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Vitamin D deficiency puts IBD patients at greater risk of osteoporosis

2010-10-19
San Antonio, Texas (October 18, 2010) – Vitamin D deficiency puts patients with Inflammatory Bowel Disease (IBD) at greater risk of osteoporosis, osteopenia and an overall higher rate of abnormal bone density, according to the results of a new study unveiled today at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio, Texas. The study, "Vitamin D Deficiency and Abnormal DEXA Scans in Inflammatory Bowel Disease Patients," found that of the 161 IBD patients in the cohort, reduction in bone density with a diagnosis of osteoporosis ...

Acid reflux, functional dyspepsia have significant impact on disordered sleep

2010-10-19
San Antonio, Texas (October 18, 2010) – The impact of upper GI conditions, like gastroesophageal reflux disease (GERD) and functional dyspepsia, on sleep—and treatments aimed at providing relief to heartburn/acid reflux patients who suffer from disordered sleep—were explored in three new studies related to sleep dysfunction presented today at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio, Texas. Functional dyspepsia is a common, but poorly understood, upper GI condition affecting approximately 10 percent of U.S. adults. ...

Notable racial disparities in diagnosis, treatment and outcomes of colorectal cancer

2010-10-19
San Antonio, Texas (October 18, 2010) – The latest colorectal cancer research presented at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio this week strengthens the growing body of evidence that suggests significant disparity in colorectal cancer (CRC) demographics and outcomes between various races. In the first in a series of studies investigating colorectal cancer disparities that exist between various races, researchers conducted a retrospective analysis of colonoscopies performed in young patients from July 2003 to December ...

Encouraging findings suggest new avenues for treating liver disease in overweight Americans

2010-10-19
San Antonio, Texas, October 18, 2010 – Estimates of the prevalence of liver disease suggest that one‐third of the United States population has non‐alcoholic fatty liver disease (NAFLD). NAFLD is now the most common cause for elevated liver function tests in the United States, a trend related to the obesity epidemic in this country. Non‐alcoholic steatohepatitis (NASH), the progressive form of NAFLD, can lead to cirrhosis and all its complications. Two studies presented at the 75th Annual Scientific Meeting of the American College of Gastroenterology investigated ...

New studies highlight obesity's impact on gastrointestinal health

2010-10-19
San Antonio, Texas (October 18, 2010) – The association between obesity and gastrointestinal-related cancers and coronary artery disease; the link between an overweight or obese body mass index and the severity of Crohn's disease; and whether inflammatory bowel disease is an independent risk factor for coronary artery disease, were among the highlights of new research that was presented this week at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio. Obesity Linked to Increased Liver Cancer Risk, Adenoma Recurrence Although ...

Investment in CRC screening targeting pre-medicare population could cut medicare treatment costs

2010-10-19
San Antonio, Texas (October 18, 2010) – Investment in screening programs that target the pre-Medicare population, individuals aged between 50 and 64, is needed to reduce the costs of colorectal cancer in the Medicare program, according to the results of a new study, "Cost-Savings to Medicare from Increased Colorectal Cancer Screening in the Pre-Medicare Population," unveiled today at the American College of Gastroenterology's (ACG) 75th Annual Scientific meeting in San Antonio, Texas. "With rising chemotherapy costs and aging of the population, the Medicare program will ...

National Stroke Association survey reveals more than half of stroke survivors suffer added burden of little known neurologic condition

2010-10-19
CENTENNIAL, CO – October 18, 2010 – A survey released today by National Stroke Association shows that 53 percent of stroke survivor respondents suffer from symptoms of another neurologic condition called pseudobulbar affect (PBA), a condition thought to be caused by structural damage in the brain due to injury or disease. PBA causes involuntary and unpredictable outbursts of laughing or crying, often in socially inappropriate situations. Even though a significant proportion of stroke survivors suffer from PBA, fewer than one in five are familiar with the condition. Survey ...

Colonoscopy technique increases polyp detection in far reaches of right colon

2010-10-19
San Antonio, Texas, October 18, 2010 – Research exploring the progression of colon polyps to colorectal cancer and evaluating techniques to improve polyp detection was among the clinical science presented at the 75th Annual Scientific Meeting of the American College of Gastroenterology in San Antonio today. The Progression to Colorectal Cancer in Flat Polyps Precancerous growths in the colon known as sessile serrated adenomas (SSA) are found in approximately 1 percent of colonoscopy exams. A sessile serrated ademona is a premalignant flat lesion in the colon thought ...

100-million-year-old mistake provides snapshot of evolution

2010-10-19
Research by University of Leeds plant scientists has uncovered a snapshot of evolution in progress, by tracing how a gene mutation over 100 million years ago led flowers to make male and female parts in different ways. The findings – published this week in the Proceedings of the National Academy of Sciences (PNAS) Online Early Edition – provide a perfect example of how diversity stems from such genetic 'mistakes'. The research also opens the door to further investigation into how plants make flowers – the origins of the seeds and fruits that we eat. In a number of plants, ...

When vertebrae cross dress: How sloths got their long neck

2010-10-19
By examining the development of bones in the vertebral column, limbs, and ribcage, scientists at the University of Cambridge have discovered how sloths evolved their unique neck skeleton. From mice to giraffes, mammals are remarkable in that all but a handful of their 5000 species have exactly seven vertebrae in the neck. Among the few that deviate from this number are three-toed sloths, which may have up to ten ribless vertebrae in the neck. Traditionally, vertebrae above the shoulders that lack ribs are known as cervical or neck vertebrae. Animals such as birds and ...

Removing 2mm around breast cancer tumors prevents residual disease in 98 percent of patients

2010-10-19
Removing an extra two millimetres around an area of invasive breast cancer is sufficient to minimise any residual disease in 98 per cent of patients, according to research published in the November issue of IJCP, the International Journal of Clinical Practice. Surgeons from the Department of Breast Surgery at Good Hope Hospital, Sutton Coldfield, UK, studied 303 women who had undergone breast conserving surgery at the hospital between 2002 and 2008. "Breast conserving surgery followed by radiotherapy is a well-established alternative to breast removal and studies have ...

Drivel on Facebook more valuable than we think

2010-10-19
Superficial contacts on Facebook, apparently unnecessary comments, and banal status updates may be more worthwhile than we think. This is shown in a new report from the National IT User Center. The report also predicts the new social media will ultimately lead to more individual entrepreneurs. Many people are critical of those who collect hundreds of so-called friends on Facebook. Often the majority of these "friends" are old classmates, acquaintances of acquaintances, and the like, relationships that are fundamentally weak. The comments and updates of relatively banal ...

A mystery solved: How genes are selectively silenced

2010-10-19
Our genetic material is often compared to a book. However, it is not so much like a novel to be read in one piece, but rather like a cookbook. The cell reads only those recipes which are to be cooked at the moment. The recipes are the genes; 'reading' in the book of the cell means creating RNA copies of individual genes, which will then be translated into proteins. The cell uses highly complex, sophisticated regulatory mechanisms to make sure that not all genes are read at the same time. Particular gene switches need to be activated and, in addition, there are particular ...

Body's bacteria affect atherosclerosis

2010-10-19
New findings suggesting that bacteria in the mouth and/or intestine can affect the the outcome pathogenesis of atherosclerosis and lead to new treatment strategies, reveals research from the University of Gothenburg, Sweden. The results are to be published in the distinguished journal Proceedings of the National Academy of Sciences, PNAS. "The causes of atherosclerosis have recently become clearer, but we know less about why the plaque in the arteries ruptures and contributes to clot formation," says Fredrik Bäckhed, researcher at the Sahlgrenska Academy's Department ...

Prostate cancer patients treated with robotic-assisted surgery can expect low recurrence of cancer

2010-10-19
A first-ever, long-term study of patients who underwent robot-assisted surgery to remove their cancerous prostates found that nearly 87 percent of them had no recurrence of the disease after five years. The findings were reported in this month's issue of the European Urology journal by a team of Henry Ford Hospital researchers led by Mani Menon, M.D., an internationally recognized pioneer in the use of high-precision surgical robots. In an editorial accompanying the article, the author wrote "it is very clear that the article by Menon et al represents a land mark contribution ...

Researchers increase understanding of genetic susceptibility to psoriasis

2010-10-19
Genetic variants associated with increased susceptibility to psoriasis are reported in five papers published online this week in Nature Genetics. Psoriasis is a chronic and recurrent skin disease, and one of the most prevalent autoimmune diseases, with a global prevalence of 2-3%. One of the studies was led by the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre (BRC) at Guy's and St Thomas' and King's College London and the Wellcome Trust Centre for Human Genetics at Oxford University, and involved multiple UK institutions. The ...

Why are men more susceptible to alcoholism?

2010-10-19
Philadelphia, PA, 18 October 2010 - Alcohol is one of the most commonly abused substances, and men are up to twice as likely to develop alcoholism as women. Until now, the underlying biology contributing to this difference in vulnerability has remained unclear. A new study published in Biological Psychiatry reveals that dopamine may be an important factor. Researchers from Columbia and Yale studied male and female college-age social drinkers in a laboratory test of alcohol consumption. After consuming an alcoholic or non-alcoholic drink, each participant underwent a ...

Better student performance with peer learning

2010-10-19
Engineering students with average grades from upper secondary school can manage difficult courses just as well as students with high grades. At least, if a group of them meet an older student once a week during the first semester to discuss and solve maths problems and other difficult exercises from their courses. This is shown by a new evaluation from the Faculty of Engineering at Lund University of the 'peer learning' sessions, or SI (supplemental instruction), as the method is also known. The SI method is also used at universities in the USA, Canada, Australia, ...

Globalized economy more sensitive to recessions

2010-10-19
By applying the same rules that explain how genomes evolve, Rice University physicists have shown that the world economy is more sensitive to recessionary shocks and recovers more slowly from recessions now than it did 40 years ago, due to increased trade globalization. Their findings are available online and will appear in an upcoming issue of the Physical Review Letters. "Standard economic theory suggests that trade networks with a more modular structure tend to recover more slowly from recessions, but using evolutionary theory we predicted the opposite, and U.N. ...

It is unclear if programs to encourage cycling are effective

2010-10-19
More research and evaluation are needed to determine the most effective community programmes to encourage cycling, says a study published on bmj.com today. The authors, led by Dr David Ogilvie from the Institute of Public Health in Cambridge, say that it is unclear whether community approaches to increase cycling amongst children and adults have anything more than a modest effect. Established research shows that cycling is linked to greater cardio-respiratory fitness in adults and children. And general physical activity reduces the risk of heart disease, type 2 diabetes, ...

NHS reforms could mean more patients seeking treatment abroad, warn experts

2010-10-19
Spain's excellent record on organ donation rates has nothing to do with its presumed consent legislation, say experts in an article published on bmj.com today. Professor John Fabre, from the Department of Hepatology and Transplantation at King's College London, Paul Murphy from the Department of Neuroanaesthesia and Critical Care at the Leeds General Infirmary, and Rafael Matesanz from the Orgaizacion Nacional de Trasplantes in Madrid say that the Spanish example shows that higher rates can be achieved without presumed consent. Spain has the world's highest rate ...

Change in how paramedics use oxygen could reduce deaths

2010-10-19
A change to the way paramedics use oxygen when treating patients with chronic lung disease could cut the death rate in these cases by up to 78%, according to a new study published on bmj.com today. Researchers based in Australia found the risk of death in patients with chronic obstructive pulmonary disease (COPD) was significantly reduced by using titrated (controlled) oxygen therapy instead of the current common approach of high concentration oxygen. High concentration oxygen is used routinely by many paramedics in emergency situations for patients with acute breathlessness ...

New 2010 European Resuscitation Council Guidelines published

2010-10-19
Oxford, UK, 18 October 2010 – Elsevier announces the publication of the 2010 European Resuscitation Council (ERC) Guidelines in the journal Resuscitation. These guidelines are based on an extensive international review of all the science supporting cardiopulmonary resuscitation (CPR), the 2010 International Consensus on CPR Science, which is also published in the current issue of Resuscitation. This year is the 50th anniversary of CPR. Throughout Europe, each year, about 500,000 people have an out-of-hospital sudden cardiac arrest. Less than 10% of these will survive. ...

MU researchers find celebrity journalism may contribute positively to consumer health behaviors

2010-10-19
COLUMBIA, Mo. – Celebrity journalism is often considered to be without merit, discounted due to its sensational details and lack of news value. MU researchers now say that celebrity journalism may be an underappreciated way to communicate health messages. In a recent award-winning paper, Amanda Hinnant, assistant professor of magazine journalism in the University of Missouri School of Journalism, found some readers of celebrity health stories report that the stories have an impact on their own behavior and how they discuss health issues. Amanda Hinnant, assistant professor ...

Call for long-term view on 'dire' funding of biological research databases

2010-10-19
A rethink is needed on the 'dire' situation of funding of databases across biology, researchers say. A paper co-authored by Sabina Leonelli, Research Fellow at Egenis at the University of Exeter, reviews the business models currently used to deal with long-term sustainability of these resources, and suggests a 'global change' in funding policies is necessary. "There is no point investing resources into collecting data, if the development of tools needed to disseminate and interpret those data is not supported. In this sense, building appropriate cyberinfrastructure ...
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