SAN ANTONIO, Texas -- Adding the drug trastuzumab to chemotherapy prevents cancer recurrence and improves survival in a large number of women with early stage HER2-positive breast cancer. But trastuzumab does not stop tumors from returning in about 25 percent of patients — and oncologists haven't been able to identify these women before treatment. This situation may soon change, according to a Mayo Clinic study being presented at the 2012 CTRC-AACR San Antonio Breast Cancer Symposium. VIDEO ALERT: Video of Dr. Perez is available on the Mayo Clinic News Network. A team ...

SAN ANTONIO, TX (December 7, 2012)—Previous research has shown that a family of genes, proteins and enzymes called the uPA system (for urokinase plasminogen activator) plays an active role in different facets of cancer's biology, including tumor cell invasion, the spread of metastases, and the growth of a primary tumor. Mesupron® is a new small molecule inhibitor, taken as a pill, that inhibits the uPA system. The results from a recent phase II clinical study suggest that the drug could be a safe and first-line treatment that extends progression-free survival for metastatic ...

PITTSBURGH—A group of scientists from North America and Europe, including Carnegie Mellon University's Terry Collins, has developed a five-tiered testing system that manufacturers can use to ensure that the chemicals and consumer products they produce are free of harmful endocrine disrupting chemicals like BPA or DDT. Their study, "Designing Endocrine Disruption Out of the Next Generation of Chemicals," will be published in the January 2013 issue of the Royal Society of Chemistry journal Green Chemistry, and is currently available online. Endocrine disrupting chemicals, ...

Research has shown a decrease in levels of the isotope nitrogen-15 in core samples from Greenland ice starting around the time of the Industrial Revolution. The decrease has been attributed to a corresponding increase in nitrates associated with the burning of fossil fuels. However, new University of Washington research suggests that the decline in nitrogen-15 is more directly related to increased acidity in the atmosphere. The increased acidity can be traced to sulfur dioxide, which in the atmosphere is transformed to sulfuric acid, said Lei Geng, a UW research ...

The third tropical cyclone in the Southern Indian Ocean has been renamed Tropical Cyclone Claudia as NASA's Aqua satellite passed overhead.The AIRS instrument on Aqua captured infrared imagery of Claudia over two days that showed the western quadrant is most powerful part of the cyclone. Aqua flew over Tropical Cyclone Claudia on Dec. 6 at 1959 UTC (2:59 p.m. EST/U.S.) and Dec. 7 at 0811 UTC (3:11 a.m. EST/U.S.). The Atmospheric Infrared Sounder (AIRS) instrument analyzes storms in infrared light, and revealed the temperatures of clouds and sea surface around the storm. ...

The deadly typhoon that caused almost 300 deaths in the southern Philippines is making a loop in the South China Sea, and infrared NASA satellite data indicated that Bopha re-intensified. NASA's Aqua satellite passed over Bopha on Dec. 6 at 1811 UTC (1:11 p.m. EST, U.S.) and the Atmospheric Infrared Sounder (AIRS) instrument aboard captured an infrared look at the storm. The infrared data revealed where the coldest, highest cloud tops were. The coldest cloud tops indicate the strongest storms with the heaviest rain, and AIRS data revealed they surrounded the center of ...

Economic growth will rise to 3 percent in 2013 and 2014, while unemployment will drop to 7.3 percent by December of 2013, NJIT Leir Research Professor William V. Rapp, PhD, http://www.njit.edu/news/experts/rapp.php, told economists and others last week at the annual outlook symposium, http://www.chicagofed.org/webpages/events/eos_series.cfm, sponsored by the Chicago Federal Reserve Bank. The first Henry J. Leir Professor of International Trade and Business in the NJIT School of Management, Rapp was invited to participate in the annual event which draws the nation's ...

COLUMBIA, Mo. -- Approximately 250,000 people in the United States suffer from muscular dystrophy, which occurs when damaged muscle tissue is replaced with fibrous, bony or fatty tissue and loses function. Three years ago, University of Missouri scientists found a molecular compound that is vital to curing the disease, but they didn't know how to make the compound bind to the muscle cells. In a new study, published in the Proceedings of the National Academies of Science, MU School of Medicine scientists Yi Lai and Dongsheng Duan have discovered the missing pieces to this ...

As large organisms, trees face some remarkable challenges, particularly regarding long-distance transport and communication. In addition to moving water and nutrients from their roots to their leaves, they must also integrate cell-to-cell communication over large areas. Furthermore, in order to function as a single, cohesive organism they must be able to effectively and efficiently send vital substances—such as DNA regulating signals—long distances along a network of cells, sieve-tubes, and vessels. But how effective is this cell-to-cell communication and how far can ...

Gaping crevasses that penetrate upward from the bottom of the largest remaining ice shelf on the Antarctic Peninsula make it more susceptible to collapse, according to University of Colorado Boulder researchers who spent the last four Southern Hemisphere summers studying the massive floating sheet of ice that covers an area twice the size of Massachusetts. But the scientists also found that ribbons running through the Larsen C Ice Shelf – made up of a mixture of ice types that, together, are more prone to bending than breaking – make the shelf more resilient than it otherwise ...

Careful observers of the new "Black Marble" images of Earth at night released this week by NASA and the National Oceanic and Atmospheric Administration have noticed bright areas in the western part of Australia that are largely uninhabited. Why is this area so lit up, many have asked? Away from the cities, much of the night light observed by the NASA-NOAA Suomi NPP satellite in these images comes from wildfires. In the bright areas of western Australia, there are no nearby cities or industrial sites but, scientists have confirmed, there were fires in the area when Suomi ...

Storenvy, the popular online store builder that's home to over 25,000 independent storefronts, today launches a socially-curated shopping platform for browsing items from the stores it powers, as well as a full brand redesign. The new platform will change the way people discover and buy products from the world's creative businesses. "Right now, there isn't a go-to place on the web to buy from independent creative businesses, like industrial designers, fashion boutiques, clothing companies, nonprofits or musicians," founder and CEO Jon Crawford says. "Amazon ...

In a recently published overview of Ten Top Hotels in New York, the 5 Star JW Marriott Essex House New York has been rated as the best hotel in Manhattan by the international hotel booking site http://whichhotel4me.com/. A luxury hotel in Midtown Manhattan the JW Marriott Essex House New York is renowned for its excellent rooms, superb dining and world class customer service. Featuring panoramic park views and a range of top notch facilities including a swimming pool, business centre with secretarial service and meeting rooms, the hotel is close to all Manhattan's major ...

Nicholas Dracopoli, Vice President and Head of Oncology Biomarkers at Janssen R&D will give a plenary keynote presentation entitled "Why So Few Companion Diagnostics? The Difficulty of Translating Biological Data into Predictive Biomarkers" at GTC's Biomarker Summit 2013, taking place in San Francisco, CA on March 20-22, 2013. Translating complex genomic data into widely used clinical tests has been much slower than anticipated. FDA-approved diagnostic tests have only been approved to predict response to therapy for nine oncology drugs a decade after the ...

A unique health program offers exciting solutions for kids under 17 to make healthier lifestyle choices by engaging in exercise and healthy eating habits on their own time. KF30M, a newly released project on the popular crowd-funding site Indiegogo, promises to make healthy living for kid's fun, effective, accessible, and affordable. Created by Tom Sheehan, owner of Sunrise Health & Racquet, located in Massapequa, NY, and a founding board member of Full Potential Academy, a proposed charter school which combines a traditional academic curriculum with fitness and nutrition ...

With the Christmas season comes the fact that many people perform annual rituals of tradition without a clue as to why they do those rituals apart from "that's just what people do at Christmas". As an American society, we are used to seeing people bring home a cut evergreen tree to set in the middle of their living room and hang shiny things on it for weeks. It is the people asking themselves, "why do rational human beings do these things every year?" who will most enjoy the answers found in "The Secrets Behind Our Christmas Traditions Revealed" ...

Today, Multi-Visions Canada Inc announced a partnership with Emsisoft GmbH. Emsisoft, a fast-growing company is a leading European supplier of software technology for the generic detection of malicious code such as viruses, trojans, spyware, keyloggers, rootkits, and the likes. Multi-Visions signs-on as North American Exclusive distributors of Emsisoft's Retail and OEM Anti-Malware solution. The goal in this venture is to bring US and Canadian consumers the best virus detection and protection software for their homes and businesses. "We are very excited about ...

Health and wellness website Natural Girl Diary announced today that its new eBook, Food 101 - Gluten, is live on Amazon and is set to have a promotion period later this week. The promotional period is set for Thursday, December 6th through Saturday, December 8th and will allow anyone wanting to download the book to do so for free. The book will return to its retail price of $3.97 on Sunday, December 9th. Gluten was practically an unknown term 20 years ago that only those diagnosed with celiac disease were required to pay attention to. Now, 1 in every 16 people is diagnosed ...

According to Makeup Lighting 101, "Proper lighting is one of the most important parts of successful makeup application and is too often overlooked." Good makeup lighting fixtures should provide even illumination and excellent light quality. While traditional incandescent or fluorescent makeup lights serve their purpose, they come with many inherent limitations: large breakable bulbs, ample heat generation, fixed light color, and short lifespan. Applying the latest LED technology, Bella Lumiere is drastically changing the market by introducing an advanced LED makeup ...

ECMOD, which stands for 'every channel mastered optimised and delivered' serves the catalogue, home shopping and multi-channel retailing community, business-to-business distributors and pure-play online businesses. PacNet Services, an international payment processing company that serves the need of multi channel retailers worldwide, made full use of the networking opportunity to spread the word of their global payment capabilities. Brian Weeks, Head of Sales for PacNet's European arm, notes, "It was great to meet successful businesses who are expanding overseas, ...

Hiller's and Miller Poultry are helping Gleaners provide much-needed protein for families on Friday, December 7, 2012 at 11 a.m., when they present 5,200 pounds of chicken to Gleaners Community Food Bank of Southeastern Michigan (Gleaners), Michigan's largest food bank and emergency food provider. This donation represents 11,600 meals. The donation will be delivered at 11 a.m. at Hiller's in Plymouth - 15455 Haggerty Road at 5 Mile Road. In the last two weeks of December 2012, Gleaners will distribute 3 million pounds of food for hungry families across southeast Michigan. ...

Fisher & Phillips LLP announces Jennifer Achtert, Of Counsel in the San Francisco office, is named to the Top Women Attorneys in Northern California list by Super Lawyers. The Top Women Attorneys list, published in the December issue of San Francisco Magazine, was compiled from both the 2012 Northern California Super Lawyers and Rising Stars designees. Achtert was previously named to the Northern California Super Lawyers 2012 Edition - Rising Stars, which recognizes the top up-and-coming attorneys in the region. Achtert handles employment-related litigation, ...

Your guide to living a gluten free life filled with delicious and affordable baked goods! Amy Wingate, mother to a young daughter and a woman with a passion for cooking and maintaining a healthy body, has just released her new book "Gluten Free Baking Recipes". "After the birth of my almost 3 year old daughter my health declined not only affecting my body but my mind and self image of myself. After spending a fortune on doctors, I decided to take matters into my own hands and get healthy! Today I enjoy living a gluten free lifestyle that I originally ...

The Illinois Housing Development Authority (IHDA) has released an updated report indicating that the City of Berwyn has initiated twenty-two new residential mortgages through the Illinois Building Blocks Pilot Program. The program, managed through IHDA, offers a 30-year, fixed-rate mortgage featuring an affordable interest rate as well as a $10,000 forgivable loan over two years for down payment and closing cost assistance. Through the program, $2,997,729 has been committed to Berwyn homeowners through mortgages and forgivable loans. IHDA, Illinois's primary housing ...

Bar None Auction, a premiere commercial truck and heavy equipment auction, has announced they will be partnering with Proxibid for their live and online bidding broadcasts. Proxibid is the world's largest, most trusted online marketplace for buying and selling high value and specialized assets. The Company has developed the most innovative and comprehensive suite of services that will enable Bar None Auction to continue to evolve in the global auction marketplace and provide superior service to their clients. "Bar None Auction is committed to providing high-quality ...