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E. coli infection linked to long-term health problems

2010-11-19
People who contract gastroenteritis from drinking water contaminated with E. coli are at an increased risk of developing high blood pressure, kidney problems and heart disease in later life, finds a study published on bmj.com today. The findings underline the importance of ensuring a safe food and water supply and the need for regular monitoring for those affected. It is estimated that E. coli O157:H7 infections cause up to 120,000 gastro-enteric illnesses annually in the US alone, resulting in over 2,000 hospitalisations and 60 deaths. However, the long term health ...

Researchers learn that genetics determine winter vitamin D status

2010-11-19
Vitamin D is somewhat of an unusual "vitamin," because it can be made in the body from sunlight and most foods do not contain vitamin D unless added by fortification. Synthesis of vitamin D in the body requires exposure to ultraviolet light and can be influenced by genetics, skin color, and sun exposure. Reports of greater than expected vitamin D insufficiency coupled with emerging evidence that higher circulating concentrations of this nutrient may protect against cardiovascular disease have prompted a renewed interest in teasing out how environment, genetics, and behavior ...

Why so many antibodies fail to protect against HIV infection

2010-11-19
DURHAM, NC – Researchers have been stymied for years over the fact that people infected with the AIDS virus do indeed produce antibodies in response to the pathogen – antibodies that turn out to be ineffective in blocking infection. Now, scientists at Duke University Medical Center can explain why: Some of the earliest and most abundant antibodies available to fight HIV can't actually "see" the virus until after it's already invaded a healthy cell. The scientists based their conclusion on the results of a series of crystallography and biochemical experiments that revealed ...

Economic downturn takes toll on health of Americans with heart disease, diabetes or cancer

2010-11-19
Boston, MA – A new poll from researchers at the Harvard School of Public Health (HSPH) and Knowledge Networks (KN) shows that many people with heart disease, diabetes or cancer believe the economic downturn is hurting their health and will have further negative impacts in the future. Many Americans with these illnesses face financial problems paying for medical bills in this economy. Most of these people do not believe the new national health care reform law (Patient Protection and Affordable Care Act 2010) will help them. This national poll is the first in a collaborative ...

Reduce the VAT on alcohol sold in pubs, says expert

2010-11-19
Alcoholic drinks served in pubs should be taxed at a lower level than drinks bought from shops, says an expert in this week's BMJ. This action would deliver the health benefits associated with introducing a minimum price on alcohol, increase tax revenue for the Treasury and save pubs says Dr Nick Sheron. The author is head of clinical hepatology at the University of Southampton, a member of the Alcohol Health Alliance and an advisor for the 2010 House of Commons Select Committee Report on Alcohol. Sheron says lowering VAT for alcohol sold in pubs would solve the plight ...

LSUHSC reports first successful salivary stone removal with robotics

2010-11-19
New Orleans, LA – Dr. Rohan Walvekar, Assistant Professor of Otolaryngology Head and Neck Surgery, Director of Clinical Research and the Salivary Endoscopy Service at LSU Health Sciences Center New Orleans, has reported the first use of a surgical robot guided by a miniature salivary endoscope to remove a 20mm salivary stone and repair the salivary duct of a 31-year-old patient. Giant stones have traditionally required complete removal of the salivary gland. Building upon their success with the combination of salivary endoscopic guidance with surgery, Dr. Walvekar and his ...

Teenage girls face greater violence threat from poverty

2010-11-19
Living in a deprived area increases the risk of violence more sharply for girls than boys, according to a Cardiff University study of former industrial areas. The new results suggest violence prevention strategies need to focus more on local inequalities, especially to protect vulnerable adolescent girls. The survey was conducted by the Violence and Society Research Group at Cardiff University. The team studied nearly 700 young people, aged 11 to 17, who attended casualty departments in South Wales with injuries from violence. The researchers matched the patients against ...

Gene therapy for metastatic melanoma in mice produces complete remission

Gene therapy for metastatic melanoma in mice produces complete remission
2010-11-19
INDIANAPOLIS – A potent anti-tumor gene introduced into mice with metastatic melanoma has resulted in permanent immune reconfiguration and produced a complete remission of their cancer, according to an article to be published in the December 2010 issue of the Journal of Clinical Investigation. The online version is now available. Indiana University School of Medicine researchers used a modified lentivirus to introduce a potent anti-melanoma T cell receptor gene into the hematopoietic stem cells of mice. Hematopoietic stem cells are the bone marrow cells that produce all ...

Well-known molecule may be behind alcohol's benefits to heart health

2010-11-19
Many studies support the assertion that moderate drinking is beneficial when it comes to cardiovascular health, and for the first time scientists have discovered that a well-known molecule, called Notch, may be behind alcohol's protective effects. Down the road, this finding could help scientists create a new treatment for heart disease that mimics the beneficial influence of modest alcohol consumption. "Any understanding of a socially acceptable, modifiable activity that many people engage in, like drinking, is useful as we continue to search for new ways to improve ...

Pushing black-hole mergers to the extreme: RIT scientists achieve 100:1 mass ratio

Pushing black-hole mergers to the extreme: RIT scientists achieve 100:1 mass ratio
2010-11-19
Scientists have simulated, for the first time, the merger of two black holes of vastly different sizes, with one mass 100 times larger than the other. This extreme mass ratio of 100:1 breaks a barrier in the fields of numerical relativity and gravitational wave astronomy. Until now, the problem of simulating the merger of binary black holes with extreme size differences had remained an unexplored region of black-hole physics. "Nature doesn't collide black holes of equal masses," says Carlos Lousto, associate professor of mathematical sciences at Rochester Institute ...

Cameroon timber tax study shows challenges of distributing REDD payments to local communities

2010-11-19
YAOUNDÉ, Cameroon (19 November 2010) – A new study finds a lack of transparency and corruption are reducing the impact of an initiative in Cameroon that channels a portion of national timber levies to rural forest communities. The study highlights the challenges of using a climate change pact to do something similar in forested regions around the world. In an article published in the peer-reviewed journal International Forestry Review, scientists at the Center for International Forestry Research (CIFOR) examined how revenues from a tax paid by logging companies in Cameroon, ...

Researchers insert identification codes into mouse embryos

2010-11-19
Researchers from the Department of Cell Biology, Physiology and Immunology at Universitat Autònoma de Barcelona (UAB), in collaboration with researchers from the Institute of Microelectronics of Barcelona (IMB-CNM) of the Spanish National Research Council (CSIC), have developed an identification system for oocytes and embryos in which each can be individually tagged using silicon barcodes. Researchers are now working to perfect the system and soon will test it with human oocytes and embryos. The research, published online in Human Reproduction, represents a first step ...

Laboratory studies show promise for new multiple sclerosis treatment

2010-11-19
Successfully treating and reversing the effects of multiple sclerosis, or MS, may one day be possible using a drug originally developed to treat chronic pain, according to Distinguished Professor Linda Watkins of the University of Colorado at Boulder. Watkins and her colleagues in CU-Boulder's department of psychology and neuroscience discovered that a single injection of a compound called ATL313 -- an anti-inflammatory drug being developed to treat chronic pain -- stopped the progression of MS-caused paralysis in rats for weeks at a time. Lisa Loram, a senior research ...

Bacteria use 'toxic darts' to disable each other, according to UCSB scientists

Bacteria use toxic darts to disable each other, according to UCSB scientists
2010-11-19
(Santa Barbara, Calif.) –– In nature, it's a dog-eat-dog world, even in the realm of bacteria. Competing bacteria use "toxic darts" to disable each other, according to a new study by UC Santa Barbara biologists. Their research is published in the journal Nature. "The discovery of toxic darts could eventually lead to new ways to control disease-causing pathogens," said Stephanie K. Aoki, first author and postdoctoral fellow in UCSB's Department of Molecular, Cellular, and Developmental Biology (MCDB). "This is important because resistance to antibiotics is on the rise." Second ...

Wellness programs provide high returns, research reveals

2010-11-19
Employee wellness programs have often been viewed as a nice extra, not a strategic imperative. But the data demonstrate otherwise, according to a team of researchers led by Leonard L. Berry of Texas A&M University, Ann M. Mirabito of Baylor University and William B. Baun of the University of Texas MD Anderson Cancer Center. Their research shows that the return on investment on comprehensive, well-run employee wellness programs is impressive — sometimes as high as six to one. The findings are compiled in a comprehensive piece in the December issue of Harvard Business ...

Spacecraft flew through 'snowstorm' on encounter with comet Hartley 2

Spacecraft flew through snowstorm on encounter with comet Hartley 2
2010-11-19
COLLEGE PARK, Md. -- On its recent trip by comet Hartley 2, the Deep Impact spacecraft took the first pictures of, and flew through, a storm of fluffy particles of water ice being spewed out by carbon dioxide jets coming from the rough ends of the comet. The resulting images and data shed new light on the nature and composition of comets, according to the University of Maryland-led EPOXI science team, which today announced its latest findings and released the first images of this comet created snowstorm. See images at: http://epoxi.umd.edu/index.shtml "When we visited ...

Latest American Chemical Society podcast: New water filter kills disease-causing bacteria

2010-11-19
WASHINGTON, Nov. 18, 2010 — The latest episode in the American Chemical Society's (ACS) award-winning podcast series, "Global Challenges/Chemistry Solutions," focuses on development and successful initial tests of an inexpensive new filtering technology that kills up to 98 percent of disease-causing bacteria in water in just seconds without clogging. The technology could aid many of the almost one billion people lacking access to clean, safe drinking water. A report on the work appears in the American Chemical Society's monthly journal Nano Letters. Most water purifiers ...

Researchers identify PTSD measures for use in traumatic brain injury research

2010-11-19
(Boston) - Five U.S. federal agencies recently cosponsored a set of expert work groups to formulate common data elements for research related to psychological adjustment and traumatic brain injury (TBI). Danny G. Kaloupek, PhD, associate professor of psychiatry and behavioral neuroscience at Boston University School of Medicine, chaired the work group on posttraumatic stress disorder (PTSD). Dr. Kaloupek's work at the National Center for PTSD at VA Boston Healthcare helped to guide identification of key PTSD-related characteristics and evidence-based measures that might ...

Taking a break from osteoporosis drugs can protect bones

2010-11-19
MAYWOOD, Ill. -- Taking time off from certain osteoporosis drugs may be beneficial to bone health, according to a study conducted at Loyola University Health System. Researchers found that bone density remained stable for three years in patients who took a drug holiday from bisphosphonates, a popular class of osteoporosis drugs that can cause fractures in the thigh bones and tissue decay in the jaw bone. "These drugs are potentially harmful when taken for long durations, yet little has been known until now about the length of time osteoporosis patients should go without ...

Al Jazeera helps shape political identity of Arabs, study finds

2010-11-19
COLUMBUS, Ohio – Residents of the Middle East who are heavy viewers of Arab television news networks like Al Jazeera are more likely to view their primary identity as that of Muslims, rather than as citizens of their own country, a new study suggests. Because networks like Al Jazeera are transnational – focusing on events of interest across the region rather than those in any one country – they may encourage viewers to see themselves in broader terms than simply residents of a particular nation, the researchers said. "The goal of these relatively new networks is not ...

Culturally sensitive treatment model helps bring depressed Chinese immigrants into treatment

2010-11-19
A treatment model designed to accommodate the beliefs and concerns of Chinese immigrants appears to significantly improve the recognition and treatment of major depression in this typically underserved group. In a report in the December American Journal of Public Health, a Massachusetts General Hospital (MGH) research team describes how their model for screening and assessing patients for depression in a primary care setting increased the percentage of depressed patients entering treatment nearly sevenfold. "Ours is the first study to incorporate a culturally sensitive ...

What factors contribute to the success or failure of software firms?

2010-11-19
PITTSBURGH—Throughout the 1990s and 2000s, news about 20-somethings becoming billionaires from the sale of their software companies flooded the media, giving the impression that a good idea was all it took to succeed in the software industry. Jennifer Shang, an associate professor of business management in the Joseph M. Katz Graduate School of Business, along with colleagues Shanling Li of McGill University and Sandra Slaughter of the Georgia Institute of Technology, investigated what caused software companies to succeed or fail. Their research study, titled "Why Do Software ...

Redrawing our borders

2010-11-19
What are borders these days? When travel was local, borders and communities were easy to define, but now our connectivity is more complex. It's time to think of borders differently, according to Northwestern University researchers. To reflect today's reality, they have taken a look at human mobility and redrawn the borders within the United States, showing areas of the country that are most connected. Some of the borders in this new map are familiar, but many are not. The research team, led by professor Dirk Brockmann, used the wealth of data generated by Wheres's George? ...

Assessment tool predicts blood clot risk after plastic surgery

2010-11-19
ANN ARBOR, Mich.—Patients undergoing plastic or reconstructive surgery should receive a risk assessment before their procedure to predict whether they'll develop potentially fatal blood clots in the legs or lungs, according to research at the University of Michigan Medical School. Researchers also found that 1 in 9 patients at highest risk based on that assessment will develop clots if not given clot-preventing medications after surgery. Published in the November 2010 Journal of the American College of Surgeons, the study evaluated the Caprini Risk Assessment Model, a ...

UGA researchers identify key enzyme that regulates the early growth of breast cancer cells

2010-11-19
Athens, Ga. ¬¬-- New University of Georgia research, published this week in the early online edition of the journal Proceedings of the National Academy of Sciences, has found that blocking the action of an enzyme called GnT-V significantly delays the onset and spread of tumors in mice with cancer very similar to many cases of human breast cancer. When the GnT-V enzyme activity in the cells was increased in mammary gland cells, they increased proliferation and began to take on many characteristics of cancer cells. Using a mouse model of human breast cancer, tumors appeared ...
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