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Research finds practicing retrieval is best tool for learning

Research finds practicing retrieval is best tool for learning
2011-01-26
WEST LAFAYETTE, Ind. - The time students invest in rereading or reviewing their notes would be better spent practicing retrieval to ensure better learning, according to new research from Purdue University. "We continue to show that practicing retrieval, or testing yourself, is a powerful, robust tool for learning," said Jeffrey D. Karpicke (pronounced CAR-picky), an assistant professor of psychological sciences who studies learning and memory. "Our new research shows that practicing retrieval is an even more effective strategy than engaging in elaborative studying. "Educators, ...

Tufts University calls for moderate approach to teaching personalized genomic testing

2011-01-26
BOSTON (January 24, 2011) — Genetics in Medicine, the official journal of the American College of Medical Genetics, published this month a paper by Tufts University faculty calling for a moderate, strategic approach to teaching personalized genomic testing in medical school curricula. For 16 months, a multi-disciplinary group of Tufts University faculty examined ways to improve education regarding personalized genomic testing at Tufts University School of Medicine (TUSM). The genesis of the debate centered on whether medical students should use their own genome for ...

Genome of blue stain fungus evolved to bypass tree defense in mountain pine beetle epidemic: UBC

2011-01-26
The genome of the fungus that helps mountain pine beetles infect and kill lodgepole pines has been decoded in a University of British Columbia study. Also known as blue stain fungus for the stain it leaves in the wood of infected trees, Grosmannia clavigera is carried to the host trees by pine beetles and weakens the trees' natural defense system, allowing pine beetles to feed and reproduce in the tree bark. A successful beetle-fungus attack ultimately causes tree death. Now, researchers from UBC and the BC Cancer Agency's Genome Sciences Centre have conducted a detailed ...

Rhythmic vibrations guide caste development in social wasps

2011-01-26
MADISON — Future queen or tireless toiler? A paper wasp's destiny may lie in the antennal drumbeats of its caretaker. While feeding their colony's larvae, a paper wasp queen and other dominant females periodically beat their antennae in a rhythmic pattern against the nest chambers, a behavior known as antennal drumming. The drumming behavior is clearly audible even to human listeners and has been observed for decades, prompting numerous hypotheses about its purpose, says Robert Jeanne, a professor emeritus of entomology at the University of Wisconsin-Madison. Many have ...

Scientists find that debris on certain Himalayan glaciers may prevent melting

Scientists find that debris on certain Himalayan glaciers may prevent melting
2011-01-26
(Santa Barbara, Calif.) –– A new scientific study shows that debris coverage –– pebbles, rocks, and debris from surrounding mountains –– may be a missing link in the understanding of the decline of glaciers. Debris is distinct from soot and dust, according to the scientists. Melting of glaciers in the Himalayan Mountains affects water supplies for hundreds of millions of people living in South and Central Asia. Experts have stated that global warming is a key element in the melting of glaciers worldwide. Bodo Bookhagen, assistant professor in the Department of Geography ...

Dating sheds new light on dawn of the dinosaurs

2011-01-26
Careful dating of new dinosaur fossils and volcanic ash around them by researchers from UC Davis and UC Berkeley casts doubt on the idea that dinosaurs appeared and opportunistically replaced other animals. Instead -- at least in one South American valley -- they seem to have existed side by side and gone through similar periods of extinction. Geologists from Argentina and the United States announced earlier this month the discovery of a new dinosaur that roamed what is now South America 230 million years ago, at the beginning of the age of the dinosaurs. The newly discovered ...

Cell death pathway linked to mitochondrial fusion

2011-01-26
New research led by UC Davis scientists provides insight into why some body organs are more susceptible to cell death than others and could eventually lead to advances in treating or preventing heart attack or stroke. In a paper published Jan. 21 in the journal Molecular Cell, the UC Davis team and their collaborators at the National Institutes of Health and Johns Hopkins University report that Bax, a factor known to promote cell death, is also involved in regulating the behavior of mitochondria, the structures that provide energy inside living cells. Mitochondria constantly ...

Wheat resistance genes failing, new approach needed to stop flies

Wheat resistance genes failing, new approach needed to stop flies
2011-01-26
WEST LAFAYETTE, Ind. - Many of the genes that allow wheat to ward off Hessian flies are no longer effective in the southeastern United States, and care should be taken to ensure that resistance genes that so far haven't been utilized in commercial wheat lines are used prudently, according to U.S. Department of Agriculture and Purdue University scientists. An analysis of wheat lines carrying resistance genes from dozens of locations throughout the Southeast showed that some give little or no resistance to the Hessian fly, a major pest of wheat that can cause millions of ...

Conversion of brain tumor cells into blood vessels thwarts treatment efforts

Conversion of brain tumor cells into blood vessels thwarts treatment efforts
2011-01-26
LA JOLLA, CA--Glioblastoma, the most common and lethal form of brain cancer and the disease that killed Massachusetts Senator Ted Kennedy, resists nearly all treatment efforts, even when attacked simultaneously on several fronts. One explanation can be found in the tumor cells' unexpected flexibility, discovered researchers at the Salk Institute for Biological Studies. When faced with a life-threatening oxygen shortage, glioblastoma cells can shift gears and morph into blood vessels to ensure the continued supply of nutrients, reports a team led by Inder Verma, Ph.D., ...

Purdue team creates 'engineered organ' model for breast cancer research

Purdue team creates engineered organ model for breast cancer research
2011-01-26
WEST LAFAYETTE, Ind. - Purdue University researchers have reproduced portions of the female breast in a tiny slide-sized model dubbed "breast on-a-chip" that will be used to test nanomedical approaches for the detection and treatment of breast cancer. The model mimics the branching mammary duct system, where most breast cancers begin, and will serve as an "engineered organ" to study the use of nanoparticles to detect and target tumor cells within the ducts. Sophie Lelièvre, associate professor of basic medical sciences in the School of Veterinary Medicine, and ...

Blue crab research may help Chesapeake Bay watermen improve soft shell harvest

2011-01-26
Baltimore, Md. (January 24, 2011) – A research effort designed to prevent the introduction of viruses to blue crabs in a research hatchery could end up helping Chesapeake Bay watermen improve their bottom line by reducing the number of soft shell crabs perishing before reaching the market. The findings, published in the journal Diseases of Aquatic Organisms, shows that the transmission of a crab-specific virus in diseased and dying crabs likely occurs after the pre-molt (or 'peeler') crabs are removed from the wild and placed in soft-shell production facilities. Crab ...

Loyola physician helps develop national guidelines for osteoporosis

2011-01-26
MAYWOOD, Ill. -- The American Association of Clinical Endocrinologists (AACE) has released new medical guidelines for the diagnosis and treatment of postmenopausal osteoporosis. Loyola physician Pauline Camacho, MD, was part of a committee that developed the guidelines to manage this major public health issue. These recommendations were developed to reduce the risk of osteoporosis-related fractures and improve the quality of life for patients. They explain new treatment options and suggest the use of the FRAX tool (a fracture risk assessment tool developed by the World ...

GRIN plasmonics

GRIN plasmonics
2011-01-26
They said it could be done and now they've done it. What's more, they did it with a GRIN. A team of researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California, Berkeley, have carried out the first experimental demonstration of GRIN – for gradient index – plasmonics, a hybrid technology that opens the door to a wide range of exotic optics, including superfast computers based on light rather than electronic signals, ultra-powerful optical microscopes able to resolve DNA molecules with visible ...

Women in Congress outperform men on some measures

2011-01-26
Congresswomen consistently outperform their male counterparts on several measures of job performance, according to a recent study by University of Chicago scholar Christopher Berry. The research comes as the 112th Congress is sworn in this month with 89 women, the first decline in female representation since 1978. The study authors argue that because women face difficult odds in reaching Congress – women account for fewer than one in six representatives – the ones who succeed are more capable on average than their male colleagues. Women in Congress deliver more federal ...

Legal restrictions compromise effectiveness of advance directives

2011-01-26
Current legal restrictions significantly compromise the clinical effectiveness of advance directives, according to a study by researchers at the University of California, San Francisco. Advance directives allow patients to designate health care decision-makers and specify health care preferences for future medical needs. However, "the legal requirements and restrictions necessary to execute a legally valid directive prohibit many individuals from effectively documenting their end-of-life wishes," said lead author Lesley S. Castillo, BA, a geriatrics research assistant ...

Neurologists predict more cases of stroke, dementia, Parkinson's disease and epilepsy

2011-01-26
MAYWOOD, Ill. -- As the population ages, neurologists will be challenged by a growing population of patients with stroke, dementia, Parkinson's disease and epilepsy. The expected increase in these and other age-related neurologic disorders is among the trends that Loyola University Health System neurologists Dr. José Biller and Dr. Michael J. Schneck describe in a January, 2011, article in the journal Frontiers in Neurology. In the past, treatment options were limited for patients with neurological disorders. "Colloquially, the neurologist would 'diagnose and adios,'" ...

Preschool kids know what they like: Salt, sugar and fat

Preschool kids know what they like: Salt, sugar and fat
2011-01-26
EUGENE, Ore. -- (Jan. 25, 2011) -- A child's taste preferences begin at home and most often involve salt, sugar and fat. And, researchers say, young kids learn quickly what brands deliver the goods. In a study of preschoolers ages 3 to 5, involving two separate experiments, researchers found that salt, sugar and fat are what kids most prefer -- and that these children already could equate their taste preferences to brand-name fast-food and soda products. In a world where salt, sugar and fat have been repeatedly linked to obesity, waiting for children to begin school ...

Biologists' favorite worm gets viruses

Biologists favorite worm gets viruses
2011-01-26
A workhorse of modern biology is sick, and scientists couldn't be happier. Researchers at Washington University School of Medicine in St. Louis, the Jacques Monod Institute in France and Cambridge University have found that the nematode C. elegans, a millimeter-long worm used extensively for decades to study many aspects of biology, gets naturally occurring viral infections. The discovery means C. elegans is likely to help scientists study the way viruses and their hosts interact. "We can easily disable any of C. elegans' genes, confront the worm with a virus and ...

Possible new approach to treating a life-threatening blood disorder

2011-01-26
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease of the blood system. The condition is caused by the presence of ultralarge multimers of the protein von Willebrand factor, which promote the formation of blood clots (thrombi) in small blood vessels throughout the body. Current treatments are protracted and associated with complications. However, a team of researchers, led by José López, at the Puget Sound Blood Center, Seattle, has generated data in mice that suggest that the drug N-acetylcysteine (NAC), which is FDA approved as a treatment for chronic ...

JCI table of contents: Jan. 25, 2011

2011-01-26
EDITOR'S PICK: Possible new approach to treating a life-threatening blood disorder Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disease of the blood system. The condition is caused by the presence of ultralarge multimers of the protein von Willebrand factor, which promote the formation of blood clots (thrombi) in small blood vessels throughout the body. Current treatments are protracted and associated with complications. However, a team of researchers, led by José López, at the Puget Sound Blood Center, Seattle, has generated data in mice that suggest ...

After stroke, admission to designated stroke center hospitals associated with reduced risk of death

2011-01-26
Patients who had an ischemic stroke and were admitted to hospitals designated as primary stroke centers had a modestly lower risk of death at 30 days, compared to patients who were admitted to non-designated hospitals, according to a study in the January 26 issue of JAMA. Stroke is the leading cause of serious long-term disability and the third leading cause of death in the United States. Responding to the need for improvements in acute stroke care, the Brain Attack Coalition (BAC) published recommendations for the establishment of primary stroke centers in 2000, and ...

Occurrence of stroke after coronary artery bypass graft surgery appears to be decreasing

2011-01-26
An analysis of data on more than 45,000 patients who underwent coronary artery bypass graft (CABG) surgery at an academic medical center over the past 30 years finds that the occurrence of stroke after CABG has declined, despite an increase in risk profiles of patients, according to a study in the January 26 issue of JAMA. Stroke is a devastating and potentially preventable complication of CABG surgery. Because it increasingly is being reserved for elderly patients with extensive coronary disease and co-existing conditions, prevalence of stroke after CABG is likely to ...

Cholera vaccination beneficial, post-outbreak

2011-01-26
Cholera vaccination beneficial, post-outbreak Researchers newly report evidence that vaccination against cholera can be beneficial even after an outbreak has begun. Rita Reyburn, Dr. Lorenz von Seidlein, Dr. John Clemens and colleagues at the International Vaccine Institute (IVI) in Seoul, Korea analyze the impact that vaccination could have had on recent outbreaks around the globe in "The case for reactive mass oral cholera vaccinations", and Drs. Dang Duc Anh and Anna Lena Lopez and colleagues at IVI and in Vietnam report on the impact of such "reactive" use of vaccine ...

Study: Get thee to a stroke center

2011-01-26
Hospitals with designated stroke centers are associated with up to 20 percent higher survival rate for patients with ischemic stroke and significantly greater use of acute stroke therapy. That is the conclusion of a study appearing today in the Journal of the American Medical Association which compares treatment and outcomes in stroke care between hospitals in New York State. "The basic premise of stroke centers and stroke care – that coordinated care delivered around a specific disease can likely improve outcomes – is widely accepted," said University of Rochester ...

Report examines life expectancy in US and other high-income nations

2011-01-26
Over the last 25 years, life expectancy in the U.S. has been rising at a slower rate than in many other high-income countries, such as Japan and Australia, despite our spending more on health care than any other nation. EXPLAINING DIVERGENT LEVELS OF LONGEVITY IN HIGH-INCOME COUNTRIES, a new report from the National Research Council, identifies factors that contribute to the U.S. shortfall in life expectancy. ###Reporters who wish to obtain copies should contact the Office of News and Public Information at 202-334-2138 or e-mail news@nas.edu. Advance copies will be available ...
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