Washington University School of Medicine in St. Louis that, for the first time, links increased breast cancer risk to drinking between early adolescence and first full-term pregnancy. Previous studies have looked at breast cancer risk and alcohol consumption later in life or at the effect of adolescent drinking on noncancerous breast disease. “More and more heavy ...

(SACRAMENTO, Calif.) — Stem cell technology has long offered the hope of regenerating tissue to repair broken or damaged neural tissue. Findings from a team of UC Davis investigators have brought this dream a step closer by developing a method to generate functioning brain cells that produce myelin — a fatty, insulating sheath essential to normal neural conduction. "Our findings represent an important conceptual advance in stem cell research," said Wenbin Deng, principal investigator of the study and associate professor at the UC Davis Department of Biochemistry and ...

Researchers have created a model that may explain the complexities of the origins of life. Their work, which appears in the Journal of the Royal Society Interface, offers new insights into how RNA signaling likely developed into the modern "genetic code." "Our model shows that today's genetic code probably resulted from a combination of selective forces and random chance," explained Justin Jee, a doctoral student at NYU School of Medicine and the paper's lead author. The study's other co-authors included: Bud Mishra, who has appointments at NYU's Courant Institute ...

Researchers at the National Institute of Allergy and Infectious Diseases (NIAID) and the National Heart, Lung, and Blood Institute, both part of the National Institutes of Health, have identified the cells in two distinct areas of the body that are simultaneously targeted for damage by anthrax toxins, eventually causing illness and sometimes death. Their findings, which appeared online today in Nature, are based on testing in mice. However, the results may contribute to the development of anthrax treatments for humans, the researchers say. Anthrax disease is caused by ...

ARCATA, Calif.—Woodland salamanders are a viable indicator of forest ecosystem recovery, according to researchers from the U.S. Forest Service's Pacific Southwest Research Station. PSW Research Wildlife Biologist Dr. Hartwell Welsh and Garth Hodgson examined two species of woodland salamanders across four stages of tree development at Mill Creek—a disturbed old-growth redwood forest in northern California. They found that the numbers and body condition of two common species of salamander tracked closely with forest stand growth, development, and structural changes. Using ...

When a beating heart slips into an irregular, life-threatening rhythm, the treatment is well known: deliver a burst of electric current from a pacemaker or defibrillator. But because the electricity itself can cause pain, tissue damage and other serious side-effects, a Johns Hopkins-led research team wants to replace these jolts with a kinder, gentler remedy: light. In a paper published Aug. 28 in the online journal Nature Communications, five biomedical engineers from Johns Hopkins and Stony Brook universities described their plan to use biological lab data and an intricate ...

GRAND RAPIDS, Mich. — Reversing inflammation in the fluid surrounding the brain's cortex may provide a solution to the complex riddle of Parkinson's, according to researchers who have found a link between pro-inflammatory biomarkers and the severity of symptoms such as fatigue, depression and anxiety in patients with the chronic disease. Lena Brundin of Michigan State University's College of Human Medicine was part of a research team that measured inflammatory markers found in cerebrospinal fluid samples of Parkinson's patients and members of a control group. "The degree ...

MADISON, Wis. – Teachers who practice "mindfulness" are better able to reduce their own levels of stress and prevent burnout, according to a new study conducted by the Center for Investigating Healthy Minds (CIHM) at the University of Wisconsin-Madison Waisman Center. The results of the study, led by Assistant Scientist Lisa Flook, were recently published in the journal Mind, Brain and Education. Mindfulness, a notion that stems from centuries-old meditative traditions and is now taught in a secular way, is a technique to heighten attention, empathy and other pro-social ...

VIDEO: A study led by University of Miami scientist Claire Paris, which appears in the Aug. 28 edition of PLOS ONE, was designed to test the response of larvae in a... Click here for more information. MIAMI – August 28, 2013 --How tiny fish larvae travel away from the reef, then know how to navigate their way back home is a scientific mystery. A new study led by Dr. Claire Paris, Professor at the University of Miami (UM) Rosenstiel School of Marine & Atmospheric Science ...

Cambridge, Mass. – August 28, 2013 – Research by environmental scientists at the Harvard School of Engineering and Applied Sciences (SEAS) brings bad news to the western United States, where firefighters are currently battling dozens of fires in at least 11 states. The Harvard team's study suggests wildfire seasons by 2050 will be about three weeks longer, up to twice as smoky, and will burn a wider area in the western states. The findings are based on a set of internationally recognized climate scenarios, decades of historical meteorological data, and records of past ...

An international team of researchers coordinated by ornithologist Bret Whitney of the LSU Museum of Natural Science, or LSUMNS, recently published 15 species of birds previously unknown to science. The formal description of these birds has been printed in a special volume of the "Handbook of the Birds of the World" series. Not since 1871 have so many new species of birds been introduced under a single cover, and all 15 discoveries involve a current or former LSU researcher or student. "Birds are, far and away, the best-known group of vertebrates, so describing a large ...

For the first time, astronomers have seen the image of a distant quasar split into multiple images by the effects of a cloud of ionized gas in our own Milky Way Galaxy. Such events were predicted as early as 1970, but the first evidence for one now has come from the National Science Foundation's Very Long Baseline Array (VLBA) radio telescope system. The scientists observed the quasar 2023+335, nearly 3 billion light-years from Earth, as part of a long-term study of ongoing changes in some 300 quasars. When they examined a series of images of 2023+335, they noted dramatic ...

Scientists at the Department of Energy's Oak Ridge National Laboratory have developed a new oxygen "sponge" that can easily absorb or shed oxygen atoms at low temperatures. Materials with these novel characteristics would be useful in devices such as rechargeable batteries, sensors, gas converters and fuel cells. Materials containing atoms that can switch back and forth between multiple oxidation states are technologically important but very rare in nature, says ORNL's Ho Nyung Lee, who led the international research team that published its findings in Nature Materials. ...

When NASA's Lunar Laser Communication Demonstration (LLCD) begins operation aboard the Lunar Atmosphere and Dust Environment Explorer (LADEE) mission managed by NASA's Ames Research Center in Moffett Field, Calif., it will attempt to show two-way laser communication beyond Earth is possible, expanding the possibility of transmitting huge amounts of data. This new ability could one day allow for 3-D High Definition video transmissions in deep space to become routine. "The goal of the LLCD experiment is to validate and build confidence in this technology so that future ...

This news release is available in French. Branched Bartonia (Bartonia paniculata), a threatened species, is a spindly annual plant that grows to 40 cm tall and has tiny white flowers. Researchers at Trent University compared genetic data from the two geographically distinct populations of this small wetland plant, and found that the Muskoka, Ontario ones are genetically very different from a core population found in New York State, 600 km away. This discovery suggests that the Branched Bartonia in Ontario is genetically unique, and therefore under a much greater threat ...

Using an instrument on NASA's Solar Dynamics Observatory, called the Helioseismic and Magnetic Imager, or HMI, scientists have overturned previous notions of how the sun's writhing insides move from equator to pole and back again, a key part of understanding how the dynamo works. Modeling this system also lies at the heart of improving predictions of the intensity of the next solar cycle. Using SDO, scientists see a performance of explosions and fountains on the solar surface. Shots of solar material leap into the air. Dark blemishes called sunspots grow, combine and ...

Chicago (August 28, 2013)—Surgeons at University Hospitals Case Medical Center, Cleveland, are working to reduce serious complications that have been known to occur with colorectal operations. In addition to using a set of pre-and postoperative standards that speed recovery which they have been publishing on for more than a decade, the researchers have validated yet another step surgeons can take to further reduce patients' hospital stays: adding a procedure called the transversus abdominis plane (TAP) block to patients' surgical care. The results of their study appear ...