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SHIP protein identified as a B-cell tumor suppressor

SHIP protein identified as a B-cell tumor suppressor
2010-10-20
LA JOLLA, Calif., October 18, 2010 – Lymphoma is a cancer of the immune system. White blood cells divide again and again, spreading abnormally throughout the body. Lymphomas can arise from two types of white blood cells, T cells or B cells, which divide uncontrollably when the molecular mechanisms that keep them in check go awry. A new study led by Robert Rickert, Ph.D., professor and director of the Inflammatory Diseases Program at Sanford-Burnham Medical Research Institute (Sanford-Burnham), explores the roles of two enzymes, called SHIP and PTEN, in B cell growth and ...

Professional sports persons should drink more water

Professional sports persons should drink more water
2010-10-20
Top sports persons must always perform to their maximum capacity, making them the most vulnerable to the effects of dehydration. Now, a new study conducted by researchers from the Universidad de Castilla la Mancha (UCLM) reveals that 91% of professional basketball, volleyball, handball and football players are dehydrated when they begin their training sessions. "Dehydration negatively affects sporting performance, even when the level of dehydration is low (such as a 2% loss of body weight through perspiration)", UCLM researcher and author of the article Ricardo Mora-Rodríguez ...

More than 200 new snails of the same genus described in a single study

More than 200 new snails of the same genus described in a single study
2010-10-20
Two world experts in micro molluscs, Anselmo Peñas and Emilio Rolán, have made an unprecedented description in a scientific publication of a combined total of 209 snail species. Commissioned by the National Museum of Natural History in Paris, the study was unveiled in September in the French capital, and it covers the most new species from a single genus of any study to date. "Never have so many species from a single genus, nor even from a single family, been described in one single study", Anselmo Peñas, lead author of the collaborative monograph between the National ...

Study reveals how sex hormones influence right heart function

2010-10-20
In the largest human study to date on the topic, researchers have uncovered evidence of the possible influence of human sex hormones on the structure and function of the right ventricle (RV) of the heart. The researchers found that in women receiving hormone therapy, higher estrogen levels were associated with higher RV ejection fraction and lower RV end-systolic volume — both measures of the RV's blood-pumping efficiency — but not in women who were not on hormone therapy, nor in men. Conversely, higher testosterone levels were associated with greater RV mass and larger ...

Air pollution exposure increases risk of severe COPD

2010-10-20
Long term exposure to low-level air pollution may increase the risk of severe chronic obstructive pulmonary disease (COPD), according to researcher s in Denmark. While acute exposure of several days to high level air pollution was known to be a risk factor for exacerbation in pre-existing COPD, until now there had been no studies linking long-term air pollution exposure to the development or progression of the disease. The research was published online ahead of the print edition of the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. "Our ...

Adiponectin shows potential in blocking obesity-related carcinogenesis

2010-10-20
A research team from Emory University School of Medicine investigated the role between adiponectin and leptin in obesity-related carcinogenesis. Their findings, published in the November issue of Hepatology, suggest that the protein hormone adiponectin has potential for inhibiting the oncogenic actions of leptin, namely in hepatocellular carcinoma (HCC), and could offer a promising therapy for the disease. Obesity is on the rise and is associated with increased risk and progression of a number of cancers including colon, prostate, breast, and liver cancers. The World ...

Visceral adiposity index directly correlated to viral load in genotype 1 chronic hepatitis C

2010-10-20
Researchers at the University of Palermo in Italy provide the evidence that a higher visceral adiposity index score—a new index of adipose dysfunction—has a direct correlation with viral load and is independently associated with both steatosis and necroinflammatory activity in patients with genotype 1 chronic hepatitis C (G1 CHC). Details of this study are available in the November issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD). According to public health surveillance data gathered ...

Experts discuss S-equol data at ninth international symposium on role of soy

2010-10-20
Washington, DC (Oct. 19, 2010) The latest research into the health effects and safety of a soy-based compound called S-equol was described in talks and presentations by experts at a special session on Tuesday, Oct. 19 during the Ninth International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment, held Oct. 16 to 19 in Washington, D.C. S-equol is a compound resulting -- when certain bacteria are present in the digestive track -- from the natural metabolism, or conversion, of daidzein, an isoflavone found in whole soybeans. ...

Experiments find bias in way analysts view firms led by black grads of prestigious universities

2010-10-20
Analysts examining a firm and the qualifications of its top management team discount the educational background of African American managers who graduated from prestigious universities while accepting the qualifications of white managers with the same college credentials, according to two experiments reported in the current issue of Organization Science, a journal of the Institute for Operations Research and the Management Sciences (INFORMS®). "We found that possessing high educational prestige was less beneficial for firms led by African Americans than for firms with ...

Novel regulatory process for T cells may help explain immune system diseases

2010-10-20
CINCINNATI - A newly identified regulatory process affecting the biology of immune system T cells should give scientists new approaches to explore the causes of autoimmunity and immune deficiency diseases. In findings posted online ahead of publication in Proceedings of the National Academy of Sciences (PNAS), scientists at Cincinnati Children's Hospital Medical Center report a novel process of coordinated cellular communications vital to the maintenance of T cells. If the process breaks down, T cells proliferate rapidly and die off. This could disrupt the immune system's ...

Friends share personal details to strengthen relationships in United States, but not in Japan

2010-10-20
In the United States, friends often share intimate details of their lives and problems. However, such self-disclosure is much less common in Japan. A new study by an American researcher living in Japan finds that this may be because of the different social systems in the two countries, and in particular the extent to which there are opportunities to make new friends. "At first, it seemed strange that in Japan, people didn't open up and share a lot about themselves with each other," says Joanna Schug of Hokkaido University. "But Japanese often look at Americans and think, ...

Docs not immune to drug marketing: Study co-authored by York U prof

2010-10-20
TORONTO, October 19, 2010 – Pharmaceutical promotion may cause doctors to prescribe more expensively, less appropriately and more often, according to a new study co-authored by York University professor Joel Lexchin. The findings, published today in the journal, PLoS Medicine, offer a broad look at the relationship between doctors' prescribing habits and their exposure to information provided by drug companies. Researchers analyzed 58 separate studies of this phenomenon from Canada, the United States, Europe and Australia, dating from the 1960s. "Many doctors claim ...

Research brings cure for Parkinson's disease a step closer

Research brings cure for Parkinsons disease a step closer
2010-10-20
An international collaboration led by academics at the University of Sheffield, has shed new light into Parkinson's disease, which could help with the development of cures or treatments in the future. The collaboration, which was led by Professor Peter Redgrave from the University's Department of Psychology, suggests that many of the problems suffered by patients with Parkinson's disease - difficulties in initiating actions, slow laboured movements and tremors – can be understood in terms of damage to control circuits in the brain responsible for habits. The analysis, ...

Culturally inspired mobile phone games help Chinese children learn language characters

2010-10-20
Mobile phone-based games could provide a new way to teach basic knowledge of Chinese language characters that might be particularly helpful in underdeveloped rural areas of China, say researchers in Carnegie Mellon University's Mobile & Immersive Learning for Literacy in Emerging Economies (MILLEE) Project. Earlier this year, researchers reported that two mobile learning games, inspired by traditional Chinese games, showed promise during preliminary tests with children in Xin'an, an underdeveloped region in Henan Province, China. The researchers from Carnegie Mellon, ...

Inhaling nitric oxide eases pain crises in sickle cell patients

Inhaling nitric oxide eases pain crises in sickle cell patients
2010-10-20
AUGUSTA, Ga. – Inhaling nitric oxide appears to safely and effectively reduce pain crises in adults with sickle cell disease, researchers report. A study of 18 patients in Atlanta, Chicago and Detroit showed that the nine inhaling nitric oxide for four hours had better pain control than those receiving only the standard self-administered morphine, said Dr. C. Alvin Head, chairman of the Department of Anesthesiology at the Medical College of Georgia School of Medicine. "This study shows that you can breathe the gas and have less pain, which is the major reason sickle cell ...

Paraquat resistance discovered in major weed

2010-10-20
Scientists at the University of Adelaide have discovered new cases of herbicide resistance in annual ryegrass, one of the world's most serious and costly weeds. For the first time, researchers have found that annual ryegrass has developed resistance to paraquat, the second most important "knockdown" herbicide used by cropping farmers. Weed management experts Dr Peter Boutsalis and Associate Professor Christopher Preston, from the University's Waite Research Institute, made the discovery in samples taken from two separate farming properties near the South Australian ...

How green is your campus?

2010-10-20
Williamsburg, VA —October 19, 2010— Corporations and individuals alike are increasingly focused on "going green," in an attempt to reduce their carbon footprint and impact on the environment. It is questionable whether higher education institutions are adopting sustainable practices at the same rate, despite large consumption rates of energy and water, among other resources. In the first study of its kind, Contemporary Economic Policy presents an article which compares the factors that drive colleges to adopt sustainable practices to the factors that motivate for-profit ...

Inflammatory breast cancer focus of new report

2010-10-20
ATLANTA—October 19, 2010—A rare and deadly form of breast cancer that often goes unrecognized by clinicians and patients alike is the focus of a new report from leading researchers. Inflammatory breast cancer (IBC) has made headlines as an unrecognized and misunderstood form of breast cancer. It has a younger age of onset, progresses rapidly, and has lower overall survival compared to other breast cancers. For the new report, leading researchers led by Massimo Cristofanilli, M.D., of Fox Chase Cancer Center in Philadelphia outline IBC's unique clinical presentation, pathology, ...

Children's best friend

2010-10-20
Montreal, October 19, 2010 – Dogs may not only be man's best friend, they may also have a special role in the lives of children with special needs. According to a new Université de Montreal study, specifically trained service dogs can help reduce the anxiety and enhance the socialization skills of children with Autism Syndrome Disorders (ASDs). The findings published this year in Psychoneuroendocrinology may be a relatively simple solution to help affected children and their families cope with these challenging disorders. "Our findings showed that the dogs had a clear ...

Conserving resources: Producing circuit boards with plasma

Conserving resources: Producing circuit boards with plasma
2010-10-20
Flexible circuits can be found in many devices where space and weight considerations are dominant in the design of electronics: in cars, in cameras and video equipment, in mini-computers for athletes or in inkjet printers. And the market continues to grow: according to the business consultancy Frost & Sullivan, sales in this area will grow to more than $16 billion by the year 2014. At K 2010, the trade fair for plastics in Düsseldorf, Germany, scientists from the IST in Braunschweig will unveil a new reel-to-reel technology for the production of flexible circuits and ...

Consumer sentiment shaped by differing cultural attitudes toward power

Consumer sentiment shaped by differing cultural attitudes toward power
2010-10-20
CHAMPAIGN, Ill. – In the battle of egos, Donald Trump vs. Hugo Chavez might be a draw. But as symbols of power, each resonates differently with different cultures, as cultures nurture different views of what is desirable and meaningful to do with power, according to new research by a University of Illinois marketing expert. Sharon Shavitt says the relation between culture and one's concepts of power emerge from one's cultural orientation, and how that culture shapes one's beliefs, attitudes and goals. "People's views of powerful people and what powerful people are supposed ...

Bacteria gauge cold with molecular measuring stick

2010-10-20
HOUSTON -- (Oct. 19, 2010) -- Some bacteria react to the cold by subtly changing the chemistry of their outer wall so that it remains pliable as temperatures drop. Scientists identified a key protein in this response mechanism a few years ago, but the question of how bacteria sense cold in the first place remained a mystery. Based on a study by scientists at Rice University and Argentina's National University of Rosario, the answer is: They use a measuring stick. The study, published in the September issue of Current Biology, involved a series of intricate experiments ...

Osteoporosis drug builds bone in patients with gum disease

2010-10-20
ANN ARBOR, Mich.---A drug marketed to grow bone in osteoporosis patients also works to heal bone wounds in gum disease patients, a University of Michigan study suggests. "This new approach for the treatment of periodontal disease could allow us to rebuild some of the bone that is lost due to periodontal disease, which until this point has been very difficult to achieve," said Jill Bashutski, clinical assistant professor at the U-M School of Dentistry and first author on the study. "Current treatments to re-grow bone around teeth affected with gum disease have limited ...

A middle class that copes by shopping secondhand

2010-10-20
Conventional wisdom holds that people try to mimic the behavior of the next social class above their own. Except when it comes to shopping at secondhand stores and yard sales, concludes a new study by Brigham Young University sociology students and faculty. The study found that high-income shoppers scour the secondhand market for antiques, but everyone else is trying to stretch the family dollar. "Middle-class shoppers were looking for furniture, some appliances, clothes, things that you could argue are necessities," said BYU sociology professor Ralph Brown. "There's ...

UT professor defines play, discovers even turtles need recess

2010-10-20
Seeing a child or a dog play is not a foreign sight. But what about a turtle or even a wasp? Apparently, they play, too. In fact, according to Gordon Burghardt, a psychology professor at the University of Tennessee, Knoxville, many animals -- not just dogs, cats, and monkeys -- need a little play time. "I studied the behavior of baby and juvenile reptiles for many years and never saw anything that I thought was play. Then I had an epiphany when I saw Pigface, a Nile softshell turtle, batting around a basketball at the National Zoo in Washington, D.C. I realized ...
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