Integration of pharmacies with physician practices, where on-site pharmacies open at physician practice locations, is a growing trend in cancer treatment. However, little is known about how this integration affects drug utilization or expenditures, along with other aspects of the patient experience. A study published today in JAMA Network Open compared the outcomes of patients treated by oncologists whose practices integrated with pharmacies, to those of oncologists that did not integrate. Researchers found a slight increase in utilization of oral oncology drugs, but no significant change in expenditures on the drugs.  In addition, there were no discernible ...

CHICAGO –  Researchers from Penn Medicine’s Abramson Cancer Center (ACC) and the Perelman School of Medicine at the University of Pennsylvania will present data on the latest advances in cancer research at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, happening May 31—June 4, 2024 in Chicago and online. Follow @PennMedicine and @PennMDForum for updates. Expert interviews Experts from Penn Medicine are available to comment on a wide range of cancer research and care topics before, during, and after the meeting by video call, phone, or email. To arrange interviews, ...

A groundbreaking study led by UCLA Health has unveiled the most detailed view of the complex biological mechanisms underlying autism, showing the first link between genetic risk of the disorder to observed cellular and genetic activity across different layers of the brain.   The study is part of the second package of studies from the National Institutes of Health consortium, PsychENCODE. Launched in 2015, the initiative, chaired by UCLA neurogeneticist Dr. Daniel Geschwind, is working to create maps of gene regulation across different regions of the brain and different stages of brain development. The consortium aims to bridge the gap between studies ...

DALLAS, May 23, 2024 —According to American Heart Association data, 9 out of every 10 people who experience cardiac arrest outside of a hospital die. This is in part because they do not receive immediate cardiopulmonary resuscitation (CPR) more than half of the time. CPR, especially if performed immediately, can double or triple a person’s chance of survival. The American Heart Association and the Buffalo Bills want more people to be confident and capable when faced with a cardiac emergency. Through the HeartBEAT ...

Images Closing in on the theoretical maximum efficiency, devices for turning heat into electricity are edging closer to being practical for use on the grid, according to University of Michigan research.    Heat batteries could store intermittent renewable energy during peak production hours, relying on a thermal version of solar cells to convert it into electricity later.    "As we include higher fractions of renewables on the grid to reach decarbonization goals, we need lower costs and longer durations of ...

Researchers analyzing data from NASA’s James Webb Space Telescope have pinpointed three galaxies that may be actively forming when the universe was only 400 to 600 million years old. Webb’s data shows these galaxies are surrounded by gas that the researchers suspect to be almost purely hydrogen and helium, the earliest elements to exist in the cosmos. Webb’s instruments are so sensitive that they were able to detect an unusual amount of dense gas surrounding these galaxies. This gas will likely end up fueling the formation of new stars in the galaxies. “These ...

“The massive use of antibiotics and antimicrobials in people and animals has led to these substances appearing in unexpected environmental samples,” said Irantzu Vergara, researcher in the UPV/EHU’s IBeA group. Drugs that do not end up fully metabolised in the body reach the environment through various routes (such as manure, sewage sludge used as fertilisers, etc.), are leached into the soil and may end up transferring to crops or earthworms, which are at the base of the food chain. “Although ...

Collagen, a major component of the extracellular matrix, plays a crucial role in tumor development. During the development of tumors (“tumorigenesis”), collagen fibers become linearized and densely deposited, hindering immune cell infiltration and promoting tumor metastasis. However, quantifying these collagen changes during melanoma progression has been challenging. In-vivo imaging of collagen As reported in Biophotonics Discovery, researchers from the Morgridge Institute for Research and University of Wisconsin – Madison recently addressed this challenge by using quantitative imaging to visualize collagen ...

Noise-canceling headphones have gotten very good at creating an auditory blank slate. But allowing certain sounds from a wearer’s environment through the erasure still challenges researchers. The latest edition of Apple’s AirPods Pro, for instance, automatically adjusts sound levels for wearers — sensing when they’re in conversation, for instance — but the user has little control over whom to listen to or when this happens. A University of Washington team has developed an artificial intelligence system that lets a ...

HOUSTON – (May 23, 2024) – Lighting a gas grill, getting an ultrasound, using an ultrasonic toothbrush ⎯ these actions involve the use of materials that can translate an electric voltage into a change in shape and vice versa. Known as piezoelectricity, the ability to trade between mechanical stress and electric charge can be harnessed widely in capacitors, actuators, transducers and sensors like accelerometers and gyroscopes for next-generation electronics. However, integrating these materials into miniaturized systems has been difficult ...

In a study of nearly 200 young women who have survived breast cancer, most of those who tried to conceive were able to become pregnant and give birth   This study fills in major gaps from previous studies of fertility among breast cancer survivors   BOSTON – New research by Dana-Farber Cancer Institute investigators has encouraging news for young women who have survived breast cancer and want to have children. The study, which tracked nearly 200 young women treated for breast cancer, found that the majority of those who tried to conceive during a median of 11 years after treatment were able to become pregnant and give birth to a child. The findings, ...

Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), will share results of their work in 30 presentations at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting, which takes place May 31 – June 4 in Chicago. The clinical trials reported on in this work are led by SWOG and conducted by the NIH-funded NCI National Clinical Trials Network (NCTN) and the NCI Community Oncology Research ...

ABSTRACTS: 2018, 2517, 3513, 5504, 6016, 7007, 9515, 12017, LBA8007, LBA9516 CHICAGO ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. This special edition features presentations by MD Anderson researchers at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. In addition to the ...

Dae Hyun Kim, MD, ScD is the recipient of a 2024 A. Clifford Barger Excellence in Mentoring Award at Harvard Medical School. Kim is an associate scientist at the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife, an HMS Associate Professor of Medicine, a geriatrician at the Division of Gerontology in the Department of Medicine at Beth Israel Deaconess Medical Center, and a Harvard School of Public Health Instructor in the Department of Epidemiology. The Excellence in Mentoring Awards were established to recognize the value of quality mentoring ...

The results in Nature Communications find that symbiotic, nitrogen-fixing bacteria can ensure dominance among soil microbes due to its signalling-based communication with the legume plant host. Researchers discovered that when legumes need nitrogen, they will send out from the roots and into the soil specific molecules that are in turn recognized by the symbiotic bacteria to produce another molecule, the Nod factor which is recognized back by the legume plant. When this mutual recognition was established, the plant will modify the panel of root secreted molecules and by this will affect which soil bacteria can grow in the vicinity ...

­­­Colleen Ryan, associate vice provost in the Office of the Vice Provost for Faculty & Academic Affairs Indiana University Bloomington (IUB), has been named vice provost for faculty at Tufts University. She will start in the position on July 1. Ryan currently holds the rank of professor of Italian in the Department of French and Italian at IUB, is an affiliate faculty member in the Department of Gender Studies, and was the director of undergraduate studies for Italian from 2015-2023. Her areas of expertise ...

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail the many regulatory elements that coordinate the brain’s biological pathways and cellular functions. The research, supported the National Institutes of Health (NIH), used postmortem brain tissue from over 2,500 donors to map gene regulation networks across different stages of brain development and multiple ...

URBANA, Ill. – Parents are often eager to give their adolescent children advice about school problems, but they may find that youth are less than receptive to their words of wisdom. However, kids who don’t seem to listen to their parents may still benefit from their input, a new study from the University of Illinois Urbana-Champaign shows. The researchers looked at conversations between fifth-grade students and their mothers about academic problems, identifying mom’s advice strategies and the youth’s response. Then they correlated these findings with how ...

News Release Journal of Raptor Research For immediate release   Contact: [Zoey T. Greenberg] science.writer@raptorresearchfoundation.com 360.739.7170   Parents of the Year: Scavenging Raptors Lead a Collaborative Home Life    Let’s face it, scavengers have a bad reputation. However, according to a new paper published in the Journal of Raptor Research, pairs of scavenging falcons called Chimango Caracaras (Milvago chimango) demonstrate an endearing level of collaboration while raising their chicks. In their paper, “Biparental Care in a Generalist Raptor, the Chimango Caracara in Central Argentina” Diego Gallego-García from ...

Deciphering the genetic causes of common neurodevelopmental conditions like autism and common mental illnesses like bipolar disorder has been challenging – not least because of the size and complexity of the human brain – but a new package of research from a global group makes notable progress. Across Science, Science Translational Medicine, and Science Advances, more than a dozen reports from the PsychENCODE Consortium – established in 2015, and dedicated to illuminating the molecular ...

Study combines analyses of multiple genomic platforms over multiple brain regions to probe biological processes and underlying mechanisms of stress-related disorders Results lay groundwork for future diagnostics and targeted treatments BELMONT, Mass. (May 23, 2024) A comprehensive approach that examines the intersection of multiple biological processes is necessary to elucidate the development of stress-related disorders. In a new study, investigators from McLean Hospital, a member of the  Mass General Brigham healthcare system, ...

CORVALLIS, Ore. – What if a common element rather than scarce, expensive ones was a key component in electric car batteries? A collaboration co-led by an Oregon State University chemistry researcher is hoping to spark a green battery revolution by showing that iron instead of cobalt and nickel can be used as a cathode material in lithium-ion batteries. The findings, published today in Science Advances, are important for multiple reasons, Oregon State’s Xiulei “David” Ji notes. “We’ve transformed the reactivity of iron metal, the cheapest metal commodity,” he said. “Our electrode can offer a higher energy density ...

BELMONT, Mass. (May 23, 2024) Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging. In a new study, published May 23 is Science, a team led by McLean Hospital researchers used comprehensive genetic and cellular analyses to shed new light on the intricate molecular mechanisms underlying schizophrenia. Their new work provides a map for how the genes known to increase risk of schizophrenia affect specific cells within the brain. “We discovered which cell types express ...

The world’s population has increased by more than 2.6-fold in the last 60 years. The growing trend continues – projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8 billion in 2022. These numbers underscore the need for considering family planning; however, there have been limited breakthroughs in contraception in recent decades. Specifically for men, there are no oral contraceptive pills available. In a study published in the journal Science, researchers at Baylor College of Medicine and collaborating institutions show in animal models that a novel, non-hormonal sperm-specific approach offers a promising option ...

Artificial intelligence approaches demonstrate how plant science has evolved Machine learning also reveals how model systems have changed and how countries differ in terms of research focus and impact ##### In your coverage, please use this URL to provide access to the freely available paper in PLOS Biology:   http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002612 Article Title: Assessing the evolution of research topics in a biological field using plant science as ...