Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have conducted the first comprehensive census of human cells' export workers. In a study published online today in Nature Cell Biology, they found an unexpected variety of genes involved in transporting molecules to the cell membrane and beyond. Using a combination of genetics and sophisticated microscopy, Rainer Pepperkok and colleagues systematically silenced each of our 22 000 genes, and observed to what extent this affected the cell's ability to transport a protein. They found that ...

Among the founding fathers of the biotechnology industry, Roberto Crea, PhD., founder and CEO of CreAgri Inc., is internationally acknowledged for the role he played in the successful establishment and growth of Genentech, Inc.--as one of the first four scientific founders of the legendary biotech company—and for his pioneering role in the production of many rDNA protein drugs from bacteria. Among other innovations, Dr. Crea is the inventor of the synthetic DNA process that led to the discovery of the first recombinant human insulin, Humulin , and many other pharmaceutical ...

Researchers at Universitat Autònoma de Barcelona (UAB), the Spanish National Research Council (CSIC) and the University of Barcelona (UB) have developed a multitarget molecule, ASS234, which according to the results of in vitro studies conducted, inhibits the aggregation of the ß-amyloid protein, involved in Alzheimer's disease. At the same time, ASS234 stimulates the cholinergic and monoaminergic transmission, key factors involved in the cognitive function. In addition, ASS234 is able to cross the blood–brain barrier with an elevated multipotent profile designed on basis ...

A new facade rendering has already been drafted and in addition to a new beautiful exterior, the landlord is welcoming and friendly. Jack Intrator, Retail & Restaurant Leasing Specialist, explains, "You have all the necessary components to bring in a new and fresh tenant mix to a center that was dated at best." A crucial ingredient to a new tenant mix is a landlord that is committed to creating an asset for the future, not just looking at the bottom line of that specific day. This means you have a landlord that is prepared to invest in his tenancy, providing ...

This press release is available in Spanish. VIDEO: Research at Carlos III University in Madrid is developing an algorithm, based on ants’ behavior when they are searching for food, which accelerates the search for relationships among elements that... Click here for more information. One of the main technical questions in the field of social networks, whose use is becoming more and ...

Nationally acclaimed cookbook author and food editor Susan Wyler, MPH, RD, LDN, has recently opened Triangle Nutritional Wellness as a complementary practice at Chapel Hill Doctors Integrative Health Center. A registered dietitian and licensed nutritionist accredited by the Academy of Nutrition and Dietetics, Wyler will work with the center to provide traditional and integrative medical nutrition therapy and dietary support to patients in the Triangle area. As one of its first unique services, she is working with the center to provide a Spring Wellness Package to help people ...

In celebration of the 2012 MTV Movie Awards sustainable film and television producer Debbie Durkin hosted the "Rockn Rolla" MTV Movie Awards Eco Lounge presented by Gibson Guitar to benefit Music Saves Lives . The interactive daytime event pampered guests with eco-luxury lifestyle brands and services at the breathtaking historic Pickford Mansion where the Oscar-winning Best Picture "The Artist" was filmed. Presenting sponsor Gibson Guitar featured live acoustic performances while promoting blood drives for the American Red Cross and Music Saves Lives. ...

It's raining cats and dogs and even the short run out to the car leaves your vision obscured by rain on your spectacles. There might soon be no need to reach for a cloth to wipe them off. If the surface of the lens resembled that of a lotus leaf, the drops would all fall off by themselves. The practicality of such self-cleaning surfaces is not limited to eyewear. Corrosion coatings would put up a better fight against rust without the tiny puddles of water that tend to collect on top of them. But exactly what characterizes surfaces that do the best job of cleaning themselves? ...

"On My Behalf" details the misadventures of a naïve Vietnamese girl pursuing her dream of becoming a successful writer. As she navigates through early adulthood, she finds that balancing between staying true to her dreams and settling for an unremarkable life challenges every fiber of her being. Helen Doan is a Vietnamese-American writer born in Kien Giang, Vietnam. She arrived in San Jose, California in 1986 where she grew up. Doan self-published a book of poetry in 2002 and has been writing feature-length screenplays for ten years, while keeping a journal ...

Simply-Bookkeeping Inc, a professional audit ready bookkeeping, financial management and tax firm based in Houston, TX proudly announces its immediate availability to entertainment artists, musicians, film and stage performers, and other industry professionals to assist them with their audit ready bookkeeping and business management needs. "The Entertainment businesses face unique bookkeeping challenges that many mainstream bookkeeping and financial management firms are unable or unwilling to meet. "At Simply-Bookkeeping we constantly strive to evolve our services ...

It is not very fun to ride a bicycle on a street plastered with cobblestones. At least the bike has a saddle seat filled with silicone. That lessens the shocks and bumps, and counteracts some of the annoying vibrations. In a professional's eyes, the material in the saddle is an "elastomer" – a material that is yielding and malleable, like a rubber band. Engineers at the Fraunhofer Institute for Structural Durability and System Reliability LBF in Darmstadt are now working on the next generation: They are designing components made of elastomers that actively respond to unwanted ...

Reno, Nevada attorney Lee T. Hotchkin has launched a new Website for his practice at 100 West Liberty Street, Suite 820 in Reno, Nevada. The Website, HotchkinLaw.com provides consumers with information about Mr. Hotchkin's experience as a trial lawyer with an emphasis as a Reno personal injury lawyer, Nevada criminal defense lawyer, Truckee family lawyer and Carson city civil law attorney. With up to date news and company information, the new web site acts as an invaluable tool for Nevada and California residents interested in finding a lawyer to match their needs. As ...

CHICAGO, June 4, 2012 – New data reveals that women treated with radiation to the chest for childhood cancer have a high risk of developing breast cancer similar to that of women with BRCA1/2 mutations. The study, led by Memorial Sloan-Kettering Cancer Center biostatistician Chaya Moskowitz, PhD, was presented today at the 2012 American Society of Clinical Oncology (ASCO) Annual Meeting. "Previous studies have shown that women treated with radiation to the chest for childhood cancer have an increased risk for breast cancer, but ours is the first to demonstrate that their ...

Cells do more than just sit there, one next to the other – they constantly exchange information. It has been shown recently that they communicate via complex messages, wrapped in a small vesicle, and as if it was a letter in an envelope. These vesicles are called exosomes. Exosomes: small communication channels with a possible role in cancer Pre-clinical studies indicate that exosomes might contribute to tumor development, influencing tumor angiogenesis, immune escape and metastasis. As a result one is developing therapeutic anti-tumor strategies, targeting the formation ...

Dr. Peter Bray, Plastic and Reconstructive Surgeon is using a NEW technology to re-contour, sculpt and shape the backside, and augment the butt; BodyTite, is a Radio-Frequency Assisted Liposuction (RFAL) that's revolutionizing body contouring offering up to eight times the skin and connective tissue tightening of traditional liposuction. AS we age or lose a lot of weight our skin loses it's elasticity. For patients with skin laxity and/or stretch marks along with fat deposits using BodyTite will firm their body and decrease the risk of post-liposuction skin laxity. Compared ...

The yeast Dekkera bruxellensis plays an important role in the production of wine, as it can have either a positive or a negative impact on the taste. Researchers at Lund University in Sweden, among others, have analyzed the yeast's genome sequenced by the US Department of Energy Joint Genome Institute, giving wine producers the possibility to take control of the flavour development of the wine. Yeasts are an important ingredient in the production of various types of food, for example wine, and they make a major contribution to the taste. One of these yeasts is Dekkera ...

Puchstein Promotions, long known as one of the premier antique show promoters in the country, is expanding its list of highly successful South Florida shows with the introduction of two new shows - the Vero Beach Antiques and Vintage Show! Don't miss either of these 2 exciting and innovative shows, August 17,18,19 and October 26,27,28 at the Indian River County Fairgrounds. The extremely popular Vero Beach Winter Antiques Extravaganza has consistently drawn huge crowds of avid antique shoppers and attracts high quality dealers from across the US and Canada. Now, Kay ...

Cleveland, June 4, 2012 – A Cleveland Clinic study has detected significant changes in the electroencephalogram (EEG) brain activity patterns of patients receiving chemotherapy. The study may give scientific evidence of a condition commonly referred to as "chemobrain" – the fogginess that many patients experience while on chemotherapy. Patients with chemobrain often report short-term memory problems and difficulty concentrating. "The EEG study demonstrated a higher amplitude, or more brain activity in women, during chemotherapy that particularly went up after doing ...

Researchers from North Carolina State University have developed a technique to efficiently divide the bandwidth of the wireless spectrum in multi-hop wireless networks to improve operation and provide all users in the network with the best possible performance. "Our objective is to maximize throughput while ensuring that all users get similar 'quality of experience' from the wireless system, meaning that users get similar levels of satisfaction from the performance they experience from whatever applications they're running," says Parth Pathak, a Ph.D. student in computer ...

Snaidero Middle East, home furniture supplier and manufacturer, will display Italian home furniture at Booth # A50, 'Interior' pavilion, during Project Lebanon 2012. The international construction trade exhibition for Lebanon and the Middle East will take place from 5 - 8 June 2012 at Beirut International Exhibition & Leisure Center (BIEL), in Beirut, Lebanon. Snaidero Middle East booth visitors can view kitchens by Snaidero Italy and doors by Barausse Italy, as well as electronic home appliances from Snaidero Middle East distributor in Lebanon, Abdul Rahim Diab ...

(WASHINGTON, June 4, 2012) – Results from a study published online today in Blood, the Journal of the American Society of Hematology (ASH), demonstrate that inclusion of carfilzomib, a novel targeted therapy for multiple myeloma, in combination with lenalidomide and low-dose dexamethasone, resulted in complete or near complete remission in a majority of patients with newly diagnosed multiple myeloma. Multiple myeloma is cancer of the plasma cells, the white blood cells in the bone marrow that normally produce infection-fighting antibodies. Myeloma tumor cells overproduce ...

About 75 percent of children with leukemia who take chemotherapy face life-threatening heart problems as they age, but an international study led by a University of Rochester Medical Center investigator shows that giving a cardio-protective drug during cancer treatment may prevent the damage. Researchers and physicians will debate how to make young cancer patients and their families aware of the risks of heart damage, and the best ways to manage the risks, in a special session today at the American Society of Clinical Oncology (ASCO) meeting in Chicago. Led by Barbara ...

CallPro CRM announces its ability to integrate with QuickBooks, both the enterprise and cloud-based versions. QuickBooks is the most popular accounting software used by the U.S. SMB market. By enabling customers to integrate their CallPro CRM system with QuickBooks, CallPro CRM provides significantly added value. Peter Connell, CEO of CallPro CRM says, "Many of our current clients are small to medium businesses. Since QuickBooks is so popular with these businesses we wanted to make sure we provided this functionality with CallPro CRM. Also, we hope to attract Intuit ...

Jointly released by ESRF - TU München and Synchrotron SOLEIL Scientists have developed an X-ray imaging method that could drastically improve the contrast of computed tomography (CT) scans whilst reducing the radiation dose deposited during the scan. The new method is based on the combination of the high contrast obtained by an X-ray technique known as grating interferometry with the three-dimensional capabilities of CT. It is also compatible with clinical CT apparatus, where an X-ray source and detector rotate continuously around the patient during the scan. The results ...

Dr. Marina Kostina and Dr. William LaGanza, online education experts, have released their first book together, The Golden Climate in Distance Learning, which promises to be unlike any previous books on distance learning. Early reviews have been positive, noting that the book is well researched, engaging, and ideal for serious online instructors and trainers. The Golden Climate in Distance Learning addresses an essential dimension for distance learning teachers and trainers: How to BE with your students and trainees so as to increase their connectivity, engagement, enjoyment, ...