A new drug for patients with acute myeloid leukemia (AML) marked by a specific type of genetic mutation has shown surprising promise in a Phase II clinical trial. In more than a third of participants, the leukemia was completely cleared from the bone marrow, and as a result, many of these patients were able to undergo potentially curative bone marrow transplants, according to investigators at the Johns Hopkins Kimmel Cancer Center and nine other academic medical centers around the world. Many of the participants who did well with the new drug, quizartinib or AC220, had ...

(ATLANTA, December 8, 2012) – Studies presented today at the 54th Annual Meeting of the American Society of Hematology (ASH) examine current treatment standards for patients with clotting disorders in an effort to improve outcomes. The studies evaluate long-held treatment standards and whether modifications in intensity and duration of therapy may offer equally effective outcomes while reducing toxicities and relapse rates. Although significant advances have been made in delivering new and improved therapies for clotting disorders, treatment still presents challenges; ...

Angiocidin, a novel tumor-inhibiting protein, has been shown to reduce acute myeloid leukemia (AML) cells in vivo by almost two-thirds in pre-clinical experiments. George P. Tuszynski, a professor of neuroscience in Temple University's School of Medicine who discovered Angiocidin, will present the findings during the American Society of Hematology's national meeting in Atlanta on Dec. 9. AML causes certain white blood cells to stop maturing, resulting in their uncontrolled proliferation, which can lead to suppression of the immune system and often fatal secondary problems ...

Grizzly Beatz is an up-and-coming hip-hop producer that is been able to produce high-quality instrumentals for a range of different artists. Recently, Grizzly Beatz launch their own website and blog, allowing individuals to logon, listen to the beats that are available on the website, and then make a purchase for as little as $12. Their goal to provide high-quality beats, at a reasonable price for up-and-coming artists, has made them one of the premier online rep production services. With hundreds of different beats available, both on their website for purchase, as well ...

iRedSoft Technology Inc announce the immediate release of JBatch It v6. JBatch It is a Batch Image Processor which takes away the mundane task of resizing, adding text caption, applying effects, fixing photo orientation and renaming image filenames. This would help increase productivity and minimizing mistakes made when handling large volume of digital photos. It supports JPEG, Single Page TIFF, PNG, BMP and GIF format. JBatch It v6 is a totally redesigned version of the application so as to support natively both the 32 Bit and 64 Bit Windows including the new Windows ...

This year Santa is bringing Christmas trees and catnip to Sunrise Village, just a few of the many holiday happenings at the Puyallup shopping center. In addition to holiday sales and individual merchant events, Sunrise Village's holiday activities include: Nov. 23 til gone (9 am - 9 pm): Puyallup South Hill Lions Club Christmas Tree Sales Now through Dec. 16: Secret Santa Toy Drive at Sleep Country USA Dec. 8-9 (10 am - 4 pm): Santa Claws Pet Photos & Pet Adoptions at PetSmart Dec. 9 (9 am to Noon): Breakfast with Santa at The RAM Dec. 10 (6 - 9 pm): ...

Livewire Concepts, Inc recently raised over $600 for Operation Smile, a nonprofit organization that performs surgeries for children born in third world countries with cleft palettes and other facial deformities. The cost of each surgery is $240, which is often too much for struggling families in impoverished nations The event was held at McFaddens in the Power and Light District. A raffle was held with giveaways from several local shops and restaurants as well as drink and food specials for all attending guests. The president of Livewire Concepts, C.J. Suggs said, "It's ...

Toddy Gear is now selling its popular Toddy Smart Cloth and Wedge for a limited time featuring whimsical designs from the new "Season's Cleanings" collection. Peppo, Midnight Moose, and Winter Wonderland Smart Cloths bring the festive side to cleaning electronics screens, while Santa, Elf, and Rudolph Wedges will cradle your hand-held devices with style. These functional and fashionable microfiber cleaning products make wonderful stocking stuffers for family, friends, and coworkers. The Wedge is an innovative and practical accessory for a number of electronic ...

of over 120 job seekers at their recent job fair held at Goodwill of North Georgia's Oakwood Career Center. The job fair was part of VoiceNation's recruitment campaign entitled "It's Your Turn to Answer the Call". The company is looking to fulfill Customer Service Representative positions for full and part-time shifts at their expanding call center in Buford. VoiceNation is one of the fastest growing answering services in the industry. Customer Service Representatives are needed to answer inbound calls, take orders, screen calls and provide event registration ...

AVAD LLC, one of North America's leading providers of custom electronics, has announced the availability of the all-new 2013 AVAD Product Catalog. The 172-page, full-color catalog features all of the latest products and technologies from the leading suppliers in the residential and commercial electronics industries. In addition to the comprehensive product details and specifications that customers have come to expect from AVAD's annual catalog, the 2013 catalog features the best brands and products in the company's history. The new guide, which will be available in printed ...

Contractor Management Services (CMS), the nation's full-service leader in Independent Contractor Management (ICM), has formally announced it has been accepted as a member in the National Federation of Independent Businesses (NFIB), a non-profit organization that represents the interests of its member small businesses in Washington D.C. and all 50 state capitals. The NFIB membership gives CMS a business-centric venue to connect with small businesses potentially facing issues such as worker misclassification. Members of CMS' senior management team will seek opportunities ...

Springdale, Ohio - After seasons of preparation, Beef 'O' Brady's will claim home court advantage in Springdale, Ohio on Dec. 17, 2012. But this isn't your dad's Beef 'O' Brady's - or even your older brother's for that matter. The new restaurant was built with Beef 'O' Brady's refreshed prototype in mind dubbed "Beef's 2.0." The new Springdale restaurant, located at 370 Glensprings Drive - a completely renovated former long-time Perkins building - features many new elements that can't be found at most Beef 'O' Brady's restaurants. Some of the changes include ...

The Washington County Chamber of Commerce, an organization that promotes and advances the interests of the Washington County business community, publicly recognized and expressed gratitude toward Peacock Keller partner and attorney Susan Mondik Key for her many years of valuable leadership and service. All told, Ms. Key supported the civic organization in a leadership capacity for six years. From 2006 to 2007, she served on the Chamber's board of directors and during 2008 and 2009, Ms. Key served as member-at-large of the organization's executive committee. In 2010, ...

A study released by Activity-Based Total Accountability (ABTA) Institute at the Florida Institute of Technology gives the State of Utah an A- for providing transparency to state spending data. Utah topped all 50 states for transparency according to the ABTA. The study analyzed each state's spending data and awarded a grade of A to F on the institute's state report card, which can be found at http://abta.fit.edu/report_card. On a grading scale ranging from 0 to 100 points, Utah recorded a score of 87 and was one of only three states receiving the highest grade of ...

"You may not save money on transportation," he says, "but the RateMyShipment.com TMS can significantly change the way you work with certain customers and/or suppliers for the better." RateMyShipment.com TMS cut down on the complexities. With supply chains becoming increasingly complex and highly reliant on capable transportation systems, managing via phone, fax, and e-mail has become a real burden for companies of all sizes. "Half the time shippers don't even know what rates they're paying because the numbers are scribbled on someone's credenza," ...

The New Jersey Association of Verismo Opera (Verismo Opera), the only grand, professional opera company based in northern New Jersey, is celebrating its 23rd season with the launch of its new season -- Love, Comedy, Obsession and Murder. Artistic Director and Met Opera luminary Lucine Amara invites soloists to audition for all roles in the company's new productions of Ruggiero Leoncavallo's I Pagliacci and Giacomo Puccini's Gianni Schicchi to be performed on Sunday, April 21 at 3:00 p.m. and Pietro Mascagni's Cavalleria Rusticana and Puccini's Suor Angelica on Sunday, ...

Wine-by-the-glass programs have always been a staple in the restaurant business, and John Metz has been on the forefront of wine by-the-glass programs since his first restaurant venture Hi Life Kitchen and Cocktails opened in 1997. In his role as Executive Chef and Co-founder, Metz has continued this trend at his growing concept, Marlow's Tavern. As the knowledge and sophistication of consumers in Atlanta continues to thrive, there is a shift in the way that wine is being served. Critical to this movement is Marlow's ability to serve a broad range of wines at their peak ...

Retail UX, a user experience strategy agency for top retailers, today released the Holiday 2012 Retail UX Audit. The Audit reflects retailers' efforts to introduce features that will make shopping easier, more effective, and more engaging on their e-commerce web sites. "The UX Audit gives retailers an objective competitive benchmark in the area of user experience feature sets," said Paul Bryan, Director of User Research and Design Strategy for Retail UX. To create the Audit, Retail UX reviewed the e-commerce web sites of 30 top retailers in Winter 2012. ...

Focus Softnet, the leading software development company, today announced the launch of Focus CRM version 2.0, a web application that packs even more features and functionalities than the previous version of the product. The new Focus CRM 2.0 is fully integrated with Outlook and works on most of the commonly used browsers such as Internet Explorer, Firefox and Safari. "We are pleased to launch our new CRM solution, which is a thin client application that provides the customers Business Intelligence reports and data inputs in real time. It enables organizations to ...

Landmark Exteriors, Inc., a Norwalk-based roofing, siding and gutter design and installation company founded in 1996, has been selected as the exclusive Connecticut-based authorized dealer and installer of Dow POWERHOUSE Solar Shingles, an award-winning residential roofing system that protects like a standard shingle, but also has embedded solar cells to power the home. In an announcement yesterday by Dow Solar, a business unit of The Dow Chemical Company, Landmark Exteriors was named an exclusive POWERHOUSE Authorized Dealer. In comparison to other solar roofing systems ...

Australian timeshare company Classic Holidays has seen a direct correlation between its expanded customer service program and its ability to retain and increase its membership base. Membership has now exceeded 45,000 families, with Classic Holidays now the largest privately owned timeshare company in Australia. The company is responsible for approximately 650 employees between sales staff, resort staff and corporate personnel, with the recent move to a new 100 seat call centre allowing Classic to bolster its customer service outreach and expand upon its award-winning ...

The United States Senate has made a very clear and impressive position against the growing surge of International Parental Child Abduction of American children. On Tuesday, December 4th, 2012 Senator Barbara Boxter's (D-CA) Senate Resolution 543 International Parental Child Abduction Resolution (Senate Resolution 543), that was co-sponsored by 27 additional Senators, passed a Senate voice vote. Resolution does so much more than condemn the horrible criminal and abusive act of parental child kidnapping, but calls for an immediate overhaul of U.S. Government policy and agency ...

Kathy Krantz Stewart has just come back from the UK from her big role in the film Pearls of Africa where she played Emily. This was filmed in Boxted Hall, a 700-year-old estate in England, and was also shot in Kenya. In addition, her sci-fi film, Master Race from Mars, is planned for distribution next year by Ytinifni Pictures. Kathy executive produced and plays Catherine in this film, which her husband wrote and directed. She is also starring next year in Cowgirl Romance, a family friendly western she is executive producing, shooting in the US. She has other projects planned, ...

The non-profit organization, Athletes for Education (AFE), is conducting a toy drive through Wednesday, December 19, 2012, to benefit children at local hospitals and schools. AFE will be collecting new, unwrapped toys for children up to the age of 14 at the following locations: Alliance Training Center, Otay Lakes Surgery Center, Jordan's Crazy Burgers and Hot Dogs and Valentino's Lounge in Chula Vista; Sanfilippo's Italian Restaurant on 5th Avenue; Little Caesars in Rancho Bernardo; American Factory Wheel on Twain Avenue; Carlsbad Surgery Center in Carlsbad; Coast Surgery ...

- Mike Hiller of Quakertown, PA has been promoted to Director of Metrology at Laboratory Testing Inc. (LTI). This position oversees all operations and develops the business strategy for LTI Metrology, the division of LTI that provides calibration and dimensional inspection services to customers in the nuclear, aerospace, medical, manufacturing, heat treating and commercial industries. Hiller is a graduate of Millersville University with a B.A. degree in Technology Education and is currently attending DeSales University for his M.B.A. in Management. He began working at ...