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Science 2010-09-04

Edible nanostructures

Sugar, salt, alcohol and a little serendipity led a Northwestern University research team to discover a new class of nanostructures that could be used for gas storage and food and medical technologies. And the compounds are edible. The porous crystals are the first known all-natural metal-organic frameworks (MOFs) that are simple to make. Most other MOFs are made from petroleum-based ingredients, but the Northwestern MOFs you can pop into your mouth and eat, and the researchers have. "They taste kind of bitter, like a Saltine cracker, starchy and bland," said Ronald ...
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Low grades in adolescence linked to dopamine genes
Science 2010-09-04

Low grades in adolescence linked to dopamine genes

The academic performance of adolescents will suffer in at least one of four key subjects –– English, math, science, history –– if their DNA contains one or more of three specific dopamine gene variations, according to a study led by renowned biosocial criminologist Kevin M. Beaver of The Florida State University. The research sheds new light on the genetic components of academic performance during middle and high school, and on the interplay of specific genes and environmental factors such as peer behavior or school conditions. "We believe that dopaminergic genes ...
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GEN reports on the greening of the life sciences
Environment 2010-09-04

GEN reports on the greening of the life sciences

New Rochelle, NY, September 1, 2010—Biopharmaceutical firms and other life science organizations are taking definitive steps toward creating greener working environments and developing more sustainable operations, reports Genetic Engineering & Biotechnology News (GEN). This promising trend was made clear through a series of presentations and panel discussions that took place at GEN's (www.genengnews.com/gen-articles/biopharma-s-going-green/3381), "GreenBioPharma" conference, which was recently held in Philadelphia. "The main message that emerged from our meeting was that ...
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Medicine 2010-09-04

Sight-saving research halted by stem cell ruling

The Association for Research in Vision and Ophthalmology (ARVO), a professional organization of member scientists, opposes the Federal District Court injunction that froze federal funding for human embryonic stem cell (hESC) research. ARVO is troubled by this barrier to research that has the potential to restore sight and mitigate eye damage. ARVO members investigate hESC therapies for treating diseases such as age-related macular degeneration (AMD), diabetic retinopathy, glaucoma and corneal disease, along with studies related to eye tissue transplantation, regeneration ...
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Engineering 2010-09-04

Scientists identify molecules involved in touch and other mechanically activated systems

LA JOLLA, CA – September 2, 2010 – Scripps Research Institute scientists have identified two proteins with potential to be important targets for research into a wide range of health problems, including pain, deafness, and cardiac and kidney dysfunction. The study was published in Science Express, the advanced, online edition of the journal Science, on September 2, 2010. In the study, the Scripps Research scientists identify two proteins, which they named Piezo1 and Piezo2 from the Greek meaning "pressure," involved in the cellular response to mechanical stimulation. ...
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Science 2010-09-04

Test-tube calf embryos more likely to survive Texas summers

Studies have shown that heat-stressed dairy cows suffer from damage to their ovarian follicles. Moreover, the eggs produced by the damaged follicles may also be damaged, said Dr. Todd Bilby, Texas AgriLife Extension Service dairy specialist. Worse, after becoming heat-stressed, other studies have shown the eggs she ovulates for the next 40 or 50 days are likely to be damaged as well, according to Bilby. Bilby and his graduate student, Brandi Stewart, have found a way to double pregnancy rates during the summer and increase the number of heifers born as compared with ...
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Caltech chemists develop simple technique to visualize atomic-scale structures
Physics 2010-09-04

Caltech chemists develop simple technique to visualize atomic-scale structures

PASADENA, Calif.—Researchers at the California Institute of Technology (Caltech) have devised a new technique—using a sheet of carbon just one atom thick—to visualize the structure of molecules. The technique, which was used to obtain the first direct images of how water coats surfaces at room temperature, can also be used to image a potentially unlimited number of other molecules, including antibodies and other biomolecules. A paper describing the method and the studies of water layers appears in the September 3 issue of the journal Science. "Almost all surfaces have ...
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Medicine 2010-09-04

LSUHSC pediatric weight expert provides obesity trinity answers

New Orleans, LA – In a first person paper published in the August 27, 2010 issue of Childhood Obesity, Dr. Melinda Sothern, Director of Health Promotion and Professor of Public Health at LSU Health Sciences Center New Orleans, provides three ways to de-program the 1950s obesity trinity underlying the current obesity epidemic in the United States and protect future generations from its health consequences. "The combination of prenatal tobacco use, infant formula, and frequent pregnancies— i.e., the obesity trinity—synergistically created the first generation of nutritionally ...
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Technology 2010-09-04

UCSF unveils model for implantable artificial kidney to replace dialysis

UCSF researchers today unveiled a prototype model of the first implantable artificial kidney, in a development that one day could eliminate the need for dialysis. The device, which would include thousands of microscopic filters as well as a bioreactor to mimic the metabolic and water-balancing roles of a real kidney, is being developed in a collaborative effort by engineers, biologists and physicians nationwide, led by Shuvo Roy, PhD, in the UCSF Department of Bioengineering and Therapeutic Sciences. The treatment has been proven to work for the sickest patients using ...
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NASA catches heavy rainfall happening in Category 4 Earl as it approaches the US
Space 2010-09-04

NASA catches heavy rainfall happening in Category 4 Earl as it approaches the US

Hurricane Earl is still a powerful category four hurricane on the Saffir-Simpson Scale as it approaches the North Carolina coast today. NASA's Tropical Rainfall Measuring Mission (TRMM) satellite observed the high rates rain was falling within Earl, in some areas more than 2 inches per hour. Today, the Global Hawk unmanned aircraft is also flying into the eye of Hurricane Earl at altitudes of 60,000 feet to gather information about the storm. Hurricane Earl became the most powerful hurricane of the 2010 Atlantic season early on September 2 when its sustained winds reached ...
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Physics 2010-09-04

Laser-based missile defense for helicopters being developed

ANN ARBOR, Mich.---Protecting helicopters in combat from heat-seeking missiles is the goal of new laser technology created at the University of Michigan and Omni Sciences, Inc., which is a U-M spin-off company. "Battlefield terrain in places like Afghanistan and Iraq can be so rough that our troops have often had to rely on helicopters, and they can be easy targets for enemies with shoulder-launched missiles," said Mohammed Islam, a professor in the Department of Electrical Engineering and Computer Science. "Our lasers give off a signal that's like throwing sand in ...
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Bermuda in warnings as the GOES-13 Satellite catches Fiona approaching
Space 2010-09-04

Bermuda in warnings as the GOES-13 Satellite catches Fiona approaching

Bermuda has warnings up as Tropical Storm Fiona approaches, and GOES-13 satellite imagery from today shows that Fiona, although packing a punch, is a much smaller system that her brother, the Category 4 Hurricane Earl. A tropical storm warning is in effect for Bermuda today, Sept. 2, as tropical storm force winds are expected there by late Friday. Bermuda can expect between 1 to 3 inches of rainfall from Fiona. When the Geostationary Operational Environmental Satellite called GOES-13 captured a visible image of Tropical Storm Fiona approaching Bermuda this afternoon ...
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Science 2010-09-04

Cigarette smoke may contribute to lung inflammation through a new chemical pathway

BIRMINGHAM, Ala. – Cigarette smoke shuts off a key enzyme in airways that regulates the body's response to inflammation, according to findings from the University of Alabama at Birmingham published online today at Science Express. The UAB researchers say smoke inhibits the enzyme, called Leukotriene A4 Hydrolase (LTA4H), causing it to fail in its job of shutting down white blood cells following a successful response to inflammation. The team says the research study identified a previously unknown substrate of LTA4H called proline-glycine-proline (PGP). In a normal ...
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Medicine 2010-09-04

New model may simplify high-dose radiosurgery planning

COLUMBUS, Ohio – There is yet no straightforward way to determine the optimal dose level and treatment schedules for high-dose radiation therapies such as stereotactic radiation therapy, used to treat brain and lung cancer, or for high-dose brachytherapy for prostate and other cancers. Radiation oncologists at the Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) may have solved the problem by developing a new mathematical model that encompasses all dose levels. Typically, radiation ...
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Medicine 2010-09-04

American Society for Biochemistry and Molecular Biology reacts to stem-cell ruling

BETHESDA, Md., Sept. 2, 2010 – The American Society for Biochemistry and Molecular Biology expressed its disapproval and disappointment this week in response to the Aug. 23 ruling in the U.S. District Court for the District of Columbia that granted a preliminary injunction barring federal funding of embryonic stem-cell research. In a statement, the society said the decision, which came in response to a lawsuit filed by two adult stem-cell researchers, effectively halts human embryonic stem-cell research in the United States and "represents a crossroads in American scientific ...
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Science 2010-09-04

Report: Discovery networks hostage-taking a rare terror event

COLLEGE PARK, Md. – A new report by terrorism researchers at the University of Maryland concludes that the deadly hostage-taking incident at the Discovery Communications headquarters in suburban Washington, D.C. meets the criteria of a terrorist act – a rare one for media organizations and the nation's capital region. Hostage-taking, though, is a familiar pattern in capital-region terror, the researchers add. The report from the University of Maryland's START Center – the federally funded National Consortium for the Study of Terrorism and Responses to Terrorism – also ...
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NASA sees Depression Nine become Gaston then back to a depression
Space 2010-09-04

NASA sees Depression Nine become Gaston then back to a depression

Tropical Depression Nine strengthened yesterday into Tropical Storm Gaston, but today it ran into dry and stable air and weakened back into a depression again. When NASA's Aqua satellite flew over Gaston early this morning, Sept. 2 at 0423 UTC (12:23 a.m. EDT), the infrared image taken from the Atmospheric Infrared Sounder (AIRS) instrument showed that Tropical Depression Gaston seemed to have a compact circulation with some high, cold thunderstorm cloud tops around its center of circulation. Those clouds reached so high into the troposphere that they were colder than ...
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Iowa State chemists discover method to create high-value chemicals from biomass
Science 2010-09-04

Iowa State chemists discover method to create high-value chemicals from biomass

AMES, Iowa – Iowa State University researchers have found a way to produce high-value chemicals such as ethylene glycol and propylene glycol from biomass rather than petroleum sources. Walter Trahanovsky, an Iowa State professor of chemistry who likes to write out the chemical structures of compounds when he talks about his science, was looking to produce sugar derivatives from cellulose and other forms of biomass using high-temperature chemistry. And so he and members of his research group studied the reactions of cellulosic materials in alcohols at high temperatures ...
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Medicine 2010-09-04

Children who eat vended snack foods face chronic health problems, poor diet

ANN ARBOR, Mich. — School children who consume foods purchased in vending machines are more likely to develop poor diet quality – and that may be associated with being overweight, obese or at risk for chronic health problems such as diabetes and coronary artery disease, according to research from the University of Michigan Medical School. The study also looked at foods sold in school stores, snack bars and other related sales that compete with USDA lunch program offerings and found that these pose the same health and diet risks in school-aged children. "The foods that ...
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NASA satellite sees Tropical Storm Kompasu transitioning over Korea and China
Space 2010-09-04

NASA satellite sees Tropical Storm Kompasu transitioning over Korea and China

NASA's Terra satellite captured the changing Tropical Storm Kompasu over Korea and China very early today, as it makes its way east to northern Japan. It is becoming extratropical. The Moderate Resolution Imaging Spectroradiometer (MODIS) instrument aboard NASA's Terra satellite captured a visible image of Tropical Storm Kompasu at 02:15 UTC on Sept. 2 (10:15 p.m. EDT Sept. 1) as it was moving over Korea and China. The storm appeared disorganized as there was no visible center of circulation. The Joint Typhoon Warning Center, the organization that forecasts tropical ...
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Medicine 2010-09-04

Novartis and collaborators discover novel antimalarial drug candidate

Singapore, September 3, 2010 — Novartis announced today that scientists at the Novartis Institute for Tropical Diseases (NITD), in collaboration with researchers from the Genomics Institute of the Novartis Research Foundation (GNF), the Swiss Tropical and Public Health Institute and The Scripps Research Institute have discovered a novel compound that shows promise as a next generation treatment for drug resistant malaria. Major support for the project was provided by the Wellcome Trust, the Medicines for Malaria Venture (MMV), A*STAR, Singapore and the U.S. government. Published ...
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Medicine 2010-09-04

Induced pluripotent stem cell retain an inactivated X chromosome

Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell researchers at UCLA have found. The finding could have implications for studying X chromosome-linked diseases such as Rett syndrome, caused by mutations in a gene located on the X chromosome. The findings differ from those seen in mouse skin cells that are reprogrammed into iPS cells, in which the inactive X chromosome reactivates, said Kathrin Plath, senior author ...
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Science 2010-09-04

Race, insurance status cited in uneven death rates among pedestrians hit by cars

Uninsured minority pedestrians hit by cars are at a significantly higher risk of death than their insured white counterparts, even if the injuries sustained are similar, new research from Johns Hopkins suggests. The death rate disparity is compounded by the fact that minority pedestrians are far more likely than white pedestrians to be struck by motor vehicles, according to a study published in the August issue of the journal Surgery. "It's a double whammy," says Adil H. Haider, M.D., M.P.H., an assistant professor of surgery at the Johns Hopkins University School ...
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Science 2010-09-04

Yale develops new animal model for hemophilia A

Researchers at Yale School of Medicine have developed a new animal model for studying hemophilia A, with the goal of eventually treating people with the disorder. Hemophilia A, a hereditary defect that prevents blood from clotting normally, is caused by a variety of mutations in the factor VIII gene. Published online in the Journal of Thrombosis and Haemostasis, the study aimed to provide a better understanding of hemophilia A, according to first author and veterinarian Carmen Jane Booth, assistant professor of comparative medicine, and co-director of Mouse Research Pathology ...
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Medicine 2010-09-04

Non-invasive therapy significantly improves depression, UCLA researchers say

Major depression is a common and disabling brain condition marked not only by the presence of depressed mood but also by its effects on sleep, energy, decision-making, memory and thoughts of death or of suicide. Major depression affects 15 million adults in the U.S., and the World Health Organization projects that by 2020, it will be the largest contributor to disability in the world after heart disease. While antidepressants have helped many to recover and resume their lives, only 30 percent of patients will experience full remission with the first medication they ...
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