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T-cells infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

2023-08-30
CHAMPAIGN, Ill. — When an immunocompromised person’s system begins to recover and produce more white blood cells, it’s usually a good thing – unless they develop a potentially deadly inflammatory condition. New research from the University of Illinois Urbana-Champaign has found that the pulmonary distress often associated with the condition is caused not by damage to the lungs, but by newly populated T-cells infiltrating the brain.  Knowing this mechanism of action can help researchers and ...

The International Society of Microbiota will host a symposium dedicated to clinicians on probiotics and microbiota supplements applications in diseases

The International Society of Microbiota will host a symposium dedicated to clinicians on probiotics and microbiota supplements applications in diseases
2023-08-30
Venice, Italy – The International Society of Microbiota (ISM) is pleased to announce the upcoming symposium on probiotics and microbiota supplements. The symposium will take place on October 17, 2023, in Venice, Italy, one day prior to the 10th World Congress on Targeting Microbiota 2023. About ISM 2023 Symposium: The symposium will focus on the strain specificity of probiotics and microbiota supplements and their clinical applications for disease management. It will also elaborate on the use and mode of action of postbiotics and metabolites like the SCFA butyrate. Speakers will present the latest research on the use of probiotics to treat a variety ...

American Meteorological Society announces 2024 weather, water, and climate honorees

2023-08-30
[Boston, MA, USA—August 30, 2023]   Each year, the American Meteorological Society recognizes outstanding individuals and organizations in the weather, water, and climate community through its Awards and Honors program. The organization is proud to announce its 2024 recipients, who will receive their award or honor at the 104th AMS Annual Meeting in Baltimore, Maryland, 28 January–1 February, 2024. “Working across a wide range of sciences and services, the members of our community are vital to upholding safety and quality of life in the United States and across ...

Do driverless cars feel safe? New study shows gradual introduction needed to build comfort among all road users

Do driverless cars feel safe? New study shows gradual introduction needed to build comfort among all road users
2023-08-30
While self-driving vehicles (SDVs) are being hailed as a solution for safer, more efficient roads, new research suggests British Columbians are not quite ready to embrace self-driving cars wholeheartedly – and will need a period of gradual transition before adoption. The study, conducted by the Research on Active Transportation Lab (REACT) at the University of British Columbia, reveals mixed perceptions of automated vehicles, particularly their effects on pedestrian comfort and safety. Do self-driving cars feel safe? Four out of 10 participants (41 per cent) thought that pedestrians faced reduced safety and comfort levels ...

MD Anderson research highlights for August 30, 2023

2023-08-30
HOUSTON ― The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. Recent developments include a novel computational tool to detect single base pair DNA changes in single-cell sequencing data, a potential target to treat hypertension caused by drugs commonly used in organ transplants, further insights into the steps involved in ...

Study finds high blood and urinary metal levels among exclusive marijuana users

2023-08-30
Research conducted at Columbia University Mailman School of Public Health detected significant levels of metals in the blood and urine among marijuana users, concluding that marijuana may be an important and under-recognized source of lead and cadmium exposure. This is among the first studies to report biomarker metal levels among marijuana users and most likely the largest study to date, that links self-reported marijuana use to internal measures of metal exposure, rather than just ...

Bacteria treatment reduces insulin resistance, protects against diabetes

Bacteria treatment reduces insulin resistance, protects against diabetes
2023-08-30
Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a type of gut bacteria that might help improve insulin resistance, and thus protect against the development of obesity and type-2 diabetes. The study, published August 30 in the scientific journal Nature, involved genetic and metabolic analysis of human fecal microbiomes and then corroborating experiments in obese mice. Insulin is a hormone released by the pancreas in response to blood sugar. Normally, it helps get the sugar ...

Researchers identify stem cells in the thymus for the first time

Researchers identify stem cells in the thymus for the first time
2023-08-30
Francis Crick Institute press release Under strict embargo: 16:00hrs BST 30 August 2023 Peer reviewed Experimental study Cells Researchers identify stem cells in the thymus for the first time Researchers at the Francis Crick Institute have identified stem cells in the human thymus for the first time. These cells represent a potential new target to understand immune diseases and cancer and how to boost the immune system. The thymus is a gland located in the front part of the chest, the place where thymocytes (the cells in the thymus) mature into T ...

New ‘droplet battery’ could pave the way for miniature bio-integrated devices

New ‘droplet battery’ could pave the way for miniature bio-integrated devices
2023-08-30
UNDER EMBARGO UNTIL 16:00 BST / 11:00 ET WEDNESDAY 30 AUGUST 2023 Researchers have developed a miniature battery that could be used to power tiny devices integrated into human tissues. The design uses an ionic gradient across a chain of droplets – inspired by how electric eels generate electricity. The device was able to regulate the biological activity of human neurons. This could open the way to the development of tiny bio-integrated devices, with a range of applications in biology and medicine. University of Oxford researchers have made a significant step towards realising miniature ...

Study finds how some ion channels form structures permitting drug delivery

Study finds how some ion channels form structures permitting drug delivery
2023-08-30
A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine. The discovery is a significant advance in cell biology, likely solves a long-standing mystery about an unusual feature of some ion channels and has implications for the development of drugs targeting these proteins and for drug delivery. Ion channels are ubiquitous in the cell membranes of higher organisms. ...

Discoveries on memory mechanisms could unlock new therapies for Alzheimer’s and other brain diseases

2023-08-30
  AURORA, Colo. (Aug. 30, 2023) – Scientists at the University of Colorado Anschutz Medical Campus have made a `paradigm shifting’ discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer’s disease and potentially Down syndrome. The study was published Wednesday in the journal Nature. For over 30 years, researchers believed that LTP or long-term potentiation, which is crucial for learning and memory, required enzymatic actions by an enzyme known as CaMKII. But a team of researchers led by Ulli ...

Newly engineered versions of bacterial enzyme reveal how antibiotics could be more potent

2023-08-30
Modern medicine depends on antibiotics to treat infections by disabling targets inside bacterial cells. Once inside these cells, antibiotics bind to certain sites on specific enzyme targets to stop bacterial growth. Randomly occurring changes (mutations) in the genes for these targets occur naturally, in some cases making the target harder for the antibiotic to attach to, and that bacterial version resistant to treatment. For this reason, the more antibiotics have been used over time, the greater the chances that bacterial populations will evolve to have mutants resistant to existing antibiotics, and the more urgent the call for new approaches ...

World’s coastal wetlands and coral reef islands are hanging by a thread, new study shows

2023-08-30
Coastal wetlands and coral reef islands will struggle to grow fast enough to keep pace with rising sea levels driven by climate change, according to a new study published in Nature. The study was conducted by an international team that includes a Tulane University researcher. The findings show that the future of marshes and other low-lying coastal areas depend heavily on whether global warming can be limited to less than 2 degrees Celsius (3.6 degrees Fahrenheit) as formulated by the Paris Agreement. A key finding of the paper is that coastal marshes, mangroves, ...

A simpler way to connect quantum computers

A simpler way to connect quantum computers
2023-08-30
Researchers have a new way to connect quantum devices over long distances, a necessary step toward allowing the technology to play a role in future communications systems. While today’s classical data signals can get amplified across a city or an ocean, quantum signals cannot. They must be repeated in intervals — that is, stopped, copied and passed on by specialized machines called quantum repeaters. Many experts believe these quantum repeaters will play a key role in future communication networks, allowing enhanced security and enabling connections between remote quantum computers. The Princeton study, published Aug. ...

Parental incarceration increases cardiovascular risk in young adults

2023-08-30
Cardiovascular disease remains the leading cause of racial disparities in mortality between Black and white people in the United States. New research from the University of Chicago Medicine suggests that parental incarceration may be contributing to these health gaps. According to the new study, people who experienced a parent or parental figure’s incarceration anytime before the age of 18 had higher levels of hypertension and coronary disease biomarkers than people whose parents were not incarcerated. These results indicate that mass incarceration may have transgenerational health consequences. Adverse childhood experiences (ACEs) are difficult ...

Unveiling global warming’s impact on daily precipitation with deep learning

Unveiling global warming’s impact on daily precipitation with deep learning
2023-08-30
A collaborative international research team led by Professor Yoo-Geun Ham from Chonnam National University and Professor Seung-Ki Min from Pohang University of Science and Technology (POSTECH) has made a discovery on the impact of global warming on global daily precipitation. Using a deep learning approach, they have unveiled a significant change in the characteristics of global daily precipitation for the first time. Their research findings were published on August 30 in the online version of Nature, the ...

Challenge accepted: High-speed AI drone overtakes world-champion drone racers

Challenge accepted: High-speed AI drone overtakes world-champion drone racers
2023-08-30
Remember when IBM’s Deep Blue won against Gary Kasparov at chess in 1996, or Google’s AlphaGo crushed the top champion Lee Sedol at Go, a much more complex game, in 2016? These competitions where machines prevailed over human champions are key milestones in the history of artificial intelligence. Now a group of researchers from the University of Zurich and Intel has set a new milestone with the first autonomous system capable of beating human champions at a physical sport: drone racing. The AI system, called Swift, won multiple races against three world-class champions in first-person view (FPV) ...

Could a cancer drug hold the key to a HIV cure?

Could a cancer drug hold the key to a HIV cure?
2023-08-30
An existing blood cancer drug has shown promise in killing ‘silent’ HIV cells and delaying reinfections – a significant pre-clinical discovery that could lead to a future cure for the disease. Hidden HIV cells, known as latent infection, are responsible for the virus permanently remaining in the body and cannot be treated by current therapy options. These hibernating, infected cells are the reason why people living with HIV require life-long treatment to suppress the virus. Led by WEHI and The Peter Doherty Institute for Infection ...

Robustness of the world's skyscrapers stress-tested by Surrey model

2023-08-30
The safety of tall buildings in the world's cities, in the face of extreme external traumas like vehicle impacts, blasts or fires, has been tested using a model developed by structural engineers at the University of Surrey – with reassuring results.  Surrey's structural engineers partnered with industry experts to check and enhance the robustness of skyscrapers. Surrey's researchers collaborated with experts at the respected collective of architects, designers, engineers and planners, Skidmore, Owings & Merrill (SOM), famous for buildings like the Burj Khalifa, the world's tallest skyscraper, and the Sears ...

Inequities in cardiovascular care are putting older female’s heart health at risk

Inequities in cardiovascular care are putting older female’s heart health at risk
2023-08-30
Toronto, ON, August 30, 2023 – Higher stroke risk among females with atrial fibrillation may be related to sex-based disparities in cardiovascular care, according to a new study from Women’s College Hospital, the Peter Munk Cardiac Centre (PMCC) at University Health Network (UHN) and ICES. Atrial fibrillation (AF) is a common type of irregular heart rhythm that is associated with a higher risk of stroke—after the age of 40, one in four strokes are caused by AF. Previous studies have found that female sex (assigned at birth) is a risk factor for AF-associated stroke. Recent research suggested that ...

Surprising study results: Students are bored during exams

2023-08-30
In the case of boredom, we think of many situations in life but intuitively not of exams. However, an international team of academics led by Thomas Götz from the University of Vienna has now studied exactly this phenomenon of test boredom for the first time and found remarkable results. According to the study, school students are actually very bored during exams. The study also showed that utter boredom has a negative effect on exam results. The research results have been published recently in the Journal of Educational Psychology.  Although boredom is currently a very intensively studied phenomenon, test boredom has so far been completely ignored ...

Study reveals important associations between gut microbiome and eczema in infancy

2023-08-30
Washington, D.C. –  A new study has revealed important associations between the gut microbiome and eczema in infancy and has established the basis for the potential prevention and treatment of eczema via modulation of the gut microbiota. The study was published in mSystems, a journal of the American Society for Microbiology. “The problem of eczema is increasing, and our study shows it could be a result of unwanted changes in the gut bacterial content. The first year of life could be a critical period to restore the gut bacteria to a more desirable composition,” said the study’s principal investigator ...

Adapting Ritalin® to tackle cocaine abuse

2023-08-30
Cocaine use continues to be a public health problem, yet despite concerted efforts, no drugs have been approved to resolve cocaine addiction. Research suggests that the attention-deficit/hyperactivity disorder drug methylphenidate (MPH; Ritalin®) could serve as a cocaine-replacement therapy, but clinical results have been mixed. Although several labs have produced MPH derivatives for testing, parts of the molecule remained chemically inaccessible. Now, researchers reporting in ACS Central Science have cleared that hurdle. According to the Centers for Disease Control and Prevention, more than 5 million Americans ...

A new way to capture and recycle carbon dioxide from industrial emissions

2023-08-30
Carbon capture is a promising method to help slow climate change. With this approach, carbon dioxide (CO­­2) is trapped before it escapes into the atmosphere, but the process requires a large amount of energy and equipment. Now, researchers reporting in ACS Central Science have designed a capture system using an electrochemical cell that can easily grab and release CO2. The device operates at room temperature and requires less energy than conventional, amine-based carbon-capture systems. Many industries are turning ...

Nuclear weapons tests are unappreciated source of radioactivity in German wild boars

2023-08-30
Shaggy-haired, tusked pigs roam free in the woods of Germany and Austria. Although these game animals look fine, some contain radioactive cesium at levels that render their meat unsafe to eat. Previously, scientists hypothesized that the contamination stemmed from the 1986 Chernobyl nuclear power plant accident. But now, researchers in ACS’ Environmental Science & Technology report that nuclear weapon fallout from 60 to 80 years ago also contributes significantly to the wild boars’ persistent radioactivity. Radioactive cesium, a byproduct of nuclear weapons explosions and nuclear ...
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