Some cancer cells just won’t commit: Why that might be good news for neuroblastoma cancer patients
2025-06-24
Neuroblastoma is a cancer that affects the sympathetic nervous system of children. It is unusual among cancers because it shows a range of outcomes: from aggressive, potentially fatal progression to a unique phenomenon where the tumor spontaneously regresses even without treatment.
Identifying why some patients regress and others don’t could help thousands of patients.
A research group led by Nagoya University believes that the answer may lie in the “uncommitted” state of some neuroblastoma cells. In mice bred to have tumors that were presumed to regress, they discovered a population of “uncommitted" cells that ...
Strategic choices behind accounting standards unveiled in new study
2025-06-24
New study explores why foreign firms listed in the U.S. choose between IFRS and U.S. GAAP. The research finds that firms strategically weigh the flexibility of financial reporting and the costs of compliance, rather than following the common standards in their listing jurisdiction. These insights help explain the real motivations behind financial disclosure decisions and offer guidance for regulators and investors alike.
A new study by Dr. Heylel-li Biton of the Hebrew University Business School sheds light on a long-standing question in global finance: Why do foreign firms listed in the United ...
New 3D modeling method quantifies light-shading impact of freshwater microalgae
2025-06-24
In a groundbreaking study, researchers from the HUN-REN Centre for Ecological Research have developed a novel three-dimensional modeling method that accurately quantifies how microalgae affect underwater light conditions—one of the most critical factors in aquatic ecosystem health.
Published in Water Research, the study addresses a longstanding challenge in hydrobiology: measuring the projected area—the light-blocking surface—of diverse microalgae species, many of which form colonies ...
USPSTF recommendation statement on screening for intimate partner violence and caregiver abuse of older or vulnerable adults
2025-06-24
Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians screen for intimate partner violence in women of reproductive age, including those who are pregnant and postpartum. The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for caregiver abuse and neglect in older or vulnerable adults. Intimate partner violence affects millions of U.S. residents across the lifespan and is often unrecognized. Abuse of older or vulnerable adults by a caregiver or someone else they may trust is common and can result in ...
E-cigarette and cannabis social media posts and adolescent substance use
2025-06-24
About The Study: In this survey study of California adolescents, exposure to e-cigarette or cannabis posts was associated with adolescent e-cigarette, cannabis, or dual use. Improvement of social media community guidelines and greater policy attention to co-use and marketing of e-cigarettes and cannabis may help prevent youth substance use.
Corresponding Author: To contact the corresponding author, Julia Vassey, PhD, email vassey@usc.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jamanetworkopen.2025.17611)
Editor’s Note: Please ...
Breast cancer incidence trends in older US women by race, ethnicity, geography, and stage
2025-06-24
About The Study: In this population-based cross-sectional analysis of breast cancer incidence trends among older U.S. women, racial and ethnic as well as stage-specific patterns differed across age groups, highlighting the importance of disaggregating breast cancer incidence rates into age groups better aligned with screening guidelines. Future research is needed to directly examine the contribution of screening patterns to these trends and their impact on breast cancer mortality.
Corresponding Author: To contact the corresponding author, Erica J. Lee Argov, MPH, email ejl2152@cumc.columbia.edu.
To access the embargoed study: Visit our For The Media website at this link ...
Charging devices with indoor lighting
2025-06-24
WASHINGTON, June 24, 2025 — When you think of solar panels, you usually picture giant cells mounted to face the sun. But what if “solar” cells could be charged using fluorescent lights?
Perovskite solar cells (PeSCs) have emerged as a lower-cost, higher-efficiency alternative to traditional silicon solar cells due to their material structure and physical flexibility. Their large power conversion efficiency rate (PCE), which is the amount of energy created from the amount of energy hitting the cell, makes PeSCs well suited to converting lower light sources into energy.
In APL Energy, by AIP Publishing, researchers from National Yang Ming Chiao Tung University in Taiwan ...
Organ-chips may help unlock the mystery of ALS
2025-06-24
Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.
In a study published in the peer-reviewed journal Cell Stem Cell, investigators detail how they created “ALS on a chip” and the clues the specialized laboratory chip has already produced about nongenetic causes of the disease, also known as Lou Gehrig’s disease.
The work builds ...
E-cigarette and cannabis social media posts pose risks for teens, study finds
2025-06-24
Teens who see social media posts showing cannabis or e-cigarettes, including from friends and influencers, are more likely to later start using those substances or to report using them in the past month, according to surveys done by researchers at the Keck School of Medicine of USC. Viewing such posts was linked to cannabis use, as well as dual use of cannabis and e-cigarettes (vapes). Dual use refers to youth who have used both cannabis and e-cigarettes at some point. The results were just published in JAMA Network Open.
The findings come amid a decline in youth e-cigarette use, reported in 2024 by the U.S. Food ...
Brains over bots: why toddlers still beat AI at learning language
2025-06-24
Even the smartest machines can’t match young minds at language learning. Researchers share new findings on how children stay ahead of AI - and why it matters.
If a human learned language at the same rate as ChatGPT, it would take them 92,000 years. While machines can crunch massive datasets at lightning speed, when it comes to acquiring natural language, children leave artificial intelligence in the dust.
A newly published framework in Trends in Cognitive Sciences by Professor Caroline Rowland of the Max Planck Institute for Psycholinguistics, in collaboration with colleagues at the ESRC LuCiD Centre in the UK, presents a novel framework to explain how children ...
A small reaction space has a big impact on polymer chemistry
2025-06-24
Tokyo, Japan – Mimicking the incredible skill of mother nature is never easy, especially when trying to match the remarkable chemical processes that take place in living organisms. Living systems, like cells, can carry out chemical reactions in very small spaces, sometimes involving single molecules. For many years, researchers have attempted to emulate this to allow for the manufacturing of specialized chemical compounds, but with limited success.
However, new research published in the Journal of the American Chemical Society highlights the development of a new tool that assists with controlling chemical reactions. ...
Small molecule treatment could make islet transplantation therapy more effective
2025-06-24
A pretreatment step could help transplanted pancreatic islets survive longer in patients with type 1 diabetes, according to a new preclinical study from Weill Cornell Medicine investigators. One combination of small molecules extended the cells’ lives in female mice, and adding two molecules to the mixture boosted cell survival in male mice.
The findings, published on June 24 in Cell Stem Cell, could allow physicians to treat more patients with fewer cells.
In type 1 diabetes, autoimmune cells attack the pancreatic islets, destroying ...
Food allergies at summer camp: The cost-effective solution to keep kids safe
2025-06-24
Going off to summer camp can be a scary experience for children, but it can be even more nerve-wracking for parents of kids with food allergies. New UVA Health research reveals the most cost-effective way to keep those children safe.
For most summer camps, stocking a supply of epinephrine – a common treatment for allergic reactions – rather than leaving it up to campers to bring their own is a safe strategy with the lowest overall cost for everyone involved, the UVA researchers found.
“Stock, unassigned ...
What can tiny molecules in ants and naked mole-rats tell us about societal roles?
2025-06-24
Key Takeaways
Researchers led by Penn Integrates Knowledge Professor in the School of Arts & Sciences and the Perelman School of Medicine Shelley Berger explore the genetic basis of how communal-dwelling organisms like leafcutter ants and naked mole-rats divide labor among their societies
They discovered that pathways dating back hundreds of millions of years are conserved across animal kingdoms
Their findings offer fundamental insights into the origins of complex social behaviors and the neuroplasticity of assigned roles
From the bright lights of cities that don’t ...
National data shows post-pandemic rise in head and shoulder injuries for youth hockey players
2025-06-24
Journal: Injury
Title: Pediatric Ice Hockey Injury Trends Presenting to U.S. Emergency Departments: A 10-Year Review of National Injury Data
Authors: Luca M. Valdivia, MS, MD Candidate at the Icahn School of Medicine at Mount Sinai
Sheena Ranade, MD, Associate Professor of Orthopedics, and Pediatrics, at the Icahn School of Medicine at Mount Sinai
Bottom line: This study analyzes pediatric ice hockey injuries in emergency departments throughout the United States, finding a post-pandemic rise in head and shoulder injuries as well as hospitalizations.
Why this study is unique: This ...
The Vaccine Innovation Center of Korea University's College of Medicine successfully held a special seminar with Professor Pierre Van Damme
2025-06-24
On April 29th, the Vaccine Innovation Center (Director Chung Hee-Jin) of Korea University's College of Medicine successfully held a special seminar with Professor Pierre Van Damme, a world-renowned vaccine expert, at the Yoon Joo-Hong lecture room, 4th floor main building.
61 researchers joined this seminar to have in-depth discussions on the latest research trends and strategies in vaccine development and clinical trials.
Professor Pierre Van Damme is a world-renowned vaccine expert who has been selected as one of the 2025 recipient of the Park Man-Hoon Award for his contribution to lead the development of the first oral polio ...
Direct observation of the charge distribution at the ferroelectric interface was succeeded
2025-06-24
Multilayer ceramic capacitors (MLCCs) (1), which utilize ferroelectric ceramics, are widely used as electronic components in various devices such as smartphones, personal computers, televisions, and automotive systems. With the advancement of mobile devices, home appliances, and IoT technologies, there is an increasing demand for MLCCs to become more compact, offer higher capacitance, and exhibit greater reliability. MLCCs are structured with alternating layers of ferroelectric material and internal electrodes. Within the ferroelectric layers, there are domains with differing polarization directions, as well as domain interfaces on the nanometer (one-billionth of a ...
Sentinel-based index boosts tracking of Spartina alterniflora
2025-06-24
Researchers have unveiled a simple yet effective satellite-based tool to track Spartina alterniflora, one of the most aggressive invasive plant species threatening coastal wetlands. Using freely accessible Sentinel-2 imagery, the new Spartina alterniflora Index (SAI) enables precise, large-scale mapping of this fast-spreading species. Outperforming traditional vegetation indices and rivaling machine learning models in accuracy, SAI offers a scalable and practical solution for environmental monitoring and wetland protection.
Originally introduced to China in the 1970s to control erosion and support land ...
New protein targets for cancer treatments
2025-06-24
Cells depend on the precise reading of DNA sequences to function correctly. This process, known as gene expression, determines which genetic instructions are activated. When this fails, the wrong parts of the genome can be activated, leading to cancers and neurodevelopmental disorders. Scientists at the University of Geneva (UNIGE) have identified two proteins that play a key role in regulating this essential mechanism, paving the way for promising new treatments that could be more effective and less toxic than those currently available. Their findings are published in Nature Communications.
Human DNA contains over 20,000 genes and would stretch nearly two metres ...
New strategy for lead-free antiferroelectric design: Sn and Ce Co-doping regulates NaNbO₃ phase structure
2025-06-24
For decades, researchers have pursued lead-free alternatives to replace toxic yet high-performance lead-based antiferroelectrics (AFEs). Sodium niobate (NaNbO3, NN) emerged as a prime candidate due to its low cost and environmentally benign nature. However, its irreversible phase transition at room temperature, resulting in energy-wasting ferroelectric-like hysteresis, has hindered practical applications.
The team published their work in Journal of Advanced Ceramics on June 18, 2025.
Now, a materials scientists team has cracked this challenge through ions co-doping strategic. As published in Journal of Advanced Ceramics, co-doping NN with variable-valence elements Sn and Ce ...
AI tool set to transform characterisation and treatment of cancers
2025-06-24
A multinational team of researchers, co-led by the Garvan Institute of Medical Research, has developed and tested a new AI tool to better characterise the diversity of individual cells within tumours, opening doors for more targeted therapies for patients.
Findings on the development and use of the AI tool, called AAnet, have today been published in Cancer Discovery, a journal of the American Association for Cancer Research.
Not all tumour cells the same
Tumours aren't made up of just one cell type – they're a mix of different cells that grow and ...
COPD prevalence, disease burden varies significantly by state
2025-06-24
Miami (June 24, 2025) – Prevalence of chronic obstructive pulmonary disease (COPD) and the disease’s burden varies significantly by state. Understanding this variation could help address public health gaps to ease the burden on people with COPD and the health care system, according to a new study. The study is published in the March 2025 issue of Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation, a peer-reviewed, open-access journal.
COPD is an inflammatory lung disease, comprising several conditions, including chronic bronchitis and emphysema, and can ...
This blood protein could be spreading aging throughout your body
2025-06-24
For the first time in the world, a Korean research team discovered how cellular aging can spread systemically through the bloodstream—offering new insights and a potential therapeutic strategy to combat aging-related decline.
Professor Ok Hee Jeon's research group at the Department of Convergence Medicine, Korea University's College of Medicine, discovered that High Mobility Group Box 1 (HMGB1),a key extracellular senescence-associated secretory phenotype (SASP) factor, plays a ...
Official BRACELET-1 trial results indicate that adding the oncolytic virus immunotherapy pelareorep to paclitaxel chemotherapy warrants further investigation in HR+ HER2- metastatic breast cancer
2025-06-24
The official results of the BRACELET-01 (PrECOG 0113) trial have been published in Clinical Cancer Research, detailing the safety and efficacy of pelareorep, an investigational oncolytic virus immunotherapy, when added to paclitaxel chemotherapy, both with and without the checkpoint inhibitor avelumab. The trial included 48 patients with unresectable metastatic hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) tumors. All had experienced disease progression after receiving at least ...
Trusted oncology guidelines get a digital makeover: National Comprehensive Cancer Network launches NCCN Guidelines Navigator
2025-06-24
PLYMOUTH MEETING, PA [June 24, 2024] — The National Comprehensive Cancer Network® (NCCN®)—an alliance of leading cancer centers—announces a new, interactive digital delivery format for the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®). The NCCN Guidelines® are the recognized standard for clinical decision making and policy in cancer care and are the most thorough and frequently updated clinical practice guidelines available in any area of medicine. They assist in the decision-making process of individuals involved in cancer care and prevention—including ...
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