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Breast cancer patients' fear of developing lymphedema far exceeds risk

2013-02-25
Chicago (February 25, 2013): Women who have had the lymph nodes under their arm surgically removed during breast cancer treatment are warned to avoid certain practices that can cause lymphedema—a condition that causes chronic, painless swelling in the arm. Now, a new study published in the March issue of the Journal of the American College of Surgeons suggests that the vast majority of women who undergo breast cancer operations worry about developing this complication and that this fear far exceeds their actual risk of getting lymphedema. In fact, most women adopt four ...

WCS Adirondack Park study shows exurban residences impact bird communities up to 200 meters away

2013-02-25
As part of the study, scientists sampled the presence of 20 species of birds both near and far from 30 rural residences in the Adirondack Park. Calculating their occurrence at increasing distances from the residences, they determined that "human-adapted" species are 36 percent more likely to occur near the homes than in the surrounding mixed hardwood-conifer forests, and that "human-sensitive" species were 26 percent less likely. Beyond 200 meters, occupancy rates were similar to the surrounding forest. The report appears in the current online edition of the Journal of ...

Extremely high estrogen levels may underlie complications of single-birth IVF pregnancies

2013-02-25
Massachusetts General Hospital (MGH) researchers have identified what may be a major factor behind the increased risk of two adverse outcomes in pregnancies conceived through in vitro fertilization (IVF). Two papers published in the journal Fertility and Sterility support the hypothesis that extremely high estrogen levels at the time of embryo transfer increase the risk that infants will be born small for their gestational age and the risk of preeclampsia, a dangerous condition that can threaten the lives of both mother and child. They also outline a protocol that reduced ...

New type of gene that regulates tumor suppressor PTEN identified

2013-02-25
Researchers at Karolinska Institutet in Sweden have identified a new so-called pseudogene that regulates the tumour-suppressing PTEN gene. They hope that this pseudogene will be able to control PTEN to reverse the tumour process, make the cancer tumour more sensitive to chemotherapy and to prevent the development of resistance. The findings, which are published in the scientific journal Nature Structural and Molecular Biology, can be of significance in the future development of cancer drugs. The development of tumours coincides with the activation of several cancer genes ...

Asthma drug found highly effective in treating chronic, severe hives and itch

2013-02-25
An international team of researchers has found that a once-a-month, high-dose injection of a commonly used asthma drug is highly effective in treating teens and adults chronically afflicted with hives and severe, itchy rash. The drug, omalizumab, was tested on 323 people at 55 medical centers for whom standard antihistamine therapy failed to quell their underlying, allergy-like reaction, known as chronic idiopathic urticaria or chronic spontaneous urticaria. "Physicians and patients may now have a fast, safe and well-tolerated treatment option to consider before prescribing ...

Study: Babies born by C-section at risk of developing allergies

Study: Babies born by C-section at risk of developing allergies
2013-02-25
DETROIT – For expectant moms who may contemplate the pros and cons of natural child birth or Caesarian section, a Henry Ford Hospital study suggests that C-section babies are susceptible to developing allergies by age two. Researchers found that babies born by C-section are five times more likely to develop allergies than babies born naturally when exposed to high levels of common allergens in the home such as those from dogs, cats and dust mites. The study is being presented Sunday at the American Academy of Allergy, Asthma and Immunology annual meeting in San Antonio. "This ...

Scientists find surprising new influence on cancer genes

Scientists find surprising new influence on cancer genes
2013-02-25
LA JOLLA, CA – February 24, 2013 – Small stretches of DNA in the human genome are known as "pseudogenes" because, while their sequences are nearly identical to those of various genes, they have long been thought to be non-coding "junk" DNA. But now, a new study led by scientists at The Scripps Research Institute (TSRI) shows how pseudogenes can regulate the activity of a cancer-related gene called PTEN. The study also shows that pseudogenes can be targeted to control PTEN's activity. Published in the latest issue of the journal Nature Structural & Molecular Biology, ...

Taking the gamble out of DNA sequencing

2013-02-25
Two USC scientists have developed an algorithm that could help make DNA sequencing affordable enough for clinics – and could be useful to researchers of all stripes. Andrew Smith, a computational biologist at the USC Dornsife College of Letters, Arts and Sciences, developed the algorithm along with USC graduate student Timothy Daley to help predict the value of sequencing more DNA, to be published in Nature Methods on February 24. Extracting information from the DNA means deciding how much to sequence: sequencing too little and you may not get the answers you are looking ...

Ability of brain to protect itself from damage revealed

2013-02-25
The origin of an innate ability the brain has to protect itself from damage that occurs in stroke has been explained for the first time. The Oxford University researchers hope that harnessing this inbuilt biological mechanism, identified in rats, could help in treating stroke and preventing other neurodegenerative diseases in the future. 'We have shown for the first time that the brain has mechanisms that it can use to protect itself and keep brain cells alive,' says Professor Alastair Buchan, Head of the Medical Sciences Division and Dean of the Medical School at Oxford ...

UN sustainable energy initiative could put world on a path to climate targets

2013-02-25
The new study in Nature Climate Change shows that reaching the 3 energy-related objectives proposed by the United Nations in their Sustainable Energy for All (SE4All) initiative, launched in 2011, would reduce emissions of greenhouse gases that contribute to climate change and, in combination with other measures, could help keep global temperature rise from exceeding the internationally agreed target level of 2°C. "Achievement of the 3 objectives would provide an important entry point into stringent climate protection," says Joeri Rogelj, ETH Zurich researcher and IIASA-affiliated ...

Pain from the brain

2013-02-25
Psychogenic diseases, formerly known as 'hysterical' illnesses, can have many severe symptoms such as painful cramps or paralysis but without any physical explanation. However, new research from the University of Cambridge and UCL (University College London) suggests that individuals with psychogenic disease, that is to say physical illness that stems from emotional or mental stresses, do have brains that function differently. The research was published today, 25 February, in the journal Brain. Psychogenic diseases may look very similar to illnesses caused by damage to ...

Laser mastery narrows down sources of superconductivity

Laser mastery narrows down sources of superconductivity
2013-02-25
UPTON, NY – Identifying the mysterious mechanism underlying high-temperature superconductivity (HTS) remains one of the most important and tantalizing puzzles in physics. This remarkable phenomenon allows electric current to pass with perfect efficiency through materials chilled to subzero temperatures, and it may play an essential role in revolutionizing the entire electricity chain, from generation to transmission and grid-scale storage. Pinning down one of the possible explanations for HTS—fleeting fluctuations called charge-density waves (CDWs)—could help solve the ...

Researchers at IRB Barcelona discover a general mechanism that accelerates tumor development

Researchers at IRB Barcelona discover a general mechanism that accelerates tumor development
2013-02-25
Cancer is characterized by uncontrolled cell division and growth. In order to identify new therapeutic targets through which to tackle the disease, scientists seek to clarify the mechanisms that control the expression of genes that favor the development of tumors, in processes such as uncontrolled cell division. Today, Nature has published a paper by the lab headed by Raúl Méndez, ICREA professor at the Institute for Research in Biomedicine (IRB Barcelona). The study describes a mechanism controlled by the CPEB1 protein that affects more than 200 genes related to cell proliferation ...

Fragments of continents hidden under lava in the Indian Ocean

2013-02-25
The islands Reunion and Mauritius, both well-known tourist destinations, are hiding a micro-continent, which has now been discovered. The continent fragment known as Mauritia detached about 60 million years ago while Madagascar and India drifted apart, and had been hidden under huge masses of lava. Such micro-continents in the oceans seem to occur more frequently than previously thought, says a study in the latest issue of Nature Geoscience ("A Precambrian microcontinent in the Indian Ocean," Nature Geoscience, Vol 6, doi: 10.1038/NGEO1736). The break-up of continents ...

Quantum algorithm breakthrough

2013-02-25
The team implemented the 'phase estimation algorithm' — a central quantum algorithm which achieves an exponential speedup over all classical algorithms. It lies at the heart of quantum computing and is a key sub-routine of many other important quantum algorithms, such as Shor's factoring algorithm and quantum simulations. Dr Xiao-Qi Zhou, who led the project, said: "Before our experiment, there had been several demonstrations of quantum algorithms, however, none of them implemented the quantum algorithm without knowing the answer in advance. This is because in the ...

Graphene: A material that multiplies the power of light

2013-02-25
Bottles, packaging, furniture, car parts... all made of plastic. Today we find it difficult to imagine our lives without this key material that revolutionized technology over the last century. There is wide-spread optimism in the scientific community that graphene will provide similar paradigm shifting advances in the decades to come. Mobile phones that fold, transparent and flexible solar panels, extra thin computers... the list of potential applications is endless. Scientists, industries and the European Commission are so convinced of the potential of graphene to revolutionize ...

Scientists find bone-marrow environment that helps produce infection-fighting T and B cells

Scientists find bone-marrow environment that helps produce infection-fighting T and B cells
2013-02-25
DALLAS – Feb. 24, 2013 – The Children's Medical Center Research Institute at UT Southwestern has deepened the understanding of the environment within bone marrow that nurtures stem cells, this time identifying the biological setting for specialized blood-forming cells that produce the infection-fighting white blood cells known as T cells and B cells. The research found that cells called early lymphoid progenitors, which are responsible for producing T cells and B cells, thrive in an environment known as an osteoblastic niche. The investigation, published online today ...

Distinct niches in bone marrow nurture blood stem cells

Distinct niches in bone marrow nurture blood stem cells
2013-02-25
In research that could one day improve the success of stem cell transplants and chemotherapy, scientists have found that distinct niches exist in bone marrow to nurture different types of blood stem cells. Stem cells in the blood are the precursors to infection-fighting white blood cells and oxygen-carrying red blood cells. The research, by a team at Washington University School of Medicine in St. Louis, is reported Feb. 24 in the advance online edition of Nature. The new findings, in mice, suggest that it may be possible to therapeutically target support cells in ...

Analytical trick accelerates protein studies

2013-02-25
MADISON – Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions. Proteins are essential building blocks of biology, used in muscle, brain, blood and hormones. If the genes are the blueprints, the proteins patterned on them are the hammers and tongs of life. Proteins are not only numerous — humans have more than a 100,000 varieties — but each one has a complex structure ...

MBL scientists find genes linked to human neurological disorders in sea lamprey genome

MBL scientists find genes linked to human neurological disorders in sea lamprey genome
2013-02-25
VIDEO: Jennifer Morgan and Ona Bloom are using an ugly fish with a beautiful spinal cord, the sea lamprey, to study mechanisms of recovery from spinal cord injury at the MBL... Click here for more information. MBL, WOODS HOLE, Mass.— Scientists at the Marine Biological Laboratory (MBL) have identified several genes linked to human neurological disorders, including Alzheimer's disease, Parkinson's disease and spinal cord injury, in the sea lamprey, a vertebrate fish whose ...

UC Santa Barbara scientists develop a whole new way of harvesting energy from the sun

2013-02-25
(Santa Barbara, Calif.) — A new method of harvesting the Sun's energy is emerging, thanks to scientists at UC Santa Barbara's Departments of Chemistry, Chemical Engineering, and Materials. Though still in its infancy, the research promises to convert sunlight into energy using a process based on metals that are more robust than many of the semiconductors used in conventional methods. The researchers' findings are published in the latest issue of the journal Nature Nanotechnology. "It is the first radically new and potentially workable alternative to semiconductor-based ...

Preventing chronic pain with stress management

2013-02-25
For chronic pain sufferers, such as people who develop back pain after a car accident, avoiding the harmful effects of stress may be key to managing their condition. This is particularly important for people with a smaller-than-average hippocampus, as these individuals seem to be particularly vulnerable to stress. These are the findings of a study by Dr. Pierre Rainville, PhD in Neuropsychology, Researcher at the Research Centre of the Institut universitaire de gériatrie de Montréal (IUGM) and Professor in the Faculty of Dentistry at Université de Montréal, along with Étienne ...

Screening could avert 12,000 lung cancer deaths each year in the United States

2013-02-25
Screening for lung cancer with low-dose computed tomography (LDCT) in all screening-eligible current and former smokers has the potential to avert approximately 12,000 lung cancer deaths each year in the United States. That is the conclusion of a new analysis published early online in CANCER, a peer-reviewed journal of the American Cancer Society. By providing a national estimate of potentially avertable lung cancer deaths, the study will help policy makers better understand the possible benefits of LDCT lung cancer screening. Despite substantial decreases in smoking ...

Majority of Missouri tan salons allow pre-teens

2013-02-25
AUDIO: There are 17 states that don’t have minimum age restrictions for the use of tanning beds in spite of the fact that studies have shown that there is a higher... Click here for more information. A survey of tanning salon operators in Missouri shows that 65 percent would allow children as young as 10 to 12 years old to use tanning beds. That's despite evidence that any tanning bed use increases the risk of all skin cancers, including melanoma, the deadliest form of skin cancer, ...

Most babies slow to grow catch up by early teens

2013-02-25
New parents are pleased when their baby gains weight as expected, but if the rate of weight gain is slow parents can become worried and concerned about their child's future size. New research from the Children of the 90s study at the University of Bristol shows that most babies who are slow to put on weight in the first nine months of life have caught up to within the normal range by the age of 13, but remain lighter and shorter than many of their peers. There are significant differences in the pattern of 'catchup', depending on the infant's age when the slow weight ...
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