Prudential UK has entered into two bulk annuity buy-in contracts with the Trustees of the GlaxoSmithKline ("GSK") Pension Scheme and the GSK Pension Fund for a tranche of pensioner members within their defined benefit pension schemes. The transactions cover around 15 per cent of GSK's UK defined benefit pensioner liabilities and have an aggregate value of approximately GBP900 million. Under the terms of the agreement, GSK has purchased bulk annuity policies from Prudential which will take on responsibility for a portion of the pensioner benefits payable by the Trustees ...

Avalon Waterways continues to be the UK's fastest growing river cruise company with the youngest fleet on Europe's waterways as ships average 2 years in age. This year saw the launch of two new ships, the MS Avalon Felicity and MS Avalon Luminary, with another due to come into service in 2011, MS Avalon Panorama. Avalon Felicity and Luminary feature the same contemporary and innovative design as their sister ships, offering the most spacious and well-appointed staterooms in European river cruising. Sized at 172 square feet, the staterooms are the largest on Europe's ...

Some of us are familiar with the electronic cigarettes, some of us have tried earlier versions to help in the battle to quit smoking and have had some success. Well the newer, or version 2.0, units are on the shelves at stores and on the Internet now. This newer 2-piece model has the atomizer built into each refill cartridge. This technology has greatly improved the experience. These newer version 2.0 e cigs produce a much greater volume of vapor which gives the user the same exact look, taste and feel of lighting up the regular way. In fact, a recent independent study ...

AURORA, Colo. (Nov. 22, 2010) – Doctors at the University of Colorado School of Medicine were concerned recently when they found a nodule in the thyroid of a 64-year-old Colorado man. They extracted cells from the nodule, hoping to determine whether the man had cancer. But the biopsy results were inconclusive. Even a few months ago, such uncertainty would have likely led to surgery to remove all or part of the thyroid. At least this patient would have faced a tense waiting period to see if, over time, he developed clear signs of cancer. This time, however, the CU doctors ...

WASHINGTON, D.C., November 23, 2010 -- For centuries, intellectuals have met at the ring-stained surfaces of coffee shops to pore over the most pressing problems of the day -- but has anyone ever pondered the coffee rings they left behind? What causes the formation of stain patterns left behind by coffee droplets on a surface? You might think coffee ring formation, first described quantitatively by Deegan et al in a heavily cited article, is the most widely and ritualistically performed experiment in the world, given the prevalence of caffeine in cultures. But most of ...

WASHINGTON, D.C., November 23, 2010 -- Wind farms around the world are large and getting larger. Arranging thousands of wind turbines across many miles of land requires new tools that can balance cost and efficiency to provide the most energy for the buck. Charles Meneveau, who studies fluid dynamics at Johns Hopkins University, and his collaborator Johan Meyers from Leuven University in Belgium, have developed a model to calculate the optimal spacing of turbines for the very large wind farms of the future. They will present their work today at the American Physical ...

WASHINGTON, D.C., November 23, 2010 -- To the causal aquarium visitor, the jellyfish doesn't seem to be a particularly powerful swimmer; compared to a fish, it glides slowly and peacefully. But for Janna Nawroth, a graduate student at the California Institute of Technology in Pasadena, the undulations of this simple invertebrate hold secrets that may make possible a new generation of tiny pumps for medical applications and soft robotics -- work she describes today at the American Physical Society Division of Fluid Dynamics (DFD) meeting in Long Beach, CA "Most pumps ...

WASHINGTON, D.C., November 23, 2010 -- Magnetic fluid hyperthermia (MFH) is a promising new cancer treatment that essentially "fries" cells inside tumors. The procedure has been used successfully in prostate, liver, and breast tumors. Magnetic nanoparticles (each billionths of a meter in size) are injected into the body intravenously and diffuse selectively into cancerous tissues. Add a high-frequency magnetic field, and the particles heat up, raising the temperature of the tumor cells. "The entire tumor volume is heated above a threshold treatment temperature -- typically ...

WASHINGTON, D.C., November 23, 2010 -- New research from the University of South Florida suggests that one of the evolutionary secrets of the shark's success hides in one of its tiniest traits -- flexible scales on the bodies of these peerless predators that make them better hunters by allowing them to change directions while moving at full speed. The key to this ability lies in the fact that the scales control water flow separation across the creatures' bodies, says Amy Lang of the University of Alabama who will present work she performed with her colleagues at the University ...

Pity the poor female fruit fly. Being a looker is simply not enough, it seems. If you're to get a date, much less a proposal, you must also smell and act like a girl. Otherwise, you might just have a fight on your hands. Read more in next week's issue of the online, open access journal PLoS Biology. As with most animals, Drosophila face the problem of distinguishing between a potential mate and a potential competitor. If, when meeting a second fruit fly, a male fly thinks "female," he'll begin courting her. But if he senses another male, he'll fight. What triggers these ...

### El Consejo Civil Mexicano para la Silvicultura Sostenible, A.C. (the Mexican Civil Council for Sustainable Forestry, known as CCMSS) is a non-profit, non-governmental organization that encourages and promotes conservation of forest ecosystems that are managed by the forest communities themselves. Known as Manejo Forestal Comunitario, or MFC, this system is supported by CCMSS members, who work in collaboration with communities and ejidos to put in place sustainable practices in forest management and improve the development, conservation, industrialization and commercialization ...

Performing a combination of aerobic exercise and resistance training was associated with improved glycemic levels among patients with type 2 diabetes, compared to patients who did not exercise, according to a study in the November 24 issue of JAMA. The level of improvement was not seen among patients who performed either aerobic exercise or resistance training alone. Although it is generally accepted that regular exercise provides substantial health benefits for individuals with type 2 diabetes, the exact exercise type (aerobic vs. resistance vs. both) has been unclear. ...

A comparison of two strategies to determine the stage of suspected non-small cell lung cancer (NSCLC) finds that the less invasive method is more effective at identifying a type of lung cancer that has spread, and may result in a reduction of unnecessary surgical procedures and associated adverse effects for certain patients, according to a study in the November 24 issue of JAMA. Lung cancer is the most commonly diagnosed cancer worldwide (1.35 million/year) and also the most frequent cause of cancer death (1.2 million/year). Determining the stage of cancer is an important ...

Annual screening by fecal immunochemical testing—a test that detects blood in the stool, has high sensitivity and specificity, and might improve participation rates through increased patient acceptability—reduces the risk of colorectal cancer and colorectal cancer related deaths, and reduces healthcare costs in comparison to all other screening strategies and to no screening. These are the conclusions of a complete economic evaluation performed by Braden Manns and colleagues from the University of Calgary, Alberta, Canada, and published in this week's PLoS Medicine. Clinical ...

China had an estimated 1.3 million new cases of tuberculosis (TB) in 2008, of which 112,000 were multi-drug resistant (MDR-TB). Over the period 2001, TB was the second largest cause of death among China's 39 notifiable communicable diseases. In a Policy Forum, published in this week's PLoS Medicine, Zhong-wei Jia (Peking University) and colleagues from Beijing, China, report on how a combination of increased domestic funding, supplemented by foreign loans and donations, led to a dramatic increase in TB case finding. The authors also highlight the way in which changes in ...

Every magnetic material is divided into such magnetic domains. Scientists call them "Weiss domains" after physicist Pierre-Ernest Weiss, who predicted their existence theoretically more than a hundred years ago. In 1907, he recognized that the magnetic moments of atoms within a bounded domain are equally aligned. All pursuit of this theory has so far been limited to two-dimensional images and material surfaces. Accordingly, researchers have only ever been able to see a domain in cross section. Together with colleagues from the German Federal Institute for Materials Research ...

BIRMINGHAM, Ala. – So, why are we fat? And getting fatter? Most people would say it's simple: We eat too much and exercise too little. But University of Alabama at Birmingham obesity researcher David B. Allison, Ph.D., says that answer, while valid, may be a little too simple. Allison and colleagues think the more relevant question is this: Why do we eat too much and expend too little energy? And like good detectives, they've set out to identify a suspect, or suspects, that may be contributing to the obesity epidemic. The game, as they say, is afoot. Allison, a professor ...

Giant pterosaurs – ancient reptiles that flew over the heads of dinosaurs – were at their best in gentle tropical breezes, soaring over hillsides and coastlines or floating over land and sea on thermally driven air currents, according to new research from the University of Bristol. Pterosaurs (also referred to as pterodactyls) were too slow and flexible to use the stormy winds and waves of the southern ocean like the albatrosses of today, the research by Colin Palmer, an engineer turned paleontology PhD student in Bristol's School of Earth Sciences, found. Their slow ...

The study, by Dr Lavinia Mitton and Mr Peter Aspinall of the University of Kent, finds that 'Black Africans' in the UK are a diverse group with a wide range of experience and needs depending on country of birth, religion and native language. Understanding these distinctions between different Black Africans is the first step to providing better support, improving their quality of life and helping integration into society. There are now 737,000 'Black Africans' in England and Wales (according to an estimate by the Office for National Statistics for 2007) and they are one ...

BOSTON, Mass. (Nov. 23, 2010) — Pity the female fruit fly. Being a looker is simply not enough. To get a date, much less a proposal, you have to act like a girl, even smell like one. Otherwise, you might just have a fight on your hands. Like most animals, fruit flies must distinguish between a potential mate and a potential competitor. When a male fruit fly suspects he's encountered a female, he'll court; when he senses the other is a male, he'll fight. What triggers these sex-specific responses? According to new research by scientists at Harvard Medical School, the ...

Large predators are much more vulnerable than smaller species to environmental changes, such as over-hunting and habitat change, because they have to work so hard to find their next meal, according to a new study. Scientists matched studies of predator populations to the abundance of their prey and found that the largest species, such as lions, tigers or polar bears, had much greater declines in population due to diminishing food supplies than smaller species, such as weasels or badgers. The review of studies of eleven species of carnivores by researchers from Durham ...

Chicago, November 23, 2010 – Results of the world's first efficacy trial of an HIV-prevention approach called oral pre-exposure prophylaxis, or PrEP, were released online in the New England Journal of Medicine today. Data from this trial, called iPrEx, indicated an estimated 43.8% reduction of new HIV infections among men who took an antiretroviral tablet daily to prevent HIV, compared to those who took a placebo pill. "This discovery alters the HIV prevention landscape forever. While this level of efficacy is relatively strong, PrEP is not quite ready for prime time ...

PITTSBURGH, Nov. 23, 2010 – In a significant advance for HIV prevention research, a clinical trial confirms that the same drugs used for treating HIV can also help prevent HIV infection in the first place. The study, known as iPrEx, is important because it gives credence to an HIV prevention approach called oral pre-exposure prophylaxis (PrEP), which involves the use of antiretrovirals (ARVs) by people who are HIV-negative and at high risk of infection. It is the first of five large-scale effectiveness trials testing oral PrEP to report results, which were published online ...

The results of the iPrEx PrEP effectiveness trial of once-daily TDF/FTC (brand name Truvada) in gay men, transgender women and other men who have sex with men are a landmark in HIV prevention research. The results, released on November 23, showed that TDF/FTC reduced risk of HIV infection by an average of 43.8%. This was calculated by looking at rates of infections among participants who received TDF/FTC plus a standard prevention package compared to those in the placebo arm who received a look-alike pill with no active drug, along with the prevention package. All of the ...

Belfast's binge drinking culture could be behind the country's high rates of heart disease, according to a paper published on bmj.com today. The study, which compares drinking patterns of middle aged men in France and Belfast, finds that the volume of alcohol consumed over a week in both countries is almost identical. However, in Belfast alcohol tends to be drunk over one or two days rather than regularly throughout the week as in France. The research also finds that the average amount of alcohol consumed in Belfast over the weekend is around 2-3 times higher than ...