DURHAM, N.C. – Adding a third anti-cancer agent to a current drug cocktail appears to have contributed to dramatic improvement in three infants with the most severe form of Pompe disease -- a rare, often-fatal genetic disorder characterized by low or no production of an enzyme crucial to survival. Duke researchers previously pioneered the development of the first effective treatment for Pompe disease via enzyme replacement therapy (ERT). ERT relies on a manufactured enzyme/protein to act as a substitute for the enzyme known to be lacking in patients with a particular disease. ...

Athens, Ga. – New research is revealing surprising connections between animal microbiomes—the communities of microbes that live inside animals' bodies—and animal behavior, according to a paper by University of Georgia ecologist Vanessa O. Ezenwa and her colleagues. The article, just published in the Perspectives section of the journal Science, reviews recent developments in this emerging research area and offers questions for future investigation. The paper grew out of a National Science Foundation-sponsored workshop on new ways to approach the study of animal behavior. ...

University of Iowa researchers have previously shown that an enzyme called CaM kinase II plays a pivotal role in the death of heart cells following a heart attack or other conditions that damage or stress heart muscle. Loss of beating heart cells is generally permanent and leads to heart failure, a serious, debilitating condition that affects 5.8 million people in the United States. Now the UI team, led by Mark Anderson, M.D., Ph.D., professor and head of internal medicine at the UI Carver College of Medicine, has honed in on how CaM kinase II triggers heart cell death ...

Three studies conducted as part of Wayne State University's Systems Biology of Epilepsy Project (SBEP) could result in new types of treatment for the disease and, as a bonus, for behavioral disorders as well. The SBEP started out with funds from the President's Research Enhancement Fund and spanned neurology, neuroscience, genetics and computational biology. It since has been supported by multiple National Institutes of Health-funded grants aimed at identifying the underlying causes of epilepsy, and it is uniquely integrated within the Comprehensive Epilepsy Program at ...

HOUSTON – (Oct. 11, 2012) – Early results of a Phase II intra-arterial stem cell trial for ischemic stroke showed no adverse events associated with the first 10 patients, allowing investigators to expand the study to a targeted total of 100 patients. The results were presented today by Sean Savitz, M.D., professor of neurology and director of the Stroke Program at The University of Texas Health Science Center at Houston (UTHealth), at the 8th World Stroke Congress in Brasilia, Brazil. The trial is the only randomized, double-blind, placebo-controlled intra-arterial clinical ...

The 16th tropical depression of the Atlantic Ocean season has formed northeast of the Bahamas and NOAA's GOES-14 satellite captured a visible image of the storm as it tracks to the southwest. NOAA's GOES-14 satellite captured a visible image of newborn Tropical Depression 16 (TD16) near the Bahamas on Oct. 11 at 7:45 a.m. EDT. TD16 appeared as a rounded area of clouds just northeast of the Bahamas and its western fringes were just off the Florida east coast. GOES-14 also showed another low pressure area with the potential for development a few hundred miles from the Windward ...

As Typhoon Prapiroon slowed down and became quasi-stationary in the Philippine Sea NASA's Terra satellite passed overhead and captured an image of the storm. NASA's Terra satellite passed over Typhoon Prapiroon on Oct. 11 at 0210 UTC (1010 p.m. EDT, Oct. 10) and the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument captured a visible image of the storm. The visible imagery clearly showed a small ragged eye, and microwave satellite imagery confirmed the eye. Satellite imagery also confirmed a well-defined low-level center of circulation. By 11 a.m. EDT ...

A new long-term study of human twins by University of Colorado Boulder researchers indicates the makeup of the population of bacteria bathing in their saliva is driven more by environmental factors than heritability. The study compares saliva samples from identical and fraternal twins to see how much "bacterial communities" in saliva vary from mouth to mouth at different points in time, said study leader and CU-Boulder Professor Kenneth Krauter. The twin studies show that the environment, rather than a person's genetic background, is more important in determining the ...

SALT LAKE CITY, Oct. 11, 2012 – Using gravitational "lenses" in space, University of Utah astronomers discovered that the centers of the biggest galaxies are growing denser – evidence of repeated collisions and mergers by massive galaxies with 100 billion stars. "We found that during the last 6 billion years, the matter that makes up massive elliptical galaxies is getting more concentrated toward the centers of those galaxies. This is evidence that big galaxies are crashing into other big galaxies to make even bigger galaxies," says astronomer Adam Bolton, principal ...

Exposure to ambient air pollution from traffic during infancy is associated with lung function deficits in children up to eight years of age, particularly among children sensitized to common allergens, according to a new study. "Earlier studies have shown that children are highly susceptible to the adverse effects of air pollution and suggest that exposure early in life may be particularly harmful," said researcher Göran Pershagen, MD, PhD, professor at the Karolinska Institutet Institute of Environmental Medicine in Stockholm, Sweden. "In our prospective birth cohort ...

A simple six-question quiz, typically used to assess disabilities in the elderly, could help doctors determine which kidney dialysis patients of any age are at the greatest risk of death, new Johns Hopkins research suggests. Believing that kidney failure mimics an accelerated body-wide aging process transplant surgeon Dorry L. Segev, M.D., Ph.D., and his colleagues turned to geriatric experts to examine mortality risk in patients undergoing dialysis. They found that those who needed assistance with one or more basic activities of daily living – feeding, dressing, walking, ...

Richard P. Brown, MD, a psychopharmacologist who integrates CAM (Complimentary and Alternative Medicine) into his treatments, will present an evening workshop on Friday, October 12, 2012, from 7 to 10 pm, at The New York Open Center, 22 E. 30th Street, New York, NY, 10016, entitled "Drug Free Approaches to Treating ADD/ADHD," for psychotherapists looking to complement their practices with herbs, nutrients, and mind-body techniques. Dr. Richard P. Brown will share up-to-date information about a range of treatments for children and adults with Attention Deficit ...

Innovative Results has teamed up with Compassion International and The Crossing church to use the profits from their Saturday morning Orange County boot camps to make a positive difference in the lives of needy children and their families. Innovative Results began holding their fundraising _a href="http://www.innovative-results.com/orange-county-fitness-boot-camps/"_Orange County boot camp_/a_ in May of 2012. Since then, Innovative Results has raised over $2500.00 to provide assistance not only to local families, but also to impoverished children and families ...

Breast Cancer Survivors travel a challenging path - whether it is worrying about the survival rates of breast cancer, or how to tailor the diet to best take care of your health during and after cancer treatment. PCC is here to address doubts and questions to post breast cancer treatment and how to take control of your health. Take part in Parkway Cancer Centre Breast Cancer Survivor's Workshop with doctors and experts on 13th October 2012. Details are as follows: Date: Saturday, 13th October 2012 Venue: Topaz Ballroom, Sheraton Towers Time: 1.00pm - 6.00pm Programme ...

Interexpat Pte. Ltd. (ExpatFinder.com), the Singapore headquartered Internet Services Company, today launched http://www.InternationalHealthNavigator.com, an easy-to-use health insurance comparison website. The free-to-use website helps consumers navigate through the complexities of international health insurance benefits, deductibles, coverage areas and much more. The simple, instant search tool allows consumers to quickly view health plans that suit their individual requirements. "We designed International Health Navigator to help consumers better handle their ...

William Tucker, the first black child born in America at Fort Monroe in Hampton, Virginia in 1624, is the inspiration behind William Tucker University (WTU). Seeking State of Virginia authority to operate as an undergraduate and graduate university, WTU is scheduled to open in 2013. The research and development of the William Tucker story and the University has been ongoing over the past thirty years by William's direct descendant granddaughter, the late Thelma Williams; many friends of the William Tucker Project; and the non-profit, Jobs Virginia Community Development ...

Super Talent Technology, a leader of NAND Flash storage solutions, today announced their fourth-generation Value SSD (VSSD), the VSSD Bolt. The new VSSD Bolt is perfect for business and home users who want the performance and durability gains of solid-state drives without breaking the budget. The Bolt features a second-generation SandForce® processor and offers fast read/write speeds of up to 250MB/second up to three times faster than previous-generation VSSDs. TRIM support and S.M.A.R.T. Command Transport (SCT) technology keep the Bolt performing like new and ...

Bennett's Curse Haunted Attraction is Maryland and DC's Best and Most Terrifying Award Winning Professional Haunted House. Rated as one of the Top Haunts in the nation by sources such as Tophaunts.com, MSN, AmericasBestHaunts.com, The Reader's Digest, Haunted America Tours, The Travel Channel, Hauntworld.com, Haunternet.com, Hauntedhouserating.com, Haunted Attraction Magazine and more... For over a decade the evolving tale of the demise of Castle Bennett's and the mind bending terror of the Sanctuary of Insanity has entertained and thrilled thousands. Zombie Kingdom ...

The conference will be held November 5-6, 2012, in Washington, DC at the Renaissance Downtown Hotel. Attendees will learn about and discuss recent and pending legislation, federal budget cuts, the relationship of government and industry, contracting efficiencies, best practices, and acquisition trends. Benefits from attending GCMC include: • Exposure to more than 25 educational sessions led by leaders from the field; • An exhibit hall with more than 50 sponsors and exhibitors offering critical contracting solutions; • A free Contract Management Career Fair with ...

Artlightenment is a unique art show with a great concept: art, artists and the art of existence. Now in its fourth year, Artlightenment has expanded from paintings, photography and sculpture to also include film, theatre and a cabaret evening. Robyn Morshead created the festival, and was pleased to announce the judges for the showcase this year. She said, "We have very prestigious judges in this year's Artlightenment and participants will be getting attention from the best Nashville has in the industry." The two major awards are the Artlightenment awards for ...

Hasslein Books has announced the pre-order availability of its upcoming publication, A Matter of Time: The Unauthorized Back to the Future Lexicon. The book is slated for release this Thanksgiving, and will be available on Amazon.com and via special-order in retail stores, as well as via wholesale. But in the meantime, fans can get a jump on their Christmas shopping by pre-ordering the book right now, at BTTF.com, the one-stop shop for all Back to the Future collecting needs. Back to the Future is one of the most successful and beloved film trilogies of all time. Starring ...

Links Players International (Links), a Christian golf ministry and a collection of local fellowships for golfers, today announced that its 3rd annual Charity Classic Golf Tournament raised more than $52,000 to support those who have little or no access to healthcare. Event proceeds will go directly to Links Players International and St. Joseph Hospital's community clinics, providers of comprehensive acute and chronic care for persons of all ages among Orange County's most vulnerable population. "We are honored to host this annual event to bring hope and support ...

Blue Aura is an award-winning manufacturer and marketer of high performance wireless or wireless-ready sound systems and accessories. The company is pleased to announce the retail availability of the retro-elegant v30 Blackline hybrid vacuum tube amplifier with an integrated DAC. The wireless-ready two-channel audio system uses valve technology to replace the full spectrum of sound lost through the digital conversion process, bringing music back to its original velvety warmth and exacting detail for retail, office or home environments. "The striking beauty and ...

One of the ways in which Good Hands Handyman is able to continue to serve the community by providing much needed repairs to homes of homeowners that are disabled, elderly and low income families, is though the donations from great partners like The Home Depot Dacula, Georgia. The Home Depot Dacula has answered the call to "Build It Forward" and provides much needed supplies, furniture and fixtures to Good Hands Handyman Nonprofit so that we can continue to help grant recipients with the home repairs they need. What is the "Build It Forward Campaign"? ...

Atlanta- based PARIO, INC., an award-winning interactive communications and learning company, has signed on as a major sponsor of the Wounded Warrior Horsemanship Events. These free events are organized by Warrior Outreach, Inc., a non-profit organization providing opportunities for all Soldiers, Veterans, and their families to interact with horses while achieving long-term individual and family success. PARIO, a company that has been proudly serving our United States Military and their families for over nine years, is privileged to be part of these events. As a first ...