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First identification of a strong oral carcinogen in smokeless tobacco

2012-08-22
PHILADELPHIA, Aug. 22, 2012 — Scientists today reported identification of the first substance in smokeless tobacco that is a strong oral carcinogen ― a health risk for the 9 million users of chewing tobacco, snuff and related products in the U.S. ― and called upon the federal government to regulate or ban the substance. The researchers reported here at the 244th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society. The meeting, which continues through Thursday, features more than 8,600 reports on new developments ...

First evidence from humans on how alcohol may boost risk of cancer

2012-08-22
PHILADELPHIA, Aug. 22, 2012 — Almost 30 years after discovery of a link between alcohol consumption and certain forms of cancer, scientists are reporting the first evidence from research on people explaining how the popular beverage may be carcinogenic. The results, which have special implications for hundreds of millions of people of Asian descent, were reported here today at the 244th National Meeting & Exposition of the American Chemical Society. Silvia Balbo, Ph.D., who led the study, explained that the human body breaks down, or metabolizes, the alcohol in beer, ...

Good news for banana lovers: Help may be on the way to slow that rapid over-ripening

2012-08-22
PHILADELPHIA, Aug. 22, 2012 — A solution finally may be at hand for the number one consumer gripe about America's favorite fresh fruit ― bananas and their tendency to ripen, soften and rot into an unappetizing mush, seemingly in the blink of an eye. Scientists speaking here today at the 244th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society, described efforts to develop a spray-on coating that consumers could use to delay the ripening of those 6.4 billion pounds of bananas that people in the U.S. eat every year. The ...

New era in camouflage makeup: Shielding soldiers from searing heat of bomb blasts

2012-08-22
PHILADELPHIA, Aug. 22, 2012 — Camouflage face makeup for warfare is undergoing one of the most fundamental changes in thousands of years, as scientists today described a new face paint that both hides soldiers from the enemy and shields their faces from the searing heat of bomb blasts. Firefighters also could benefit from the new heat-resistant makeup, according to the report. It was part of a broader symposium on innovations in ingredients for personal care products held during the 244th National Meeting & Exposition of the American Chemical Society, the world's largest ...

Researchers find benefits to early intervention in addressing brain abnormalities

2012-08-22
Preemptive cognitive training—an early intervention to address neuropsychiatric deficiencies—can help the brain function normally later in life, a team of researchers has found through a series of experiments on laboratory rats. Their findings, which appear in the latest issue of the journal Neuron, hold promise for addressing a range of brain impairments in humans, including schizophrenia. The study was conducted by researchers at New York University's Center for Neural Science, the State University of New York (SUNY) Downstate Medical Center, NYU Langone Medical Center, ...

With a little training, signs of schizophrenia are averted

2012-08-22
Animals that literally have holes in their brains can go on to behave as normal adults if they've had the benefit of a little cognitive training in adolescence. That's according to new work in the August 23 Neuron, a Cell Press publication, featuring an animal model of schizophrenia, where rats with particular neonatal brain injuries develop schizophrenia-like symptoms. "The brain can be loaded with all sorts of problems," said André Fenton of New York University. "What this work shows is that experience can overcome those disabilities." Fenton's team made the discovery ...

Lawson researcher sings the baby blues

2012-08-22
LONDON, ON – The impact of bipolar disorder during pregnancy has been hotly contended among the research community. Now, a new study from Lawson Health Research Institute and Western University is sorting out the debate and calling for more targeted, prospective research. Bipolar disorder is characterized by depression, hypomania, or mania. It is most common among women, and its episodes are often concentrated during the height of the reproductive years. Bipolar disorder can lead to suicide, infanticide, and increased risk for psychiatric hospitalization during the ...

MMV develops framework to assess risk of resistance for antimalarial compounds

2012-08-22
Medicines for Malaria Venture has developed a framework to evaluate the risk of resistance for the antimalarial compounds in its portfolio. A paper based on this work: A framework for assessing the risk of resistance for antimalarials in development has been published in the Malaria Journal today. Resistance defines the longevity of every anti-infective drug, so it is important when developing new medicines for malaria, to check how easily promising antimalarial compounds will select for resistance. Once this is known, it facilitates the prioritization of not only the ...

More sophisticated wiring, not just bigger brain, helped humans evolve beyond chimps

More sophisticated wiring, not just bigger brain, helped humans evolve beyond chimps
2012-08-22
Human and chimp brains look anatomically similar because both evolved from the same ancestor millions of years ago. But where does the chimp brain end and the human brain begin? A new UCLA study pinpoints uniquely human patterns of gene activity in the brain that could shed light on how we evolved differently than our closest relative. Published Aug. 22 in the advance online edition of Neuron, these genes' identification could improve understanding of human brain diseases like autism and schizophrenia, as well as learning disorders and addictions. "Scientists usually ...

Lack of food increases hospital use by HIV-infected urban poor in SF

2012-08-22
UCSF researchers found that poor HIV-infected individuals living in San Francisco are significantly more likely to visit emergency rooms and to have hospital stays if they lack access to food of sufficient quality and quantity for a healthy life. "In the prior three months, a quarter of participants in the study reported an ER visit, and just over a tenth reported a hospitalization, which shows that we are dealing with a population with high levels of illness. But the food insecure people were even sicker than the food secure, which is consistent with their experiencing ...

Green tea compound shows promise for tackling cancer

Green tea compound shows promise for tackling cancer
2012-08-22
A compound found in green tea could be a weapon in treatments for tackling cancer, according to newly-published research at the University of Strathclyde in Glasgow, Scotland. The extract, known as epigallocatechin gallate, has been known to have preventative anti-cancer properties but fails to reach tumours when delivered by conventional intravenous administration. However, in initial laboratory tests at the Universities of Strathclyde and Glasgow, researchers used an approach which allowed the treatment to be delivered specifically to the tumours after intravenous ...

Glass offers improved means of storing UK's nuclear waste

2012-08-22
ILW makes up more than three quarters of the volume of material destined for geological disposal in the UK. (1) Currently the UK's preferred method is to encapsulate ILW in specially formulated cement. The waste is mixed with cement and sealed in steel drums, in preparation for disposal deep underground. Two studies, published in the latest issues of The Journal of Nuclear Materials and European Journal of Glass Science and Technology A show that turning this kind of waste into glass, a process called vitrification, could be a better method for its long-term storage, ...

Losing stream in our battle to predict and prevent invasive species

Losing stream in our battle to predict and prevent invasive species
2012-08-22
Invasive species – plants, animals, and microbes introduced to regions beyond their native range – carry a global price tag of $1.4 trillion dollars. They are responsible for the loss of natural resources and biodiversity, damages to infrastructure, and an uptick in infectious diseases. Not all non-native species pose a threat. Scientists around the world have spent the last several decades teasing apart the conditions that set the stage for debilitating invaders, like giant hogweed, zebra mussels, or gray squirrels. A number of hypotheses have emerged to help predict ...

Survival without water: A key trait of an aquatic invader to spread

Survival without water: A key trait of an aquatic invader to spread
2012-08-22
Nowadays, an increasing number of rivers and lakes are being invaded by exotic snails, which come from remote regions, and even other continents. Such species represent a threat to native species, as they compete for food or space with them. This is the case of the mudsnail Potamopyrgus antipodarum. This small aquatic snail is native to New Zealand, and has spread throughout rivers, lakes or streams in Europe, Australia, America and Asia. The invasion success of this mudsnail may be partly due to the ability of females to reproduce without participation of males (i.e. ...

Scientists quantify nanofiber health risk to workers

2012-08-22
Health risks posed to people who work with tiny fibres used in manufacturing industries could be reduced, thanks to new research. Research into the health risks posed by nanofibres – used to strengthen objects from tennis rackets to airplane wings – has pinpointed the lengths at which these fibres are harmful to the lungs. Nanofibres, which can be made from a range of materials including carbon, are about 1,000 times smaller than the width of a human hair and can reach the lung cavity when inhaled. This may lead to a cancer known as mesothelioma, which is known to ...

Thinking about kids? Man, you gotta shed the kilos

2012-08-22
Australian scientists studying the impact obesity has on pregnancy, are urging men to get 'match fit' before conceiving to assist with fetal development. Reproductive experts from the University of Melbourne's Department of Zoology have discovered that a father's obesity negatively impacts sperm, resulting in smaller fetuses, poor pregnancy success and reduced placental development. While the health risks surrounding obesity and pregnancy have largely been centred on overweight mothers, scientists from the University of Melbourne are putting the onus on men to shape ...

How to act if there is a fire on the AVE

How to act if there is a fire on the AVE
2012-08-22
Researchers at the University of Cantabria have used computer models to analyse the best way to evacuate the Spanish High Speed Train, AVE, in the case of fire. The involvement of the crew in organising the fast transfer of passengers, completing the process before the train comes to a halt and collective collaboration to assist those with reduced mobility are just some of the strategies to be followed. "In the event of fire on an AVE, two stages should be defined: the first is pre-evacuation in which passengers are transferred from one coach to another while the train ...

Male mice exposed to chronic social stress have anxious female offspring

2012-08-22
BOSTON (August 22, 2012) —A study in mice conducted by researchers at Tufts University School of Medicine (TUSM) suggests that a woman's risk of anxiety and dysfunctional social behavior may depend on the experiences of her parents, particularly fathers, when they were young. The study, published online in Biological Psychiatry, suggests that stress caused by chronic social instability during youth contributes to epigenetic changes in sperm cells that can lead to psychiatric disorders in female offspring across multiple generations. "The long-term effects of stress can ...

MR enterography is option for pediatric patients with Crohn disease

2012-08-22
Parents with children nine years old and older who have Crohn disease should ask their children's doctor about MR enterography as a replacement for small bowel x-rays or CT enterography, a new study indicates. Children with inflammatory bowel disease must often undergo repeated examinations, which, with x-rays and CT, could lead to significant radiation exposure, said William A. Faubion, Jr., MD, one of the authors of the study. "MR enterography does not require any radiation, however the patient does have to drink an oral contrast agent, must hold their breath at times ...

Johns Hopkins researchers return blood cells to stem cell state

2012-08-22
Johns Hopkins scientists have developed a reliable method to turn the clock back on blood cells, restoring them to a primitive stem cell state from which they can then develop into any other type of cell in the body. The work, described in the Aug. 8 issue of the journal Public Library of Science (PLoS), is "Chapter Two" in an ongoing effort to efficiently and consistently convert adult blood cells into stem cells that are highly qualified for clinical and research use in place of human embryonic stem cells, says Elias Zambidis, M.D., Ph.D., assistant professor of oncology ...

Typical IBD patients not represented in research studies

2012-08-22
Major randomized controlled trials of new therapies for inflammatory bowel disease (IBD) are conducted on patients who are not typical of those who physicians see in day-to-day practice, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association (AGA). The two major, often debilitating, illnesses that are recognized as IBD are ulcerative colitis and Crohn's disease. The introduction of biologics — the most prescribed medications for IBD patients — have dramatically impacted ...

Deadly outbreak of West Nile virus highlights urgent need for more research, funding

Deadly outbreak of West Nile virus highlights urgent need for more research, funding
2012-08-22
New Rochelle, NY, August 22, 2012–Mosquito-borne West Nile virus (WNV) caused 26 deaths already this year, and nearly 700 cases had been reported by mid-August according to the Centers for Disease Control and Prevention (CDC). WNV had become "old news" among the public and the media. Furthermore, funding to support research, training and education, and surveillance and vector control had waned. Now there is an urgent imperative to redouble our efforts to understand and control this dangerous virus. Vector-Borne and Zoonotic Diseases, a major peer-reviewed journal from Mary ...

In Fiji, marine protection gets local boost

In Fiji, marine protection gets local boost
2012-08-22
NEW YORK (August 20, 2012)—A new study by researchers from the Global Change Institute at the University of Queensland, the ARC Centre of Excellence for Coral Reef Studies at James Cook University, and the Wildlife Conservation Society has found that locally managed marine protected areas within Fiji are playing an increasingly important role in the nation's strategy to protect inshore habitats. The study estimates that by 2020, locally managed marine protected areas within the Fiji Locally Managed Marine Area (LMMA) network will effectively protect between 12-18 percent ...

Better monitoring of food quantity makes self-control easier

2012-08-22
MINNEAPOLIS / ST. PAUL (08/22/2012) —New research from the University of Minnesota's Carlson School of Management suggests learning how to stop enjoying unhealthy food sooner may play a pivotal role in combating America's obesity problem. The research, published in the Journal of Consumer Research, explores how satiation, defined as the drop in liking during repeated consumption, can be a positive mechanism when it lowers the desire for unhealthy foods. "When people talk about self-control, they really imply that self-control is willpower and that some people have it ...

Iowa State, Ames Lab researchers study the structure of drug resistance in tuberculosis

Iowa State, Ames Lab researchers study the structure of drug resistance in tuberculosis
2012-08-22
AMES, Iowa – Edward Yu took note of the facts – nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally drug-resistant strains – and decided to shift his research focus to tuberculosis. Yu, an Iowa State University and Ames Laboratory researcher, has described in the journal Nature the three-part structure that allows E. coli bacteria to pump out toxins and resist antibiotics. And now, in a paper published online by the journal Nucleic Acids Research, a research team led by Yu describes ...
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