Genetic testing of IVF-created embryos could help more women over 35 have a baby in less time, a clinical trial by researchers from King’s College London, King’s College Hospital, and King’s Fertility has found. Published today in the Journal of Clinical Medicine, this is the first randomised controlled trial worldwide to focus exclusively on women aged 35–42, a group at higher risk of producing embryos with chromosomal abnormalities. The trial looked at the use of Preimplantation genetic testing for aneuploidy (PGT-A) to check embryos ...

COLUMBUS, Ohio – Having a hard time bending over to put your shoes on? Experiencing pain in the knees, groin, thigh or back? A new survey by The Ohio State University Wexner Medical Center reveals many people don’t realize these symptoms can mean there’s a problem in the hip. The survey of 1,004 people in the United States shows 72% are not aware that knee pain can actually be a sign of a hip problem. Similarly, 69% miss groin pain and 66% miss thigh pain as rooted in the hip. “Patients will be referred to me for knee pain,” explained Matthew Beal, MD, an orthopedic surgeon at Ohio State Wexner Medical Center. “When I examine the patient, ...

Tobacco smoking is the number one cause of preventable disease and death in Canada; it is highly addictive and hard to stop. Recognizing these challenges, a new guideline from the Canadian Task Force on Preventive Health Care provides a menu of effective options to help people quit smoking, with behavioural and medication options and a natural health product that can be tailored and combined for personal choice. The guideline is published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.241584. “Quitting ...

Dr. Dong-Soo Han's research team at the Korea Institute of Science and Technology (KIST) Semiconductor Technology Research Center, in collaboration with the research teams of Prof. Jung-Il Hong at DGIST and Prof. Kyung-Hwan Kim at Yonsei University, has developed a device principle that can utilize "spin loss," which was previously thought of as a simple loss, as a new power source for magnetic control. Spintronics is a technology that utilizes the "spin" property of electrons to store and control information, and it is being recognized as a key foundation for next-generation information processing technologies such as ultra-low-power ...

A recent review of the Canadian Task Force on Preventive Health Care underscores the need for expert bodies to produce evidence-based guidance and that Canada should ensure a renewed task force is adequately funded and supported, argues a commentary in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.251038. Dr. Vivek Goel, President and Vice-Chancellor of the University of Waterloo and author of the commentary, chaired the External Expert Review panel that reviewed the task force’s structure, ...

Children residing in “very low-opportunity” neighborhoods are up to 20 times more likely to be hospitalized for gun injuries than those living in the most advantaged areas, reports a new multi-state study published in Pediatrics. The study also found that most hospitalizations for gun injuries among children under 18 are the result of unintentional shootings — incidents caused by mishandling or accidental discharge of a gun. “The fewer opportunities a child has in their neighborhood, the greater their odds of ending up in the hospital with a firearm injury,” said co-author Dr. Mehul Raval, Head of Pediatric ...

Study analyzed nearly 7,000 pediatric gun injuries and mapped odds by ZIP code Kids in ‘low-opportunity’ neighborhoods far more likely to be shot than those in ‘high-opportunity’ areas ‘High-opportunity’ kids are far less likely to be shot, but twice as likely to die when it happens Authors stress urgent need for safe storage and firearm safety education CHICAGO --- Children residing in “very low-opportunity” neighborhoods are up to 20 times more likely to be hospitalized ...

The first study of its kind to compare cardiovascular risk in type 1 diabetes (T1D) and type 2 diabetes (T2D) in both men and women shows that younger men with T2D have worse mortality and cardiovascular disease (CVD) outcomes than those with T1D, whereas for women of all ages, almost all outcomes are worse for T1D than for T2D. The study is by Dr Vagia Patsoukaki, Uppsala University, Uppsala, Sweden, and colleagues and is presented at this year’s Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September). CVD is the leading cause of death and morbidity worldwide and individuals with ...

Osaka, Japan – Optical microscopy is a key technique for understanding dynamic biological processes in cells, but observing these high-speed cellular dynamics accurately, at high spatial resolution, has long been a formidable task. Now, in an article published in Light: Science & Applications, researchers from The University of Osaka, together with collaborating institutions, have unveiled a cryo-optical microscopy technique that take a high-resolution, quantitatively accurate snapshot at a precisely selected timepoint in dynamic ...

A line of engineering research seeks to develop computers that can tackle a class of challenges called combinatorial optimization problems. These are common in real-world applications such as arranging telecommunications, scheduling, and travel routing to maximize efficiency. Unfortunately, today’s technologies run into limits for how much processing power can be packed into a computer chip, while training artificial-intelligence models demands tremendous amounts of energy. Researchers at UCLA and UC Riverside have demonstrated a new approach that overcomes these ...

  Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men. While early-stage disease can be effectively managed, advanced forms—particularly metastatic castration-resistant prostate cancer (mCRPC)—pose significant therapeutic hurdles. A growing body of evidence highlights the pivotal role of SOX transcription factors, with SOX2 emerging as a central driver in tumor growth, spread, and resistance to therapy.   SOX2 is intricately linked to the fate of cancer stem/progenitor cells, influencing processes ...

  The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material. These regions, long overlooked due to their non-protein-coding nature, are now known to harbor ...

  The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver conditions. As a member of the glycoside hydrolase family 18, CHI3L1 is recognized for its unique ability to bind to ligands and influence multiple pathophysiological processes, despite lacking enzymatic activity. This distinctive protein plays a key role in mediating cell proliferation, inflammation, fibrosis, and carcinogenesis.   Liver diseases, including hepatitis-related fibrosis, non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease ...

Reston, VA (August 22, 2025)—New research has been published ahead-of-print by The Journal of Nuclear Medicine (JNM). JNM is published by the Society of Nuclear Medicine and Molecular Imaging, an international scientific and medical organization dedicated to advancing nuclear medicine, molecular imaging, and theranostics—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes. Summaries of the newly published research articles are provided below. Mapping Tiny Lifetimes ...

Center for BrainHealth® at The University of Texas at Dallas is proud to announce that one of its flagship programs, Charisma™ Virtual Social Coaching, has been selected as a Top 3 Finalist for the 2025 Global Innovation Management Institute (GIMI) Innovation Award in the category of Most Innovative Project – Social Sector/Non-Profit. GIMI is the world’s largest certifying body and professional organization for innovation and innovation management. The Innovation Awards recognize projects that demonstrate exceptional creativity, measurable impact and scalable solutions across public, private and social sectors. With ten award categories, the competition ...

A new study published by researchers at the University of Hawai‘i (UH) at Mānoa sheds light on the critical role of iron in Earth’s climate history, revealing how its sources in the South Pacific Ocean have shifted over the past 93 million years. This groundbreaking research, based on the analysis of deep-sea sediment cores, provides crucial insights into the interplay between iron, marine life, and atmospheric carbon dioxide levels. Iron is a vital nutrient for marine life and plays a significant role in regulating atmospheric carbon dioxide by influencing the growth of phytoplankton, which absorb carbon dioxide. Although the importance of iron ...

UCL Press Release Peer-reviewed | modelling study | people Under embargo until Friday 22 August 2025, 19:00 UK time / 14:00 US Eastern time   US oil and gas air pollution causes unequal health impacts Air pollution from oil and gas is causing 91,000 premature deaths and hundreds of thousands of health issues across the United States annually, with Black, Asian, Native American and Hispanic groups consistently the most affected, finds a major new study led by researchers at UCL and the Stockholm Environment Institute (SEI). The research, published in Science Advances, is the first to comprehensively quantify the health impacts of outdoor air pollution across ...

Methane — a potent greenhouse gas — constantly seeps from the ocean floor and can rise into the atmosphere. Now, an international team led by scientists with the USC Dornsife College of Letters, Arts and Sciences has uncovered how tiny microorganisms work together as a living electrical network to consume some of this gas before it escapes, acting as a powerful living filter.  By revealing how these microbes naturally reduce methane emissions, the findings could lead to innovative strategies ...

A University of Massachusetts Amherst kinesiologist has received a five-year, $2 million grant from the National Institutes of Health (NIH) to advance his research on how myosin molecules—molecular motors crucial for muscle contraction— work together to drive different processes within cells. This multi-pronged research will lead to a better understanding of many important myosin-related functions, from how our muscles and heart contract to how the ear’s stereocilia facilitate hearing. The long-term goal is to use these findings to pinpoint the causes of dysfunction in myosin-associated diseases and to identify ...

From November 18-22, 2024, four peers from Spain, Portugal, and Italy, selected by the European Commission, carried out an on-site mission in Land Brandenburg under the Union Civil Protection Mechanism (UCPM) Peer Review Programme. Requested by the authorities of Land Brandenburg in cooperation with the Federal Office of Civil Protection and Disaster Assistance (BBK), the review assessed wildfire risk governance and practice to provide actionable pathways for strengthening capabilities. CMCC experts served as facilitators, leveraging experience from previous disaster risk management and wildfire peer reviews in Romania (2022), Moldova (2023), ...

Organic chemistry, the chemistry of carbon compounds, is the basis of all life on Earth. However, metals also play a key role in many biochemical processes. When it comes to “marrying” large, heavy metal atoms with light organic compounds, nature often relies on a specific group of chemical structures: porphyrins. These molecules form an organic ring; in its center, individual metal ions such as iron, cobalt, or magnesium can be “anchored”. The porphyrin framework forms the basis for hemoglobin in human blood, photosynthetic chlorophyll in plants, and numerous ...

Excessive amounts of visceral fat — the hidden fat surrounding organs — is linked with faster ageing of the heart, a new study has found. Ageing is the biggest risk factor for heart disease, but why some people age faster than others isn’t fully understood. The scientists leading the research say that visceral body fat could play an important role in accelerating ageing of the heart and blood vessels. This type of fat is known to be harmful to health and this study now links it to faster heart ageing. The study, led by scientists from the Medical Research Council (MRC) Laboratory ...

Offering a modest gift card significantly increased enrollment of low-income individuals in a patient registry designed to accelerate Alzheimer’s disease clinical trials, a new USC study finds. Why it matters: Effective strategies are needed to improve representation of marginalized groups in Alzheimer’s clinical trials. Despite ongoing debate among researchers about the ethics of financial incentives for clinical trial enrollment, there has been little consensus on the appropriate use and size of incentives. About the experiment: Nearly 50,000 adults 50 and older without a dementia diagnosis were invited over ...

About The Study: This study found that, in U.S. adults, disaster-induced displacement from home was associated with increased odds of depression and anxiety symptoms, with the highest odds among those who never returned home. There is an urgent need to address mental health care for populations displaced by natural disasters, particularly socially vulnerable populations. Corresponding Author: To contact the corresponding author, Ther W. Aung, PhD, email twa21@case.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.28546) Editor’s ...

About The Study: This cross-sectional study found that Asian and Pacific Islander, Black, and Hispanic transgender and gender diverse beneficiaries had a high prevalence of cardiovascular-related conditions and had an elevated prevalence of several conditions, attributable to the intersection of gender, race, and ethnicity. Medicare should use the tools at its disposal to support the health of transgender and gender diverse beneficiaries. Corresponding Author: To contact the corresponding author, Gray Babbs, MPH, ...