Female victims of gun violence in the US are less likely to die than their male counterparts, despite having similar injury severity, finds a 7-year analysis of a US national injury database, published in the open access journal Trauma Surgery & Acute Care Open. They are also likely to have better outcomes, with fewer complications after hospital admission, the analysis shows. The US has the highest number of firearm deaths of all developed countries, and firearms injuries and deaths have been rising year on year, point out the researchers. And women are 21 times more likely to die from firearm injuries than their peers in any other developed nation. But it’s not ...

To curb the risk of falls, it may be worth grading skateboard parks like ski runs according to the popularity of the metal and concrete features they contain and the level of expertise required, conclude researchers in the journal Injury Prevention. Their analysis of the moves performed by more than 500 young skateboarders reveals that flips, jumps, and turns on flat ground and quarterpipe (a curved concave ramp) and ramp tricks seem to pose the greatest risk, and are universally popular. A grind box, ...

A major clinical trial, led by experts at the University of Nottingham, has shown that people with inflammatory conditions are able to improve the antibody response from a COVID-19 booster vaccination by interrupting their treatment for two weeks immediately after having the vaccine. The antibody response to the jab was doubled at four weeks, and one and a half times greater at 26 weeks, when compared to those who continued with their treatment as usual. The improved antibody response lasted for six months. Patients who interrupted treatment reported experiencing more flare-ups of their inflammatory conditions in the next few weeks, but most flares ...

Issues of identity, male-dominated branding and apprehension that their needs will go unmet are among the reasons women are not accessing veterans’ mental health support, according to new research being discussed today (Wednesday, 13 December) at a conference in Cambridge.   The report, I don’t feel like that’s for me: Overcoming barriers to mental healthcare for women veterans, was carried out by the Centre for Military Women’s Research (CMWR) at Anglia Ruskin University (ARU), to investigate the low numbers of ex-servicewomen engaging with veteran-specific mental health services.   The ...

WEST LAFAYETTE, Ind. — A climate policy that raises the price of carbon-intensive products across the entire U.S. economy would yield a side benefit of reducing nitrate groundwater contamination throughout the Mississippi River Basin. The Gulf of Mexico, an important U.S. fishery, also would see modest benefits from the nitrate reductions. These were among the conclusions of a recent study published in the Proceedings of the National Academy of Sciences (PNAS). The study, led by four early career researchers, three of them from ...

Berkeley — A 20-year experiment in the Sierra Nevada confirms that different forest management techniques — prescribed burning, restoration thinning or a combination of both — are effective at reducing the risk of catastrophic wildfire in California. These treatments also improve forest health, making trees more resilient to stressors like drought and bark beetles, and they do not negatively impact plant or wildlife biodiversity within individual tree stands, the research found. The findings of the experiment, called the Fire Surrogate Study, were published today in the journal Ecological Applications. “The research ...

Becoming a caregiver to an aging parent or spouse can be stressful, but a new study from a researcher at The University of Texas at Austin is questioning the idea that family caregiving is also a risk factor for depression. The study, published in the journal Advances in Life Course Research, found that depression in adult caregivers is mostly driven by having a loved one experiencing serious health problems, while becoming a caregiver is associated with fewer symptoms of depression. “Decades of research on this topic indicate that there are positive and negative aspects to being a caregiver,” said Sae Hwang Han, ...

University of Central Florida researcher Debashis Chanda, a professor at the NanoScience Technology Center, has developed a new technique to detect photons — elementary particles that span from visible light to radio frequencies and are instrumental in carrying cellular communication. The advancement could lead to more precise and efficient technologies in various fields, from improving medical imaging and communication systems to enhancing scientific research and even potentially bolstering security measures. Photon detection has typically relied on change/modulation of voltage or ...

Old, obese flies get healthier and live longer if put on a diet, University of Connecticut researchers report on Dec. 8 in PNAS. If the effect holds true for humans, it would mean it’s never too late for obese people to improve their health with diet. For way too many of us, eating too much goes along with getting old and a tendency to be obese. Different health organizations define obesity differently, but all agree it means having too much body fat, and is associated with a host of diseases related to metabolism including heart disease and diabetes. Many animal studies have shown that eating less—meaning sharply ...

ForestPaths’ first Policy Lab convened stakeholders in Helsinki, Finland, on 27-29 September 2023. Nineteen carefully selected participants with diverse expertise – including research, policy, governance, civil society, value chain professionals, and forestry practitioners – engaged in discussions on forest-based policymaking and modelling related to climate change and biodiversity. Tasked with considering policy actions given different timescales, governance paradigms, enablers, and barriers, participants contributed ...

“Mitochondrial dysfunction is a major cellular change observed in the hippocampus during aging.” BUFFALO, NY- December 12, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, “Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampus.” In this new study, researchers Hyo Young Jung, Hyun Jung Kwon, Kyu ...

In our everyday classical world, what you see is what you get. A ball is just a ball, and when lobbed through the air, its trajectory is straightforward and clear. But if that ball were shrunk to the size of an atom or smaller, its behavior would shift into a quantum, fuzzy reality. The ball would exist as not just a physical particle but also a wave of possible particle states. And this wave-particle duality can give rise to some weird and sneaky phenomena.  One of the stranger prospects comes from a thought experiment known as the “quantum bomb tester.” The experiment proposes that a quantum particle, such ...

Smoking shrinks the brain, according to a study by researchers at Washington University School of Medicine in St. Louis. The good news is that quitting smoking prevents further loss of brain tissue — but still, stopping smoking doesn’t restore the brain to its original size. Since people’s brains naturally lose volume with age, smoking effectively causes the brain to age prematurely, the researchers said. The findings, published in Biological Psychiatry: Global Open Science, help explain why smokers are at high risk of age-related cognitive decline and Alzheimer’s disease. “Up until recently, scientists have overlooked ...

PHILADELPHIA— Having the ability to self-schedule mammograms was associated with a 15 percentage point increase following through with getting the screening, according to research  from the Perelman School of Medicine at the University of Pennsylvania. The paper was published today in the American Journal of Preventive Medicine. “Self-scheduling helps make the path to mammogram completion a little smoother, where you don’t have to find the time to call a scheduling line, wait on hold, or go back and forth trying to find an appointment that works for your schedule,” said the study’s lead author, Kimberly Waddell, ...

PORTLAND, Oregon -- New research from Oregon Health & Science University could one day lead to therapies that prevent or treat diseases and infections tied to a protein that’s found in all human cells. A study published today in the journal Molecular Cell describes how the protein ubiquitin is modified during a bacterial infection. The study details the steps taken to create a form of the protein known as lysine 6 polyubiquitin, where a long chain of ubiquitin molecules are linked through ...

More than one-eighth of the randomized trials of cancer drugs seeking regulatory approval in China in recent years used inappropriate controls to test the effectiveness and safety of the drugs, according to a new study published December 12th in the open access journal PLOS Medicine by Professor Xiaodong Guan of Peking University, China, and colleagues. In randomized trials, patients are assigned to either a control arm, in which they receive the current optimal treatment, or an experimental arm, in which they receive the new drug being tested. However, studies have previously ...

MADISON – An interdisciplinary team led by University of Wisconsin–Madison scientists has developed a new technique that could help farmers extract useful nutrients such as ammonia and potassium from livestock manure to efficiently make fertilizer and other useful chemical products. While the strategy still needs to be scaled up beyond a proof-of-concept stage, the group's preliminary analyses show it could offer considerable benefits by cutting water and air pollution while simultaneously creating products that farmers could use or sell. Manure stinks in part because it contains ammonia, one of the more ...

DENVER/Dec. 12, 2023 – A new article published in the journal Methods in Ecology and Evolution by Morris Animal Foundation-funded researchers describes a simplified method to detect a deadly fungus killing European salamanders. The ability to rapidly find the fungus is significant as the disease, although not detected in the U.S., could impact the millions of amphibians and salamanders annually imported.  The fungal pathogen Batrachochytrium salamandrivorans, or Bsal, threatens salamander diversity. Initially identified in northern Europe, evidence suggests it was introduced from Southeast Asia via the pet trade.  “The impacts of Bsal ...

EMBO launches a new award for laboratory sustainability: The EMBO Lab Sustainability Award will recognize new and significant contributions to the development of sustainable wet and dry labs with a focus on their environmental impact. The award will be presented to an individual representing the initiative or project. Applications can be submitted between 15 January and 15 March 2024.  The award winner will have the opportunity to present their initiative or project at scientific events and publish a commentary in EMBO Reports. In addition, the winning project will be supported with a grant of 10,000 euros. The award is one of ...

ROCHESTER, Minn. — Stem cell-based therapy improved quality of life for patients with advanced heart failure, Mayo Clinic researchers and international collaborators discovered in a late-stage multinational clinical trial. In one of the largest studies of cell intervention after a heart attack, patients reported their daily hardship lessened when stem cells optimized for heart repair supplemented standard of care. This clinical study further documented lower death and hospitalization rates among those treated with cell therapy. This research ...

ABSTRACT: LBA-2 SAN DIEGO ― The targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (PFS) and achieved an overall remission rate in 82% of patients with relapsed/refractory mantle cell lymphoma (MCL), according to researchers at The University of Texas MD Anderson Cancer Center. Results from the Phase III SYMPATICO trial were presented at the 2023 American Society of Hematology (ASH) Annual Meeting. At a median follow-up of 51.2 months, median PFS was 31.9 months with the combination compared to 22.1 months with ibrutinib plus placebo. PFS benefits were consistent across patient subgroups, including those with blastoid-variant ...

DURHAM, N.C. – Identifying an older patient who is at risk for post-operative cognitive dysfunction might be done in the blink of an eye – literally.   Researchers at Duke Health found that a simple EEG measurement detects a signal of cognitive vulnerability when patients are asked to close, then open their eyes. Conducted prior to surgery, the non-invasive readout of brain waves helps predict which patients are at risk of post-operative confusion and attention problems.   “Roughly half of seemingly normal older adults experience problems with thinking, memory or attention after surgery,” said Leah Acker, M.D., Ph.D., assistant professor in ...

In April 2015, looters sacked an ancient cave burial at a site called Urd Ulaan Uneet high within the Altai Mountains of western Mongolia. When police apprehended the criminals, they uncovered, among other artifacts, an elegantly carved saddle made from several pieces of birch wood. Now, in a new study, researchers from Mongolia collaborating with University of Colorado Boulder archaeologist William Taylor have described the find. The team’s radiocarbon dating pins the artifact to roughly the 4th Century ...

UNIVERSITY PARK, Pa. — Self-propelled nanoparticles could potentially advance drug delivery and lab-on-a-chip systems — but they are prone to go rogue with random, directionless movements. Now, an international team of researchers has developed an approach to rein in the synthetic particles. Led by Igor Aronson, the Dorothy Foehr Huck and J. Lloyd Huck Chair Professor of Biomedical Engineering, Chemistry and Mathematics at Penn State, the team redesigned the nanoparticles into a propeller shape to better control their movements and increase their functionality. ...

Karandeep Singh, MD, has been recruited as the Joan and Irwin Jacobs Endowed Chair in Digital Health Innovation at University of California School of Medicine and named as the inaugural chief health artificial intelligence (AI) officer at UC San Diego Health, a newly developed position for the region’s only academic medical center. This new role will be effective December 29, 2023. In this position, Singh will focus on implementing change that advances safety and health outcomes in acute and ambulatory settings. His contributions will be pivotal in bringing innovation to ...