ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives a substantial reduction in lung metastases, according to a study published June 8 in the Journal of The National Cancer Institute. Several ADAMs are known to be found in tumors and are linked with both tumor growth and cancer progression in humans. While ADAM28 is overexpressed in both breast and non-small cell lung cancers, the mechanism of ADAM28-mediated ...

American Society for Radiation Oncology (ASTRO) Chairman Leonard Gunderson, MD, MS, FASTRO, will testify before the House Committee on Energy and Commerce Subcommittee on Health today on provisions of the Consistency, Accuracy, Responsibility, and Excellence in Medical Imaging and Radiation Therapy Act of 2011 (CARE Act) related to training and credentialing for medical imaging and radiation therapy technologists. ASTRO strongly supports immediate passage of the CARE Act, which sets needed education and certification standards for radiation therapists, medical physicists ...

Two scientists are challenging the currently accepted norms of biofuel production. A commentary published today in GCB Bioenergy reveals that calculations of greenhouse gas (GHGs) emissions from bioenergy production are neglecting crucial information that has led to the overestimation of the benefits of biofuels compared to fossil fuels. The critique extends to the Life Cycle Analysis models of bioenergy production. Life Cycle Analysis (LCA) is a technique used to measure and compile all factors relating to the production, usage, and disposal of a fuel or product. The ...

Certain proteins, such as 14-3-3, conserve their basic functions of cell cycle control in diverse organisms, from worms to humans. In a study led by Julián Cerón and Simó Schwartz Jr, researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Research Institute of Vall d'Hebron (VHIR) respectively, have described germ line functions of par-5, which is one of the two 14-3-3 proteins existing in Caenorhabditis elegans, worms used as experimental model in genetic studies. The overexpression of the 14-3-3 proteins is related to the resistance of tumors to ...

Leslie Shepherd Manager, Media Strategy Phone: 416-864-6094 shepherdl@smh.ca St. Michael's Hospital Inspired Care. Inspiring Science. www.stmichaelshospital.com Follow us on Twitter: http://www.twitter.com/stmikeshospital ...

Miami Beach, Fla., June 8, 2012: Piramal Imaging SA, a subsidiary of Piramal Healthcare Limited [NSE: PIRHEALTH, BSE: 500302], will present data on several compounds from its molecular imaging portfolio at the Society of Nuclear Medicine's 59th annual meeting in Miami Beach, Fla., from June 9 - 13. Data from five florbetaben studies will be featured, including results from a pivotal Phase III trial which will provide the basis for regulatory submission later this year. Earlier this spring, Piramal Imaging was formed through the acquisition of worldwide rights to the molecular ...

This press release is available in German.Evolution by definition is cold and merciless: it selects for success and weeds out failure. It seems only natural to expect that such a process would simply favour genes that help themselves and not others. Yet cooperative behaviour can be observed in many areas, and humans helping each other are a common phenomenon. Thus, one of the major questions in science today is how cooperative behaviour could evolve. Scientists from the Max Planck Institute of Evolutionary Biology in Plön, Harvard University, and the University of Amsterdam ...

Imagine a world without man-made climate change, energy crunches or reliance on foreign oil. It may sound like a dream world, but University of Tennessee, Knoxville, engineers have made a giant step toward making this scenario a reality. UT researchers have successfully developed a key technology in developing an experimental reactor that can demonstrate the feasibility of fusion energy for the power grid. Nuclear fusion promises to supply more energy than the nuclear fission used today but with far fewer risks. Mechanical, aerospace and biomedical engineering professors ...

EAST LANSING, Mich. — Scanning smartphones, tablets and laptops is as much a part of vacations as slathering on sunscreen, according to a Michigan State University study. The results, which will appear in the forthcoming issue of Annals of Tourism Research, show that easy online access and ubiquitous personal devices have made the digital divide disappear, even for folks on holiday. "Not that long ago, travelers would need to find a payphone or send postcards to brag about their vacations. Now they just log on and send photos and text," said Christine Vogt, MSU professor ...

Just in time for summer, Nutrilys Del Mar in San Diego is thrilled to introduce NUTRICOSMET, a new generation of natural and organic anti-aging skincare supplements for summertime. While it's time for some fun in the sun, being outdoors for extended periods of time may cause harsh side effects on the skin. But with the NUTRICOSMET daily dietary supplement program, beauty is enhanced especially during the summer months. The NUTRICOSMET marine-based supplements, clinically tested in French and Swiss clinics since 1995, offer a proven method to promote healthier and ...

AMHERST, Mass. – Smooth wrinkles and sharply crumpled regions are familiar motifs in biological and synthetic sheets, such as plant leaves and crushed foils, say physicists Benny Davidovitch, Narayanan Menon and colleagues at the University of Massachusetts Amherst, but how a featureless sheet develops a complex shape has long remained elusive. Now, in a cover story of the journal, Proceedings of the National Academy of Sciences, the physicists report that they have identified a fundamental mechanism by which such complex patterns emerge spontaneously. Davidovitch ...

Men will always want to look and feel great for the amazing formal events that will take place throughout their lifetime. From a high school dance to an exciting wedding, there is never any reason for a man to cut any corners when it comes to the perfect outfit. For those that would like to be able to buy these tuxedos with confidence in their purchase, MegaTuxedos.com, leading online retailers for all men's, boy's, prom, and wedding tuxedos is now offering a 100 percent satisfaction guarantee on all of their outfits. Finding the correct men's tuxedos can be a difficult ...

Boulder, Colo., USA - Analysis of the water content of hydrous minerals in martian meteorites shows that Mars' interior is as wet or even wetter than Earth's mantle; detailed examination of well-preserved organic structures in Ediacaran specimens illustrates the "dawn of skeletogenesis"; a study of stromatolites in Nevada suggests that complex ecological phenomena such as reef-building began sooner than previously thought; and new findings regarding coral reef systems call for a "re-think" of prevailing models of reef growth dynamics. Highlights are provided below. GEOLOGY ...

When it comes to maintaining a successful business in today's financial climate, it is more important than ever for companies to keep a very close eye on exactly how their advertising and marketing budgets are being used. For those that would like to ensure that every dollar is being invested wisely, website design and optimization is one of the leading choices, but not every SEO company can offer the unparalleled results that a company will need. In order to allow businesses from all industries the chance to keep ahead of the competition, one trusted Los Angeles SEO firm, ...

Closing the academic gaps in performance among students from diverse backgrounds is a challenge for schools and a mandate from the government. The No Child Left Behind Act of 2001 has prompted schools and school districts to re-examine elements that impact student achievements. A study completed by a recent graduate from University of Houston's Executive Education Doctorate in Professional Leadership suggests that African-American students do not necessarily fare better when taught by African-American teachers. The study examined the impact of African-American ...

A team led by the University of Colorado Boulder looking for organisms that eke out a living in some of the most inhospitable soils on Earth has found a hardy few. A new DNA analysis of rocky soils in the Martian-like landscape on some volcanoes in South America has revealed a handful of bacteria, fungi and other rudimentary organisms called archaea, which seem to have a different way of converting energy than their cousins elsewhere in the world. "We haven't formally identified or characterized the species," said Ryan Lynch, a CU-Boulder doctoral student involved in ...

When an individual has a bright and vibrant smile, they will be able to enjoy a level of confidence unlike anything else in the world. Unfortunately, nearly everything from the foods that one eats to daily wear and tear that take place throughout the years can lead to a discoloration of one's teeth. In order to allow locals to once again be able to smile with confidence, one trusted Encino dentist, Dr. Ray Partovy, is now offering huge discounts on the most advanced whitening treatment in the world, Zoom whitening. You can visit BestDentistinEncinoCA.com for more information. The ...

DETROIT — A Wayne State University School of Medicine study has found that an overwhelming majority of African-American patients with hypertension also suffered hidden heart disease caused by high blood pressure even though they displayed no symptoms. The study – "Subclinical Hypertensive Heart Disease in African-American Patients with Elevated Blood Pressure in an Inner-City Emergency Department" – was conducted by Phillip Levy, M.D., M.P.H., associate professor of Emergency Medicine, and was recently published online in Annals of Emergency Medicine. Nine of every ...

A sidewalk shed collapsed on a 72-year old woman while she was walking on W. 23rd St., reported the New York Daily News (6/1/2012). She was hit by falling wood and metal, but escaped the New York scaffold collapse with only a broken leg. http://www.nydailynews.com/new-york/scaffolding-collapse-injures-woman-72-chelsea-article-1.1087932#ixzz1wZjxKcVE At the time of the New York construction accident, the scaffolding was being dismantled, said the tabloid. A neighborhood resident said in the tabloid, the workers had set up cones around the area to keep pedestrians ...

Researchers at Moffitt Cancer Center have developed and tested in mice a synthetic vaccine and found it effective in killing human papillomavirus-derived cancer, a virus linked to cervical cancers among others. The research was published in a recent issue of Cancer Immunology, Immunotherapy. "Vaccines for cancer can be good alternatives to conventional therapies that result in serious side-effects and are rarely effective against advanced disease," said Esteban Celis, M.D., Ph.D., senior member and professor in Moffitt's Immunology Program. "The human papillomavirus, ...

In a criminal case, prosecutors have enormous resources available, including police investigators to conduct in-depth interviews and research, extensive databases, and facilities and staff to analyze evidence with sophisticated (but not infallible) laboratory testing and analysis. In 1963, the U.S. Supreme Court established the Brady Rule to level the playing field for defendants in criminal cases. Brady requires prosecutors to disclose any evidence they discover that is favorable to the defendant - but all too often, prosecutors fail to comply, citing their duty to ...

The Tropical Rainfall Measuring Mission satellite called TRMM measures how much rain can fall per hour in storms. Between June 6 and 7, TRMM noticed the rainfall rate within Tropical Depression Kuena had lessened. A tropical storm called Kuena formed in the southwest Indian Ocean east of Madagascar on June 6, 2012. This is a little unusual because the tropical cyclone season in that area normally ends on May 15, although two tropical storms formed in the north Atlantic this year before that season even officially started, so tropical cyclones seem to be ignoring the calendar ...

Over a lifetime, up to half of all women will develop some degree of pelvic organ prolapse, or POP, due to weakened vaginal muscles. The condition, which can allow pelvic organs to sag, is usually mild; only about one in 50 women will experience troublesome symptoms. In more serious cases of POP, doctors may recommend surgical treatment. More than 75,000 women a year receive a vaginal mesh implant during surgery. But complications from vaginal mesh include pain, infections and bleeding, which have proven to be much more frequent than expected. FDA Investigation ...

All too often the news includes a report that a tanker truck or 18-wheeler has crashed on a Texas highway. For example, in late March the driver of a gasoline tanker truck died when his truck rolled over and caught fire after a collision with a car. The occupants of the car were hospitalized in serious condition. Environmental quality officials had to deal with the spilled contents of the tanker, and the road was heavily damaged and required repair. Such sobering stories could become more common as vehicle traffic increases on Texas roads due to a huge boom in oil production ...

(Santa Barbara, Calif.) –– Working with researchers at the University of Pittsburgh and the Cincinnati Children's Hospital, anthropologists at UC Santa Barbara have found high levels of beneficial omega-3 fatty acids in the breast milk of economically impoverished Amerindian woman as compared to women in the United States. Their research appears in the current issue of the journal Maternal and Child Nutrition. The study compared breast milk fatty acid composition in U.S. and Tsimane women. The Tsimane live in Amazonian Bolivia, and eat a diet consisting primarily of locally ...