The Chamber Orchestra of Philadelphia's Music Director is the composer behind the music of new television mini-series, Parade's End, which premieres on HBO on Tuesday, February 26. Maestro Dirk Brosse's score encapsulates the period of World War I, in addition to the romance and drama of the core relationships in the story. Parade's End is a five-part television mini-series, made in collaboration by HBO, BBC and VRT. Based on the best-selling tetralogy of novels of the same name by Ford Madox Ford, it tells the story of an eradicative love triangle between an English ...

Trader Media Group is expecting to see an increase in new car sales of 2.7% in 2013 with new car registrations reaching 2.1 million. This increase will be driven by continued growth in the private sector as well as recovery in fleet registrations which started to pick up in the last few months of 2012. However, for growth over the next few years to be consistent the economy needs to recover and GDP needs to settle above the 2% mark before we would start to consider new car registrations getting back to pre-recession levels of over 2.4 million units. The unknown this ...

Aer Arann plans to join Europe's top tier of regional airlines by 2015 and to double its passenger numbers to over two million in five years, it has been announced.. The airline also confirmed a 32% rise in Aer Lingus Regional passenger numbers in 2012, with total passenger growth of 16% in the past two years. Announcing a 'new beginning' at the airline, Sean Brogan, Interim Chief Executive, Aer Arann outlined a package of measures to grow its customer base and route network, including: - Fleet renewal programme: the airline will be taking delivery of eight new ...

Winner Casino is proud to announce that Dr. Lovemore and Sultan's Gold have been chosen the Games of the Month for February. With love in the air during the month of February thanks to Valentine's Day, Dr. Lovemore is the obvious first choice for double comp points at Winner Casino. Dr. Lovemore features a 10,000 coin jackpot and lots of bonus features. The doctor's license plate is the wild symbol as well as top paying symbol. His pink pants lead to 20 free spins with all winnings doubled. Free spins can be re-triggered. Dr. Lovemore's scatter symbol is worth 250 ...

Europcar, the leader in car hire services in Europe, is bringing its customers the ultimate choice in luxury with the addition of BMW to the Prestige fleet for the very first time. Answering the demand from its customers, the Prestige by Europcar fleet has introduced a number of models from the BMW 3 and 5 Series range. Ensuring that customers can enjoy a world class driving experience, the vehicles on the Prestige fleet come with a number of options over and above the standard vehicle specification. The new BMWs are available to book now for collection in February. "BMW ...

Following six historic days of operations aboard the International Space Station, NASA's Robotic Refueling Mission, or RRM, demonstrated remotely controlled robots using current-day technology could refuel satellites not designed to be serviced. RRM tests from January 14-25 culminated in a first-of-its-kind robotic fluid transfer, a demonstration that could be a catalyst to expanded robotic satellite-servicing capabilities and lead to a greener, more sustainable space. NASA also hopes that RRM technologies may help boost the commercial satellite-servicing industry. ...

Now, there's a new way to invest in an online business without having to own or operate your own website. By taking the old concept of a traditional stock market, RankTrader has created a new marketplace for the buying and selling of virtual shares or vShares, of a website. Today we see many online entrepreneurs taking advantage of the ease of creating an online property and making money from advertising, internet marketing, e-commerce or even simply blogging. It's a rising trend and a new area to earn money. It may seem easy on the surface to make money online, but ...

Chagas disease, a deadly tropical infection caused by the protozoan parasite Trypanosoma cruzi and transmitted by biting insects called "kissing bugs," has begun to spread around the world, including the U.S. Yet current treatment is toxic and limited to the acute stage. In The Journal of Infectious Diseases (JID), Galina Lepesheva, Ph.D., and her colleagues at Vanderbilt University and Meharry Medical College report curing both the acute and chronic forms of the infection in mice with a small molecule, VNI. VNI specifically inhibits a T. cruzi enzyme essential for ...

Wednesday, February 13, 2013, Cleveland: Cleveland Clinic researchers have found that colorectal cancer outcomes could be improved with regular genetic screening for Lynch syndrome, the most common hereditary, adult-onset cause of colorectal cancer, as published in the online version of the Journal of Clinical Oncology. Lynch syndrome is the most common genetic cause of colon cancer in adults. The study found that a universal screening program of all colorectal cancers surgically removed at Cleveland Clinic resulted in increased identification of Lynch syndrome patients ...

NEW YORK, Feb. 14, 2013 – Nitric oxide, the versatile gas that helps increase blood flow, transmit nerve signals, and regulate immune function, appears to perform one more biological feat— prolonging the life of an organism and fortifying it against environmental stress, according to a new study. The study reveals that a roundworm called Caenorhabditis elegans, an animal widely used in laboratory studies of aging, lives significantly longer when fed bacteria capable of manufacturing nitric oxide. The tantalizing observation points to one of the mechanisms by which the ...

Restoring vision might sometimes be as simple as turning out the lights. That's according to a study reported on February 14 in Current Biology, a Cell Press publication, in which researchers examined kittens with a visual impairment known as amblyopia before and after they spent 10 days in complete darkness. Researchers Kevin Duffy and Donald Mitchell of Dalhousie University in Canada believe that exposure to darkness causes some parts of the visual system to revert to an early stage in development, when there is greater flexibility. "There may be ways to increase ...

Urinary-tract infections are the second most common bacterial infection in humans, and many of them are recurrent. A study published by Cell Press on February 14th in the journal Immunity reveals the cellular and molecular basis of recurrent bladder infections and suggests possible treatment strategies, such as vaccines, to prevent this common problem. "Our study shows for the first time that the bladder is unable to mount an effective immune response to bacteria, which could explain the high frequency of recurrent infections," says senior study author Soman Abraham ...

BOSTON, MA -- The genes activated for human speech are similar to the ones used by singing songbirds, new experiments suggest. These results, which are not yet published, show that gene products produced for speech in the cortical and basal ganglia regions of the human brain correspond to similar molecules in the vocal communication areas of the brains of zebra finches and budgerigars. But these molecules aren't found in the brains of doves and quails -- vocal birds that do not learn their sounds. "The results suggest that similar behavior and neural connectivity for ...

VIDEO: A pair of studies published by Cell Press on February 14th in the journal Cell sheds new light on genetic variation that may have played a key role in human... Click here for more information. A pair of studies published by Cell Press on February 14th in the journal Cell sheds new light on genetic variation that may have played a key role in human evolution. The study researchers used an animal model to study a gene variant that could have helped humans adapt to humid ...

Babies as young as seven months can distinguish between, and begin to learn, two languages with vastly different grammatical structures, according to new research from the University of British Columbia and Université Paris Descartes. Published today in the journal Nature Communications and presented at the 2013 Annual Meeting of the American Association for the Advancement of Science (AAAS) in Boston, the study shows that infants in bilingual environments use pitch and duration cues to discriminate between languages – such as English and Japanese – with opposite word ...

The first animal model of recent human evolution reveals that a single mutation produced several traits common in East Asian peoples, from thicker hair to denser sweat glands, an international team of researchers reports. The team, led by researchers from Harvard Medical School, Harvard University, the Broad Institute of MIT and Harvard, Massachusetts General Hospital, Fudan University and University College London, also modeled the spread of the gene mutation across Asia and North America, concluding that it most likely arose about 30,000 years ago in what is today ...

DURHAM, N.C. – Recurrent bladder infections, which are especially common among women, may result from a defect among the bladder's immune fighters that keeps them from remembering previous bacterial infections. The immune memory lapse can hamper a timely and effective attack, according to researchers at Duke Medicine and Duke-National University of Singapore. Their study, which involved mice, may provide a new route to develop vaccines and treatments for urinary tract infections, which are the second-most common infection and account for more than 8 million health care ...

A research team from Case Western Reserve University School of Medicine has discovered an approach that could make gene therapy dramatically more effective for patients. Led by professor Eric Arts, PhD, the scientists discovered that the process of gene therapy is missing essential elements thereby reducing the effectiveness of this treatment. Re-introducing this element into their model system suggests that improvements for gene therapy areon the horizon. The findings are detailed in the article, "A new genomic RNA packaging element in retroviruses and the interplay ...

BOSTON AND CAMBRIDGE, Mass.––Tumors are not factories for the mass production of identical cancer cells, but are, in reality, patchworks of cells with different patterns of gene mutations. In a new study, researchers at Dana-Farber Cancer Institute and the Broad Institute show, more fully than ever before, how these mutations shift and evolve over time in chronic lymphocytic leukemia (CLL) – providing a strobe-like look at the genetic past, present, and future of CLL tumors. Their report, which will be published online today by the journal Cell, suggests that evolution ...

Gene wars rage inside our cells, with invading DNA regularly threatening to subvert our human blueprint. Now, building on Nobel-Prize-winning findings, UC San Francisco researchers have discovered a molecular machine that helps protect a cell's genes against these DNA interlopers. The machine, named SCANR, recognizes and targets foreign DNA. The UCSF team identified it in yeast, but given the similarity of yeast and human cells, comparable mechanisms might also be found in humans, where they might serve to lower the burden of inherited human disease and death, the researchers ...

Teaching children about the environment can affect the knowledge and behaviour of their parents, according to new research. Scientists from Imperial College London surveyed the families of 160 schoolchildren in the Seychelles, some of whom took part in educational activities about the island's valuable wetland resources. They found that the parents of children who took part in the wetland activities were more knowledgeable about wetlands and, were more inclined to undertake 'environmentally friendly' behaviours such as conserving water in their homes. The findings ...

Supposedly 'primitive' reflexes may involve more sophisticated brain function than previously thought, according to researchers at Imperial College London. The Vestibular-Ocular Reflex (or VOR), common to most vertebrates, is what allows us to keep our eyes focused on a fixed point even while our heads are moving. Up until now, scientists had assumed this reflex was controlled by the lower brainstem, which regulates eating, sleeping and other low-level tasks. Researchers at Imperial's Division of Brain Sciences conducted tests to examine this reflex in left- and right-handed ...

AUGUSTA, Ga. – Scientists at the Georgia Regents University Cancer Center have identified an Indian plant, used for centuries to treat inflammation, fever and malaria, that could help kill cancer cells. Cancer cells typically avoid death by hijacking molecular chaperones that guide and protect the proteins that ensure normal cellular function and then tricking them into helping mutated versions of those proteins stay alive, says Dr. Ahmed Chadli, a researcher in the Molecular Chaperone Program at the GRU Cancer Center and senior author of the study named the Journal ...

LOS ANGELES (Feb. 14, 2013) – New research from the Los Angeles Biomedical Research Institute (LA BioMed) found a progestogen-only treatment halted bleeding in women suffering from extremely heavy periods, according to the study published online by the American Journal of Obstetrics and Gynecology. "Excessive uterine bleeding is a common problem we see in gynecological practices and emergency rooms. It can interfere with women's daily activities and put them at risk for anemia and other more serious health consequences caused by blood loss," said Anita L. Nelson, MD, ...

Our love of music and appreciation of musical harmony is learnt and not based on natural ability – a new study by University of Melbourne researchers has found. Associate Professor Neil McLachlan from the Melbourne School of Psychological Sciences said previous theories about how we appreciate music were based on the physical properties of sound, the ear itself and an innate ability to hear harmony. "Our study shows that musical harmony can be learnt and it is a matter of training the brain to hear the sounds," Associate Professor McLachlan said. "So if you thought ...