Potential single-dose smallpox and mpox vaccine moves forward
Highlights: An FDA-approved vaccine for smallpox and mpox is effective but causes side effects. The other requires multiple doses. An experimental single-dose vaccine uses the horsepox virus to harness the benefits of both strategies. Previous studies suggest that inoculation with horsepox elicits an antibody response to mpox and provides 100% protection in animal models. New data show that the horsepox virus is significantly more attenuated, or weakened, compared to the virus used in the FDA-approved live virus vaccine. Washington, D.C.—Vaccines that prevent smallpox and mpox come in 2 varieties. One uses a single shot of a live virus but ...
Read the release












