Accelerating Innovation in Medicine - Health Initiative (AIM-HI) is proud to celebrate a significant milestone in the journey of one of its esteemed portfolio companies, Yiviva. A clinical-stage platform biotechnology company, Yiviva has entered into a Memorandum of Understanding (MOU) with AstraZeneca China, a multinational biopharmaceutical leader. AIM-HI exists to support bold new ideas in treating and preventing cancer. So when Yale Professor Yung-Chi Cheng approached us years ago about mining ancient Chinese herbs for modern therapies, we took notice. Other investors ...

DALLAS, Feb. 7, 2024 — Research teams from Northwestern University Feinberg School of Medicine, New York University and Duke University will work together to assess the accuracy of the American Heart Association’s new PREVENTTM risk calculator with funding from the Association’s De-biasing Clinical Care Algorithms project. The American Heart Association, celebrating 100 years of service in 2024, is­ the single largest non-government supporter of heart and brain health research in the U.S. The de-biasing project is funded by a grant from the Doris Duke Foundation to study the role of race and ethnicity in clinical equations and their ...

Geographic sorting along ideological lines is on the rise. Counties and regions of the United States differ in political ideology. But do they differ in personality as well? Further, are people who ‘fit’ their communities healthier, happier, or more highly achieving than those who do not? In the context of these growing divisions and to address this question, a study by Florida Atlantic University’s Kevin Lanning, Ph.D., senior author and a professor of psychology and data science in the Harriet L. Wilkes Honors College on FAU’s John D. MacArthur Campus in Jupiter, and ...

One of the most important components of satellites that enable telecommunication is the waveguide, which is a metal tube for guiding radio waves. It is also one of the heaviest payloads satellites carry into orbit. As with all space technology, reducing weight means reducing the amount of expensive and greenhouse gas-producing fuel it takes to launch a rocket, or increasing the number of devices carried by the same rocket to space. Researchers from Drexel University and the University of British Columbia are trying to lighten the load by creating and testing a waveguide made ...

More than half of Americans do not currently meet the daily recommendation of 5–7 ounce equivalents^ of nuts and seeds per week.1 One possible contributor to such low intakes of tree nuts could be a fear that the calories or fat composition of tree nuts leads to weight gain. For example, past studies suggest that up to 87% of Americans think eating nuts can lead to weight gain due to their dietary fat content2 despite scientists confirming that eating nuts every day, including pistachios,3 can be an achievable and simple strategy to ...

A more accurate way of identifying underground nuclear tests, including those conducted in secret, has been developed by researchers at The Australian National University (ANU).   The new method could help international observers better identify tests carried out by countries or actors known to possess nuclear weapons, as well as providing new information about those suspected of being armed.   According to lead author Dr Mark Hoggard, in the aftermath of the Cuban Missile Crisis and Partial Test Ban Treaty in the 1960s, testing of nuclear ...

DALLAS, Feb. 6, 2024 — Five promising scientific researchers will advance their work to better understand and treat the most common birth defect in the U.S., congenital heart defects (CHDs), thanks to joint financial support from the American Heart Association and The Children’s Heart Foundation's Congenital Heart Defect Research Awards program. To date, the American Heart Association, celebrating 100 years of lifesaving service and devoted to a world of healthier lives for all, and The Children’s Heart Foundation, dedicated to funding congenital heart defect research, have ...

HOUSTON – (Feb. 7, 2024) – Artificial intelligence is good at many tasks involving data in the form of text, audio and images, including face recognition and text summarization. “AI is an amazing tool and has been extended over less conventional domains, such as climate data defined on spheres (representing the Earth) and traffic data defined on road networks,” said Santiago Segarra, assistant professor of electrical and computer engineering and statistics. With his five-year, $599,138 CAREER Award from the National Science Foundation, Segarra intends to study the use of graphs to represent these ...

Whether it’s singing in a choir, playing the living room piano, joining in hymns at church, or just whistling along with the radio, a new poll finds that nearly all older adults say music brings them far more than just entertainment. Three-quarters of people age 50 to 80 say music helps them relieve stress or relax and 65% say it helps their mental health or mood, according to the new results from the University of Michigan National Poll on Healthy Aging. Meanwhile, 60% say they get energized or motivated ...

Sewage sludge is the solid waste resulting from wastewater treatment. According to data from the Ministry for the Ecological Transition and the Demographic Challenge, 1.2 million tons of this waste were produced in Spain in 2021 alone, and its management is a growing problem. Although some of it may have agricultural applications, such as being used as fertilizer after composting, its high concentration of metals limits its use, generating environmental problems. A new study has managed to give this waste a second life, turning it into activated carbon, a product boasting ...

Although change-oriented behaviors are critical to high quality public service delivery, encouraging employees to embrace and pursue change in the public sector is difficult. Even with sufficient job autonomy–the principal antidote to resistance to change in the public sector literature–public servants may still lack the incentives, skills, information, and sense of security necessary to engage in proactive change-oriented behavior. Consequently, while job autonomy is undoubtedly important, it alone is not enough, as demonstrated by the many cases in which autonomy fails to lead to change and work process improvements. Given the importance of attitudes ...

For the first time, a hydrogel material made of nanocellulose and algae has been tested as an alternative, greener architectural material. The study, from Chalmers University of Technology in Sweden and the Wallenberg Wood Science Center, shows how the abundant sustainable material can be 3D printed into a wide array of architectural components, using much less energy than conventional construction methods. The construction industry today consumes 50 percent of the world’s fossil resources, generates 40 percent of global waste and causes 39 percent of global carbon dioxide emissions. There is a growing line of research into biomaterials and their applications, in ...

When it comes to making fuel from plants, the first step has always been the hardest — breaking down the plant matter. A new study finds that introducing a simple, renewable chemical to the pretreatment step can finally make next-generation biofuel production both cost-effective and carbon neutral. For biofuels to compete with petroleum, biorefinery operations must be designed to better utilize lignin. Lignin is one of the main components of plant cell walls. It provides plants with greater structural integrity and resiliency from microbial attacks. However, these natural properties of lignin also make it difficult to extract and utilize ...

The Sun’s polar regions were the most active emitting high energy radiation during the previous solar maximum, an imbalance yet to be explained, and reported for the first time in a study led by a researcher of the Faculty of Sciences of the University of Lisbon (Ciências ULisboa) (Portugal). The Sun shines brightly in the visible light, but how does it look like at the highest energies of the electromagnetic radiation? The Sun’s picture taken in gamma rays is a deadly sight, luckily blinded by the Earth’s atmosphere and only seen from space. Each photon carries a billion times more energy than its ultraviolet sibling. How does the Sun’s regular gamma rays’ ...

A major challenge to developing better neural prostheses is sensory encoding: transforming information captured from the environment by sensors into neural signals that can be interpreted by the nervous system. But because the number of electrodes in a prosthesis is limited, this environmental input must be reduced in some way, while still preserving the quality of the data that is transmitted to the brain. Demetri Psaltis (Optics Lab) and Christophe Moser (Laboratory of Applied Photonics Devices) collaborated with Diego Ghezzi of the Hôpital ophtalmique Jules-Gonin – Fondation Asile des Aveugles (previously Medtronic Chair in Neuroengineering at EPFL) to apply machine ...

A study led by researchers at the Nagoya University Museum in Japan may change how we understand the cultural evolution of Homo sapiens at the time of their dispersal across Eurasia about 50,000 to 40,000 years ago. These findings challenge traditional beliefs about the timing and nature of cultural transitions during this critical period in human history.  Published in Nature Communications, the researchers’ insights into stone tool technology suggest that the commonly held view of a ‘revolution’ in culture and technology that allowed anatomically modern humans to outcompete ...

Forests, which cover a third of Earth's land surface, are pivotal in carbon storage and the water cycle, though the full scope of their impact remains to be fully understood. In a new study published in Nature Communications, researchers from Stockholm University and international colleagues provide new insights into the complex role forests play in the climate system and water cycle.  The research, involving scientists from 11 institutions across five countries, including Sweden, the UK, Finland, Germany, and Brazil, highlights the intricate relationship between forests, particularly their emission ...

Capsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is approved for the treatment of nerve (or neuropathic) pain. In a real-world study published in Pain Practice that included 97 outpatients in Germany diagnosed primarily with neuropathic back pain, postoperative/posttraumatic neuropathic pain, or postherpetic neuralgia (shingles pain), patients appeared to benefit from multiple HCCP applications. Among the ...

An analysis of relevant published studies indicates that across all ages, food allergy negatively affects individuals’ quality of life to a greater extent in females than in males. The analysis, which is published in Clinical and Experimental Allergy, included 34 studies. In the studies, women and the parents of girls tended to report a greater impact of food allergy on health-related quality of life than men or parents of boys. Evidence also showed that improvements in quality of life over the course of treatment for food allergy can be different for males and females, with weak evidence suggesting that male children may experience more improvements ...

A recent analysis of data from nearly all World Health Organization member states clearly demonstrates a link between air pollution and mortality from cardiovascular diseases, with more of such deaths associated with air pollution in low-income countries compared with high-income countries. In all 183 countries included in the Chronic Diseases and Translational Medicine study, ischemic heart disease-related deaths attributed to air pollution were higher than stroke-related deaths caused by air pollution. In 2019, outdoor air pollution caused 16 ischemic heart disease-related deaths per 100,000 people in high-income countries compared with 70 per 100,000 in low-income countries. Also, in ...

A study published in the Journal of Field Robotics assessed the world’s first unmanned machine designed for autonomous forestry operations. Investigators demonstrated that using computer vision, autonomous navigation, and manipulator control algorithms, their newly developed machine can safely, accurately, and efficiently pick up logs from the ground and maneuver through various forest terrains without the need for human intervention. The research represents a significant milestone in the field of autonomous outdoor robotics, which could reduce the need for human labor, thereby increasing productivity and reducing labor costs, while ...

Researchers are actively working on non-flammable solid electrolytes as a safer alternative to liquid electrolytes commonly found in lithium-ion batteries, which are vulnerable to fires and explosions. While sulfide-based solid electrolytes exhibit excellent ionic conductivity, their chemical instability with high-voltage cathode materials necessary for high-energy-density batteries has impeded their commercial viability. Consequently, there has been a growing interest in chloride-based solid electrolytes, which are stability in high-voltage conditions due to their strong bonding ...

COLUMBUS, Ohio – Keeping track of blood pressure, cholesterol and blood sugar levels can help identify risk factors for heart disease. However, a national survey by The Ohio State University Wexner Medical Center found that while many adults know their childhood address or best friend’s birthday, less than half know their blood pressure or ideal weight, and fewer than 1 in 5 know their cholesterol or blood sugar levels.    “Recognizing heart disease risk factors early and adequately treating ...

In patients with major depression disorder it is, thanks to use of artificial intelligence, now possible to predict within a week whether an antidepressant will work. With the help of an AI algorithm, a brain scan and an individual's clinical information, researchers from Amsterdam UMC and Radboudumc could see up to 8 weeks faster whether or not the medication would work. The results of this study are published today in the American Journal of Psychiatry. "This is important news for patients. Normally, ...

As a predator of soil microorganisms, nematodes respond rapidly to changes in soil environment, which can reflect climate conditions, ecosystem succession status, nutrient cycling and soil ecosystem health. In agroecosystems, nitrogen and phosphate fertilizers are often applied in large quantities. Therefore, studying the effect of nitrogen and phosphorus addition on soil nematode communities is helpful to understand how nitrogen and phosphorus addition affects the growth and development of crops in farmland ecosystems. This study demonstrates that the addition of nitrogen and phosphorus significantly ...