Tet further revealed: Studies track protein relevant to stem cells, cancer
CHAPEL HILL, N.C. – Last year, a research team at the University of North Carolina at Chapel Hill discovered one way the protein Tet 1 helps stem cells keep their pluripotency—the unique ability to become any cell type in the body. In two new studies, the team takes a broad look at the protein's location in the mouse genome, revealing a surprising dual function and offering the first genome-wide location of the protein and its product, 5-hydroxymethylcytosine—dubbed the "sixth base" of DNA.
UNC biochemist Yi Zhang, PhD, whose team conducted the studies, called the findings ...




