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A leader in Texas water management

A leader in Texas water management
2023-12-01
A University of Texas at Arlington civil engineer is leading a statewide initiative to use more accurate forecasting to guide reservoir storage and release to improve water supply reliability and reduce flood damages. Yu Zhang, a UT Arlington associate professor in the Department of Civil Engineering, is heading a new project—“Advancing Forecast-Informed Drought Planning for the West Gulf Region Through Integration of Climate Forecasts and Predictions of Reservoir Water Balance Predictions”—funded by the National ...

Public gardens contribute to invasives problem

Public gardens contribute to invasives problem
2023-12-01
Botanist Denis Conover does not have to go far to study the growing problem of invasive plants. During an autumn stroll outside his office at the University of Cincinnati, the biology professor pointed out numerous examples of nonnative, invasive species in campus landscaping. “This is winged euonymus, otherwise known as burning bush. And here is Chinese silver grass. It’s a popular ornamental, but the seeds are dispersed by the wind,” he said. And there were many others: English ivy, wintercreeper, Callery pear. For his latest study published in the journal Ecological Restoration, he and his students examined the impact ...

Rett patients receive a new gene therapy treatment at Texas Children’s Hospital and Baylor College of Medicine

2023-12-01
Texas Children’s Hospital, an internationally-recognized, top-ranked children’s hospital and pediatric research center affiliated with Baylor College of Medicine, is the first to deliver a novel gene therapy to treat Rett syndrome in pediatric patients. Two female patients with Rett syndrome were the first children worldwide to receive this promising treatment. This exciting milestone is part of an ongoing first-in-human Phase I/II trial of a new investigational gene therapy, NGN-401, conducted by Neurogene Inc., a clinical-stage company founded to bring life-changing genetic medicines to patients ...

A color-based sensor to emulate skin's sensitivity

A color-based sensor to emulate skins sensitivity
2023-12-01
Robotics researchers have already made great strides in developing sensors that can perceive changes in position, pressure, and temperature – all of which are important for technologies like wearable devices and human-robot interfaces. But a hallmark of human perception is the ability to sense multiple stimuli at once, and this is something that robotics has struggled to achieve. Now, Jamie Paik and colleagues in the Reconfigurable Robotics Lab (RRL) in EPFL’s School of Engineering have developed a sensor that can perceive combinations of bending, stretching, compression, and temperature changes, all using a robust system that boils down ...

SFU researchers sound out Canadian military’s plan to combat ocean noise pollution

2023-12-01
new study from Simon Fraser University researchers examines the Canadian military’s efforts to reduce the impacts of underwater noise pollution on species during training exercises in the Pacific Ocean but caveat that more can still be done. The paper, published today in Marine Policy, takes aim at a report commissioned by the Canadian Department of National Defence (DND) to reduce the effects of noise pollution from military small-arms munitions training within “Whiskey Hotel”, a 330-square-kilometre ...

Coverage of Bruce Willis’ frontotemporal degeneration shows media misconstrues the disease

2023-12-01
A new paper in Innovation in Aging, published by Oxford University Press, shows that a great deal of media coverage of the actor Bruce Willis’ condition, frontotemporal degeneration, was inaccurate, revealing the public’s limited knowledge of the disease. In 2022, Willis’ family released a statement saying that he had been diagnosed with aphasia, an acquired language impairment, and would retire from acting. Ten months later, the family issued another statement indicating doctors had diagnosed Willis with a more specific condition, frontotemporal degeneration. ...

Potential pitfalls when using the Cre-LoxP system in cancer research

Potential pitfalls when using the Cre-LoxP system in cancer research
2023-12-01
“One limitation [of Cre-LoxP], the focus of this editorial, is the potential loss of fidelity of Cre recombinase expression especially in the context of modeling cancer in mice.” BUFFALO, NY- December 1, 2023 – A new editorial paper was published in Oncoscience (Volume 10) on November 14, 2023, entitled, “Be mindful of potential pitfalls when using the Cre-LoxP system in cancer research.” In this new editorial, researchers Piotr Czarnota and Jaroslaw Cisowski from Jagiellonian University discuss Cre-LoxP — a widely used system to conditionally modify gene expression in mouse models of cancer and other diseases.  “It ...

CHOP researchers discover deep structural biology connections that help improve CAR therapy

2023-12-01
Philadelphia, December 1, 2023 – Chimeric Antigen Receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells. Peptide-centric CARs (PC-CARs) rely on specific peptide “barcodes,” which are derived from proteins within the cell created by potentially cancer-causing oncogenes, are designed to find and target cancer cells. These “barcodes” are displayed by human leukocyte antigens (HLAs), which help the immune system distinguish its own proteins from foreign invaders, ...

Can preeclampsia be prevented?

Can preeclampsia be prevented?
2023-12-01
NEWS RELEASE EMBARGOED UNTIL FRI, DEC. 1 -- 2:00 P.M. EASTERN   Contact Colleen McDonald - Sr. Consultant, Earned Media 414.801.3146 | cmcdonald@mcw.edu     Milwaukee, Wis. – Dec. 1, 2023 – Preeclampsia is a mysterious condition that occurs in about one of 10 pregnancies without any early warning signs. After 20 weeks or more of normal blood pressure during the pregnancy, patients with preeclampsia will begin to experience elevated blood pressure and may also have increased levels of protein in their urine due to hypertension reducing the filtering power of the kidneys. Prolonged hypertension due ...

Meditation training can support wellbeing in older adults

2023-12-01
Following an 18-month meditation programme can improve the wellbeing of older adults, finds a new randomised controlled trial by an international team co-led by UCL. The findings, published in PLOS ONE, show that meditation can improve people’s awareness, connection to others, and insight. While the meditation training did not confer significant benefits on two commonly used measures of psychological wellbeing and quality of life, the researchers say their findings may reveal limitations in existing methods of tracking wellbeing. Lead author Marco Schlosser (UCL Psychiatry and University of Geneva) said: “As the global population ...

Research shows human behavior guided by fast changes in dopamine levels

Research shows human behavior guided by fast changes in dopamine levels
2023-12-01
What happens in the human brain when we learn from positive and negative experiences? To help answer that question and better understand decision-making and human behavior, scientists are studying dopamine. Dopamine is a neurotransmitter produced in the brain that serves as a chemical messenger, facilitating communication between nerve cells in the brain and the body. It is involved in functions such as movement, cognition and learning. While dopamine is most known for its association with positive emotions, scientists are also exploring ...

Scientists navigate uncharted waters in fish immunology research

Scientists navigate uncharted waters in fish immunology research
2023-12-01
Upon infection or immunization, all jawed vertebrate species generate proteins called antibodies that bind and neutralize pathogens. Strong and long-lasting antibody responses in warm-blooded species such as mammals are produced in secondary lymphoid microstructures (SLMs) among which germinal centers (GCs) are the centerpiece. Despite the apparent absence of GCs or similar SLMs in cold-blooded vertebrates (e.g., fish), these species can mount significant antibody responses that can persist for several months. Thus, for decades, the outstanding question has remained as to how and where ...

Study explores how pre- and postnatal B-12 vitamins improve breast milk vitamin B-12 levels, which supports infant brain development

2023-12-01
  Babies and children need vitamins, including vitamin B-12, to help their brains and bodies develop and grow. Babies get B-12 from their mothers and can have low levels of B-12 if their mothers had low vitamin levels during pregnancy and breastfeeding. The vitamin B-12 levels of infants strongly depend on maternal levels. Adequacy of vitamin B-12 in breast milk is particularly important for infants during the first six months of life when breastfeeding is highly recommended. Even after the first six months of life, breast milk may continue ...

Botany must feature more prominently on the school curriculum to promote awareness of climate change, study warns

2023-12-01
  Children must be taught more about the importance of plants if education about climate change and sustainability is to be effective, experts have warned. Botany should feature more heavily in the school curriculum, and be a greater focus of educational policy, the study says. It warns neither the importance of plants for sustainability or the threats facing many of them are adequately represented in science education. While the problem has been identified for some time, attempts to address it have often struggled to gain a foothold in science education practice. Dr Bethan Stagg from the University of Exeter and Professor Justin Dillon ...

ADA Forsyth scientists work to bring tissue regeneration to replace root canal treatment

2023-12-01
Cambridge, MA - Want to avoid a root canal? In the future, you might be able to opt for tissue regeneration instead. ADA Forsyth scientists are testing a novel technology to treat endodontic diseases (diseases of the soft tissue or pulp in your teeth) more effectively. The study, “RvE1 Promotes Axin2+Cell Regeneration and Reduces Bacterial Invasion,” which appeared in The Journal of Dental Research, demonstrates regenerative properties of resolvins, specifically Resolvin E1 (RvE1), when applied to dental pulp. Resolvins ...

University of Houston challenges students to solve plastic waste crisis

University of Houston challenges students to solve plastic waste crisis
2023-12-01
Plastics are firmly entrenched in today’s world thanks to their cheap, light and versatile nature, but the downside is that plastic waste continues piling up. Earlier this year, United Nations Secretary-General Antonio Guterres said that every day, the equivalent of over 2,000 garbage trucks full of plastics is dumped into our oceans, rivers and lakes. According to the World Economic Forum, the United States only recycled about 6% of the 40 million tons of plastic waste it generated in 2021. Around the world, about 400 million tons of plastic waste is produced each year. Much of it ends up in landfills, oceans and natural ...

Auburn University invites aspiring physicists to PhD program information meeting

Auburn University invites aspiring physicists to PhD program information meeting
2023-12-01
Auburn University's Department of Physics is hosting a special meeting targeting college students passionate about pursuing a PhD in Physics. This engaging event is set for December 8 at 2 PM Central Time. Interested individuals can join the session virtually via Zoom at https://aub.ie/faKH5W. Studying Physics at Auburn University is an immersive journey into the universe's fundamental principles. Our PhD program offers a robust foundation in physics and promotes groundbreaking research and discovery. Known for small class sizes and personalized ...

Social media influencers may affect more than voter opinions

Social media influencers may affect more than voter opinions
2023-12-01
UNIVERSITY PARK, Pa. — If Thanksgiving dinner conversations have turned into heated political arguments over the past two decades, social media may be to blame. Popular social media figures — or influencers — who create or share distorted political messages may cause political parties to moderate their policies to win over independent voters in general elections but tend to polarize the rest of society, according to researchers who created a model to study how social media may affect election ...

1 in 8 older adults use cannabis products, suggesting need to screen for risks

2023-12-01
More older Americans use cannabis now than before the pandemic, with 12% saying they’ve consumed a THC-containing substance in the past year and 4% saying they do so multiple times a week, according to a new study of people aged 50 to 80. Those who drink alcohol at risky levels have a much higher rate of cannabis use. The new findings, published in the journal Cannabis and Cannabinoids Research by a team from the University of Michigan’s Institute for Healthcare Policy and Innovation, suggest a need for more education and screening of older adults for cannabis-related ...

Study identifies peptide as key mediator in heavy alcohol drinking

2023-12-01
(Boston)—Alcohol is the most common addictive substance in the world. Every year in the U.S. excessive alcohol use costs $249 billion and causes approximately 88,000 deaths, as well as various chronic diseases and social issues. Alcohol use disorder, a highly prevalent, chronic, relapsing disorder, affects more than 14 million people in the U.S. alone, in addition to being severely under-treated, with only three modestly effective pharmacological therapies available.   Chronic exposure to alcohol has been shown to produce profound neuroadaptations in specific brain regions, including the recruitment of key stress neurotransmitters, ultimately ...

New understanding of oobleck-like fluids contributes to smart material design

New understanding of oobleck-like fluids contributes to smart material design
2023-12-01
If you mix cornstarch and water in the right proportions, you get something that seems not-quite-liquid but also not-quite-solid. Oobleck flows and settles like a liquid when untouched, but stiffens when you try to pick it up or stir it with a spoon. The properties of oobleck and other non-Newtonian fluids — including Silly Putty, quicksand, paint, and yogurt — change under stress or pressure and scientists have long struggled to prove exactly why. Now, researchers at the University of Chicago’s Pritzker School of Molecular Engineering (PME) have used piezoelectric nanoparticles, which themselves change in response to pressure, to investigate the fundamental physics of non-Newtonian ...

Brainstorming with a bot

Brainstorming with a bot
2023-12-01
A researcher has just finished writing a scientific paper. She knows her work could benefit from another perspective. Did she overlook something? Or perhaps there's an application of her research she hadn't thought of. A second set of eyes would be great, but even the friendliest of collaborators might not be able to spare the time to read all the required background publications to catch up. Kevin Yager—leader of the electronic nanomaterials group at the Center for Functional Nanomaterials (CFN), a U.S. Department of Energy (DOE) Office of Science User Facility ...

Hip hop dancing promotes awareness of disability rights and performance equality, study shows

2023-12-01
Hip hop dancing can be used to spread awareness of disability rights and help those with sight problems to participate in performance equally, a new study says.   Breakin’ – which is commonly referred to as breakdancing - is good for mobility and helps promote balance and stability as well as wellbeing.   It also offers an important opportunity for people to slow down and to connect with their inner selves, their feelings, their bodies, and their peers, according to researchers. It has been used to treat symptoms of depression, anxiety and PTSD.   Nathan Geering, ...

Urgent work needed to tackle “substantial” digital health inequality, study recommends

2023-12-01
Millions of people are suffering from digital health inequality because of poverty, experts have warned. A new study says urgent work is needed to ensure those from deprived areas can access healthcare as the NHS increasingly turns to the use of apps and online health portals for the provision of healthcare. A team of doctors and academics found a “significant association” between increased poverty and reduced use of digital services. Their modelling estimates that this association accounts for 4.27million patients across England who have not downloaded the NHS app. In October 2022 it was estimated more than 37million patients had activated ...

Unlocking the secret strength of marine mussels

2023-12-01
How do you create strong, yet quick-release connections between living and non-living tissues? This is a question that continues to puzzle bioengineers who aim to create materials that bond together for advanced biomedical applications. Looking to nature for inspiration, the McGill-led research zeroed in on the marine mussel byssus, a fibrous holdfast, which these bivalve mollusks use to anchor themselves in seashore habitats. The byssus attaches to rocky surfaces using an underwater glue, but the other end (the byssus stem root) is firmly anchored within the mussel’s soft living tissue. This area of contact between the living ...
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