Using the technique that created Dolly the sheep, researchers from the RIKEN Center for Developmental Biology in Kobe, Japan have identified a way to produce healthy mouse clones that live a normal lifespan and can be sequentially cloned indefinitely. Their study is published today in the journal Cell Stem Cell. In an experiment that started in 2005, the team led by Dr. Teruhiko Wakayama has used a technique called somatic cell nuclear transfer (SNCT) to produce 581 clones of one original 'donor' mouse, through 25 consecutive rounds of cloning. SNCT is a widely ...

SAN FRANCISCO (March 7, 2013) —A nationwide study of women in Denmark who are of child-bearing age finds that those who are obese appear to have a much greater risk of heart attack or stroke, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. In fact, women with a high body mass index (BMI)—a measure of the body's fat content—that is indicative of obesity were twice as likely as those of normal weight to suffer a potentially life-threatening heart attack or stroke within just four to five years following childbirth. ...

The search for a less-expensive, sustainable source of biomass, or plant material, for producing gasoline, diesel and jet fuel has led scientists to duckweed, that fast-growing floating plant that turns ponds and lakes green. That's the topic of a report in ACS' journal Industrial & Engineering Chemistry Research. Christodoulos A. Floudas, Xin Xiao and colleagues explain that duckweed, an aquatic plant that floats on or near the surface of still or slow-moving freshwater, is ideal as a raw material for biofuel production. It grows fast, thrives in wastewater that has ...

In a step toward understanding and exploiting an exotic form of matter that has been sparking excitement for potential applications in a new genre of supercomputers, scientists are reporting the first identification of a naturally occurring "topological insulator" (TI). Their report on discovery of the material, retrieved from an abandoned gold mine in the Czech Republic, appears in the ACS journal Nano Letters. Pascal Gehring and colleagues point out that synthetic TIs, discovered only a decade ago, are regarded as a new horizon in materials science. Unlike conventional ...

WASHINGTON and NEW YORK—A report released today by the George Washington University School of Public Health and Health Services (SPHHS) and the RCHN Community Health Foundation offers the first-ever in-depth examination of health centers' role in access to family planning. The report finds that virtually all health centers furnish family planning services to some extent but for both financial and non-financial reasons, only 1 in 5 is able to offer access to the full range of contraceptive services. The report offers a series of recommendations to strengthen performance, ...

WASHINGTON – Older adults who haven't been in school for a while are as capable of learning from tests as younger adults and college students, according to new research published by the American Psychological Association. No matter their age or if they work or go to college full time, people appear to learn more when tested on material, rather than simply rereading or restudying information, according to research published online in the APA journal Psychology and Aging. "The use of testing as a way to learn new information has been thoroughly examined in young students. ...

São Paolo, March 7, 2013 – In the first gender benchmarking study of its kind, researchers have found that numbers of women in the science, technology and innovation fields are alarmingly low in the world's leading economies, and are actually on the decline in many, including the United States. Results from Brazil show that despite women having a strong representation in parts of the science, technology and innovation sector, and a slight increase in engineering, physics and computer science, overall numbers are on the decline. Brazil ranks the highest in this study ...

Climate change could lead to dozens of species of lizards becoming extinct within the next 50 years, according to new research published today. Globally it has been observed that lizards with viviparous reproduction (retention of embryos within the mother's body) are being threatened by changing weather patterns. A new study suggests that the evolution of this mode of reproduction, which is thought to be a key successful adaptation, could, in fact, be the species' downfall under global warming. Researchers from the University of Exeter and the University of Lincoln ...

PHILADELPHIA – It happens to everyone: You stay up late one night to finish an assignment, and the next day, you're exhausted. Humans aren't unique in that; all animals need sleep, and if they don't get it, they must make it up. The biological term for that pay-the-piper behavior is "sleep homeostasis," and now, thanks to a research team at the Perelman School of Medicine, University of Pennsylvania, one of the molecular players in this process has been identified – at least in nematode round worms. David Raizen, MD, PhD, assistant professor of Neurology, and his colleagues ...

Scientists are reporting an advance in re-engineering photosynthesis to transform plants into bio-factories that manufacture high-value ingredients for medicines, fabrics, fuels and other products. They report on the research in the journal ACS Synthetic Biology. Poul Erik Jensen and colleagues explain that photosynthesis does more than transform carbon dioxide and water into sugar and oxygen and generate energy. That process also produces a wealth of natural chemical compounds, many of which have potential uses in medicines and other commercial products. However, evolution ...

Chevy Chase, MD ––Exercise may play a key role in helping children cope with stressful situations, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). When they are exposed to everyday stressors, the study found sedentary children had surges of cortisol – a hormone linked to stress. The most active children had little or no increase in their cortisol levels in similar situations. "The findings suggest physical activity plays a role in mental health by buffering children from the effects ...

New software, which will allow GP practice managers to improve healthcare for chronic illnesses including strokes, Alzheimer's and cancer, will be unveiled by scientists from The University of Manchester next week (13 & 14 March). Experts have devised a computer programme which analyses how many patients in a practice have suffered from different conditions over a particular time period and identifies those who might require hospital treatment in the future. Against a back drop of a drive for NHS efficiency savings, they believe the software will help practice managers ...

Philadelphia, PA, March 7, 2013 – According to a 2012 World Health Organization report, over 35 million people worldwide currently have dementia, a number that is expected to double by 2030 (66 million) and triple by 2050 (115 million). Alzheimer's disease, the most common form of dementia, has no cure and there are currently only a handful of approved treatments that slow, but do not prevent, the progression of symptoms. New drug development, no matter the disease, is a slow, expensive, and risky process. Thus, innovative techniques to study and assess the possibilities ...

Services like Google Maps use algorithms to determine the fastest route from point A to point B—even factoring in real-time traffic information as you travel to redirect you if, for example, a parade is blocking part of your route. Now, a team of researchers from Spain and Japan have achieved this kind of traffic control for the connections in optical networks by using a new dynamic network management system—and it does Google Maps one better. If necessary, the flexible-grid system can also redirect the traffic-congesting parade to another street (by re-arranging one or ...

AUGUSTA, Ga. – Scientists have watched a mild traumatic brain injury play out in the living brain, prompting swelling that reduces blood flow and connections between neurons to die. "Even with a mild trauma, we found we still have these ischemic blood vessels and, if blood flow is not returned to normal, synapses start to die," said Dr. Sergei Kirov, neuroscientist and Director of the Human Brain Lab at the Medical College of Georgia at Georgia Regents University. They also found that subsequent waves of depolarization – when brain cells lose their normal positive and ...

Chevy Chase, MD ––Women who were diagnosed with gestational diabetes during pregnancy face a significantly higher risk of developing Type 2 diabetes in the future, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). The prospective cohort study tracked 843 women who were diagnosed with gestational diabetes between 1996 and 2003 at Cheil General Hospital in Seoul, South Korea. About 12.5 percent of the women developed Type 2 diabetes within two months of delivering their babies. During the ...

When hospitals hire more nurses with four-year degrees, patient deaths following common surgeries decrease, according to new research by the University of Pennsylvania School of Nursing's Center for Health Outcomes and Policy Research as reported in the March issue of the prestigious policy journal Health Affairs. Less than half the nation's nurses (45%) have baccalaureate degrees, according to the most recent data available (2008). If all 134 Pennsylvania hospitals involved in the study had increased the percentage of their nurses with four-year degrees by 10 percentage ...

Chevy Chase, MD ––Chinese women are less likely to develop cardiovascular disease if they have their first menstrual cycle or enter menopause later than their peers, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). The study also found earlier onset of menopause was associated with a higher risk of developing osteoporosis. The risk was significantly lower for women who were older than 50 when they underwent menopause. The findings could be used to identify women who are more likely to ...

NEW YORK, 7 March 2013 – Between 2011 and 2020, more than 140 million girls will become child brides, according to United Nations Population Fund (UNFPA). If current levels of child marriages hold, 14.2 million girls annually or 39,000 daily will marry too young. Furthermore, of the 140 million girls who will marry before the age of 18, 50 million will be under the age of 15. Despite the physical damage and the persistent discrimination to young girls, little progress has been made toward ending the practice of child marriage. In fact, the problem threatens to ...

They may have gained fame in the Steven Spielberg adventure film "Indiana Jones and the Kingdom of the Crystal Skull," but those quartz-crystal skulls that once ranked as a great enigma of archaeology are certifiably fake. And the current edition of Chemical & Engineering News, (C&EN) the weekly news magazine of the American Chemical Society, the world's largest scientific society, recalls the details of their rise and fall. In the article, Sarah Everts, C&EN's European science correspondent, delves back into history, explaining that the skull sculptures — supposedly ...

Seoul, March 7, 2013– In the first gender benchmarking study of its kind, researchers have found that numbers of women in the science, technology and innovation fields are alarmingly low in the world's leading economies, and are actually on the decline in others, including the United States. South Korea's low ranking in the study results reflects a substantial underrepresentation of females in public and economic life. South Korean ranks last of the countries in the study in female economic status, access to resources, supportive policy, and participation in the knowledge ...

Television advertising may drive over-diagnosis of high cholesterol and over-treatment with statins, according to a new study¹ by Dr. Jeff Niederdeppe from Cornell University in the US and colleagues. It appears that a trip to the doctor enquiring about statins advertised on TV often leads to a prescription. The work appears online in the Journal of General Internal Medicine², published by Springer. Coronary heart disease is the leading cause of death in the US, and high levels of LDL-cholesterol, or 'bad' cholesterol, are a major contributor. Statins have been proven ...

SAN FRANCISCO (March 7, 2013) —Patients diagnosed with post-traumatic stress disorder (PTSD) have a significantly higher risk of developing insulin resistance and metabolic syndrome, placing them at greater risk for heart disease and diabetes, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. Researchers say public health interventions are urgently needed to prevent PTSD-related metabolic disorder at its early, reversible stage. This retrospective study included 207,954 veterans in Southern California and Nevada ...

SAN FRANCISCO (March 7, 2013) — Pregnant women who have a reduced number of capillaries under their skin during pregnancy may be at heightened risk for preeclampsia, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. Researchers say monitoring such changes in small blood vessels early in pregnancy may allow for medical intervention long before the potentially life-threatening condition occurs. The study, conducted by researchers in England, evaluated 305 women early in pregnancy to determine whether measuring ...

SAN FRANCISCO (March 7, 2013) — African-American women who survive breast cancer are more likely to develop heart failure than other women who have beaten the disease, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. All told, these women have a 1.4-fold greater risk for heart failure compared to their white counterparts, though the likelihood of dying after developing heart failure is roughly the same. This trend remained even after taking other potential contributing factors into account, including age, high ...