(CHICAGO)--Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could have major implications for future treatment of this often-debilitating condition. "Clinically, scientists have focused on trying to understand how cartilage and joints degenerate in osteoarthritis. But no one knows why it hurts," said Dr. Anne-Marie Malfait, associate professor of biochemistry and of internal medicine at Rush, who led ...

Australian scientists have shown how a 'transcription factor' causes breast cancer to develop an aggressive subtype that lacks sensitivity to oestrogen and does not respond to anti-oestrogen therapies such as Tamoxifen and aromatase inhibitors. Transcription factors are molecules that switch genes on or off. In this case, the transcription factor known as 'ELF5' inhibits sensitivity to oestrogen very early in the life of a breast cancer cell. In 2008, Associate Professor Chris Ormandy from Sydney's Garvan Institute of Medical Research showed that ELF5 was responsible ...

Lisa brings a lifetime of experience reading well over 20,000 hands from around the globe. Her readings include iconic film stars, rock stars, international CEO's, television personalities and people just like you. Lisa has an unparalleled history in Hand Analysis that brings a rich, deep understanding of human nature reflected in the lines on hand. Her latest e-book called "Relationship Rescue using CPR," teaches what your map of original programming is, and how to go beyond any conflicts. Lisa Greenfield is the founder and CEO of TruthinHand.com. Her business ...

MediPurpose(tm), a master distributor and manufacturer of medical products, today announced its endorsement of the 11th Annual International Sharps Injury Prevention Month. Promoted by the International Sharps Injury Prevention Society (ISIPS), the sharps injury awareness campaign is launched every December 1 in conjunction with World AIDS Day. According to the United States Department of Labor's Occupational Safety & Health Administration (OSHA), a sharps injury -- also known as a needlestick injury -- is a wound caused by a needle that accidentally punctures ...

The Ironman World Championship held annually in Kona, Hawaii, is renown for its grueling three-part course: a 2.4 mile swim, a 112-mile bicycle ride, and a 26.2 mile run. Many try out but few qualify for the televised athletic event. Dr. Bennett Isabella, Dakota Dental's family dentist in Apple Valley, MN, was one of the few. Having successfully finished the Florida Ironman Triathlon among the top three of his age bracket, Dr. Isabella was cleared to enter the Ironman World Championship held October 13, 2012. With a completion time of 9 hours and 32 minutes in Florida, ...

As friends and families come together to celebrate the Christmas holiday, the challenge is always how to make the moments last. GiftWorksPlus, a leader in the production of custom picture frames, offers a broad line of family photo frames to capture those festive memories and keep them alive throughout the year. Christmas picture frames, Hanukkah picture frames, family picture frames for every relative and friend, military welcome home gifts, and even memorial frames are available. To display several pictures at one time, see the 11x14 Center Family Name engravable frames ...

Fire Side Homes & Excavating is pleased to announce they will be working closely with iWebContent to improve their web presence. In today's world, it is important for businesses to have a website, as well as a blog, to ensure their success. Many customers turn to the Internet for information before they hire someone to complete a job for them. When they look for the right company, they want to find the information they need quickly and easily. This requires an experienced Internet marketing firm. Fire Side Homes & Excavating is a construction company that specializes ...

Government Auction will start off the New Year on a high note with a Jan. 1 sale featuring exclusive designer watches, fine jewelry and gold coins. The auction will begin at 6:30 a.m. Pacific time, with an opening bid of only $2 on most lots. The fine jewelry selection is led by a stunning 16.92-carat sapphire and diamond ring. Considered in ancient times represent holiness or the heavens, the blue sapphire was a favorite amongst kings, who believed the precious stone could attract Divine favor. The ring to be auctioned by Government Auction is made of 14K white gold ...

SBT Seabuckthorn International Inc. is pleased to announce that Douglas Kalman, formerly the Eastern Sales Manager of SBT Seabuckthorn, is their newest distributor. In his new role as an independent distributor of SBT Seabuckthorn products, Mr Kalman will focus on building relationships and business within the Naturopathic and holistic health care markets. WHAT GOES AROUND COMES AROUND After several years pursuing other interests, Doug Kalman has returned to Peachland, BC's SBT Seabuckthorn to leverage his extensive knowledge and experience towards educating and enrolling ...

Cut-It-Out Communications, Inc. (www.cioediting.com), a Westchester public relations agency, today announced it is instituting a statistical approach to evaluate keywords for its clients for search engine optimization (SEO). The method employed evaluates search engine behavior -- the number of people searching for any given keyword -- combined with competition, the number of people trying to optimize for the same keyword. The two parameters are compared to create a KEI (keyword effectiveness index): a high volume of searches with a low number of optimizers will create ...

Northwest Flyers, Inc., a provider of Aircraft Management and Private Jet Charter announced the addition of a Citation Ultra to it's ever expanding Chicago based fleet. With seating for up to 9 passengers the Citation Ultra can accommodate business and family travel alike. Fold away tray tables, mini galley, accessory power outlets, in-flight WI-FI, and ample leg room create unsurpassed passenger comfort. The Cessna Citation Ultra received high accolades from Flying magazine as "Best Business Jet" in 1994, one year after it went into production as an upgraded ...

Taylor Morrison is pleased to announce that it has begun construction in the Parrish community of River Plantation. Featured homes will include some of Taylor Morrison's most popular designs, all with four bedrooms and its trademark open space concepts. River Plantation is a community enjoyed by many for its peaceful location. With oversized homesites and pedestrian-friendly streets, this neighborhood has many of today's most sought-after amenities, including a beautiful clubhouse with swimming pool, a playground, tennis and basketball courts, a canoe launch with access ...

Oridel, a cosmetic skincare product line based on Long Island, NY, today announced their latest blog post about how to care for dry skin. The newest blog post features new tips on how to take care of dry skin, such as how to make your own masks to keep skin moisturized, what kind of skincare products you should buy and what causes dry skin. This article is the third in a series of articles on skin care tips for your skin using items that are readily available in your home. Founder, Marina Oridel, is a Russian born skincare expert. "There are so many catching ...

Odds are very good that over the length of your lifetime you or someone you've know has made several attempts to achieve a New Years resolution and gave up within the first few weeks of the brand new, life changing year but without the power of self hypnosis cds. It could actually be that you've made several attempts at these goals over your lifetime with a few successes here and there but slowly giving in to failure and then trying again next year. You're not alone. Most people experience these same up and downs repeatedly within a few days, weeks or months after setting ...

Katie G. Brisson has been named Vice President, Program, at the Community Foundation. In her new role Ms. Brisson will oversee the discretionary grantmaking programs at the Foundation. She has most recently served as senior program officer for the New Economy Initiative for Southeast Michigan, a $100 million economic development initiative funded by ten local, regional and national foundations and run by the Community Foundation. Ms. Brisson joined the Community Foundation as a program officer in 1999 and has managed a diverse portfolio of grants in the arts and culture, ...

Award winning Canadian author Diane Robinson will appear on 'Around The Region', an Alberta Canada television program that airs on Wednesdays at 7:30 pm on CITL-TV Bell 237 and Shaw 319. The show, hosted by Kahla Buchanan, features events and happenings around the Midwest and Lakeland regions in Alberta Canada. Robinson recently took home two major awards for her childrens book, 'Sir Princess Petra'. She was honored with the Lieutenant Governor of Alberta Emerging Artists Award for Children's Book Author. She also took 2nd place in the Purple Dragonfly Book awards for ...

Parkway SleepHealth Centers (http://www.parkwaysleep.com), a comprehensive sleep health center and innovative leader in the diagnosis and treatment of sleep disorders, has announced that the sleep center has released a podcast discussing the variety of sleep disorders and how to know if you are suffering from such a disorder. In this podcast, Brent Brandow, director of operations for Parkway SleepHealth Centers, discusses how sleep disorders are diagnosed, specific signs and symptoms of sleep disorders, how someone can distinguish between a few bad nights of sleep and an ...

Triangle Family Services (TFS) (https://www.tfsnc.org/), an organization dedicated to helping families in crisis, has announced its next series of financial literacy seminars. The organization's mission is to build a stronger community by strengthening the family, and one of the ways that it does this is through providing individual financial counseling services to families and individuals. These financial literacy workshops focus on a wide variety of topics, including foreclosure prevention, credit repair and ways to save. The schedule of workshops is as follows: - ...

Paragon Commercial Bank (http://www.paragoncommercial.com) has announced that Matt Davis has been named the bank's chief operating officer. In this position, Davis is responsible for overseeing the bank's day-to-day operations, credit administration and compliance. Prior to his new position, Davis served as Paragon's chief credit officer for the past ten years. Before joining Paragon, Davis worked as a corporate banker for Wachovia Bank in Charlotte with a marketing emphasis on operating companies between $10 and $100 million in revenue. In 1996, a career move took him ...

Robert Buhler, president of MMI Public Relations (http://www.mmipublicrelations.com), a full-service public relations firm, has announced that the firm has been named the agency of record for Fairfield Harbour (http://www.fhpoa.com), a residential boating and golf community located 15 minutes from historic New Bern, N.C. The community seeks to enhance the visibility of the many amenities the resort and retirement community has to offer. MMI will assist Fairfield Harbour in developing and implementing a public relations campaign to increase awareness of the community. QUOTES: ...

Jurliss Flowers, an Singapore renowned online florist (www.jurliss.com), launched her first Android floral app on 27 October 2012 to serve the world-wide Android phone users. The app is FREE and can be downloaded from Google Play Store by searching for "Jurliss". With the successful launch of iPhone app in April 2012 and was prevalently accepted by iPhone users, Android phone users had since made numeral request for Android app. By replicating the iPhone app GUI and structure, Android app was ready in two months' time. Unlike iPhone app, Android app supports ...

Yomeka Johnson, Chief Executive Officer of Living for Legacies, has been selected as a VIP Member of the Covington Who's Who Executive and Professional Registry. The selection recognizes Timber Yomeka Johnson's commitment to excellence in Non-Profit. Johnson, who began working in her industry in June of 2005, currently serves as owner and operator for her not-for-profit organization. Its mission is to help young girls, ladies, and women in the Jackson, Mississippi area with personal, emotional, mental, spiritual, and physical growth. The goal is to help young ladies ...

From broken bulbs to tangled lights, we have all had that moment when we open a holiday storage box only to find a jumbled mess (or worse). It's a dreaded moment for most as you know you will spend extra time, not to mention money, teasing out what is left of last year's Christmas decorations. The good news is that storage manufacturers have caught on to this problem and have responded with some great holiday storage concepts to get you from year to year with less hassle. There are four main villains when it comes to the holiday storage wars: Tangles, breakage, water ...

iGozen is a company that specializes in organic cleaning products including a fruit and vegetable wash, all purpose household organic cleaner and a meat and fish wash. Their new odor-eliminator products scheduled for pre-launch use a plant-based enzyme to break apart the bonds of odor-causing compounds on a molecular level. In this manner, both the odors themselves and any harmful contaminants are permanently removed. This is much different than other odor eliminators in the marketplace that only temporarily mask smells that are in the air or on surfaces. This new product ...

Joining the growing ranks of Popdose.com's multimedia arsenal, Staff Writers Chris Holmes and Dw Dunphy present the all-new Popdose podcast Platters That Matter on January 8, 2013. The latest addition to Popdose's rotating offerings, which include The Matt 'N Jeff Radio Hour and Songs Of Freedom, Platters That Matter is devoted to celebrating and dissecting classic albums with Popdose's recognized irreverence and devotion alike. On a monthly basis writers Chris Holmes (Popdose, The Man With The Gray Flannel Suit, and Cracked.com) and Dw Dunphy (Popdose, ThePengunRocks.com, ...