Teams of mountaineering mice are helping advance understanding into how evolutionary adaptation to localized conditions can enable a single species to thrive across diverse environments. In a study led by Naim Bautista, a postdoctoral researcher in Jay Storz’s lab at the University of Nebraska–Lincoln, the team took highland deer mice and their lowland cousins on a simulated ascent to 6,000 meters. The “climb” ventured from sea level and the mice reached the simulated summit seven weeks later. Along the way, Bautista tracked how the mice responded to cold stress at progressively lower oxygen levels. “Deer ...

LOGAN, UTAH, USA – Any boomer, gen xer, millennial, gen zer or alpha who’s studied geology has likely gained foundational knowledge from Edwin Dinwiddie McKee’s landmark studies of the Grand Canyon’s sedimentary record – even if they don’t readily recognize McKee’s name. The legendary scientist, who lived from 1906-1984, studied and documented the stratigraphy and sedimentation of Colorado Plateau geology, especially the Grand Canyon’s Cambrian Tonto Group, for more than 50 years. His time-tested ...

A Michigan State University researcher’s new model for studying breast cancer could help scientists better understand why and where cancer metastasizes. Professor https://directory.natsci.msu.edu/Directory/Profiles/Person/103559 who teaches in the MSU Department of Physiology, has been researching the E2F5 gene, of which little is known, and its role in the development of breast cancer. Based on findings from Andrechek’s lab, the loss of E2F5 results in altered regulation of Cyclin D1, a protein linked to metastatic breast tumors after long ...

AUSTIN, Texas — Friends and distinguished alumni of the McCombs School of Business at The University of Texas at Austin inducted four alumni into the school’s Hall of Fame on Nov. 7 at the AT&T Hotel and Conference Center. This year’s honorees are Christopher Bake, BBA ’88; Ray Brimble, B.A. ’74; Bennett Glazer, BBA ’68; and Brien Smith, BBA ’79, MPA '81. McCombs Dean Lillian Mills also recognized 2024 Rising Stars Simeon Bochev, MSF ’13; Michael Ginnings, BBA ’09; and Gerardo Guardado, MBA ’10. The ...

There’s no cure for a fungal disease that could potentially wipe out much of global banana production. Widespread adoption of cement paths, disinfection stations, and production strategies could net 3-4 USD of benefits for each dollar invested in Colombia.  Hundreds of millions of dollars in banana exports from Colombia are at risk due to a fungal disease best known as Tropical Race 4 (TR4). First detected in Asia in the 1990s, the Fusarium fungus that causes the disease arrived in Colombia in 2019, completing its inevitable global spread to South America, the last major banana production continent that remained TR4-free. Researchers are confident ...

New research reveals for the first time how a major Antarctic ice shelf has been subjected to increased melting by warming ocean waters over the last four decades. Scientists from the University of East Anglia (UEA) say the study - the result of their autonomous Seaglider getting accidentally stuck underneath the Ross Ice Shelf - suggests this will likely only increase further as climate change drives continued ocean warming. The glider, named Marlin, was deployed in December 2022 into the Ross Sea from the edge of the sea ice. Carrying a range of sensors to collect data on ocean processes that are important for climate, it was programmed to travel northward into ...

Navigating the intersection of alcohol use and intimate partner violence amongst young couples is not an easy journey, and for bisexual+ couples, the road may be even more winding.   “No study has examined the extent to which alcohol use increases intimate personal violence among bisexual+ young adults or daily experiences unique to them. Our study will look at factors such as minority stressors that may lead to alcohol-related partner violence,” said Meagan Brem, director of the Research for Alcohol and Couple’s Health Lab at Virginia Tech. Alcohol use and intimate partner violence - defined as any action in a ...

A Branco Weiss Fellowship – Society in Science has been awarded to Dr Gergana Daskalova. The fellowship funds Daskalova’s research project “Biodiversity change amidst disappearing human traditions and changing socio-economics”. She joins the Department of Conservation Biology at the University of Göttingen to work together with Professor Johannes Kamp. The five-year fellowship, which is worth over €530,000, will enable Daskalova to investigate the ecological and human fingerprints of land abandonment. Considering the question from both a local and a global perspective, Daskalova’s research will reveal what happens to nature when people leave, ...

Junior Professor Johannes Walker, University of Göttingen, has been awarded an Exploration Grant from the Boehringer Ingelheim Foundation. Walker teaches and carries out research at the Institute for Organic and Biomolecular Chemistry. The award of 180,000 euros will enable Walker and his team to develop new approaches to synthesizing new compounds.   “The aim of our project is to develop new strategies for the synthesis of a particular group of new chemical compounds,’ Walker explains. These compounds are called saturated polycyclic molecules. They are structurally complex ...

A new EU joint research project led by the University of Göttingen will explore how migration, demographic change and current crises are affecting social cohesion and democratic structures in Europe. A key objective is to find out how resilient democratic structures can strengthen local communities in times of profound demographic change. The project “Identities - Migration - Democracy (We-ID)” has been awarded funding of around three million euros over three years by the European Union.   European societies are undergoing a profound demographic transformation: falling birth rates, rising life expectancy and migration are increasingly ...

UC Santa Cruz chemists have discovered a new way to produce biodiesel from waste oil that both simplifies the process and requires relatively mild heat. This discovery has the potential to make the alternative fuel source much more appealing to the massive industrial sectors that are the backbone of the nation’s economy. In 2022, the U.S. transportation sector alone used about 3 million barrels of diesel per day, accounting for about 75% of total consumption of the fuel in this country. That same year, ...

HOUSTON ― The University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Cell Therapy Discovery & Innovation, which will build upon longstanding MD Anderson clinical and research expertise to lead the world in developing and advancing impactful cell therapies for patients in need. The institute will bring together top scientists and clinicians to lead exceptional discovery, translational and clinical research that will deliver new insights in immunology and cell engineering, fueling the creation of transformational new treatments that can be rapidly adapted to address emerging needs in cancer, autoimmune diseases, infections ...

A recent study by researchers from CSIRO and the University of Melbourne has made progress in quantum machine learning, a field aimed at achieving quantum advantage to outperform classical machine learning. Their work demonstrates that quantum circuits for data encoding in quantum machine learning can be greatly simplified without compromising accuracy or robustness. This research was published Sept.12 in Intelligent Computing, a Science Partner Journal. The team’s results, validated through both simulations and experiments on IBM quantum devices, show that their innovative encoding methods reduced circuit ...

A University of Massachusetts Amherst researcher will examine the role of cumulative psychosocial stress – as well as race, ethnicity and gender – among U.S. military personnel to gauge their impact on cardiovascular health and healthcare utilization. The study is funded with a $1 million grant from the Defense Health Agency, part of the Department of Defense (DoD). The findings will help the military develop programs for health promotion and health readiness for active duty and Reserve/National ...

The biomarker human neutrophil lipocalin HNL, which was previously shown to be a useful indicator of bacterial infections, may also in the form of Dimeric HNL be used to effectively monitor the success of antibiotic treatment in sepsis. The first promising results in this regard were published in 2019 and now the research group has confirmed these results in a larger study. The study is published in the journal PLOS ONE. Sepsis, the costliest disease to health care, is a life-threatening condition with high mortality if not diagnosed and ...

November 8, 2024, CLEVELAND: Cleveland Clinic researchers are presenting updated findings from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.   The study team found that the investigational vaccine was generally well tolerated and produced an immune response in most patients. The team described the side effects of the vaccine, showed the highest tolerated dose to date, and presented the immunologic effects of the vaccine. Findings are being presented at the Society for Immunotherapy of Cancer Annual Meeting.   Launched in 2021 and funded by the U.S. Department of Defense, the ongoing ...

The Brain & Behavior Research Foundation (BBRF) is hosting a free webinar, “Intergenerational Effects of Adversity on Mind-Body Health: Pathways Through the Gut-Brain Axis” on Tuesday, November 12, 2024, at 2:00 pm ET. The presenter, Bridget Laura Callaghan, Ph.D., is an Assistant Professor in the Department of Psychology at the University of California, Los Angeles (UCLA). At UCLA, Dr. Callaghan directs the Brain & Body Lab in the Department of Psychology and also heads the Mental Disorders and Pain research theme at the Goodman Luskin Microbiome Center. The webinar host, Jeffrey Borenstein, M.D., is the President ...

Tool use isn’t unique to humans. Chimpanzees use sticks as tools. Dolphins, crows, and elephants are known for their tool-use abilities, too. Now a report in the Cell Press journal Current Biology on November 8, 2024, highlights elephants’ remarkable skill in using a hose as a flexible shower head. As an unexpected bonus, researchers say they also have evidence that a fellow elephant knows how to turn the water off, perhaps as a kind of “prank.” “Elephants are amazing with hoses,” says Michael Brecht ...

When people have an audience watching them, it can change their performance for better or worse. Now, researchers reporting in the Cell Press journal iScience on November 8 have found that chimpanzees’ performance on computer tasks is influenced by the number of people watching them. The findings suggest that this “audience effect” predates the development of reputation-based human societies, the researchers say. “It was very surprising to find that chimpanzees are affected in their task performance by ...

KEY TAKEAWAYS Researchers from Mass General Brigham are leveraging artificial intelligence to help identify the signs of long COVID, track how different symptoms manifest over time, and eliminate alternative explanations for patients’ symptoms. The new approach suggests that 22.8% of the population experience the symptoms of long COVID, a figure that may paint a more realistic picture of the pandemic’s long-term toll. Through analyzing a patient’s history over time, this new AI tool ...

About The Study: In this time-series study, heat waves were associated with increased adverse health events among dually eligible individuals 65 years and older. Without adaptation strategies to address the health-related impacts of heat, dually eligible individuals are increasingly likely to face adverse outcomes.  Corresponding Author: To contact the corresponding author, Hyunjee Kim, PhD, email kihy@ohsu.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamahealthforum.2024.3884) Editor’s Note: Please ...

About The Study: In this cross-sectional study of U.S. patients seeking abortion, many individuals and their households were estimated to incur catastrophic health expenditures, particularly those traveling from out of state. The financial and psychological burdens of abortion seeking have likely worsened after the Dobbs decision, as more people need to cross state lines to reach abortion care. The findings suggest expansion of insurance coverage to ensure equitable access to abortion care, irrespective of people’s state of residence, ...

About The Study: In this cross-sectional study of pregnancy-associated homicide rates, barriers to divorce were associated with higher homicide rates and access to reproductive health care was associated with lower homicide rates. This study highlights the association between state legislation and pregnancy-associated homicide in the U.S., which is important information for policymakers.  Corresponding Author: To contact the corresponding author, Kaitlin M. Boyle, PhD, email kb49@mailbox.sc.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2024.44199) Editor’s ...

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates. Acute liver injury (ALI) caused by acetaminophen (APAP) overdose, hepatic ischemia-reperfusion injury (HIRI), and chronic conditions like nonalcoholic fatty liver disease (NAFLD) and alcohol-associated liver disease (ALD) are influenced by HMGB1-mediated pathways. HMGB1 is released from injured or necrotic liver cells and triggers inflammatory responses. Its circulating levels have been associated with disease severity in liver conditions, marking ...

Cancer remains one of the leading global causes of mortality, with an estimated increase in cases due to lifestyle, environmental, and genetic factors. Despite advancements in treatment, cancer's complexity and the side effects of conventional therapies necessitate alternative approaches. Medicinal plants, long valued for their therapeutic properties, have shown promise in cancer treatment, attributed to their natural phytoconstituents. This review focuses on the anticancer mechanisms of specific medicinal plants and discusses their potential for future therapeutic development. Anticancer Mechanisms of Selected Medicinal Plants Medicinal plants exert anticancer ...