Washington (May 14, 2024) — Studies examining the risks of GLP-1 weight-loss drugs, distinguishing alpha-gal syndrome from other GI disorders, and comparing medications to slow the progression of liver disease in patients with alcohol-use disorder will be presented this week at Digestive Disease Week (DDW) 2024. Abstracts are available to registered media. Embargos lift at 12:01 a.m. EDT on the day they are presented. Here are summaries of the new research: Re-examining the risks of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists for weight loss with more stringent criteria on a comprehensive ...

An exceptional $8 million, 10-year philanthropic investment will spearhead new treatments for pancreatic cancer and create a new dedicated research centre at WEHI. The centre, to be established thanks to an investment by Australian business leader and WEHI President Jane Hemstritch AO, aims to help close the significant survival gap between pancreatic cancer and other cancers. The Hemstritch Centre of Excellence for Pancreatic Cancer Research will provide a leading team of scientists and clinicians with long-term funding to ask big research questions. They aim to make major ...

Recently, an international team led by Prof. GE Jian from the Shanghai Astronomical Observatory of the Chinese Academy of Sciences conducted a search for rare weak signals in quasar spectral data released by the Sloan Digital Sky Survey III (SDSS-III) program using deep learning neural networks. By introducing a new method to explore galaxy formation and evolution, the team showcased the potential of artificial intelligence (AI) in identifying rare weak signals in astronomical big data. This study was published ...

Technology (SIAT) of the Chinese Academy of Sciences, in collaboration with researchers at Central China Normal University, have developed a high-performance perovskite X-ray complementary metal-oxide-semiconductor (CMOS) detector for medical imaging. The study was published in Nature Communications on Feb. 21. X-ray imaging is vital for the diagnosis and treatment of cardiovascular and cancer diseases. Direct-conversion X-ray detectors made of semiconductor materials exhibit superior spatial and temporal resolution at lower radiation doses compared to indirect-conversion detectors made of scintillator materials. However, the currently available semiconductor ...

By Jade Boyd Special to Rice News Pioneering Rice University chemist Gustavo Scuseria has won the 2024 Schrödinger Medal from the World Association of Theoretical and Computational Chemists. Awarded annually to a single recipient, the medal recognizes an outstanding body of work in theoretical and computational chemistry. Scuseria has pioneered quantum computational methods that are widely used to study the complex quantum states and electronic properties of a wide range of molecules and materials. In awarding the medal, ...

□ DGIST (President Kunwoo Lee) announced on the 16th (Tue) that a research team led by Professor Jaehong Lee of the Department of Robotics and Mechanical Electronics has developed a new human implantable, wireless, health monitoring electronic suture system through joint research with a team from Yonsei University and Korea University. The developed wireless electronic suture can be easily applied in the medical field and is expected to be used in various orthopedic fields, such as patient-customized rehabilitation. □ ...

KYOTO, Japan – May 20, 2024 Infertility affects approximately 1 in 6 people in their lifetime worldwide according to the World Health Organization (WHO). Infertility —as defined by the American Society for Reproductive Medicine (ASRM)— is a disease, condition, or status characterized by “the inability to achieve a successful pregnancy based on a patient’s medical, sexual, and reproductive history, age, physical findings, diagnostic testing, or any combination of those factors” or requiring medical intervention such as the use of mature donor gametes “to achieve a successful pregnancy ...

Ikoma, Japan – With the growth of the Internet of Things, sustainable solution for powering wireless sensors and devices are considered important. Thermoelectric generators, for example, which have the ability to convert waste heat into electricity can offer a sustainable solution. Researchers around the world have been working on such solutions. A research team, led by Masakazu Nakamura from Nara Institute of Science and Technology (NAIST), Japan has also been working on flexible wearable thermoelectric generators that produce electricity from body heat by sewing nanomaterial called carbon nanotubes (CNTs) into fabric. Effective ...

The authors of a major study on the Critically Endangered Arabian leopard say that the release of captive bred animals carefully selected for their genes can make a significant contribution to the successful recovery of the dwindling wild population and avert the prospect of extinction.   An international collaboration led by scientists from the Durrell Institute of Conservation and Ecology (DICE) at the University of Kent, University of East Anglia (UEA), University College London (UCL), Nottingham-Trent University (NTU) and the Diwan of Royal Court in Oman, surveyed the remote Dhofar mountain range of southern Oman to determine how many of Arabia’s last big cat survive.   By ...

For Wendy Hood and Geoffrey Hill in Biological Sciences, Andreas Kavazis in Kinesiology, and their team, Emma Rhodes, Paulo Mesquita, and Jeff Yap, traveling the country to unlock the mystery of mitochondria in migrating aviary species has allowed them to make a significant contribution to research in an area that has not been investigated before. The first publication conducted in the AU MitoMobile van is featured in Scientific Reports, “Flexibility underlies differences in mitochondrial respiratory performance between ...

BIRMINGHAM, Ala. – Chronic obstructive pulmonary disease patients with type 2 inflammation may soon gain access to a new drug — dupilumab — that showed rapid and sustained improvements in patients in a pivotal Phase 3 clinical trial, researchers report in the New England Journal of Medicine. This monoclonal antibody is the first biologic shown to improve clinical outcomes in COPD. The data supporting the use of dupilumab in COPD will be reviewed by the United States Food and Drug Administration in June. The disease improvements — as measured by a significantly ...

Embargoed for release until 5:00 p.m. ET on Monday 20 May 2024     Annals of Internal Medicine Tip Sheet      @Annalsofim     Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent.     ----------------------------     1. ...

Purdue-led fishing expedition nets new pupfish family member in New Mexico Genetic drift, not natural selection, identified as main factor driving speciation WEST LAFAYETTE, Ind. Scientists have identified a new member on the genetic family tree of an endangered pupfish native to south-central New Mexico. “We went into this thinking that there was one species of conservation concern,” said J. Andrew DeWoody, professor of genetics in Purdue University’s Department of Forestry and Natural Resources. “The preponderance of evidence ...

BOSTON--Yoga, mindfulness, meditation, breathwork, and other practices are gaining in popularity due to their potential to improve health and well-being. The effects of these practices are mostly positive and occasionally transformational, yet they are known to sometimes be associated with challenging altered states of consciousness. New research by a team including investigators from Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, reveals that altered states of consciousness associated with meditation practice are far more common than expected. Although many people reported positive outcomes, that were sometimes even considered ...

Cislunar space, which stretches from the Earth to just beyond the moon’s orbit, is about to become heavily trafficked over the next 10 years. With NASA’s planned Artemis missions and other countries joining in the cislunar space race, there’s an interest in observing, tracking and predicting the orbit of objects like asteroids and satellites so they don’t collide with spacecraft. But the process of detecting and observing space objects, known as space domain awareness (SDA), faces challenges with the extensive volume of cislunar space. “Cislunar space is vast,” says Tarek Elgohary, an associate professor ...

A sensory process such as pain is no ordinary phenomenon—it’s a symphony of neural and vascular interactions orchestrated by the brain and spinal cord. Attempting to dissect this symphony by focusing on a single region is like trying to understand a complex melody by listening to just one instrument. It’s incomplete, potentially misleading, and may result in erroneous conclusions. Enter the Carney Institute’s team of visionaries. Their mission? To develop tools that allow unprecedented observation of neural and vascular activity within the brain and spinal cord. They tackled two critical fronts: imaging hardware and bioluminescent (BL) molecular tools. Innovative ...

A certain biological pathway, a set of linked reactions in the body, drives the inflammation seen in the skin disease psoriasis, a new study finds. The work could lead to improved therapies for all inflammatory skin diseases, including atopic and allergic dermatitis and a type of boil called hidradenitis suppurativa, say the study authors. Inflammation is the body’s natural response to irritation and infection, but when out of control, it can lead to the reddish, flaky, itchy lesions that come with these skin diseases. Led by researchers at NYU Langone Health, the new study found that the interleukin-17 (IL-17) pathway, ...

Research Assistant Professor Christopher Fowler received the NASA 2023 Planetary Science Early Career Award for his project “Bringing Planetary Science to West Virginia”. The award is based on demonstrated leadership, involvement in the planetary science community, and potential for future impact.    The resources provided by the NASA Planetary Science Early Career Award will allow Fowler and team to undertake research-related activities that are not always possible within the scope of more “traditional” ...

“[...] we have characterized a pair of compounds that impact multiple processes that are relevant to cancer cell proliferation but also, and possibly more importantly, to metastasis [...].” BUFFALO, NY- May 20, 2024 – A new research paper was published in Oncotarget's Volume 15 on May 16, 2024, entitled, “The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response.” The diheteroarylamide-based compound 1C8 and the aminothiazole carboxamide-related compound GPS167 inhibit the CLK kinases, and affect ...

Aging is contributing at the 2024 Systems Aging Gordon Research Conference in Barcelona, Spain, from June 2–7. BUFFALO, NY- May 20, 2024 – Aging is a contributor at the 2024 Systems Aging Gordon Research Conference (GRC) on “Systems Modeling, Aging Biomarkers, and Longevity Interventions” — taking place from June 2–7, 2024, in Castelldefels, Barcelona, Spain. “The conference will present recent advances in systemic rejuvenation, multi-omics approaches, applications ...

The shortage of suitable donor meniscus grafts from the knee and temporomandibular joint (TMJ) impedes treatments for millions of patients. Vitrification offers a promising solution by transitioning these tissues into a vitreous state at cryogenic temperatures, protecting them from ice crystal damage using high concentrations of cryoprotectant agents (CPAs). However, vitrification's success is hindered for larger tissues (>3 mL) due to challenges in CPA penetration. Dense avascular meniscus tissues require extended CPA exposure for adequate penetration; however, ...

CHAMPAIGN, Ill. —  By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein. Their report, in the Proceedings of the National Academy of Sciences, offers an unprecedented view of the sequence of hydrogen-bonding events that occur when a protein morphs from an unfolded to a folded state. See video: Protein Sonification “A protein must fold properly to become an enzyme or signaling molecule or whatever its function may be — all the many things that proteins do in our bodies,” said University of Illinois ...

New York, NY [May 20, 2024]—Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair. Using tiny fat particles loaded with genetic instructions to calm down inflammation, the treatment was shown to target problem-causing cells and reduce swelling and harmful molecules in mouse models of damaged skin. Details on their findings were published in the May 20 online issue of the Proceedings of the National Academy of Sciences (PNAS). Diabetic wounds, often resistant to conventional treatments, ...

Irvine, Calif., May 20, 2024 — A team of glaciologists led by researchers at the University of California, Irvine used high-resolution satellite radar data to find evidence of the intrusion of warm, high-pressure seawater many kilometers beneath the grounded ice of West Antarctica’s Thwaites Glacier. In a study published today in Proceedings of the National Academy of Sciences, the UC Irvine-led team said that widespread contact between ocean water and the glacier – a process that is replicated throughout Antarctica and in Greenland – causes “vigorous melting” and may require a reassessment of ...

EMBARGOED UNTIL 15:00 EDT MONDAY, MAY 20, 2024 For the first time, there is visible evidence showing that warm seawater is pumping underneath Antarctica’s Thwaites Glacier—ominously nicknamed the Doomsday Glacier. An international team of scientists—including a researcher from the University of Waterloo—observed it using satellite imagery and warns that it could accelerate catastrophic sea level rise in 10 to 20 years.  The intrusion of seawater causes the ice to continuously lift off the land and settle back down again. Ice melts intensely when it first touches seawater, ...