A Cleveland Clinic study recently published in Blood Cancer Journal evaluated factors associated with delayed time to treatment with oral antimyeloma medications in patients with newly diagnosed multiple myeloma.  The research found a significant delay in the initiation of these more costly medications compared to the time to initiate any other treatment for multiple myeloma (including inpatient chemotherapy or more affordable corticosteroids), especially among Black and elderly patients. The retrospective study also identified independent predictors associated with delayed prescription fill. These findings highlight the urgent need to address barriers to ...

Texas A&M University is joining a new National Science Foundation (NSF) Engineering Research Center (ERC), led by Northwestern University, seeking to develop robots capable of enhancing human labor. A central goal of the Human AugmentatioN via Dexterity (HAND) center is to make robotic assistance accessible and applicable to a wide range of physical actions through an engineered system of dexterous robotic hands, AI-powered fine motor skills, human interface, as well as developing the workforce and training for the future. The five-year, $26 million grant also includes Carnegie-Mellon University and Florida A&M University, ...

https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2024.0034 Announcing a new article publication for Cardiovascular Innovations and Applications journal.  Aortic dissection (AD) is a fatal cardiovascular disease for which the key involved genes are largely unknown. The authors of this article aimed to identify promising AD biomarkers from high-throughput RNA expressing data. In the GSE98770 dataset, differentially expressed mRNAs (DE-mRNAs) and microRNAs (DE-microRNAs) were identified through differentially expressed gene analysis and gene set enrichment ...

In the latest of three online gambling surveys conducted by the University of Massachusetts Amherst, monthly gamblers in Massachusetts reported an increase in gambling intensity and gambling harms. In addition, their attitudes toward gambling have grown more negative. The online surveys – conducted in 2014, 2022 and 2023 – can’t be generalized to the overall population but give the Social and Economic Impacts of Gambling in Massachusetts (SEIGMA) research team a picture of changing behaviors and attitudes over time ...

The Wake Forest Institute for Regenerative Medicine (WFIRM) proudly announces the appointment of Tim Bertram, PhD, as its new Chief Ecosystem Officer. He will serve as the Chief Executive Officer (CEO) of the U.S. National Science Foundation (NSF) multi-million-dollar long-term investment in commercializing advanced regenerative medical technologies from leading North Carolina academic institutions.  With an illustrious career marked by innovation and leadership, Bertram brings decades of transformative ...

Davis, CA — The NEC Society, a nonprofit organization dedicated to preventing necrotizing enterocolitis (NEC), a devastating neonatal intestinal disease, proudly marks its 10th anniversary. Founded by Jennifer Canvasser after the tragic loss of her son, Micah, the organization works tirelessly to build a world without NEC, the disease that killed her child and claims another child every day in the United States. Canvasser shares, "Ten years ago, patient-families affected by NEC were isolated, and clinician-scientists worked in silos. Over the past decade, we've built an empowered community dedicated to transforming our pain into power and isolation into collaboration.”  Since ...

WINSTON-SALEM, N.C. – Aug. 29, 2024 – A new study from researchers at Wake Forest University School of Medicine is shedding light on how scientific evidence and the uncertainty surrounding three unproven therapeutics were portrayed by the U.S. news media during the early days of the COVID-19 pandemic. The findings appear online in the Journal of Medical Internet Research Infodemiology. For the study, the researchers conducted an analysis of 479 reports of hydroxychloroquine, remdesivir and/or convalescent plasma in traditional and online U.S. ...

This summer, Yishu Wang was awarded a $719,000 research grant from the United States Department of Energy (DOE) to study the dynamic and microscopic behaviors of magnets with quantum mechanical properties. Magnetism originates from electrons in a material. When the electrons in a material all spin in the same direction, as they do in metals like iron, the material is magnetic, with poles that attract or repel other magnetic materials. “Magnets that we are using today can be viewed as static orderings of electrons, analogous to the static pattern of brushstrokes in a painting,” said Wang, a joint assistant professor in the Department of Materials Science and Engineering ...

Terahertz communications represent the next frontier in wireless technology, promising data transmission rates far exceeding current systems. By operating at terahertz frequencies, these systems can support unprecedented bandwidth, enabling ultra-fast wireless communication and data transfer. However, one of the significant challenges in terahertz communications is effectively managing and utilising the available spectrum. The team has developed the first integrated terahertz polarisation (de)multiplexer implemented on a substrateless silicon base which they have successfully tested in the sub-terahertz J-band (220-330 GHz) for 6G communications and beyond. The University of Adelaide’s ...

Studies have shown that undergraduate students who participate in research activities under the guidance of a faculty mentor are more likely to finish college. That’s one of the many reasons universities like The University of Texas at Arlington are increasing their investment into undergraduate research. Such research opportunities are not offered at many two-year colleges. To help bridge this gap, Jianzhong Su, professor of mathematics at UTA, is piloting a new program where students from the North Lake campus of Dallas College can come to UT Arlington to participate in a paid research ...

The Department of Energy’s Oak Ridge National Laboratory added a new neutron scattering instrument to its powerhouse of discovery at the Spallation Neutron Source, charting new territory for neutron imaging through artificial intelligence. In July, DOE’s Office of Science approved the final commissioning of the Versatile Neutron Imaging Instrument, or VENUS. “It’s a dream come true,” said ORNL neutron scattering scientist Hassina Bilheux. “It has been an honor and privilege to ...

A machine-learning tool created by Weill Cornell Medicine and Hospital for Special Surgery (HSS) investigators can help distinguish subtypes of rheumatoid arthritis (RA), which may help scientists find ways to improve care for the complex condition. The study published Aug. 29 in Nature Communications shows that artificial intelligence and machine learning technologies can effectively and efficiently subtype pathology samples from patients with RA. “Our tool automates the analysis of pathology slides, which may one day lead to more precise and efficient disease diagnosis and personalized treatment for ...

An ancient gene is crucial for the development of the distinctive waist that divides the spider body plan in two, according to a study publishing August 29th in the open-access journal PLOS Biology by Emily Setton from the University of Wisconsin-Madison, US, and colleagues. The spider body is divided into two sections, separated by a narrow waist. Compared to insects and crustaceans, relatively little is known about embryonic development in spiders, and the genes involved in the formation of the spider waist are poorly understood. To investigate, researchers sequenced genes expressed in embryos of the Texas brown tarantula (Aphonopelma hentzi) ...

A new study paves the way to understanding biotic recovery after an ecological crisis in the Mediterranean Sea about 5.5 million years ago. An international team led by Konstantina Agiadi from the University of Vienna has now been able to quantify how marine biota was impacted by the salinization of the Mediterranean: Only 11 percent of the endemic species survived the crisis, and the biodiversity did not recover for at least another 1.7 million years. The study was just published in the renowned journal Science. Lithospheric movements throughout Earth history have repeatedly led to the isolation of regional seas from the ...

Staphylococcus aureus has the potential to develop durable vancomycin resistance, according to a study published August 28, 2024, in the open-access journal PLOS Pathogens by Samuel Blechman and Erik Wright from the University of Pittsburgh, USA. Despite decades of widespread treatment with the antibiotic vancomycin, vancomycin resistance among the bacterium S. aureus is extremely uncommon—only 16 such cases have reported in the U.S. to date. Vancomycin resistance mutations enable bacteria to grow in the presence of vancomycin, but they do so at a cost. Vancomycin-resistant S. aureus (VRSA) strains grow more slowly and will often lose their resistance mutations if vancomycin ...

A person’s exhaled breath – which provides information that could unveil diverse health insights – has been hard to analyze. Now, a novel “smart mask” provides real-time, non-invasive monitoring of what people exhale. The mask, dubbed EBCare, captures and analyzes exhaled breath condensate (EBC), and it offers a promising solution for continuous EBC analysis at an affordable cost. “The significance of EBCare lies in its role as a versatile, convenient, efficient, real-time research platform and solution in various medical domains, ...

Challenging long-held beliefs that bird nest building is solely influenced by genetics or the environment, researchers report that the white-browed sparrow weavers of the Kalahari Desert, Africa, build nests with distinct architectural styles that reflect group-specific cultural traditions. “Behavioral traditions in birds have been well documented for song, migration, foraging, and tool use. Here, we add building behavior and show that architectural styles emerge from birds that build together,” write the ...

Reactive oxygen species (ROS) from mitochondria are key drivers of genetic chaos in cancer by causing the collapse of micronuclear envelopes, a process that fuels the chromosomal instability (CIN) often observed in aggressive tumor behavior. These are the findings of two new studies. The findings identify key proteins in this destructive process – p62 and CHMP7 – revealing potential prognostic markers and therapeutic targets for high-CIN tumors. Errors in chromosome segregation during cell division can lead to chromosomal instability, a key feature of cancer. These errors result in the formation of micronuclei, which are small structures ...

A meta-analysis of Mediterranean Sea marine species reveals the profound impact of the Messinian Salinity Crisis – a drastic environmental event that resulted in the almost complete evaporation of the Mediterranean Sea roughly 5.5 million years ago. According to the new study’s findings, the event nearly reset the region’s biodiversity. The findings offer novel insights linking tectonic and palaeoceanographic changes to marine biodiversity, highlighting the significant role of salt giants in shaping biogeographic patterns, including those that still influence ecosystems today. The Messinian Salinity Crisis (MSC), ...

New study from Hebrew University reveals that marmoset monkeys use specific calls, known as "phee-calls," to name each other, a behavior previously known to exist only in humans, dolphins, and elephants. This discovery highlights the complexity of social communication in marmosets and suggests that their ability to vocally label each other may provide valuable insights into the evolution of human language. LINK to pictures https://drive.google.com/drive/folders/1VjzO-70hk27UVX_IuQ6FTsHgmCgk9PCH?usp=drive_link Credit for pictures and sound: David Omer Lab In a groundbreaking discovery, researchers from Hebrew ...

Personalized wearable devices that monitor people's health are on the rise. From watches to patches and other types of sensors, these smart devices can monitor heart activity, inflammation levels, and more to help patients better manage their health from their own homes. Now, a new type of wearable device can be added to the list: a high-tech paper mask that monitors one's breath.    Caltech's Wei Gao, professor of medical engineering, and his colleagues have developed a ...

In a study published in Science, researchers at Karolinska Institutet describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side effects. Morphine is a powerful painkiller that belongs to the group of opioids. It blocks signals in the pain pathways and also increases feelings of pleasure. Morphine acts on several central and peripheral pain pathways in the body, but the neural processes behind the pain relief have not previously been fully understood. Researchers have now investigated how morphine relieves pain using ...

Chemists at the University of Amsterdam have developed a method to furnish a range of molecules with a trifluoromethyl group attached to a sulphur, nitrogen or oxygen atom. Their procedure, which has just been published in Science, avoids the use of PFAS reagents. It thus provides an environmentally friendly synthesis route for pharmaceutical and agrochemical compounds that rely on the presence of the trifluoromethyl group. The straightforward and effective method was developed at the Flow Chemistry group at the Van ‘t Hoff Institute for Molecular Sciences ...

Scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) School of Dentistry created a first of its kind sleep apnea model for studying chronic pain. A study published July 30 in Science Signaling, explains the mechanism behind persistent pain related to obstructive sleep apnea. More than 100 million people worldwide are affected by obstructive sleep apnea. This health condition causes a person to stop breathing numerous times while they are sleeping. Reduced sleep time and sleep quality can lead to numerous health problems including chronic pain, which is diagnosed at a much higher rate ...

August 29, 2024 — Marijuana use is common among patients considering plastic surgery and is associated with elevated nicotine levels on laboratory tests, reports a paper in the September issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.  "We found that patients who report marijuana use also have elevated urine nicotine and cotinine levels ...