Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in tumors, tumor inflammation, and metastasis. As a therapeutic target, miR-155 could potentially provide a new avenue of treatment when targeted with drugs to suppress its activity. The study was published in an online issue of Oncogene in January. MiR-155, which plays an important role in various physiological and pathological processes, is considered ...

JUPITER, FL, April 3, 2013 – Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations and coordination problems. The most well-known of these is Creutzfeldt-Jakob disease, which can be described as the naturally occurring human equivalent of mad cow disease. Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time identified a pair of drugs already approved for human use that ...

PubMed Central may draw readership away from biomedical journal sites, with this effect increasing over time. This finding—that PubMed Central directly competes with biomedical publishers—was published online in The FASEB Journal. In the study, Phillip M. Davis shows that as articles are deposited in PubMed Central, they draw readership away from the scientific journal even when journals themselves are providing free access to the articles. Over time, this may weaken the ability of journals to build communities of interest around research papers, impede the communication ...

University of Notre Dame researchers have successfully created three-dimensional anatomical models from CT scans using 3-D printing technology, a process that holds promise for medical professionals and their patients. A paper by the researchers, "3D Printing of Preclinical X-ray Computed Tomographic Data Sets," was published in the Journal of Visualized Experiments this week. The strategy was initiated last spring by then-freshman Evan Doney, a Glynn Family Honors student in the laboratory of W. Matthew Leevy, research assistant professor at the Notre Dame Integrated ...

Coral Gables, Fla. – April 2, 2013 -- New research from the University of Miami School of Business Administration offers marketers a strategy for how best to structure free giveaways with products in order to maximize sales. The study, just published in the Journal of Marketing, shows that when a product that triggers more emotion (called affect), such as makeup, is offered with a free gift, shoppers are more likely to buy that product if the type of gift is unknown than if the type of gift is revealed. So much so, that in this case, it can up to double the purchase ...

Bottom-up synthesis of nanowires through metal-catalyzed vapor phase epitaxy is a very attractive process to generate high-quality nanowires thus providing an additional degree of freedom in design of innovative devices that extend beyond what is achievable with the current technologies. In this nano-fabrication process, nanowires grow through the condensation of atoms released from a molecular vapor (called precursors) at the surface of metallic nano-droplets. Gold is broadly used to form these nano-droplets. This self-assembly of nanowires takes place spontaneously ...

Could drug addiction treatment of the future be as simple as an on/off switch in the brain? A study in rats has found that stimulating a key part of the brain reduces compulsive cocaine-seeking and suggests the possibility of changing addictive behavior generally. The study, published in Nature, was conducted by scientists at the Intramural Research Program of the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, and the University of California, San Francisco. "This exciting study offers a new direction of research for the treatment ...

Scientists have decoded the genome of the western painted turtle, one of the most abundant turtles on Earth, finding clues to their longevity and ability to survive without oxygen during long winters spent hibernating in ice-covered ponds. Understanding the natural mechanisms turtles use to protect the heart and brain from oxygen deprivation may one day improve treatments for heart attacks or strokes, the researchers say. Both can lead to severe disability or death within minutes in patients deprived of oxygen. The research team includes scientists at Washington University ...

Consumer-directed health plans (CDHPs) offer low premiums but high deductibles on the premise that patients who are faced with deductibles of $1,000 or more for individual coverage (or twice that for family coverage) will shop around for the best price for the health care. In practice, however, that's not the case, according to a new study by the USC Schaeffer Center for Health Policy and Economics and the RAND Corporation. Examining the consumer decisions with and without CDHPs when receiving nine common outpatient services (such as office visits, chest x-rays and ...

An instrument that will measure the composition of Mars' upper atmosphere has been integrated to NASA's Mars Atmosphere and Volatile EvolutioN (MAVEN) spacecraft. MAVEN has a scheduled launch date of Nov. 18. Engineers and scientists at NASA's Goddard Space Flight Center in Greenbelt, Md. in collaboration with partners at the University of Michigan, Ann Arbor; Battel Engineering, Scottsdale, Ariz.; and AMU Engineering, Miami, Fla. built the Neutral Gas and Ion Mass Spectrometer (NGIMS) instrument. "The NGIMS team is delighted to provide this instrument to the MAVEN ...

WASHINGTON--The first published results from the Alpha Magnetic Spectrometer (AMS), a major physics experiment operating on the International Space Station, were announced today by the AMS collaboration spokesman, Nobel Laureate Samuel Ting. The result is the most precise measurement to date of the ratio of positrons to electrons in cosmic rays. Measurements of this key ratio may eventually provide the world with our first glimpse into dark matter. The AMS experiment, developed under the leadership of Professor Ting, with support from the U.S. Department of Energy and ...

Researchers at the U.S. Department of Energy's Ames Laboratory, Iowa State University, and the University of Crete in Greece have found a new way to switch magnetism that is at least 1000 times faster than currently used in magnetic memory technologies. Magnetic switching is used to encode information in hard drives, magnetic random access memory and other computing devices. The discovery, reported in the April 4 issue of Nature, potentially opens the door to terahertz and faster memory speeds. Ames Laboratory physicist Jigang Wang and his team used short laser pulses ...

NORTHFIELD, ILL.— The emergence of molecular diagnostic testing in lung cancer offers new hope for patients battling the number one cancer killer in the United States and abroad. Now, for the first time after a decade of biomarker testing in lung cancer, a uniform approach for testing for the EGFR mutation and ALK rearrangement along with the availability of targeted therapies offer lung cancer patients the chance for improved quality of life and more time with their loved ones. The College of American Pathologists (CAP), the International Association for the Study of ...

VIDEO: A new study finds that newlyweds who are more satisfied with marriage are more likely to gain weight, according to psychologist Andrea L. Meltzer, lead researcher and an assistant professor... Click here for more information. On average, young newlyweds who are satisfied with their marriage gain weight in the early years after they exchange vows, putting them at increased risk for various health problems related to being overweight. That is the finding of a new study ...

A team of Virginia Tech researchers has discovered a way to extract large quantities of hydrogen from any plant, a breakthrough that has the potential to bring a low-cost, environmentally friendly fuel source to the world. "Our new process could help end our dependence on fossil fuels," said Y.H. Percival Zhang, an associate professor of biological systems engineering in the College of Agriculture and Life Sciences and the College of Engineering "Hydrogen is one of the most important biofuels of the future." Zhang and his team have succeeded in using xylose, the most ...

Researchers at the University of Montreal have found that the glycated hemoglobin levels of children with type 1 diabetes followed at its affiliated Sainte-Justine Mother and Child University Hospital (CHU Sainte-Justine) is correlated linearly and negatively with household income. Glycated hemoglobin is the binding of sugar to blood molecules – over time, high blood sugar levels lead to high levels of glycated hemoglobin, which means that it can be used to assess whether a patient properly controls his or her blood glucose level. "Our study highlights a marked disparity ...

DALLAS – April 4, 2013 – Physician-researchers at UT Southwestern Medical Center have identified a vulnerability of certain lung-cancer cells – a specific genetic weakness that can be exploited for new therapies. Although researchers have long known that mutant versions of the KRAS gene drive tumor formation and are key to cell survival in non-small cell lung cancer, the blocking of activated KRAS has proven difficult. For years, investigations have explored stopping lung cancer at this junction, which also would have an impact on many other cancers. KRAS mutations, for ...

Despite Dangers, One In Five Nursing Home Residents Are Given Antipsychotics Article provided by Knapp & Roberts Visit us at http://www.krattorneysneglect.com It would be shocking to walk into a nursing home and find dozens of patients restrained by straps and chains, unable to move simply because the restraints make it easier to control their behavior. Yet many residents of nursing homes across the United States face restraints, but not by straps. Antipsychotic drugs -- which are approved for use in patients with schizophrenia and other mental disorders ...

Florida criminal law: crime dropping in the rural areas of Hillsborough County Article provided by Bauer Crider & Parry Visit us at http://www.floridadefense.com Overall, the crime rate dropped by a respectable 7 percent in the more sparsely populated areas of Hillsborough County outside the Tampa metro, according to the Tampa Bay Times report about data recently released by law enforcement. Unincorporated numbers In Feb. 2013, the Hillsborough County, Fla., Sheriff's Office released crime data for the unincorporated parts of the county. The unincorporated ...

The consequences of property and debt division during a divorce Article provided by Rubin, Rubin & Wilcox Visit us at http://www.rrwlaw.com As part of the divorce process, all married couples must divide their marital property and their marital debt. When it comes to divorce, asset division can be challenging for all couples. However, when one is a billionaire, much more can be at stake. Billionaire divorce problems Oil tycoon and CEO of Continental Resources, Harold Hamm, is seeking a divorce from his wife, Sue Ann Hamm, in Oklahoma. Harold Hamm is estimated ...

U.S. Supreme Court considers warrantless drunk driving blood tests Article provided by Law Office of Derek W. Emmons, P.C. Visit us at http://www.criminallawyersanantonio.com Whenever police suspect that a person has committed a crime, one of their biggest priorities is securing evidence to support a conviction. However, the police do not have unlimited powers in this regard. Pursuant to the Fourth Amendment to the U.S. Constitution, every person in the United States has the right to be free from unreasonable searches and seizures. It isn't always clear, though, ...

Income tax tips for the newly divorced Article provided by Herbert W. Laine, P.C. Visit us at http://www.chesapeakelawoffice.com In the immediate aftermath of a divorce, there are a lot of issues that need to be sorted out. One of the more difficult tasks arises when new divorcees prepare their first income tax return after the marriage dissolution has been finalized. In most cases, this tax return will be very different from the returns the couple filed during the course of their marriage. Because post-divorce tax issues can be so complicated, new divorcees ...

Boating writer Robin G. Coles will be signing copies of her new book, Boating Secrets: 127 Top Tips to Help You Buy and/or Enjoy Your Boat at Loggerhead Marina in Daytona, FL on Saturday, April 6, 2013. The author will be available during the marina's first Saturday of the Month Cookout beginning at 12:00noon. Based on interviews with 11 marine industry experts, Coles' new book provides answers for both new boaters and old salts. Her questions answer a wide range of subjects, including how to buy the perfect boat, getting insured and financed, what's involved in ...

Change Making Change Fund, (CMC) a non-profit organization dedicated to helping children around the world through the collection of pocket change, today announced that Keep A Child Alive will be the recipient of non-designated donations in April 2013. All non-designated money donated this month to Change Making Change through convenient Coinstar kiosks will support a global effort to provide treatment, food and orphan care to those affected by HIV/AIDS in Africa and India. Co-founded by actress and musician Alicia Keys and Leigh Blake in 2003, Keep A Child Alive currently ...

Dr. Aric Giddens, a partner with the medical practice, Memphis Obstetrics and Gynecological Association, PC (MOGA) has been presented with the 2012 Physician Leadership Award from Saint Francis Hospital - Bartlett. According to Jeremy Clark, CEO of Saint Francis Hospital - Bartlett: "One of the factors which undoubtedly led to Dr. Giddens' selection for the annual physician leadership award was his involvement with the implementation of our hospital's electronic healthcare records system. Although this was a major project, I knew that we would ultimately succeed, ...