LOS ANGELES — City of Hope®, one of the largest cancer research and treatment organizations in the United States, has been awarded $5.4 million from the California Institute for Regenerative Medicine (CIRM) to build and fund a stem cell research laboratory on its Duarte, California, campus that will further expand its scientific capabilities. The mission of the unique Stem Cell-Based Disease Modeling Laboratory is two-fold. First, it will advance stem cell-based disease modeling to spur innovation in regenerative medicine. The laboratory leverages City of Hope’s infrastructure ...

Thousands of top nutrition experts will gather next month for a dynamic program of research announcements, policy discussions and award lectures at NUTRITION 2024, the annual flagship meeting of the American Society for Nutrition. Reporters and bloggers are invited to apply for a complimentary press pass to attend the meeting in Chicago from June 29–July 2.   Explore the meeting schedule and register for a press pass to attend.   Hot topics to be explored at NUTRITION 2024 include:   Diet and cancer ...

A World Health Organization Essential Medicine, ketamine is widely used at varying doses for sedation, pain control, general anesthesia and as a therapy for treatment-resistant depression. While scientists know its target in brain cells and have observed how it affects brain-wide activity, they haven’t known entirely how the two are connected. A new study by a research team spanning four Boston-area institutions uses computational modeling of previously unappreciated physiological details to fill that gap and offer new insights into how ketamine works. “This modeling work has helped decipher likely mechanisms through which ...

How do migrants choose their destinations? Existing models, known as “gravity models,” use population size and travel distance as explanatory variables—and often fail, especially at the neighborhood scale. Many migrants prefer to move to a location near friends, family, or co-nationals. This pattern might be partly driven by factors that repeat (such as the cost of living) and partly driven by homophily, the tendency to interact with similar others. Early migrants tend to reduce uncertainty and provide information for later arrivals. Building on these observations, Rafael Prieto-Curiel and colleagues construct a migration model based on the power of the diaspora to ...

Extreme heat can harm human health, but so can temperature extreme swings. Large daily temperature variation (DTV) has been associated with elevated mortality in studies around the world. Trees and other vegetation can lower DTV, as trees reduce temperature through transpiration during the day and also trap long-wave radiation in the atmosphere under the canopy at night, increasing temperature. But green space is not equally distributed in most cities. Shengjie Liu and Emily Smith-Greenaway examined inequality in DTV exposure in the US, using monthly nighttime and daytime land surface temperature data from satellites. ...

COLUMBUS, Ohio – Online video game players believe the behavior known as “smurfing” is generally wrong and toxic to the gaming community – but most admit to doing it and say some reasons make the behavior less blameworthy, new research finds.   The new study suggests that debates about toxicity in gaming may sometimes be more complex and nuanced than is often acknowledged, according to the researchers.   Online video games use what are called “matchmaking systems” to pair players based on skill. “Smurfing” is when players cheat these systems by creating new accounts so that they can play against people lower ...

When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies. Cancer cells function in turbo mode: Their metabolism is programmed for rapid proliferation, whereby their genetic material is also constantly copied and translated into proteins. As researchers led by Professor Gennaro De Libero from the University of Basel and the University ...

A group of scientists from Nagoya University in Japan has used a specialized microscopic technique to observe the internal reproduction process of the Arabidopsis plant. Their findings, published in EMBO Reports, reveal the mechanism behind a female flower selectively attracting a single male counterpart. These findings provide insights that may help optimize seed production and improve agricultural breeding practices. Angiosperms, commonly referred to as flowering plants, have male and female reproductive organs. In the process of plant reproduction, when a pollen grain that ...

Inside a lab in Boston University’s College of Engineering, a robot arm drops small, plastic objects into a box placed perfectly on the floor to catch them as they fall. One by one, these tiny structures—feather-light, cylindrical pieces, no bigger than an inch tall—fill the box. Some are red, others blue, purple, green, or black.  Each object is the result of an experiment in robot autonomy. On its own, learning as it goes, the robot is searching for, and trying to make, an object with the most efficient ...

What is the largest ligament in the human body? It might surprise some people that it is the Achilles tendon. Even though it is also considered the toughest ligament, the Achilles tendon can rupture, with many such injuries involving sports enthusiasts in their 30s or 40s. Surgery might be required, and a prolonged period of rest, immobilization, and treatment can be difficult to endure. Seeking to shorten the recovery time, a research team led by Osaka Metropolitan University Graduate School of Medicine’s Katsumasa Nakazawa, a graduate student in the Department of Orthopedic Surgery, Associate Professor ...

Technology use is at an all-time high and understanding how this impacts daily life is crucial. When it comes to parent-child interactions, scientists have coined the term ‘technoference,’ meaning technology interference. It occurs when parent-child interaction and communication are disrupted by the use of digital devices. But is distraction caused by digital devices more detrimental to parent-child interaction than when parental distraction comes from different sources? Researchers in Switzerland have investigated. “In this study, we show that ...

Mobile phones have become invaluable for receiving emergency alerts such as weather warnings, evacuation notices and notifications about missing persons. In Japan, where earthquakes are frequent, they are vital for delivering earthquake warnings and advising people to take protective actions beforehand. To deal with such situations promptly, the Earthquake Early Warning (EEW) system sends out notifications to areas expected to experience strong tremors by detecting primary seismic waves (P-waves) that arrive before the secondary waves (S-waves). However, the short time between receiving the notification and the arrival of S-waves ...

Homelessness doesn’t only happen to young people but also affects older adults in growing numbers, write authors in an analysis in CMAJ (Canadian Medical Association Journal) that describes this emerging crisishttps://www.cmaj.ca/lookup/doi/10.1503/cmaj.231493. People experiencing homelessness are considered older adults at age 50, as visible aging is often evident at younger ages in individuals experiencing homelessness compared with individuals who have secure housing. Individuals experiencing homelessness often develop chronic ...

More than 1 in 5 adults in Canada did not have access to primary care, with large regional gaps in access, found new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.231372. “Translated to the population of Canada, our survey estimates that more than 6.5 million adults across the country don’t have access to a family doctor or nurse practitioner they can see regularly,” says Dr. Tara Kiran, a family physician and researcher at the MAP Centre for Urban Health Solutions at St. Michael’s Hospital, Unity Health Toronto and the University ...

Washington (May 14, 2024) — Studies examining the risks of GLP-1 weight-loss drugs, distinguishing alpha-gal syndrome from other GI disorders, and comparing medications to slow the progression of liver disease in patients with alcohol-use disorder will be presented this week at Digestive Disease Week (DDW) 2024. Abstracts are available to registered media. Embargos lift at 12:01 a.m. EDT on the day they are presented. Here are summaries of the new research: Re-examining the risks of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists for weight loss with more stringent criteria on a comprehensive ...

An exceptional $8 million, 10-year philanthropic investment will spearhead new treatments for pancreatic cancer and create a new dedicated research centre at WEHI. The centre, to be established thanks to an investment by Australian business leader and WEHI President Jane Hemstritch AO, aims to help close the significant survival gap between pancreatic cancer and other cancers. The Hemstritch Centre of Excellence for Pancreatic Cancer Research will provide a leading team of scientists and clinicians with long-term funding to ask big research questions. They aim to make major ...

Recently, an international team led by Prof. GE Jian from the Shanghai Astronomical Observatory of the Chinese Academy of Sciences conducted a search for rare weak signals in quasar spectral data released by the Sloan Digital Sky Survey III (SDSS-III) program using deep learning neural networks. By introducing a new method to explore galaxy formation and evolution, the team showcased the potential of artificial intelligence (AI) in identifying rare weak signals in astronomical big data. This study was published ...

Technology (SIAT) of the Chinese Academy of Sciences, in collaboration with researchers at Central China Normal University, have developed a high-performance perovskite X-ray complementary metal-oxide-semiconductor (CMOS) detector for medical imaging. The study was published in Nature Communications on Feb. 21. X-ray imaging is vital for the diagnosis and treatment of cardiovascular and cancer diseases. Direct-conversion X-ray detectors made of semiconductor materials exhibit superior spatial and temporal resolution at lower radiation doses compared to indirect-conversion detectors made of scintillator materials. However, the currently available semiconductor ...

By Jade Boyd Special to Rice News Pioneering Rice University chemist Gustavo Scuseria has won the 2024 Schrödinger Medal from the World Association of Theoretical and Computational Chemists. Awarded annually to a single recipient, the medal recognizes an outstanding body of work in theoretical and computational chemistry. Scuseria has pioneered quantum computational methods that are widely used to study the complex quantum states and electronic properties of a wide range of molecules and materials. In awarding the medal, ...

□ DGIST (President Kunwoo Lee) announced on the 16th (Tue) that a research team led by Professor Jaehong Lee of the Department of Robotics and Mechanical Electronics has developed a new human implantable, wireless, health monitoring electronic suture system through joint research with a team from Yonsei University and Korea University. The developed wireless electronic suture can be easily applied in the medical field and is expected to be used in various orthopedic fields, such as patient-customized rehabilitation. □ ...

KYOTO, Japan – May 20, 2024 Infertility affects approximately 1 in 6 people in their lifetime worldwide according to the World Health Organization (WHO). Infertility —as defined by the American Society for Reproductive Medicine (ASRM)— is a disease, condition, or status characterized by “the inability to achieve a successful pregnancy based on a patient’s medical, sexual, and reproductive history, age, physical findings, diagnostic testing, or any combination of those factors” or requiring medical intervention such as the use of mature donor gametes “to achieve a successful pregnancy ...

Ikoma, Japan – With the growth of the Internet of Things, sustainable solution for powering wireless sensors and devices are considered important. Thermoelectric generators, for example, which have the ability to convert waste heat into electricity can offer a sustainable solution. Researchers around the world have been working on such solutions. A research team, led by Masakazu Nakamura from Nara Institute of Science and Technology (NAIST), Japan has also been working on flexible wearable thermoelectric generators that produce electricity from body heat by sewing nanomaterial called carbon nanotubes (CNTs) into fabric. Effective ...

The authors of a major study on the Critically Endangered Arabian leopard say that the release of captive bred animals carefully selected for their genes can make a significant contribution to the successful recovery of the dwindling wild population and avert the prospect of extinction.   An international collaboration led by scientists from the Durrell Institute of Conservation and Ecology (DICE) at the University of Kent, University of East Anglia (UEA), University College London (UCL), Nottingham-Trent University (NTU) and the Diwan of Royal Court in Oman, surveyed the remote Dhofar mountain range of southern Oman to determine how many of Arabia’s last big cat survive.   By ...

For Wendy Hood and Geoffrey Hill in Biological Sciences, Andreas Kavazis in Kinesiology, and their team, Emma Rhodes, Paulo Mesquita, and Jeff Yap, traveling the country to unlock the mystery of mitochondria in migrating aviary species has allowed them to make a significant contribution to research in an area that has not been investigated before. The first publication conducted in the AU MitoMobile van is featured in Scientific Reports, “Flexibility underlies differences in mitochondrial respiratory performance between ...

BIRMINGHAM, Ala. – Chronic obstructive pulmonary disease patients with type 2 inflammation may soon gain access to a new drug — dupilumab — that showed rapid and sustained improvements in patients in a pivotal Phase 3 clinical trial, researchers report in the New England Journal of Medicine. This monoclonal antibody is the first biologic shown to improve clinical outcomes in COPD. The data supporting the use of dupilumab in COPD will be reviewed by the United States Food and Drug Administration in June. The disease improvements — as measured by a significantly ...