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Travelzest plc Releases Pre-Close Trading Update

2011-01-16
Travelzest provides pre-close trading review and update on the group's restructuring initiatives ahead of its preliminary results for the year ending 31 October 2010, due for release in late January 2011. The Board of Travelzest has announced that it anticipates the underlying trading for the year will be in line with Board expectations. The group, both in Canada and the UK, has performed well in difficult economic markets with an overall 10% increase in departures for summer 2010. Advance bookings for winter 2010/11 departures are up 15% (compared to corresponding ...

Topshop Reveals the Looks of Spring Summer 2011

2011-01-16
Topshop has launched four new looks for Spring Summer 2011 with its Snake Valley, Swedish Summer, New Age Constellation and Graduation collections. Snake Valley is inspired by the 70s 'Gypsy Rocker' character embodied by Jimi Hendrix and Lenny Kravitz. Tough elements like snake prints, python leather, and battered biker boots are mixed with Navaho flourishes, including fringing, feathers and tapestry detailing. Sleeves are billowing and fluted, balancing the shape of a high-waist skinny leather trouser or hotpant. A blanket poncho features Aztec intarsia knits, whilst ...

Survival Guide For Snow Pros, An Effective Resource For Those Who Like To Enhance Their Career In The Ski Industry -Winter Pro File

2011-01-16
Being a ski instructor and making money as a ski instructor are not all that easy. There several challenges that every one that likes to venture into this field and establish a career should know so that they can be well prepared to meet those challenges. Though taking a ski job may look like a cool thing to do and an easy way to make money, there are many practical difficulties that need to be effectively met. The eBook "Survival Guide For Snow Pros" comes as a highly resourceful manual for those who want to take a job as a ski instructor. This eBook is a complement of ...

Researchers report on the early development of anti-HIV neutralizing antibodies

2011-01-15
New findings are bringing scientists closer to an effective HIV vaccine. Researchers from Seattle Biomedical Research Institute (Seattle BioMed), Vanderbilt University and the Ragon Institute of MGH, MIT and Harvard report findings showing new evidence about broadly-reactive neutralizing antibodies, which block HIV infection. Details are published January 13 in the open-access journal PLoS Pathogens. According to author Leo Stamatatos, Ph.D., director of the Viral Vaccines Program at Seattle BioMed and a major stumbling block in the development of an effective vaccine ...

Home dialysis effective for kidney patients after transplant fails

2011-01-15
TORONTO, Ont., Jan. 13, 2011—Patients who must return to dialysis after a kidney transplant failure survive just as well on home dialysis as hospital dialysis, but few choose that option, according to new research by Dr. Jeffrey Perl, a nephrologist at St. Michael's Hospital. Despite medical advances, transplanted kidneys don't last a lifetime and an increasing number of patients return to dialysis. These patients are at higher risk for complications and death than other dialysis patients because of such things as their exposure to immunosuppressive drugs and the length ...

NASA's Aqua Satellite sees tropical potential in system 94P

NASAs Aqua Satellite sees tropical potential in system 94P
2011-01-15
The last thing that Queensland, Australia needs is more rainfall after the record-breaking flooding that has been occurring there in the last two months. Now, NASA's Aqua satellite has noticed a low pressure area with signs of tropical development in the Coral Sea ( part of the South Pacific Ocean Basin), between Papua New Guinea and Australia's East Coast. When NASA's Aqua satellite passed over System 94P on January 13, 2011 at 0353 UTC, the Atmospheric Infrared Sounder (AIRS) instrument captured an infrared image of the low's cloud temperatures. The AIRS cloud temperatures ...

NASA satellites dissect Tropical Storm Vania's clouds and rainfall

NASA satellites dissect Tropical Storm Vanias clouds and rainfall
2011-01-15
NASA's Tropical Rainfall Measuring Mission (TRMM) and Aqua satellites are providing valuable information to forecasters about Tropical Storm Vania's clouds and rainfall as the system continues to impact Vanuatu and New Caledonia in the South Pacific. Using precipitation radar, infrared and visible technology, the two NASA satellites provided rainfall rates, cloud heights and temperatures. The TRMM satellite had a very good daytime look at tropical cyclone Vania in the South Pacific Ocean near Vanuatu on January 12, 2011 at 0435 UTC (11:35 p.m. EST Jan. 11). Top wind ...

Putting the dead to work

Putting the dead to work
2011-01-15
Conservation paleobiologists--scientists who use the fossil record to understand the evolutionary and ecological responses of present-day species to changes in their environment--are putting the dead to work. A new review of the research in this emerging field provides examples of how the fossil record can help assess environmental impacts, predict which species will be most vulnerable to environmental changes, and provide guidelines for restoration. The literature review by conservation paleobiologists Gregory Dietl of the Paleontological Research Institution and Cornell ...

Stanford researcher uses living cells to create 'biotic' video games

Stanford researcher uses living cells to create biotic video games
2011-01-15
VIDEO: Stanford physicist Ingmar Riedel-Kruse has begun developing "biotic games " involving paramecia and other living organisms. He hopes the games lead to advances in education and crowd-sourcing of laboratory research while... Click here for more information. Video game designers are always striving to make games more lifelike, but they'll have a hard time topping what Stanford researcher Ingmar Riedel-Kruse is up to. He's introducing life itself into games. Riedel-Kruse ...

Study provides molecular rationale for combining targeted agents to treat breast cancer

2011-01-15
COLUMBUS, Ohio – A new study by Ohio State University cancer researchers provides a rational for treating breast cancer by combining two kinds of targeted agents, one that inhibits an overactive, cancer-causing pathway in cancer cells and one that reverses changes that silence genes that normally prevent cancer. Both types of agents are currently available and being evaluated individually in clinical trials, the researchers note. The findings, published online in the journal Cancer Research, show that abnormal activation of the PI3K/AKT signaling pathway leads to the ...

Earth's hot past: Prologue to future climate?

Earths hot past: Prologue to future climate?
2011-01-15
The magnitude of climate change during Earth's deep past suggests that future temperatures may eventually rise far more than projected if society continues its pace of emitting greenhouse gases, a new analysis concludes. The study, by National Center for Atmospheric Research (NCAR) scientist Jeffrey Kiehl, will appear as a "Perspectives" article in this week's issue of the journal Science. The work was funded by the National Science Foundation (NSF), NCAR's sponsor. Building on recent research, the study examines the relationship between global temperatures and high ...

More intensive methods needed to identify TB in HIV-prone populations

2011-01-15
Identifying tuberculosis patients in Africa using passive methods is leaving many cases undiagnosed, according to researchers from the Netherlands, Kenya and the United States, who studied case detection methods in HIV-prone western Kenya. Tuberculosis (TB) occurs commonly in men and women with HIV, but in these patients TB can be more difficult to detect. The findings were published online ahead of the print edition of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "Limited information exists on the prevalence of tuberculosis ...

Mandatory menu labeling didn't change behavior at 1 fast food chain

2011-01-15
DURHAM, NC and KING COUNTY, WA – An effort in King County, Washington, to add nutrition facts labeling to fast food menus had no effect on consumer behavior in its first year. As part of a comprehensive effort to stem the rise in obesity, the county, which includes Seattle and environs, imposed a mandatory menu labeling regulation on all restaurant chains with 15 or more locations beginning in January, 2009. Restaurants had to disclose calorie information at the point of purchase. Researchers from Duke-National University of Singapore (NUS) Graduate Medical School ...

Speeding up E. coli detection

2011-01-15
A simple, automated method of tracking E. coli uses a laser to detect and monitor the microbe in potentially contaminated bodies of water or waterways. The technique described this month in the International Journal of Computational Biology and Drug Design could reduce the incidence of waterborne disease outbreaks. Microbial contamination of water is a worldwide environmental and health problem. Water related diseases are the leading causes of illness and death in the world. The impacts of water quality on public health and economy are highly significant as evidenced ...

Warming climate means red deer rutting season arrives early

2011-01-15
Wild red deer on the Isle of Rum, which were featured in the BBC TV series Autumnwatch, are rutting earlier in the year, a study shows. Scientists believe the annual rutting season on the Isle of Rum could be changing because of warming spring and summer temperatures. The study shows that the rutting and calving seasons are now up to two weeks earlier on average compared with 30 years ago. The research was based on a 38-year study of the ecology of red deer on the Isle of Rum and used annual records of breeding success in more than 3,000 individually recognisable ...

Heavy metals and pesticides threaten a Huelva wetland

Heavy metals and pesticides threaten a Huelva wetland
2011-01-15
The Estero de Domingo Rubio wetland, located near the Marismas del Odiel Natural Area in the Huelva estuary, is regionally, nationally and internationally protected thanks to its ecological value. However, its tributary rivers and the Ría de Huelva estuary pump manmade pollutants into it, which could affect its water quality and ecosystem. Industrial activity, accumulations of dangerous waste, the expansion of farming, and excessive extraction of sand and gravel for the construction industry are the leading threats to the Estero de Domingo Rubio wetland, the tidal system ...

Tractors rolling over is top cause of agricultural deaths

Tractors rolling over is top cause of agricultural deaths
2011-01-15
The people in Spain at greatest risk of suffering farming accidents are those aged over 65, followed by people under 16 and people from outside the agricultural sector. These are the results of a study by the Public University of Navarre (UPNA), which shows that most of these deaths are due to people being crushed by tractors. "Aside from recognised farming workers, other employees die in this sector and these deaths are not recorded. Our objective was to compare the real and official data on fatal farming accidents and to classify the most commonly associated risks", ...

Bioactive compounds in berries can reduce high blood pressure

2011-01-15
Eating blueberries can guard against high blood pressure, according to new research by the University of East Anglia (UEA) and Harvard University. High blood pressure – or hypertension – is one of the major cardiovascular diseases worldwide. It leads to stroke and heart disease and costs more than $300 billion each year. Around a quarter of the adult population is affected globally – including 10 million people in the UK and one in three US adults. Published next month in the American Journal of Clinical Nutrition, the new findings show that bioactive compounds in ...

Dramatic ocean circulation changes revealed

Dramatic ocean circulation changes revealed
2011-01-15
The unusually cold weather this winter has been caused by a change in the winds. Instead of the typical westerly winds warmed by Atlantic surface ocean currents, cold northerly Arctic winds are influencing much of Europe. However, scientists have long suspected that far more severe and longer-lasting cold intervals have been caused by changes to the circulation of the warm Atlantic ocean currents themselves. Now new research led by Cardiff University, with scientists in the UK and US, reveals that these ocean circulation changes may have been more dramatic than ...

Interactive window shopping

Interactive window shopping
2011-01-15
A woman passing by the window display is captivated and asks her companion "Isn't the leather bag chic?" "Which one do you mean? There are so many of them." The woman points to one of the bags and as if by magic the luxurious purse appears on a display behind the shop window. Then she points to a button and the designer object rotates on the screen. "So that's what it looks like from the back." The woman passing by is impressed. She makes another gesture to zoom the bag towards her letting her to see every detail. This particular shopping experience is courtesy of new ...

Measles virus plays role in Paget's disease of bone, Pitt-led team says

2011-01-15
PITTSBURGH, Jan. 14 – A gene from the measles virus plays a key role in the development of Paget's disease of bone, according to a team of researchers led by the University of Pittsburgh School of Medicine. Their findings, recently published in Cell Metabolism, confirm a long-held speculation that the childhood infection is an environmental trigger for the disease and reveal how the viral gene contributes to the development of its characteristic bone lesions. "Our earlier work showed that bone cells called osteoclasts in about 70 percent of these patients contain a certain ...

Learning while driving

Learning while driving
2011-01-15
The days are long gone when all you needed to be a truck driver was a heavy goods vehicle license and the ability to read a map. Nowadays it is a skilled occupation which requires lots of qualifications. Modern truck drivers have to operate electronic devices, adapt their routes expertly to the given traffic and loading situation, know how to drive fuel-efficiently, be up to date with statutory regulations and monitor the safety of their load. Then there is all the complex legislation introduced at EU level. What's more, drivers who make trips to other countries also need ...

Enhanced early childhood education pays long-term dividends in better health

2011-01-15
January 14, 2011 -- Intensive early education programs for low-income children have been shown to yield numerous educational benefits, but few studies have looked more broadly at their impact on health and health behaviors. A new study conducted by researchers at Columbia University's Mailman School of Public Health examines this issue, using data from a the well-known Carolina Abecedarian Project (ABC), a randomized control study that enrolled 111 infants in the 1970s and continued to follow them through age 21. Researchers found that individuals who had received the ...

Improved measurements of sun to advance understanding of climate change

Improved measurements of sun to advance understanding of climate change
2011-01-15
WASHINGTON—Scientists have taken a major step toward accurately determining the amount of energy that the sun provides to Earth, and how variations in that energy may contribute to climate change. In a new study of laboratory and satellite data, researchers report a lower value of that energy, known as total solar irradiance, than previously measured and demonstrate that the satellite instrument that made the measurement—which has a new optical design and was calibrated in a new way—has significantly improved the accuracy and consistency of such measurements. The new ...

Researchers discover way to halt lung inflammation in animal models

2011-01-15
AURORA, Colo. (Jan. 14, 2011) - Acute inflammation of the lung is a poorly recognized human disease that develops in surprising and unexpected ways. The acute lung injury (ALI) or adult respiratory distress syndrome (ARDS) is a vital new concern for soldiers, but it can develop in anyone during a systemic infection, after severe trauma, as a result of bone fracture, following severe burns and in many other ways as well-- the initial cause may have nothing apparent to do with the lung itself. However, an answer to halting lung inflammation may have been discovered, thanks ...
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