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Single moms entering midlife may lead to public health crisis

2011-06-03
WASHINGTON, DC, May 26, 2011 — Unwed mothers face poorer health at midlife than do women who have children after marriage, according to a new nationwide study, which appears in the June 2011 issue of the American Sociological Review. Researchers found that women who had their first child outside of marriage described their health as poorer at age 40 than did other moms. This is the first U.S. study to document long-term negative health consequences for unwed mothers, and it has major implications for our society, said Kristi Williams, lead author of the study and associate ...

Use of clot busters for stroke increased from 2005 to 2009, but still low

2011-06-03
The use of clot-busting drugs to treat acute ischemic stroke increased from 2005 through 2009 — but is still low, according to research reported in Stroke: Journal of the American Heart Association. Clot-busting drugs are known as thrombolytics, and tissue plasminogen activator (tPA) is the only FDA-approved thrombolytic for treating acute ischemic stroke, which is caused by a blood clot in the brain. Although the study didn't follow patients after hospital discharge, "we believe that the increased treatment rate has the potential to reduce the overall burden of stroke ...

U of T scientist leads international team in quantum physics first

2011-06-03
TORONTO, ON - Quantum mechanics is famous for saying that a tree falling in a forest when there's no one there doesn't make a sound. Quantum mechanics also says that if anyone is listening, it interferes with and changes the tree. And so the famous paradox: how can we know reality if we cannot measure it without distorting it? An international team of researchers, led by University of Toronto physicist Aephraim Steinberg of the Centre for Quantum Information and Quantum Control, have found a way to do just that by applying a modern measurement technique to the historic ...

Work by UH evolutionary biologist may one day help with chronic diseases

Work by UH evolutionary biologist may one day help with chronic diseases
2011-06-03
HOUSTON, June 2, 2011 – Working to better predict general patterns of evolution, a University of Houston (UH) biologist and his team have discovered some surprising things about gene mutations that might one day make it possible to predict the progression of chronic disease. UH evolutionary biologist Timothy Cooper and his colleagues describe their findings in a paper titled "Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population." The report appears June 3 in Science, the world's leading journal of original scientific research, global news ...

Trans-Atlantic team announces Huntington's disease breakthrough

Trans-Atlantic team announces Huntingtons disease breakthrough
2011-06-03
Medical researchers may have uncovered a novel approach to treat an incurable and ultimately fatal neurodegenerative disease that affects hundreds of thousands of people. Two international studies, one led by the University of Leicester, and the other a collaboration with Leicester led by scientists in the USA, hold out promise for slowing down the development of Huntington's disease – and potentially, Alzheimer's and Parkinson's diseases. The research, which is in its early stages, represents an important milestone in understanding these debilitating conditions. Huntington's ...

Rett protein needed for adult neuron function

2011-06-03
HOUSTON (June 2, 2011) – The protein MeCP2 is porridge to the finicky neuron. Like Goldilocks, the neuron or brain cell needs the protein in just the right amount. Girls born with dysfunctional MeCP2 (methyl-CpG-binding protein 2) develop Rett syndrome, a neurological disorder. Too much MeCP2 can cause spasticity or developmental delay with autism-like symptoms in boys. Now, researchers at Baylor College of Medicine (www.bcm.edu) and Texas Children's Hospital (www.texaschildrens.org) have found that the neuron needs a steady supply of this protein for its entire existence. ...

Robotic mine vehicles successfully reanimated by UA engineering students using industry support

Robotic mine vehicles successfully reanimated by UA engineering students using industry support
2011-06-03
TUCSON, Ariz. (June 2, 2011) -- In just 10 weeks, a group of University of Arizona engineering students took five crates of surplus hardware and two heavy-duty test vehicles, which didn't run, and mixed them with youthful enthusiasm, tenacity and many long hours to build two robotic vehicles that successfully drove themselves around UA's test mine. It was no easy task, and predicted by some as too big a project for a one semester course: ENGR 450/550, autonomous vehicle systems. But the naysayers didn't factor in the can-do attitude of 23 undergraduate and graduate students ...

Mega Wins at Sun Vegas Casino

2011-06-03
2 players have struck it lucky at Sun Vegas Internet Casino on Monday the 30th May 2011. JK won CAD 23,373.50 playing on the video slot game Thunderstruck; CAD 21,453.50 on the 5-reel slot, Ladies Nite; and CAD 9,995.00 on the Egyptian-themed game, ISIS. Thus JK walked away with total winnings of CAD 54,822.00. Another winner, NJ, won $16,187.40 on Break Da Bank Again and $5,868.00 on Mega Moolah Summertime Progressive, giving her a total of $22,055.40. Casino Manager at Sun Vegas Casino, Austin Green, said, "Two winners in one day is what makes Sun Vegas Casino ...

Scientists identify mutations that cause congenital cataracts

2011-06-03
New research identifies genetic mutations that cause an inherited form of cataracts in humans. The study, published online June 2 by Cell Press in the American Journal of Genetics, provides new insight into the understanding of lens transparency and the development of cataracts in humans. A cataract is a clouding of the crystalline lens in the eye. Opacity of the normally transparent lens obstructs the passage of light into the eye and can lead to blindness. Congenital cataracts (CCs) are a significant cause of vision loss worldwide and underlie about one-third of the ...

For stressed bees, the glass is half empty

2011-06-03
When people are depressed or anxious, they are much more likely to see their glass as half empty than half full. In tough times, evidence of that same pessimistic outlook can be seen in dogs, rats, and birds. Now, researchers reporting online on June 2 in Current Biology, a Cell Press publication, show that bees, too, share those very same hallmarks of negative emotion. "We have shown that the emotional responses of bees to an aversive event are more similar to those of humans than previously thought," said Geraldine Wright of Newcastle University. "Bees stressed by a ...

Fraser Yachts Review of the First Quarter 2011

Fraser Yachts Review of the First Quarter 2011
2011-06-03
Following a spate of bookings during the last month, things are certainly looking rosier in terms of luxury yacht charter and the news regarding luxury yacht sales is similarly encouraging with an increase in numbers compared to the same period last year. Unfortunately the majority of these sales have been in the 24-35m categories, which represents the smaller end of the market, so while the volume is up the overall value of the market is somewhat down. Fortunately, however, over the last few days' negotiations have been completed with regard to a number of very large ...

Gladstone scientists discover drug candidate for Alzheimer's, Huntington's disease

2011-06-03
SAN FRANCISCO, CA—June 2, 2011—Scientists at the Gladstone Institutes have identified a drug candidate that diminishes the effects of both Alzheimer's disease and Huntington's disease in animal models, offering new hope for patients who currently lack any medications to halt the progression of these two debilitating illnesses. Gladstone Investigator Paul Muchowski, PhD, has identified a new compound called JM6 in experiments done in collaboration with an international team of researchers, and which are being published today in an online article in Cell. In laboratory ...

C-reactive protein levels predict breast cancer survival rates

2011-06-03
Levels of C-reactive protein (CRP) are increased in response to acute inflammation, infection and tissue damage. There are also reports that CRP levels are elevated because of cancer. New research published in BioMed Central's open access journal Breast Cancer Research shows that elevated CRP levels are predictive of a poor prognosis for breast cancer sufferers. C-reactive protein is produced by the liver, in response to infection or injury, when stimulated by the cytokine IL-6. Tumor sites are often associated with inflammation and this inflammation contributes to tumor ...

Stem cell treatment to prevent leukemia returning is a step closer, say scientists

2011-06-03
Researchers at King's College London have identified a way of eliminating leukaemic stem cells, which could lead to new treatments that may enable complete remission for leukaemia patients. An early study in mice has shown that leukaemic stem cells can be abolished by suppressing two proteins found in the body. Leukaemic stem cells sustain the disease and are likely to be responsible for relapse, so elimination of these cells is believed to be key for achieving complete remission. These encouraging findings highlight the two proteins as potential therapeutic targets ...

Revamped college science course improves student performance -- in spite of cuts

2011-06-03
Students overall performed better – and educationally disadvantaged students generally made even greater strides than everyone else – in an introductory biology course at a university where recent budget woes doubled class sizes for the course, cut lab times and reduced the number of graduate teaching assistants. The keys to success are instructors who guide learning rather than lecture, and who structure courses so students are more likely to come to class having read assignments and where they undergo intensive practice to develop critical thinking and problem solving ...

Researchers characterize epigenetic fingerprint of 1,628 people

2011-06-03
Until a decade, it was believed that differences between people were due solely to the existence of genetic changes, which are alterations in the sequence of our genes. The discoveries made during these last ten years show that beings with the same genetics like the twins and cloned animals may have different characteristics and disease due to epigenetic changes. Epigenetics involves chemical signatures that are added to DNA and proteins that package it, to regulate their activity. The more recognized epigenetic brand is DNA methylation, a process based on the addition ...

Non-independent mutations present new path to evolutionary success

Non-independent mutations present new path to evolutionary success
2011-06-03
Mutations of DNA that lead to one base being replaced by another don't have to happen as single, independent events in humans and other eukaryotes, a group of Indiana University Bloomington biologists has learned after surveying several creatures' genomes. And, the scientists argue, if "point mutations" can happen in twos, threes -- even nines – large evolutionary jumps are possible, especially when problems caused by a single point mutation are immediately compensated for by a second or third. The work appears in the latest issue of Current Biology. "A similar phenomenon ...

Study reveals how right-to-work laws impact store openings

2011-06-03
NEW YORK — June 2, 2011 — A new study by Columbia Business School Professor Paul Ingram, Kravis Professor Business, Management and senior scholar at the Jerome A. Chazen Institute for International Business at Columbia Business School; Hayagreeva Rao, Atholl McBean Professor of Organizational Behavior and Human Resources, Stanford Graduate School of Business; and Qingyuan (Lori) Yue, Assistant Professor of Management and Organization, USC Marshall School of Business, found evidence of how firms engage in regulatory arbitrage and make decisions based on a state's regulatory ...

New research: Post-exercise recovery advantages of lowfat chocolate milk

2011-06-03
WASHINGTON (June 2, 2011) – New research suggests an effective recovery drink may already be in your refrigerator: lowfat chocolate milk. Grabbing lowfat chocolate milk after a tough workout helped give both trained and amateur athletes a post-exercise training advantage, according to three new studies presented at the American College of Sports Medicine and published in the Journal of Strength and Conditioning Research this month. Athletes in the studies who had a post-exercise lowfat chocolate milk– with the right mix of carbs and high-quality protein – had improved ...

Fraser Yachts Summary - Film Festivals and Formula 1

Fraser Yachts Summary - Film Festivals and Formula 1
2011-06-03
Last weekend saw the return of motor racing to the streets of Monte Carlo and La Condamine for what is undoubtedly the sport's most prestigious and famous event, the F1 Monaco Grand Prix. This year, Fraser Yachts secured several trackside charter yachts for clients wishing to get close to the action as well as several other anchors within the bay. Following hot on the heels of the Cannes Film Festival, which drew to a close last Sunday, the weekend of the Monaco Grand Prix is widely regarded as the start of the Mediterranean yacht charter season and having experienced ...

A drug combination extends survival in refractory lung cancer patients

2011-06-03
NEW YORK CITY —Scientists have identified a drug combination, when used in advanced lung cancer patients, shows a survival advantage in patients who no longer respond to existing therapies. They found that bexarotene and erlotinib can each repress the critical cell cycle regulator: cyclin D1. The drug combination also broadened the reach to include a specific subset of patients, such as those resistant due to the presence of a ras mutation in their cancer. The study was published in the June issue of Cancer Prevention Research. "Erlotinib has been found to be most effective ...

A hot body could help ships reduce drag

2011-06-03
New research into drag reduction has the potential to help industries such shipping to reduce energy use and carbon emissions. Professor Derek Chan from the University of Melbourne's Department of Mathematics and Statistics said the research demonstrates a new way to minimise drag of fast moving projectiles in water. A collaboration between the University of Melbourne and the King Abdulla University of Science and Technology in Saudi Arabia, the research was based on the 255 year-old Leidenfrost effect. The Leidenfrost effect describes the phenomenon where a liquid ...

Higher doses of radiation in fewer treatments proved safe, effective for low-risk prostate cancer

2011-06-03
DALLAS – June 2, 2011 – In a multicenter clinical trial, UT Southwestern Medical Center researchers have found that higher doses of stereotactic radiation therapy requiring fewer treatments are safe and effective for patients with low-to-intermediate-risk prostate cancer. Results of the trial, available in the Journal of Clinical Oncology, showed that stereotactic body radiation therapy (SBRT), which delivers ultra-precise radiation, was effective in treating patients with localized prostate cancer in five 30-minute sessions every other day over two weeks. That compares ...

Silencing a deadly conversation in breast cancer

2011-06-03
While it is already known that breast cancer cells create the conditions for their own survival by communicating their needs to the healthy cells that surround them, Australian researchers have identified a new way of turning off that cellular cross talk. They have shown that a molecule known as 'hedgehog' sits at the centre of the switchboard in breast cancer, transmitting biochemical signals between the cancer cells and healthy cells. When this conversation is blocked – or hedgehog is 'silenced' – tumours shrink and stop their spread. While the finding applies ...

Adult brain requires MeCP2 for proper functioning

2011-06-03
A paper published online today in Science provides evidence that the Methyl-CpG-Binding Protein 2 (MeCP2) is required throughout life to maintain healthy brain function. The findings are reported from the Baylor College of Medicine lab of Huda Zoghbi, HHMI investigator and Director of the Jan and Dan Duncan Neurological Research Institute. Mutations in MeCP2 cause the autism spectrum disorder Rett Syndrome, and have been seen in some cases of classic autism, childhood schizophrenia and milder neuropsychiatric conditions such as anxiety and learning disabilities. Rett ...
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