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Associations of military-related traumatic brain injury with new-onset mental health conditions and suicide risk

2023-07-31
About The Study: In this study including 860,000 soldiers, rates of new-onset mental health conditions were higher among individuals with a history of military-related traumatic brain injury (TBI) compared with those without. Moreover, risk for suicide was both directly and indirectly associated with history of TBI.   Authors: Lisa A. Brenner, Ph.D., of the VHA Rocky Mountain Mental Illness Research Education and Clinical Center in Aurora, Colorado, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link ...

Association of racial and ethnic identity with attrition from M.D.-Ph.D. Training programs

2023-07-31
About The Study: This study found significant racial and ethnic disparities in attrition from M.D.-Ph.D. training, where Black students had greater than 50% higher odds of leaving M.D.-Ph.D. training than their peers. Notably, compared with 17% of white students, 29% of Black M.D.-Ph.D. students did not complete their training.  Authors: Mytien Nguyen, M.S., of the Yale School of Medicine in New Haven, Connecticut, is the corresponding author. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamainternmed.2023.2822) Editor’s ...

Association between gestational age and academic achievement of children born at term

2023-07-31
About The Study: The findings of this study of more than 500,000 children suggest that there is no evidence of a difference in math and reading scores over grades 2 to 11 among children born between 39 and 40 weeks’ gestation, and overall no evidence of better scores among those born at 41 weeks’ gestation compared with 40 weeks’ gestation. The results can further inform decisions on delivery timing at term birth by offering insights into long-term associations of delivery timing with cognitive development and school achievement.  Authors: George L. Wehby, M.P.H., Ph.D., of ...

CABBI develops eco-friendly enzyme to create key chemical building blocks

CABBI develops eco-friendly enzyme to create key chemical building blocks
2023-07-31
Using energy from light to activate natural enzymes can help scientists create new-to-nature enzymatic reactions that support eco-friendly biomanufacturing — the production of fuels, plastics, and valuable chemicals from plants or other biological systems. Applying this photoenzymatic approach, researchers have developed a clean, efficient way to synthesize crucial chemical building blocks known as chiral amines, solving a longstanding challenge in synthetic chemistry. The study, published in Nature Catalysis, ...

When electrons slowly vanish during cooling

When electrons slowly vanish during cooling
2023-07-31
Many substances change their properties when they are cooled below a certain critical temperature. Such a phase transition occurs, for example, when water freezes. However, in certain metals there are phase transitions that do not exist in the macrocosm. They arise because of the special laws of quantum mechanics that apply in the realm of nature’s smallest building blocks. It is thought that the concept of electrons as carriers of quantized electric charge no longer applies near these exotic phase transitions. Researchers at the University of Bonn and ETH Zurich have now ...

BU commentary: Including sexual and gender minority populations in medical research guarantees the health and well-being of all

2023-07-31
(Boston)—In the face of ongoing political threats to the rights and well-being of sexual and gender minority (SGM) populations, public health and health care institutions and practitioners must explicitly address the needs of marginalized populations while ensuring that those with multiple marginalized identities are well represented in research, according to a commentary in JAMA Network Open.  “If we continue to exclude SGM in research, we will remain oblivious to the troubles they face in achieving health and well-being,” said lead author Carl G. Streed, Jr., MD, MPH, FACP, ...

Luzio, who lived in São Paulo 10,000 years ago, was Amerindian like Indigenous people now, DNA reveals

Luzio, who lived in São Paulo 10,000 years ago, was Amerindian like Indigenous people now, DNA reveals
2023-07-31
An article to be published on July 31 in Nature Ecology & Evolution reveals that Luzio, the oldest human skeleton found in São Paulo state (Brazil), was a descendant of the ancestral population that settled the Americas at least 16,000 years ago and gave rise to all present-day Indigenous peoples, such as the Tupi. Based on the largest set of Brazilian archeological genomic data, the study reported in the article also offers an explanation for the disappearance of the oldest coastal communities, who built the icons of Brazilian archeology known as sambaquis, huge mounds of shells and fishbones used as dwellings, cemeteries and territorial boundaries. Archeologists often ...

Bees evolved from ancient supercontinent, diversified faster than suspected

Bees evolved from ancient supercontinent, diversified faster than suspected
2023-07-31
The first bees evolved on an ancient supercontinent more than 120 million years ago, diversifying faster and spreading wider than previously suspected, a new study shows. Led by Washington State University researchers, the study provides a new best estimate for when and where bees first evolved. Newly published in the journal Current Biology, the project reconstructed the evolutionary history of bees, estimated their antiquity, and identified their likely geographical expansion around the world. The results indicate their point of origin was in western Gondwana, an ancient supercontinent that at that time included today's continents of Africa and South America. “There’s ...

New algorithm ensnares its first ‘potentially hazardous’ asteroid

New algorithm ensnares its first ‘potentially hazardous’ asteroid
2023-07-31
Link to Google Drive folder containing images, videos and caption/credit information: https://drive.google.com/drive/folders/19LP7UZbVKkTXSFds6DaKSy1lp014Hw4z?usp=sharing   Link to release: https://www.washington.edu/news/2023/07/31/heliolinc3d/   FROM: James Urton University of Washington +1 206-543-2580 jurton@uw.edu      Ranpal Gill Vera C. Rubin Observatory +1 520-309-6195 rgill@lsst.org   Note: Researcher contact information at the end     For ...

Fascination of Science: 60 Encounters with Pioneering Researchers of Our Time

Fascination of Science: 60 Encounters with Pioneering Researchers of Our Time
2023-07-31
What makes a brilliant scientist? Who are the people behind the greatest discoveries of our time? Connecting art and science, photographer Herlinde Koelbl seeks the answers in this English translation of the German book Fascination of Science, an indelible collection of portraits of and interviews with sixty pioneering scientists of the twenty-first century. Koelbl's approach is intimate and accessible, and her highly personal interviews with her subjects reveal the forces (as well as the personal quirks) that motivate the scientists' work; for example, one wakes up at 3 am because ...

Team identifies key driver of cancer cell death pathway that activates immune cells

Team identifies key driver of cancer cell death pathway that activates immune cells
2023-07-31
CHAMPAIGN, Ill. — Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers. They report their findings in the journal Cancer Research.  “Most anticancer drugs cause cancer cells to shrivel up and die in a controlled process known as apoptosis. But apoptosis does not usually strongly activate immune cells,” said David Shapiro, a professor ...

Scrambler therapy may offer lasting relief for chronic pain, review paper suggests

Scrambler therapy may offer lasting relief for chronic pain, review paper suggests
2023-07-31
FOR IMMEDIATE RELEASE A new review paper co-authored by two Johns Hopkins pain experts suggests that scrambler therapy, a noninvasive pain treatment,  can yield significant relief for approximately 80%–90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS). The write-up was published online July 13 in The New England Journal of Medicine. Scrambler therapy, approved by the U.S. Food and Drug Administration in 2009, administers electrical stimulation through the skin via electrodes placed in areas of the body above and below where chronic pain is felt. The goal is to capture the nerve endings ...

Icahn School of Medicine at Mount Sinai receives $11.5 million grant renewal to study the impact of psychosocial stress on cardiovascular disease

2023-07-31
New York, NY (July 31, 2023)—Psychosocial stress profoundly affects people’s lives globally, not least because it can be a critical risk factor for cardiovascular disease. Thanks to an $11.5 million award renewal from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, distinguished researchers at the Icahn School of Medicine at Mount Sinai and elsewhere aim to gain a deeper understanding of how stress influences cardiovascular health. “To address residual cardiovascular risk in patients, our research program aims to bolster our mechanistic understanding ...

Way cool: UVA professor developing ‘freeze ray’ technology for the Air Force

Way cool: UVA professor developing ‘freeze ray’ technology for the Air Force
2023-07-31
You know that freeze-ray gun that “Batman” villain Mr. Freeze uses to “ice” his enemies? A University of Virginia professor thinks he may have figured out how to make one in real life. The discovery – which, unexpectedly, relies on heat-generating plasma – is not meant for weaponry, however. Mechanical and aerospace engineering professor Patrick Hopkins wants to create on-demand surface cooling for electronics inside spacecraft and high-altitude jets. “That’s the primary problem right now,” Hopkins said. “A lot of electronics on board heat up, but they have no way to cool down.” The U.S. Air Force likes the prospect of a freeze ...

Bees likely evolved from ancient supercontinent, earlier than suspected

Bees likely evolved from ancient supercontinent, earlier than suspected
2023-07-31
PULLMAN, Wash. –The origin of bees is tens of millions of years older than most previous estimates, a new study shows.  A team led by Washington State University researchers traced the bee genealogy back more than 120 million years to an ancient supercontinent, Gondwana, which included today’s continents of Africa and South America. In a study that proposes a new evolutionary history of bees, the researchers found evidence that bees originated earlier, diversified faster and spread wider than many scientists previously suspected. They published their findings in the journal Current ...

Routinely drinking alcohol may raise blood pressure even in adults without hypertension

2023-07-31
Research Highlights: An analysis of data from seven studies involving more than 19,000 adults in the United States, Korea and Japan found a clear association between increases in systolic (top-number) blood pressure and the number of alcoholic beverages consumed daily. Even people who drank one alcoholic beverage per day showed a link to higher blood pressure when compared to non-drinkers, reinforcing the American Heart Association’s advice to limit alcohol intake and to not start drinking alcohol if you do not already. Embargoed until ...

This disease can be caused by a food allergy and prevent children from eating. A new study may show how to treat it

2023-07-31
A new study from Tulane University has identified a new treatment for a chronic immune system disease that can prevent children from eating. Eosinophilic esophagitis (EoE) is triggered by food allergies or airborne allergens which causes a type of white blood cell, eosinophils, to build up in the lining of the esophagus. This causes the esophagus to shorten and the esophageal wall to thicken, making swallowing difficult and causing food to get stuck in the throat. The disease occurs in an estimated 1 in 2,000 adults but more frequently affects children (1 in 1,500) where symptoms can be harder to diagnose and pose greater risks as difficulty feeding can lead to malnutrition, weight loss and ...

Oxycodone prescriptions after delivery not linked to longer-term opioid use compared to codeine prescriptions

2023-07-31
Postpartum prescriptions for oxycodone were not associated with increased risk of longer-term opioid use compared to codeine prescriptions, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221351. Over the last 10 years, there has been a shift to fewer codeine prescriptions and an increase in prescriptions for stronger opioids, such as hydrocodone, hydromorphone and oxycodone for patients postpartum. “This occurred in part ...

Novel vaccine may hold key to prevent or reduce the impact of Alzheimer’s disease

2023-07-30
Research Highlights: A novel vaccine that targets a protein involved in Alzheimer’s disease helped eliminate toxic cells in mice with the condition. After vaccination, the mice had fewer amyloid plaques and less inflammation in brain tissue and showed improvement in behavior and awareness. Embargoed until 12 p.m. CT/1 p.m. ET, Sunday, July 30, 2023 BOSTON, July 30, 2023 — A novel vaccine that targets inflamed brain cells associated with Alzheimer’s disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association’s Basic Cardiovascular Sciences Scientific ...

To spread or slide? Scientists uncover how foams are spread on surfaces

To spread or slide? Scientists uncover how foams are spread on surfaces
2023-07-29
Tokyo, Japan – Researchers from Tokyo Metropolitan University have uncovered the physics behind how foams are spread on surfaces. Balls of foam placed on a flat substrate were scraped across with a plate and observed. They identified different patterns which strongly depend on the scraping speed, governed by competing physical phenomena. Their findings apply to all kinds of soft materials that need to be spread evenly on surfaces, from mayonnaise on bread to insulation on walls.   Whether ...

How to save the NHS – an expert prescription

2023-07-29
Whether it’s setting up a Bank of England-type body to run it or fining patients for missing appointments, healthcare leaders, policymakers and practitioners past and present have a wealth of ideas about how they would change the NHS for the better. Professor Dinesh Bhugra, a psychiatrist and former president of the British Medical Association and the Royal College of Psychologists, asked 14 peers, physicians and patients’ representatives for their prescription for the NHS. The interviews are reproduced in Professor Bhugra’s new book, Conversations about the NHS.  Thought-provoking and in some cases, controversial, ideas include: Setting ...

Unlocking a mystery of fetal development

2023-07-28
As with many toxins, exposure to the toxic metal cadmium during pregnancy can adversely impact fetal development. Now, researchers at the Rutgers School of Public Health think they’re beginning to understand how the metal inflicts its damage: by disrupting placental hormones that regulate pregnancy physiology.   Unlike other toxins, relatively little cadmium crosses the placenta to directly impact the fetus. Instead, the placenta concentrates cadmium in its tissue at rates of up to six times that found in umbilical cord serum.   “We already know a lot about cadmium and its detrimental impacts on fetal health, such ...

How breast milk boosts the brain

2023-07-28
A new study by scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University suggests that a micronutrient in human breast milk provides significant benefit to the developing brains of newborns, a finding that further illuminates the link between nutrition and brain health and could help improve infant formulas used in circumstances when breastfeeding isn’t possible. The study, published July 11 in the Proceedings of the National Academy of Sciences (PNAS),  also paves the way to study what role this micronutrient might play in the brain as ...

New study findings underscore the importance of timely newborn screenings in early care for cystic fibrosis

New study findings underscore the importance of timely newborn screenings in early care for cystic fibrosis
2023-07-28
Aurora, Colo. (July 28, 2023) – The Journal of Pediatrics has published a manuscript by Stacey Martiniano, MD, pulmonary specialist at Children’s Hospital Colorado and associate professor of pediatrics at the University of Colorado. Dr. Martiniano was primary author on the study titled, Late Diagnosis in the Era of Universal Newborn Screening Negatively Effects Short- and Long-Term Growth and Health Outcomes in Infants with Cystic Fibrosis. The manuscript’s senior author was Susanna McColley, MD, professor of pediatrics in pulmonary and sleep medicine at Northwestern University Feinberg ...

Royal Society of Chemistry honors Hong with fellow selection

Royal Society of Chemistry honors Hong with fellow selection
2023-07-28
The Royal Society of Chemistry has named Yi Hong, a distinguished university professor of bioengineering at The University of Texas at Arlington, as a fellow. Hong said he was honored by the selection. “Chemistry is amazing because it helps to create many new biomedical materials for human health and life saving,” Hong said. “This recognition encourages me not only to invent more creative biomaterials through chemical design for disease treatment, but also to be a role model to our next generation of scientists and engineers ...
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