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Thinking outside the doctor’s office: Poll looks at older adults’ use of urgent care, retail clinics and more

2024-04-10
When today’s older adults were growing up, urgent care centers and clinics inside retail stores didn’t exist. But most of them have now embraced these non-traditional sites for getting medical care, a new national poll finds.   In the past two years, 60% of people age 50 to 80 have visited an urgent care clinic, or a clinic based in a retail store, workplace or vehicle, according to new findings from the University of Michigan National Poll on Healthy Aging.   Urgent care clinics were the most ...

New mechanism discovered for the life-threatening arrhythmias in Andersen-Tawil syndrome

New mechanism discovered for the life-threatening arrhythmias in Andersen-Tawil syndrome
2024-04-10
A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has made a breakthrough discovery in the understanding of cardiac arrhythmias by unraveling the complexities of Andersen-Tawil syndrome (ATS), an extremely rare inherited cardiac disorder. Led by Dr. José Jalife, head of the CNIC Cardiac Arrhythmia Group, the study demonstrates that a specific genetic mutation (C122Y) in the Kir2.1 potassium channel alters the function not only of Kir2.1 but also of the main cardiac sodium channel NaV1.5, thus establishing a direct link with the life-threatening arrhythmias associated with ATS1. The study, published in the journal Circulation Research, reveals that ...

Study suggests racial discrimination during midlife associated with Alzheimer’s disease pathology later in life

Study suggests racial discrimination during midlife associated with Alzheimer’s disease pathology later in life
2024-04-10
WINSTON-SALEM, N.C. – April 10, 2024 – Racial discrimination experienced during midlife is associated with Alzheimer’s disease pathology, according to a new study from researchers at Wake Forest University School of Medicine and the University of Georgia. The findings appear online today in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. “We know that Black Americans are at an elevated risk of Alzheimer’s disease and other dementias compared to non-Hispanic ...

The future of xenotransplantation is nearly here

2024-04-10
Embargoed until 10:30 a.m. Wednesday, 10 April, 2024 Central European Summer Time (GMT +2) 10 April, 2024, Prague, Czech Republic—Speaking today at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) in Prague, Muhammad Mohiuddin, MBBS, said xenotransplantation, hailed as the future of organ transplantation, is poised to become a clinical reality within the next several years.   In January 2022, the University of Maryland School of Medicine (UMSOM) became the first institution in the world to implant a genetically modified pig heart ...

Treating gum disease after heart rhythm ablation reduced risk of AFib recurrence

2024-04-10
Research Highlights: Treating gum disease within three months after a heart procedure to correct an irregular heart rhythm, known as atrial fibrillation (AFib), may lower the chances of it reoccurring. Inflamed gums may predict AFib recurrence after heart ablation, a procedure to fix the irregular heartbeat. AFib patients should be examined for gum disease and encouraged to seek dental treatment, researchers said. Embargoed until 4 a.m. CT/5 a.m. ET Wednesday, April 10, 2024 DALLAS, April 10, 2024 — Treating gum disease in the 3-months after a procedure to correct an irregular heartbeat known as atrial fibrillation ...

AI makes retinal imaging 100 times faster, compared to manual method

AI makes retinal imaging 100 times faster, compared to manual method
2024-04-10
Researchers at the National Institutes of Health applied artificial intelligence (AI) to a technique that produces high-resolution images of cells in the eye. They report that with AI, imaging is 100 times faster and improves image contrast 3.5-fold. The advance, they say, will provide researchers with a better tool to evaluate age-related macular degeneration (AMD) and other retinal diseases. “Artificial intelligence helps overcome a key limitation of imaging cells in the retina, which is time,” said Johnny Tam, Ph.D., who leads the Clinical and Translational Imaging Section at NIH's National Eye Institute. Tam ...

Impact of aldehydes on DNA damage and aging

Impact of aldehydes on DNA damage and aging
2024-04-10
A team of researchers at Nagoya University in Japan has discovered that aldehydes are metabolic byproducts associated with premature aging. Published in Nature Cell Biology, their findings reveal insights into premature aging diseases and potential strategies to combat aging in healthy individuals such as controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.  A person's health can be harmed by aldehydes. However, the group’s findings suggest these detrimental effects also include aging. The team who made this discovery included Yasuyoshi Oka, Yuka Nakazawa, Mayuko Shimada, and Tomoo Ogi of Nagoya University.  “DNA ...

New method of measuring qubits promises ease of scalability in a microscopic package

New method of measuring qubits promises ease of scalability in a microscopic package
2024-04-10
Chasing ever-higher qubit counts in near-term quantum computers constantly demands new feats of engineering. Among the troublesome hurdles of this scaling-up race is refining how qubits are measured. Devices called parametric amplifiers are traditionally used to do these measurements. But as the name suggests, the device amplifies weak signals picked up from the qubits to conduct the readout, which causes unwanted noise and can lead to decoherence of the qubits if not protected by additional large components. More importantly, the bulky size of the amplification chain becomes technically challenging to work around as qubit counts increase ...

Study shedding new light on Earth’s global carbon cycle could help assess liveability of other planets

2024-04-10
Research has uncovered important new insights into the evolution of oxygen, carbon, and other vital elements over the entire history of Earth – and it could help assess which other planets can develop life, ranging from plants to animals and humans. The study, published today in Nature Geoscience and led by a researcher at the University of Bristol, reveals for the first time how the build up of carbon-rich rocks has accelerated oxygen production and its release into the atmosphere. Until now the exact nature of how the atmosphere became oxygen-rich has long eluded scientists and generated conflicting explanations. As carbon dioxide is steadily ...

Connecting lab-grown brain cells provides insight into how our own brains work

Connecting lab-grown brain cells provides insight into how our own brains work
2024-04-10
Tokyo, Japan – The idea of growing a functioning human brain-like tissues in a dish has always sounded pretty far-fetched, even to researchers in the field. Towards the future goal, a Japanese and French research team has developed a technique for connecting lab-grown brain-mimicking tissue in a way that resembles circuits in our brain. It is challenging to study exact mechanisms of the brain development and functions. Animal studies are limited by differences between species in brain structure and function, and brain cells grown in the lab tend to lack the characteristic ...

Breakthrough for next-generation digital displays

Breakthrough for next-generation digital displays
2024-04-10
Researchers at Linköping University, Sweden, have developed a digital display screen where the LEDs themselves react to touch, light, fingerprints and the user’s pulse, among other things. Their results, published in Nature Electronics, could be the start of a whole new generation of displays for phones, computers and tablets.  “We’ve now shown that our design principle works. Our results show that there is great potential for a new generation of digital displays where new advanced ...

Wistar scientists identify pro-aging ‘sugar signature’ in the blood of people living with HIV

Wistar scientists identify pro-aging ‘sugar signature’ in the blood of people living with HIV
2024-04-10
PHILADELPHIA — (April 10, 2024) — The Wistar Institute’s associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH). The findings, taken from a large data study comprising more than 1200 participants, are detailed in the new paper, “Immunoglobulin G N-glycan Markers of Accelerated Biological Aging During Chronic HIV Infection,” published in the journal Nature Communications. Despite advances ...

CAMH develops first ever clinically validated natural supplement to prevent postpartum blues

CAMH develops first ever clinically validated natural supplement to prevent postpartum blues
2024-04-10
A new study published in the Lancet discovery science  journal eClinicalMedicine has confirmed that a novel natural supplement—invented, researched, developed and commercialized at the Centre for Addiction and Mental Health (CAMH)—prevents postpartum blues, and reduces symptoms of postpartum depression over the following six months after giving birth. Up to 8 out of ten new mothers experience postpartum, or ‘baby,’ blues, characterized by mood swings, crying spells, anxiety and difficulty sleeping. The condition usually begins within the first few days after delivery and may last for up to two weeks. Postpartum ...

Breakthroughs in durable mechanical circulatory support (MCS) devices add years to lives and life to years for heart failure patients

2024-04-10
Embargoed until 10:00 a.m. Wednesday, 10 April, 2024 Central European Summer Time (GMT +2) 10 April, 2024, Prague, Czech Republic—The same technology that enables a bullet train to travel at speeds up to 200 mph without touching its rails now keeps a failing heart pumping—and in the near future, it will do so via a wireless power connection. Mandeep R. Mehra, MD, FRCP described the cutting-edge heart pump and other advances in mechanical circulatory support (MCS) today at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) in ...

AI will provide heart transplant surgeons with new decision-making data

2024-04-10
Embargoed until 10:00 a.m., Wednesday, 10 April, 2024 Central European Summer Time (GMT +2) 10 April 2024, Prague, Czech Republic—Artificial intelligence will significantly impact the heart transplantation process by helping physicians better assess the complex factors impacting patient outcomes, according to researchers at today’s Annual Meeting and Scientific Sessions of the International Society of Heart and Lung Transplantation (ISHLT) in Prague.   “Until now, we’ve assessed the likelihood of transplant success based on individual risk factors,” said Eileen Hsich, medical director of the Heart Transplant Program at the Cleveland ...

Novel UV broadband spectrometer revolutionizes air pollutant analysis

Novel UV broadband spectrometer revolutionizes air pollutant analysis
2024-04-10
Sunlight has a major influence on chemical processes. Its high-energy UV radiation in particular is strongly absorbed by all materials and triggers photochemical reactions of the substances present in the air. A well-known example is the formation of ground-level ozone when UV light hits nitrogen oxides. A research team led by Birgitta Schultze-Bernhardt from the Institute of Experimental Physics at Graz University of Technology (TU Graz) is now utilising this high reaction potential for a new method of environmental monitoring. ...

Kyiv’s Heart Institute keeps transplanting hearts despite war

2024-04-10
Embargoed until 8:30 a.m. Wednesday, 10 April, 2024, Central European Summer Time  10 April, 2024, Prague, Czech Republic—Amid the persistent threat of missiles from the air and an array of hazardous terrestrial obstacles, the Heart Institute of the Ministry of Health in Kyiv has continued to provide heart transplants to Ukraine’s citizens, performing 40 of the life-saving procedures since Russia’s full-scale invasion of the country in 2022. The Heart Institute’s Director Borys Todurov, MD, PhD, reported on his team’s extraordinary efforts today at the Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation ...

Can artificial intelligence techniques help clinicians assess and treat patients with bone fractures?

2024-04-10
Investigators have applied artificial intelligence techniques to gait analyses and medical records data to provide insights about individuals with leg fractures and aspects of their recovery. The study, which is published in the Journal of Orthopaedic Research, uncovered a significant association between the rates of hospital readmission after fracture surgery and the presence of underlying medical conditions. Correlations were also found between underlying medical conditions and orthopedic complications, although these links were not significant. It was also ...

Can probiotics plus vitamin D supplements benefit people with schizophrenia?

2024-04-10
Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia. New research published in Neuropsychopharmacology Reports now indicates that taking probiotics plus vitamin D supplements may improve cognitive function in individuals with the disease. For the study, 70 adults with schizophrenia were randomized to take a placebo or probiotic supplements plus 400 IU vitamin D daily for 12 weeks. Severity of the disease and cognitive function were evaluated by tests called the Positive and Negative Syndrome Scale (PANSS) and the 30-point Montreal Cognitive Assessment (MoCA), respectively. A total of 69 patients completed the study. The MoCA ...

Could novel immune cell therapy combat hepatitis B infections?

2024-04-10
Chronic infection with the hepatitis B virus (HBV) causes progressive liver problems, and eradication of the virus remains a formidable challenge. New research in FEBS Letters indicates that treatment that boosts the effects of immune cells called stem cell memory T cells (TSCMs) may be a promising strategy for combating HBV. In the study, investigators identified TSCMs in patients with chronic HBV infection and analyzed their effects in a mouse model of HBV. After introducing TSCMs from patients ...

Women aged older than 65 years may be able to safely continue taking hormone therapy

2024-04-10
CLEVELAND, Ohio (April 10, 2024)—After the Women’s Health Initiative (WHI) in 2002, many women have resisted taking hormone therapy (HT), especially after age 65 years, because of fears of increased risks for various cancers and heart disease. A new study shows that those fears may be unfounded, depending on the type, route, and dose of HT. Results of the study are published online today in Menopause, the journal of The Menopause Society. Despite the conflicting results of a follow-up WHI study in 2004 and dozens of other studies since that time, a percentage of healthcare professionals and their middle-aged female patients continue to believe that ...

Four-part nutrition intervention program reduced adolescent malnutrition in Tanzania

2024-04-10
Adolescence is an important period of life for healthy growth. Malnutrition during this seminal period may have long-term adverse effects on health and development. In sub-Saharan Africa, there is a lack of nutrition programming for adolescents. Adolescent malnutrition represents an urgent issue in sub-Saharan Africa, which has a long history of undernutrition and a rising issue of overweight and obesity.  Findings from a new study suggest that a four-component school-based nutritional intervention package improved ...

High-brightness green InP-based QLEDs enabled by in-situ passivating core surface with zinc myristate

High-brightness green InP-based QLEDs enabled by in-situ passivating core surface with zinc myristate
2024-04-10
Compared with Cd-based QDs, InP-based QDs have lower photoluminescence quantum yields (PL QYs) and broader full-width at half-maximum (FWHM). In particular, bare InP core has extremely low PL QY (<1%) due to the ease of oxidation of their highly reactive surface even in insert reaction chambers. It has been reported that the defects from oxidative species are probably the reasons for the non-radiative recombination and poor PL QY of these materials. Over the last decade, extensive studies have been conducted to improve the optoelectronic properties of InP-based QDs for display and lighting applications, ...

Does the time of day you move your body make a difference to your health?

2024-04-10
Undertaking the majority of daily physical activity in the evening is linked to the greatest health benefits for people living with obesity, according to researchers from the University of Sydney, Australia who followed the trajectory of 30,000 people over almost 8 years. Using wearable device data to categorise participant’s physical activity by morning, afternoon or evening, the researchers uncovered that those who did the majority of their aerobic moderate to vigorous physical activity– the kind that raises our heartrate and gets us out of breath– between 6pm and midnight had the lowest risk of premature ...

How does China’s Agricultural Green Development promote the achievement of the Sustainable Development Goals?

How does China’s Agricultural Green Development promote the achievement of the Sustainable Development Goals?
2024-04-10
Against the backdrop of global challenges such as climate change, diminishing natural resources, and the need to feed a growing population, the imperative for fostering worldwide agricultural sustainability has reached unprecedented levels. China’s Agricultural Green Development (AGD) serves as an important model for global sustainable agricultural development. What advantages does this model offer in terms of concept and implementation path compared to other international sustainable agriculture initiatives? What ...
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