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Second most common infection in the US proving harder to treat with current antibiotics

2012-11-13
Washington, D.C.— Certain types of bacteria responsible for causing urinary tract infections (UTIs), the second-most-common infection in the United States, are becoming more difficult to treat with current antibiotics, according to new research from Extending the Cure (ETC), a project of the Center for Disease Dynamics, Economics & Policy. ETC released the research via its online ResistanceMap, an online tool created to track changes in antibiotic drug use and resistance. This year, ResistanceMap features analysis using ETC's Drug Resistance Index, a way for non-experts ...

Scientists discover how stomach cancer spreads

2012-11-13
Scientists at the University of Liverpool have found that the production of a protein that prevents the growth and spread of cancerous cells is impaired in patients with gastric cancer. Cancer of the stomach is the second most common cause of death due to malignant disease worldwide. New research findings at Liverpool, however, could contribute to the development of future gastric cancer therapies by restoring the functions of a protein called, TGFβig-h3. The protein is released by cells called myofibroblasts, which form part of the supporting tissue around cancer ...

How do cells tell time? Scientists develop single-cell imaging to watch the cell clock

2012-11-13
COLUMBUS, Ohio – A new way to visualize single-cell activity in living zebrafish embryos has allowed scientists to clarify how cells line up in the right place at the right time to receive signals about the next phase of their life. Scientists developed the imaging tool in single living cells by fusing a protein defining the cells' cyclical behavior to a yellow fluorescent protein that allows for visualization. Zebrafish embryos are already transparent, but with this closer microscopic look at the earliest stages of life, the researchers have answered two long-standing ...

Powering lasers through heat

Powering lasers through heat
2012-11-13
This press release is available in German. Since its invention 50 years ago, laser light has conquered our daily life. Lasers of varying wave lengths and power are used in many parts of our life, from consumer electronics to telecommunication and medicine. However, not all wave lengths have been equally well researched. For the far infrared and terahertz regime quantum cascade lasers are the most important source of coherent radiation. Light amplification in such a cascade laser is achieved through a repeated pattern of specifically designed semi-conductor layers of ...

Sperm length variation is not a good sign for fertility

Sperm length variation is not a good sign for fertility
2012-11-13
PROVIDENCE, R.I. [Brown University] — Perhaps variety is the very spice of life, but as a matter of producing human life, it could be the bane of existence. That's the indication of a new study in the journal Human Reproduction that found men with wider variation in sperm length, particularly in the flagellum, had lower concentrations of sperm that could swim well. Those with more consistently made sperm seemed to have more capable ones. "Our study reveals that men who produce higher concentrations of competent swimming sperm also demonstrate less variation in the size ...

Computer memory could increase fivefold from advances in self-assembling polymers

Computer memory could increase fivefold from advances in self-assembling polymers
2012-11-13
AUSTIN, Texas — The storage capacity of hard disk drives could increase by a factor of five thanks to processes developed by chemists and engineers at The University of Texas at Austin. The researchers' technique, which relies on self-organizing substances known as block copolymers, was described this week in an article in Science. It's also being given a real-world test run in collaboration with HGST, one of the world's leading innovators in disk drives. "In the last few decades there's been a steady, exponential increase in the amount of information that can be stored ...

Human eye gives researchers visionary design for new, more natural lens technology

Human eye gives researchers visionary design for new, more natural lens technology
2012-11-13
WASHINGTON, Nov. 13—Drawing heavily upon nature for inspiration, a team of researchers has created a new artificial lens that is nearly identical to the natural lens of the human eye. This innovative lens, which is made up of thousands of nanoscale polymer layers, may one day provide a more natural performance in implantable lenses to replace damaged or diseased human eye lenses, as well as consumer vision products; it also may lead to superior ground and aerial surveillance technology. This work, which the Case Western Reserve University, Rose-Hulman Institute of Technology, ...

Doubling down against diabetes

2012-11-13
This press release is available in German. A collaboration between scientists in Munich, Germany and Bloomington, USA may have overcome one of the major challenges drug makers have struggled with for years: Delivering powerful nuclear hormones to specific tissues, while keeping them away from others. The teams led by physician Matthias Tschöp (Helmholtz Zentrum München, and Technische Universität München) and chemist Richard DiMarchi (Indiana University) used natural gut peptides targeting cell membrane receptors and engineered them to carry small steroids known to ...

New study examines how health affects happiness

2012-11-13
Fairfax, Va., (November 13, 2012) — A new study published in the Journal of Happiness Studies found that the degree to which a disease disrupts daily functioning is associated with reduced happiness. Lead author Erik Angner, associate professor of philosophy, economics and public policy at George Mason University, worked with an interdisciplinary team of researchers from the University of Alabama at Birmingham, the University of Chicago and the University of Massachusetts Medical School. The full study is available at http://www.springerlink.com/content/k5231631755g86g2/?MUD=MP. Previous ...

Advocacy for planned home birth not in patients' best interest

2012-11-13
Philadelphia, PA, November 13, 2012 – Advocates of planned home birth have emphasized its benefits for patient safety, patient satisfaction, cost effectiveness, and respect for women's rights. A clinical opinion paper published in the American Journal of Obstetrics and Gynecology critically evaluates each of these claims in its effort to identify professionally appropriate responses of obstetricians and other concerned physicians to planned home birth. Throughout the United States and Europe, planned home birth has seen increased activity in recent years. Professional ...

Study sheds light on genetic 'clock' in embryonic cells

2012-11-13
As they develop, vertebrate embryos form vertebrae in a sequential, time-controlled way. Scientists have determined previously that this process of body segmentation is controlled by a kind of "clock," regulated by the oscillating activity of certain genes within embryonic cells. But questions remain about how precisely this timing system works. A new international cross-disciplinary collaboration between physicists and molecular genetics researchers advances scientists' understanding of this crucial biological timing system. The study, co-authored by McGill University ...

Underemployment persists since recession, with youngest workers hardest hit

2012-11-13
DURHAM, N.H. – Underemployment has remained persistently high in the aftermath of the Great Recession with workers younger than 30 especially feeling the pinch, according to new research from the Carsey Institute at the University of New Hampshire. "While on the decline, these rates have yet to return to their prerecession levels. Moreover, as the recession and other economic forces keeps older workers in the economy, openings for full-time jobs for younger workers might remain limited in the short-term," said Justin Young, a doctoral student in sociology at UNH and a ...

Edison Pharmaceuticals announces initiation of EPI-743 Phase 2B Leigh Syndrome Clinical Trial

2012-11-13
Mountain View, California; November 13, 2012. Edison Pharmaceuticals today announced the initiation of a phase 2B study entitled, "A Phase 2B Randomized, Placebo-Controlled, Double-Blind Clinical Trial of EPI-743 in Children with Leigh Syndrome." Four clinical trial sites have been selected in the United States: Lucile Packard Children's Hospital, Stanford University Medical Center – Palo Alto, California; Akron Children's Hospital – Akron, Ohio; Seattle Children's Hospital – Seattle, Washington; and Texas Children's Hospital, Baylor University – Houston, Texas. The ...

A sip of resveratrol and a full p53: Ingredients for a successful cell death

2012-11-13
Rio de Janeiro, Brazil- Resveratrol is a naturally occurring dietary compound found in grapes, berries, and peanuts. This polyphenol protects plants against pathogens such as bacteria and fungi by inducing cell death in invading organisms. The compound was discovered in red wine in 1939 but by large did not attract the attention of the scientific community. More recently, pre-clinical studies have revealed the many beneficial properties of resveratrol. These include antidiabetic, cardioprotective, and chemopreventive effects. The latter has been associated to resveratrol ...

Should hyperbaric oxygen therapy be used to treat combat-related mild traumatic brain injury?

Should hyperbaric oxygen therapy be used to treat combat-related mild traumatic brain injury?
2012-11-13
New Rochelle, NY, November 13, 2012—The average incidence of traumatic brain injury (TBI) among service members deployed in Middle East conflict zones has increased 117% in recent years, mainly due to proximity to explosive blasts. Therapeutic exposure to a high oxygen environment was hoped to minimize the concussion symptoms resulting from mild TBI, but hyperbaric oxygen (HBO2) treatment may not offer significant advantages, according to an article in Journal of Neurotrauma, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free ...

Trying to save money? Ask for crisp new bills at the bank

2012-11-13
Consumers will spend more to get rid of worn bills because they evoke feelings of disgust but are more likely to hold on to crisp new currency, according to a new study in the Journal of Consumer Research. "The physical appearance of money can alter spending behavior. Consumers tend to infer that worn bills are used and contaminated, whereas crisp bills give them a sense of pride in owning bills that can be spent around others," write authors Fabrizio Di Muro (University of Winnipeg) and Theodore J. Noseworthy (University of Guelph). Does the physical appearance of ...

CU-NOAA study shows summer climate change, mostly warming

2012-11-13
Analysis of 90 years of observational data has revealed that summer climates in regions across the globe are changing -- mostly, but not always, warming --according to a new study led by a scientist from the Cooperative Institute for Research in Environmental Sciences headquartered at the University of Colorado Boulder. "It is the first time that we show on a local scale that there are significant changes in summer temperatures," said lead author CIRES scientist Irina Mahlstein. "This result shows us that we are experiencing a new summer climate regime in some regions." The ...

Frustrated FATshionistas: How do plus-sized consumers mobilize to demand better clothing options?

2012-11-13
Marginalized groups of consumers can mobilize as an online community to seek greater inclusion in and more choice from mainstream markets, according to a new study in the Journal of Consumer Research. "In order to gain greater inclusion in the mainstream market, fatshionistas have tried to persuade established companies to serve them better, publicized the offerings of companies that have tried meeting their needs, and looked for opportunities to interact with influential designers and retailers in order to influence them to do more to serve their needs," write authors ...

Can the addition of radiolabeled treatments improve outcomes in advanced metastatic disease?

Can the addition of radiolabeled treatments improve outcomes in advanced metastatic disease?
2012-11-13
New Rochelle, NY, November 12, 2012--Radiolabeled agents are powerful tools for targeting and killing cancer cells and may help improve outcomes and lengthen survival times of patients with advanced disease that has spread beyond the initial tumor site. Effective therapy for metastatic cancer requires a combination of treatments, and the benefits of adding radionuclide therapy are explored in three studies published in Journal of Clinical Investigation, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The articles are available free on the Journal of Clinical ...

Matching brands: Why do consumers prefer Tostitos salsa with Tostitos tortilla chips?

2012-11-13
Consumers prefer matching brands for products that are consumed together because they believe products from the same brand have been designed to go together, according to a new study in the Journal of Consumer Research. "How much do brand combinations affect how much consumers enjoy products that are consumed together? It seems that matching brand labels enhance enjoyment by encouraging consumers to believe that the products were tested and designed to go well together," write authors Ryan Rahinel and Joseph P. Redden (both University of Minnesota). In one study, consumers ...

Nature study reveals loss of essential blood cell gene leads to anemia

2012-11-13
Athens, Ga. – Scientists at the University of Georgia, Harvard Medical School and the University of Utah have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood. The study was published online Nov. 7 and will be in the Nov. 22 print edition of the journal Nature. The findings promise to advance the biomedical community's understanding and treatment of human anemias and mitochondrial diseases, both ...

Novice or expert: How do consumers increase their knowledge about products?

2012-11-13
Consumers seek out novel consumption experiences to increase their knowledge about products but do so selectively based on their level of expertise, according to a new study in the Journal of Consumer Research. "It has been said that experience is the best teacher. Perhaps the lessons learned through trying new experiences can help explain the reason consumers seek out novel experiences that do not necessarily offer the greatest satisfaction?" write authors Joshua J. Clarkson (University of Cincinnati), Chris Janiszewski (University of Florida), and Melissa D. Cinelli ...

Plants and soils could exacerbate climate change as global climate warms

2012-11-13
WASHINGTON — November 13, 2012 — Scientists from the American Meteorological Society (AMS) and University of California, Berkeley have demonstrated that plants and soils could release large amounts of carbon dioxide as global climate warms. This finding contrasts with the expectation that plants and soils will absorb carbon dioxide and is important because that additional carbon release from land surface could be a potent positive feedback that exacerbates climate warming. The study was published today in a Journal of Climate paper titled, "Carbon cycle uncertainty ...

'Coca-Cola' model for delivering malaria meds is a success, says Princeton researcher

2012-11-13
A controversial program that uses the private market to provide affordable malaria treatments to people in Africa has dramatically increased access to care and should be continued, according to a policy article by scholars including Ramanan Laxminarayan of Princeton University in the Nov. 2 issue of the journal Science. The researchers stated that the two-year old pilot program, which is up for renewal this November and enables reduced-price malaria drugs to be sold in shops and market stalls, successfully broadened the availability of effective malaria therapies and ...

Product choice: When are consumers most satisfied?

2012-11-13
Consumers may be less satisfied with the choices they make if their options are presented one at a time rather than all at once, according to a new study in the Journal of Consumer Research. "Sequentially presented choices create uncertainty. Consumers know that alternatives will become available in the future, but not what those alternatives will be. So there is always the possibility that a better option could later be available," write authors Cassie Mogilner (Wharton School of the University of Pennsylvania), Baba Shiv (Stanford University), and Sheena Iyengar (Columbia ...
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