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Traveling through the volcanic conduit

2012-07-24
How much ash will be injected into the atmosphere during Earth's next volcanic eruption? Recent eruptions have demonstrated our continued vulnerability to ash dispersal, which can disrupt the aviation industry and cause billions of dollars in economic loss. Scientists widely believe that volcanic particle size is determined by the initial fragmentation process, when bubbly magma deep in the volcano changes into gas-particle flows. But new Georgia Tech research indicates a more dynamic process where the amount and size of volcanic ash actually depend on what happens afterward, ...

Powerful class of antioxidants may be potent Parkinson's treatment

2012-07-24
AUGUSTA, Ga. – A new and powerful class of antioxidants could one day be a potent treatment for Parkinson's disease, researchers report. A class of antioxidants called synthetic triterpenoids blocked development of Parkinson's in an animal model that develops the disease in a handful of days, said Dr. Bobby Thomas, neuroscientist at the Medical College of Georgia at Georgia Health Sciences University and corresponding author of the study in the journal Antioxidants & Redox Signaling. Thomas and his colleagues were able to block the death of dopamine-producing brain ...

New model of disease contagion ranks US airports in terms of their spreading influence

2012-07-24
CAMBRIDGE, Mass. -- Public health crises of the past decade — such as the 2003 SARS outbreak, which spread to 37 countries and caused about 1,000 deaths, and the 2009 H1N1 flu pandemic that killed about 300,000 people worldwide — have heightened awareness that new viruses or bacteria could spread quickly across the globe, aided by air travel. While epidemiologists and scientists who study complex network systems — such as contagion patterns and information spread in social networks — are working to create mathematical models that describe the worldwide spread of disease, ...

Researchers develop ginseng-fortified milk to improve cognitive function

2012-07-24
Amsterdam, The Netherlands, July 23, 2012 – American ginseng is reported to have neurocognitive effects, and research has shown benefits in aging, central nervous system disorders, and neurodegenerative diseases. The challenges of incorporating ginseng into food are twofold: it has a bitter taste, and food processing can eliminate its healthful benefits. Reporting in the August issue of the Journal of Dairy Science®, a group of scientists has formulated low-lactose functional milk that maintained beneficial levels of American ginseng after processing. An exploratory ...

Trial signals major milestone in hunt for new TB drugs

2012-07-24
WASHINGTON, DC/LONDON (July 23, 2012) – A novel approach to discover the first new tuberculosis (TB) combination drug regimen cleared a major hurdle when Phase II clinical trial results found it could kill more than 99 percent of patients' TB bacteria within two weeks and could be more effective than existing treatments, according to a study published today in the Lancet. These results add to a growing body of evidence that the new regimen could reduce treatment by more than a year for some patients. The findings from researchers and the non-profit TB Alliance raise hope ...

Neural precursor cells induce cell death in certain brain tumors

2012-07-24
Neural precursor cells (NPC) in the young brain suppress certain brain tumors such as high-grade gliomas, especially glioblastoma (GBM), which are among the most common and most aggressive tumors. Now researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Charité – Universitätsmedizin Berlin have deciphered the underlying mechanism of action with which neural precursor cells protect the young brain against these tumors. They found that the NPC release substances that activate TRPV1 ion channels in the tumor cells and subsequently induce the ...

Study shows why some types of multitasking are more dangerous than others

2012-07-24
COLUMBUS, Ohio - In a new study that has implications for distracted drivers, researchers found that people are better at juggling some types of multitasking than they are at others. Trying to do two visual tasks at once hurt performance in both tasks significantly more than combining a visual and an audio task, the research found. Alarmingly, though, people who tried to do two visual tasks at the same time rated their performance as better than did those who combined a visual and an audio task - even though their actual performance was worse. "Many people have this ...

Ancient alteration of seawater chemistry linked with past climate change

2012-07-24
Scientists have discovered a potential cause of Earth's "icehouse climate" cooling trend of the past 45 million years. It has everything to do with the chemistry of the world's oceans. "Seawater chemistry is characterized by long phases of stability, which are interrupted by short intervals of rapid change," says geoscientist Ulrich Wortmann of the University of Toronto, lead author of a paper reporting the results and published this week in the journal Science. "We've established a new framework that helps us better interpret evolutionary trends and climate change ...

University of Alberta's designer compounds inhibit prion infection

2012-07-24
(Edmonton) A team of University of Alberta researchers has identified a new class of compounds that inhibit the spread of prions, misfolded proteins in the brain that trigger lethal neurodegenerative diseases in humans and animals. U of A chemistry researcher Frederick West and his team have developed compounds that clear prions from infected cells derived from the brain. "When these designer molecules were put into infected cells in our lab experiments, the numbers of misfolded proteins diminished—and in some cases we couldn't detect any remaining misfolded prions," ...

Tel Aviv University research links childhood obesity to cancer risk

2012-07-24
Parents are increasingly conscious of the dangers of childhood obesity. There is a growing recognition of health problems associated with extra pounds, including the risk of diabetes, heart disease, and joint and muscle pain. New research from Tel Aviv University has revealed another significant reason for children to maintain a healthy weight. Dr. Ari Shamiss and Dr. Adi Leiba of TAU's Sackler Faculty of Medicine and the Sheba Medical Center and their fellow researchers found that obesity in adolescence, defined as a Body Mass Index (BMI) in the 85th percentile and ...

University of Tennessee Space Institute researchers develop laser technology to fight cancer

2012-07-24
Researchers at the Center for Laser Applications at the University of Tennessee Space Institute in Tullahoma have developed a technology that goes on a "seek and destroy" mission for cancerous tumors. They have harnessed the power of lasers to find, map and non-invasively destruct cancerous tumors. Christian Parigger, associate professor of physics, and Jacqueline Johnson, associate professor of mechanical, aerospace, and biomedical engineering, along with Robert Splinter of Splinter Consultants, have developed the invention. The technology uses a femtosecond laser, ...

Aspirin protects against Barrett's esophagus

2012-07-24
Aspirin use appears to reduce the risk of Barrett's esophagus (BE), the largest known risk factor for esophageal cancer, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. "The protective effect of aspirin use appears robust because the analyses suggests a dose-response relationship in which high-dose aspirin was significantly associated with decreased Barrett's esophagus risk," said Chin Hur, MD, MPH, of the Massachusetts General Hospital Institute for Technology ...

UConn researchers discover that 'red tide' species is deadlier than first thought

2012-07-24
A University of Connecticut researcher and his team have discovered that a species of tiny aquatic organism prominent in harmful algal blooms sometimes called "red tide" is even deadlier than first thought, with potential consequences for entire marine food chains. Professor Hans Dam and his research group in the school's Department of Marine Sciences have discovered that the plankton species Alexandrium tamarense contains not one but two different types of toxins, one that's deadly to large organisms and one that's deadly to small predators. "If it's killing multicellular ...

Why does vivid memory 'feel so real?'

2012-07-24
Toronto, Canada – Neuroscientists have found strong evidence that vivid memory and directly experiencing the real moment can trigger similar brain activation patterns. The study, led by Baycrest's Rotman Research Institute (RRI), in collaboration with the University of Texas at Dallas, is one of the most ambitious and complex yet for elucidating the brain's ability to evoke a memory by reactivating the parts of the brain that were engaged during the original perceptual experience. Researchers found that vivid memory and real perceptual experience share "striking" similarities ...

Mice have distinct subsystem to handle smell associated with fear

2012-07-24
PROVIDENCE, R.I. [Brown University] — A new study finds that mice have a distinct neural subsystem that links the nose to the brain and is associated with instinctually important smells such as those emitted by predators. That insight, published online this week in Proceedings of the National Academy of Sciences, prompts the question whether mice and other mammals have specially hardwired neural circuitry to trigger instinctive behavior in response to certain smells. In the series of experiments and observations described in the paper, the authors found that nerve cells ...

Survival rates for premature babies in high-level NICUs are better than previously reported

2012-07-24
Premature babies are more likely to survive when they are born in high-level neonatal intensive care units (NICUs) than in hospitals without such facilities, and this benefit is considerably larger than previously reported. The likelihood that an extremely premature baby will survive if born in a high-technology, high-volume hospital unit was already known, but the current study, the largest to date, revealed a stronger effect. Pediatric researchers who analyzed more than 1.3 million premature births over a 10-year span found that the survival benefits applied not only ...

Study finds non-disclosure of HIV serostatus common among India female sex workers

2012-07-24
(Boston) - Researchers from Boston University School of Medicine (BUSM) in partnership with Indian researchers and HIV positive networks groups, have found that in India, non-disclosure of HIV serostatus to sex partners among both HIV-infected female sex workers (FSWs) and HIV-infected clients of FSWs is exceedingly common. These findings currently appear online in the journal AIDS and Behavior. No previous studies in India specifically, and few internationally, have assessed FSWs' and male clients' disclosure of HIV status to sex partners. Disclosure of HIV serostatus ...

New species of ancient rodents hint at what could be world's oldest grasslands

2012-07-24
A paleontological team that includes scientists from the American Museum of Natural History; University of California, Santa Barbara; and Case Western Reserve University has described two ancient species of South American rodents, including the oldest chinchilla, a discovery that substantiates what might be the earliest grasslands in the world. The two new species lived near a chain of volcanoes about 32.5 million years ago in what are now the steep slopes of a river valley in the Chilean Andes. Studies of the teeth of the ancient chinchilla support evidence from other ...

New findings by GW researcher break tanning misconceptions: 'There is no such thing as a safe tan'

2012-07-24
WASHINGTON (July 23, 2012) – A new study conducted by GW School of Medicine and Health Sciences (SMHS) researchers Edward C. De Fabo, Ph.D., Frances P. Noonan, Ph.D., and Anastas Popratiloff, M.D., Ph.D., has been published in the journal Nature Communications. Their paper, entitled "Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment," was published in June 2012. "This is the first time that UV-induced melanin formation (tanning), traditionally thought to protect against skin cancer, is shown to be directly involved in melanoma ...

Clemson plant breeders roll out new oat variety

2012-07-24
CLEMSON, S.C. — Clemson University plant breeders announced a new high-yielding variety of oats. Named Graham, the new variety grows to medium height, withstands falling over (lodging), matures earlier and produces more seed than comparable varieties. "Graham has excellent seed yield potential, exceeding the Rodgers variety by 20 bushels per acre at some locations and produces a 32.2-pound bushel compared to 31.9-pound bushel for Rodgers," said Chris Ray, director of the S.C. Crop Improvement Association, which grows certified seed for sale to the public. The new ...

Research shows potential of microneedles to target therapeutics to the back of the eye

2012-07-24
Thanks to tiny microneedles, eye doctors may soon have a better way to treat diseases such as macular degeneration that affect tissues in the back of the eye. That could be important as the population ages and develops more eye-related illnesses – and as pharmaceutical companies develop new drugs that otherwise could only be administered by injecting into the eye with a hypodermic needle. For the first time, researchers from the Georgia Institute of Technology and Emory University have demonstrated that microneedles less than a millimeter in length can deliver drug molecules ...

Bloodstream scavenger inhibits clotting without increased bleeding

2012-07-24
DURHAM, N.C. – A compound that mops up debris of damaged cells from the bloodstream may be the first in a new class of drugs designed to address one of medicine's most difficult challenges -- stopping the formation of blood clots without triggering equally threatening bleeding. In a mouse study published online July 23, 2012, in the journal Proceedings of the National Academy of Sciences, Duke University Medical Center scientists report that the experimental compound called PAMAM G-3 actually prevents activation of the process that leads to the formation of dangerous blood ...

Synthetic stimulants called 'bath salts' act in the brain like cocaine

2012-07-24
CHAPEL HILL, NC – The use of the synthetic stimulants collectively known as "bath salts" have gained popularity among recreational drug users over the last five years, largely because they were readily available and unrestricted via the Internet and at convenience stores, and were virtually unregulated. Recent studies point to compulsive drug taking among bath salts users, and several deaths have been blamed on the bath salt mephedrone (4-methylmethcathinone or "meow-meow"). This has led several countries to ban the production, possession, and sale of mephedrone and ...

Public health expert David Dausey calls BPA ban 'hollow victory'

2012-07-24
The FDA says baby bottles and sippy cups can no longer contain Bisphenol-A (BPA), an endocrine disruptor that mimics estrogen. But what about the hundreds of other plastic items, from water bottles to dental sealants, containing BPA? The FDA didn't go far enough, said Mercyhurst University Public Health Department Chair Dr. David Dausey. Dausey addresses the FDA's recent BPA ban in his latest vlog, The Dausey File: Public Health News Today. BPA has been associated with a wide range of health problems from metabolic disease to reproductive health defects. Dausey said ...

Rise in temperatures and CO2 follow each other closely in climate change

2012-07-24
The greatest climate change the world has seen in the last 100,000 years was the transition from the ice age to the warm interglacial period. New research from the Niels Bohr Institute at the University of Copenhagen indicates that, contrary to previous opinion, the rise in temperature and the rise in the atmospheric CO2 follow each other closely in terms of time. The results have been published in the scientific journal, Climate of the Past. In the warmer climate the atmospheric content of CO2 is naturally higher. The gas CO2 (carbon dioxide) is a green-house gas that ...
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