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Hospital-based neurologists worry about career burnout

2012-12-13
MAYWOOD, Il. - A survey has identified career burnout as a significant problem among neurologists who predominantly work with hospital inpatients. Nearly 29 percent of these "neurohospitalists" said they had experienced burnout, and 45.8 percent said they were concerned about burnout but had not yet experienced it. (Burnout was defined as maintaining a schedule so burdensome as to limit the time a physician will or could spend as a neurohospitalist.) Results were published in the December, 2012 issue of Neurology® Clinical Practice. Among the co-authors is Jose Biller, ...

Predicting risk of arrhythmias and sudden cardiac death: There's a computer model for that

2012-12-13
VIDEO: Scientists are using "virtual hearts " to better understand risk in real-world patients. Researcher Coeli Lopes, Ph.D., University of Rochester Medical Center, assistant professor at the Aab Cardiovascular Research Institute, describes... Click here for more information. A computer model of the heart wall predicted risk of irregular heart rhythms and sudden cardiac death in patients, paving the way for the use of more complex cardiac models to calculate the ...

New policy brief examines impact of occupational injuries and illnesses among low-wage workers

2012-12-13
WASHINGTON, D.C.—Low-wage workers, who make up a large and growing share of the U.S. workforce, are especially vulnerable to financial hits that can result from on-the-job injuries and illnesses, according to a policy brief released today by researchers at the George Washington University School of Public Health and Health Services (SPHHS). The policy brief, "Mom's off Work 'Cause She Got Hurt: The Economic Impact of Workplace Injuries and Illnesses in the U.S.'s Growing Low-Wage Workforce," was released along with a white paper showing that such workplace injuries and ...

Time restrictions on TV advertisements ineffective in reducing youth exposure to alcohol ads

2012-12-13
Efforts to reduce underage exposure to alcohol advertising by implementing time restrictions have not worked, according to new research from the Center on Alcohol Marketing and Youth (CAMY) at the Johns Hopkins Bloomberg School of Public Health and the Dutch Institute for Alcohol Policy. The report, published in the Journal of Public Affairs, confirms what Dutch researchers had already learned in that country: time restrictions on alcohol advertising actually increase teen exposure, because companies move the advertising to late night. In 2009, Dutch regulators sought ...

'Curiosity' can be positioned with eclipses

Curiosity can be positioned with eclipses
2012-12-13
Observations from 'Curiosity' when Mar's moon Phobos crosses in front of the sun, like in September, help us to understand exactly where the rover is on the red planet. Researchers at the Complutense University of Madrid (Spain) have developed a method for achieving precisely this. The exact location of Curiosity on the surface of Mars is determined using data transmitted from its antennas as well as the space probes that orbit the red planet. It is very unlikely that these systems would fail but in such an eventuality there would be an alternative for determining the ...

Uncovering a flaw in drug testing for chronic anxiety disorder

2012-12-13
Pre-clinical trials — the stage at which medications or therapies are tested on animals like laboratory mice — is a crucial part of drug development. It's only then that scientists can assess benefits and side effects before a drug is administered to patients. Now, Prof. Ilan Golani of Tel Aviv University's Department of Zoology and Sagol School for Neuroscience and his fellow researchers Prof. Yoav Benjamini of TAU's Department of Statistics and Operations Research and the Sagol School of Neuroscience, and Dr. Ehud Fonio of the Weizmann Institute are questioning the ...

UAlberta medical researchers discover new potential chemotherapy

2012-12-13
Medical researchers at the University of Alberta have discovered that knocking out a particular "partner" gene is the Achilles' heel of some cancers. Cancer causing genes often have a partner in crime, meaning when either of the two genes is active in cancer cells, the tumour grows. The challenge for researchers has been pinpointing the genes’ “lethal partners.” Loss of one of the partners alone isn’t deadly to the cell, but if both are gotten rid of, the cancer cells are destroyed. Faculty of Medicine & Dentistry researcher Michael Weinfeld and his collaborators, ...

New technique for minimally invasive robotic kidney cancer surgery

2012-12-13
DETROIT – Urologists at Henry Ford Hospital have developed a new technique that could make minimally invasive robotic partial nephrectomy procedures the norm, rather than the exception for kidney cancer patients. The technique spares the kidney, eliminates long hospital stays and provides better outcomes by giving the surgeon more time to perform the procedure. Dubbed ICE for Intracorporeal Cooling and Extraction, the technique may allow more kidney cancer patients to avoid conventional open surgery – now used in the vast majority of cases – and its possible complications, ...

Regenstrief study finds that generic drugs often have incorrect safety labeling

Regenstrief study finds that generic drugs often have incorrect safety labeling
2012-12-13
INDIANAPOLIS -- Despite U.S. Food and Drug Administration regulations requiring generic medications to carry identical warnings to those on corresponding brand-name products, a study by Regenstrief Institute researchers has found that more than two-thirds of generic drugs have safety-warning labels that differ from the equivalent brand-name drug. The investigators reviewed 9,105 product labels for over 1,500 drugs available on DailyMed, an online repository of labeling information maintained by the FDA and the National Library of Medicine. Of the 1,040 drugs with more ...

Novel NIST process is a low-cost route to ultrathin platinum films

Novel NIST process is a low-cost route to ultrathin platinum films
2012-12-13
A research group at the National Institute of Standards and Technology (NIST) has developed a relatively simple, fast and effective method of depositing uniform, ultrathin layers of platinum atoms on a surface.* The new process exploits an unexpected feature of electrodeposition of platinum—if you drive the reaction much more strongly than usual, a new reaction steps in to shuts down the metal deposition process, allowing an unprecedented level of control of the film thickness. Platinum is a widely used industrial catalyst—in automobile catalytic converters and hydrogen ...

Solar power prices to continue falling through 2025, experts say

Solar power prices to continue falling through 2025, experts say
2012-12-13
Prices for solar modules—the part of solar panels that produce electricity—will continue to fall, in line with the long-term trend since 1980, according to a survey of experts by Near Zero, , a nonprofit energy research organization. However, for prices to keep falling for the long term will require continued committment to research, such as on materials used for making solar modules. To get a sense of what future prices for solar power are likely to be, as well as other challenges and bottlenecks that the industry faces, Near Zero conducted a formal, quantitative survey ...

Tool could help uncover bias against female faculty in STEM fields

2012-12-13
A new Northwestern University study of professors in STEM fields at top research universities across the country shows that bias against women is ingrained in the workforce, despite a societal desire to believe workplace equality exists. The quantitative study of the complete publication records of more than 4,200 professors in seven STEM fields (science, technology, engineering and mathematics) confirms that, for some disciplines, female faculty do publish fewer papers than male faculty but not for lack of talent or effort. The researchers found the "productivity ...

Patients with family history of colorectal cancer may be at risk for aggressive form of the disease

Patients with family history of colorectal cancer may be at risk for aggressive form of the disease
2012-12-13
BOSTON--When people with a family history of colorectal cancer develop the disease, their tumors often carry a molecular sign that the cancer could be life-threatening and may require aggressive treatment, Dana-Farber Cancer Institute scientists report in a new study. The finding, reported in the Journal of the National Cancer Institute, draws on data from studies that have tracked the health of tens of thousands of people over several decades. It suggests that colorectal cancer patients could one day have their tumor tissue tested for the molecular sign, and, if necessary, ...

Targeted micro-bubbles detect artery inflammation, MU study finds

2012-12-13
COLUMBIA, Mo. — Heart disease is a leading cause of death throughout the world. Doctors say that it is important to detect heart disease early before it becomes too serious. Now, researchers at the University of Missouri have found a way that they believe could help detect heart disease before it progresses too far as well as identify patients who are at risk for strokes. In a study published in Medicine and Science in Sports and Exercise, Isabelle Masseau, an assistant teaching professor in the MU College of Veterinary Medicine, found that she could use targeted micro-bubbles ...

Delaying childbirth may reduce risk of an aggressive form of breast cancer

2012-12-13
SEATTLE – Younger women who wait at least 15 years after their first menstrual period to give birth to their first child may reduce their risk of an aggressive form of breast cancer by up to 60 percent, according to a Fred Hutchinson Cancer Research Center study. The findings, by Christopher I. Li, M.D., Ph.D., a member of the Public Health Sciences Division at Fred Hutch, are published online in Breast Cancer Research and Treatment. "We found that the interval between menarche and age at first live birth is inversely associated with the risk of triple-negative breast ...

Hubble census finds galaxies at redshifts 9 to 12

Hubble census finds galaxies at redshifts 9 to 12
2012-12-13
Astronomers using the NASA/ESA Hubble Space Telescope have uncovered seven primitive galaxies from a distant population that formed more than 13 billion years ago. In the process, their observations have put forward a candidate for the record for the most distant galaxy found to date (at redshift 11.9), and have shed new light on the earliest years of cosmic history. The galaxies are seen as they were when the Universe was less than 4 percent of its present age. A team of scientists using the Hubble Space Telescope has made new observations of the Hubble Ultra Deep Field ...

Notre Dame research may have important implications for combating diabetes

2012-12-13
Research by University of Notre Dame biochemist Anthony S. Serianni is providing new insights that could have important implications for understanding and treating diabetes. Serianni points out that biological compounds known as dicarbonyl sugars are produced inside the human body from the natural breakdown of the simple sugar, glucose. The formation of these sugars is enhanced in diabetic patients because glucose concentrations in the blood and plasma of diabetics are significantly elevated. "We investigated, under laboratory conditions that approximate those in the ...

Too big or just right? Optimal circle of friends depends on socioeconomic conditions

2012-12-13
Some people like to have a few close friends, while others prefer a wider social circle that is perhaps less deep. These preferences reflect people's personalities and individual circumstances — but is one approach to social networks "better" than the other? New research suggests that the optimal social networking strategy depends on socioeconomic conditions. Researchers Shigehiro Oishi of the University of Virginia and Selin Kesebir of the London Business School explore the benefits of social networking strategies in two studies published in Psychological Science, a ...

Caltech-led astronomers discover galaxies near cosmic dawn

Caltech-led astronomers discover galaxies near cosmic dawn
2012-12-13
PASADENA, Calif.—A team of astronomers led by the California Institute of Technology (Caltech) has used NASA's Hubble Space Telescope to discover seven of the most primitive and distant galaxies ever seen. One of the galaxies, the astronomers say, might be the all-time record holder—the galaxy as observed existed when the universe was merely 380 million years old. All of the newly discovered galaxies formed more than 13 billion years ago, when the universe was just about 4 percent of its present age, a period astronomers call the "cosmic dawn," when the first galaxies ...

NASA'S Hubble provides first census of galaxies near cosmic dawn

NASAS Hubble provides first census of galaxies near cosmic dawn
2012-12-13
WASHINGTON -- Using NASA's Hubble Space Telescope, astronomers have uncovered a previously unseen population of seven primitive galaxies that formed more than 13 billion years ago, when the universe was less than 4 percent of its present age. The deepest images to date from Hubble yield the first statistically robust sample of galaxies that tells how abundant they were close to the era when galaxies first formed. The results are from an ambitious Hubble survey of an intensively studied patch of sky known as the Ultra Deep Field (UDF). In the 2012 campaign, called UDF12, ...

Building better barley

2012-12-13
As one of the top 10 barley producers in the world, Canada faces a problem of adapting to the 'new normal' of a warmer, drier climate. The 2012 growing season was considered an average year on the Canadian Prairies, "but we still had a summer water deficit, and it is that type of condition we are trying to work with," said Scott Chang, a professor of soil science in the University of Alberta's Department of Renewable Resources in Edmonton, Canada. Chang teamed with fellow crop scientist Anthony Anyia of Alberta Innovates – Technology Futures in 2006, following a severe ...

Mercyhurst University study probes impact of climate change on ectotherms

2012-12-13
A new study by biologists at Mercyhurst University focuses on the influence of climate change, particularly warmer winters, on the survival and potential fecundity of cold-blooded animals. Cold blooded animals, or ectotherms, do not have an internal mechanism for regulating body temperature. Instead, they rely on solar energy captured by the environment. The purpose of the Mercyhurst study, a collaboration of Michael Elnitsky, Ph.D., assistant professor of biology; and students Drew Spacht and Seth Pezar, is to assess the current and future impacts of climate change ...

Stress-resilience/susceptibility traced to neurons in reward circuit

Stress-resilience/susceptibility traced to neurons in reward circuit
2012-12-13
A specific pattern of neuronal firing in a brain reward circuit instantly rendered mice vulnerable to depression-like behavior induced by acute severe stress, a study supported by the National Institutes of Health has found. When researchers used a high-tech method to mimic the pattern, previously resilient mice instantly succumbed to a depression-like syndrome of social withdrawal and reduced pleasure-seeking – they avoided other animals and lost their sweet tooth. When the firing pattern was inhibited in vulnerable mice, they instantly became resilient. "For the first ...

Astronomers catch jet from binge-eating black hole

Astronomers catch jet from binge-eating black hole
2012-12-13
Back in January, a new X-ray source flared and rapidly brightened in the Andromeda galaxy (M31), located 2.5 million light-years away. Classified as an ultraluminous X-ray source (ULX), the object is only the second ever seen in M31 and became the target of an intense observing campaign by orbiting X-ray telescopes -- including NASA's Swift -- and radio observatories on the ground. These efforts resulted in the first detection of radio-emitting jets from a stellar-mass black hole outside our own galaxy. A ULX is thought to be a binary system containing a black hole that ...

Protein strongest just before death

Protein strongest just before death
2012-12-13
Researchers at Michigan State University have discovered a protein that does its best work with one foot in the grave. The study, which appears in the current issue of the Journal of Biological Chemistry, focuses on the nontraditional lifestyle of Retinoblastoma tumor suppressor proteins, which could lead to new ways to treat cancer. "Retinoblastoma proteins are unique in that they use controlled destruction to do their jobs in a timely but restrained fashion," said Liang Zhang, a lead author and MSU cell and molecular biology graduate student. "This is an unusual way ...
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