Genome Research publishes online and in print today a special issue dedicated to The ENCODE (ENCyclopedia Of DNA Elements) Project, whose goal is to characterize all functional elements in the human genome. Since the completion of the pilot phase of the project in 2007, covering 1% of the genome, The ENCODE Consortium has fanned out across the genome to study function and regulation on an unprecedented scale. This special issue presents novel findings, methodologies, and resources from ENCODE that bring extensive insight to gene regulation and set the stage for future ...

(Boston) – Results of a study led by researchers at Boston University School of Medicine (BUSM) and the Veterans Affairs (VA) Boston Healthcare System indicate that the proposed changes to the diagnosis of post-traumatic stress disorder (PTSD) will not substantially affect the number of people who meet criteria for the disorder. Mark W. Miller, PhD, associate professor at BUSM and a clinical research psychologist at the National Center for PTSD at VA Boston Healthcare System served as lead author of the study, which is published online in Psychological Trauma: Theory, ...

Windows to the past, stars can unveil the history of our universe, currently estimated to be 14 billion years old. The farther away the star, the older it is — and the oldest stars are the most difficult to detect. Current telescopes can only see galaxies about 700 million years old, and only when the galaxy is unusually large or as the result of a big event like a stellar explosion. Now, an international team of scientists led by researchers at Tel Aviv University have developed a method for detecting galaxies of stars that formed when the universe was in its infancy, ...

Scientists have completed a comprehensive map of genetic mutations linked to an aggressive and lethal type of lung cancer. Among the errors found in small cell lung cancers, the team of scientists, including those at the Johns Hopkins Kimmel Cancer Center, found an alteration in a gene called SOX2 associated with early embryonic development. "Small cell lung cancers are very aggressive. Most are found late, when the cancer has spread and typical survival is less than a year after diagnosis," says Charles Rudin, M.D., Ph.D., professor of oncology at the Johns Hopkins ...

ANN ARBOR, Mich. — Aiming to cut expenses and improve care, a 2008 Medicare policy stopped paying hospitals extra to treat some preventable, hospital-acquired conditions – including urinary tract infections (UTIs) in patients after bladder catheters are placed. But a statewide analysis by the University of Michigan shows there was very little change in hospital payment due to removing pay for hospital-acquired catheter-associated UTIs. For all adult hospital stays in Michigan in 2009, eliminating payment for this infection decreased hospital pay for only 25 hospital ...

RICHLAND, Wash. – Today's light-emitting diode light bulbs have a slight environmental edge over compact fluorescent lamps. And that gap is expected to grow significantly as technology and manufacturing methods improve in the next five years, according to a new report from the Department of Energy's Pacific Northwest National Laboratory and UK-based N14 Energy Limited. "The light-emitting diode lamp is a rapidly evolving technology that, while already energy efficient, will become even more so in just a few short years," said Marc Ledbetter, who manages PNNL's solid-state ...

ANN ARBOR, Mich.—The rhetoric is relentless: America is a place of unparalleled opportunity, where hard work and determination can propel a child out of humble beginnings into the White House, or at least a mansion on a hill. But the reality is very different, according to a University of Michigan researcher who is studying inequality across generations around the world. "Especially in the United States, people underestimate the extent to which your destiny is linked to your background. Research shows that it's really a myth that the U.S. is a land of exceptional social ...

JEJU, SOUTH KOREA (September 5, 2012) — Will the tiger go the way of the passenger pigeon or be saved from extinction like the American bison? The Wildlife Conservation Society (WCS) today released a list of Asian species that are at a conservation crossroads calling for governments to take immediate action with The Three R's Approach: Recognition, Responsibility, Recovery. The list includes: the tiger, orangutans, Mekong giant catfish, Asian rhinos, Asian giant river turtles, and Asian vultures. The announcement was made at the IUCN's World Conservation Congress convening ...

Attention men: The day may be coming soon when you can take your own birth control pill with no side effects, according to a study done by a group of scientists that includes a Texas A&M University researcher. Qinglei Li, an assistant professor in Texas A&M's College of Veterinary Medicine & Biomedical Sciences, is part of a team of researchers led by Martin Matzuk at Baylor College of Medicine and James Bradner at Dana-Farber Cancer Institute who made the discovery, and their work is published in the journal Cell. Working on mice, the team found that a compound called ...

The National Human Genome Research Institute today announced the results of a five-year international study of the regulation and organization of the human genome. The project is named ENCODE, which stands for the Encyclopedia of DNA Elements. In conjunction with the release of those results, the Journal of Biological Chemistry has published a series of reviews that focus on several aspects of the findings. "The ENCODE project not only generated an enormous body of data about our genome, but it also analyzed many issues to better understand how the genome functions in ...

The most-studied mass extinction in Earth history happened 65 million years ago and is widely thought to have wiped out the dinosaurs. New University of Washington research indicates that a separate extinction came shortly before that, triggered by volcanic eruptions that warmed the planet and killed life on the ocean floor. The well-known second event is believed to have been triggered by an asteroid at least 6 miles in diameter slamming into Mexico's Yucatán Peninsula. But new evidence shows that by the time of the asteroid impact, life on the seafloor – mostly species ...

Montreal, September 5, 2012 – Being the last one picked for the team, getting left out of the clique of cool girls, having no one to sit with at lunch… For children, social exclusion can impact everything from emotional well being to academic achievements. But what does it mean for the kids doing the excluding? Is the cure a one-size-fits-all approach that requires kids to include others, regardless of the situation at hand? Not necessarily, says new research from a professor now at Concordia University. Unlike previous studies where researchers created hypothetical ...

CAMBRIDGE, MA -- Only about 1 percent of the human genome contains gene regions that code for proteins, raising the question of what the rest of the DNA is doing. Scientists have now begun to discover the answer: About 80 percent of the genome is biochemically active, and likely involved in regulating the expression of nearby genes, according to a study from a large international team of researchers. The consortium, known as ENCODE (which stands for "Encyclopedia of DNA Elements"), includes hundreds of scientists from several dozen labs around the world. Using genetic ...

Infrared data from NASA's Aqua satellite shows that Tropical Storm Leslie has been causing problems for itself. Tropical Storm Leslie has been on a slow track in the Atlantic, and because of that, the storm is kicking up cooler waters from below the ocean surface. Those cooler waters were seen in infrared imagery on Sept. 5 at 0611 UTC (2:11 a.m. EDT) taken by the Atmospheric Infrared Sounder (AIRS) instrument that flies aboard NASA's Aqua satellite. The cooler waters are responsible for Leslie's slow strengthening. Sea surface temperatures need to be at least as warm ...

Post-tropical cyclone John has been "flushed" out of existence in the eastern Pacific Ocean, and infrared NASA imagery revealed warmer cloud top temperatures and virtually no precipitation from John's remnants on Sept. 4. When NASA's Aqua satellite flew over post-tropical storm John on Sept. 4 at 21:23 UTC (5:23 p.m. EDT) the Atmospheric Infrared Sounder (AIRS) instrument revealed that cloud top temperatures in the storm had warmed over the previous 24 hours. AIRS data also showed there was one very tiny area of convection (rising air that forms the thunderstorms that ...

For years policymakers have attempted to replace Medicare's fee-for- service payment system with approaches that pay one price for an aggregation of services. The intent has been to reward providers for offering needed care in the most appropriate and cost-effective manner. But many of these programs have known pitfalls, says Stuart Altman, an economist and the Sol C. Chaikin Professor of National Health Policy at the Heller School for Social Policy and Management, Brandeis University. On Friday, Sept. 7, Altman and his Heller school colleague Robert Mechanic, will ...

NASA's Aqua satellite shows that tiny Tropical Storm Michael had some strong thunderstorms wrapped around its center and in a band of thunderstorms in its northeastern "arm" or quadrant. The Atmospheric Infrared Sounder (AIRS) instrument that flies aboard NASA's Aqua satellite captured in infrared image of Tropical Storm Michael on Sept. 5 at 0611 UTC (2:11 a.m. EDT) and noticed the strongest thunderstorms and coldest cloud top temperatures around the center of circulation and in a band of thunderstorms to the northeast of Michael's center. Those cloud top temperatures ...

Be warned, popularity may cause lung cancer, heart disease, and emphysema. New research from the University of Southern California (USC) and University of Texas finds that popular students in seven Southern California high schools are more likely to smoke cigarettes than their less popular counterparts. The study, which appears online this week in the Journal of Adolescent Health, confirms trends observed in previous USC-led studies of students in the sixth through 12th grades across the United States and in Mexico. "That we're still seeing this association more ...

Sinking through the inky ocean, it would seem that there is little light at depth: but you'd be wrong. 'In the mesopelagic realm [200 m] bioluminescence [light produced by animals] is very common', says Sönke Johnsen from Duke University, USA, explaining that many creatures are capable of producing light, yet rarely do so. But how much light do the inhabitants of the ocean floor (benthos) generate? Explaining that some bioluminescence is generated when organisms collide, Johnsen says, 'In the benthos you have a current moving over complicated ground with all the things ...

DURHAM, N.C. -- Crabs living half-a-mile down in the ocean, beyond the reach of sunlight, have a sort of color vision combining sensitivity to blue and ultraviolet light. Their detection of shorter wavelengths may give the crabs a way to ensure they grab food, not poison. "Call it color-coding your food," said Duke biologist Sönke Johnsen. He explained that the animals might be using their ultraviolet and blue-light sensitivity to "sort out the likely toxic corals they're sitting on, which glow, or bioluminesce, blue-green and green, from the plankton they eat, which ...

ROCHESTER, Minn. -- A minimally invasive procedure known as endovascular repair used for abdominal aortic aneurysms has a low rate of complications, even in high-risk patients such as those with kidney, heart or lung problems, a Mayo Clinic study shows. Researchers found that even when aneurysms ruptured, endovascular repair had lower mortality rates than open-abdominal surgery, the other treatment option. The findings are being presented at the Midwestern Vascular Surgical Society Annual Meeting, Sept. 6-8, in Milwaukee, Wis. An abdominal aortic aneurysm is a weakened ...

BALTIMORE, MD (September 6, 2012)—A new study shows that when enough bacteria get together in one place, they can make a collective decision to grow an appendage and swim away. This type of behavior has been seen for the first time in marine sponges, and could lead to an understanding of how to break up harmful bacterial biofilms, such as plaque on teeth or those found on internal medical devices like artificial heart valves. Bacteria have ways of communicating with each other, and scientists have now identified a new signaling system that, when there is a critical mass ...

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment. Their research investigating the effects of acidity on breast and pancreatic cancer cell lines revealed the importance of autophagy in acidic microenvironments and suggests that a successful treatment strategy might be based on this autophagic dependence. The study appears as the cover story for the Aug. 15 issue of Cancer Research, a publication ...

Positive American Youth, Inc. (P.A.Y. USA), chaired by Atlanta radio personality Maurice "Reec" Swiney announces the 2012 5th Annual PAY USA "PAY DAY". The yearly event which benefits metro Atlanta children & their families will be held, Saturday Sept. 29th @ Atlanta Metro College. The fun begins at 11 am and lasts until 4 pm. The purpose of the "PAY DAY" event is to promote the importance of education, healthcare, community involvement, and perseverance to urban children. "We are proud to say last years' event was very successful," ...

Crime Victims First (www.crimevictimsfirst.org) proclaims October 21, 2012 a "No Violence Day," and announces our 3rd Annual Jam for Justice Music Festival (www.jam4justice.org). This is our annual event to increase awareness and to offer a family event to celebrate all that our community does on behalf of crime victims. The event is free. The Keynote Speaker is Meg Garvin, Executive Director at the National Crime Victim Law Institute. Meg is also our 2012 Outstanding Community Service Award Winner. The music festival features Quenby and the West of Wayland Band ...