Connected methods guide
A better laboratory model: better for which question?
Connect organoids, synthetic compartments and neural experiments with a practical guide to what a model preserves, leaves out and can predict.
Read the guide · 4 minModels and their missing pieces
Two neural studies, an organoid and a synthetic compartment: connect what each model preserves with the question it can answer.
5 articles · About 16 minutes in total · Read at your own pace
Human stem-cell organoid development
Building two connected parts of the nervous system in one model
A dual neural organoid brings peripheral and central development into the same experimental setting. Its usefulness depends on the question it can faithfully represent.
Read the guide · 3 minSynthetic-compartment biophysics
Why a protein can behave differently in a crowded nucleus
DNA-built compartments reveal how environment reshapes protein condensation. The lesson is to test what a simplified experiment leaves out.
Read the guide · 3 minHuman neural recording and task decoding
The brain rehearses speech. Can a decoder follow?
New recordings explore silent speech rehearsal. The useful question is how a controlled syllable task might become a reliable communication tool.
Read the guide · 3 minCross-species neural time-series analysis
Under anesthesia, brain activity becomes more locally isolated
A cross-species analysis offers a common description of changing brain dynamics. It also shows why a shared pattern is only one part of a mechanism.
Read the guide · 3 min